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The map label for this gene is rbsK [H]

Identifier: 39546369

GI number: 39546369

Start: 3716637

End: 3717584

Strand: Direct

Name: rbsK [H]

Synonym: STM3547.Sc

Alternate gene names: 39546369

Gene position: 3716637-3717584 (Clockwise)

Preceding gene: 16766832

Following gene: 16766834

Centisome position: 76.51

GC content: 42.41

Gene sequence:

>948_bases
ATGAAAAATAATGTATGTGTTATTGGCTCGTTCAATGTTGATATTATCAGTTATCTACCGAGATTACCCTCAACGGGAGA
ATCATTGCTGGCCGATAAATTTATTTTTTCACCCGGCGGTAAGGGATGTAATCAGGCATTAGCAGCAAGCTATGCCGATT
CTGATGTGCATTTTATTACTAAAGTCGGCTCAGATCATTTTAGTGATTACGCCATTAATTTTATAAACTCATCAAAAATC
CATAAAAGTGTTATCTACCAGACCAAAGAAACACAAACAGGTACAGCAACCATCATGGTGAATGGAGATACCGGAGATAA
CGTCATCGCTATCTACCCTGGCGCCAACATGACAATTTCCCCTGATGAAATCACCATTCAGAAAGAAGCCATTGTTCATT
CAGATATTGTTCTTGTCCAACTGGAGACGAATTACGAAGCGCTGCAGCAAACAATTCGTCTCGCACAAAAAAATGACATA
CCGGTCATCATCAATCCAGCGCCGTACAATGACATGGTTAACACCATCATTGATAACATTGATTATATTACGCCAAATGA
AACGGAAGCAGGCCTGCTGGCCAATATGGCGGTTAATGATATCGAATCAGCCAAATGCGCGGCCAAAATTATTCATCAGA
AAGGCGTCAAAAATACCATTATTACATTAGGTAGCAAAGGTTCGCTTGCTTATGATGGCACACAATTCATCTATTCCCCG
GCATTTCCGGCAGTTGTAAAAAATACGGCGGGAGCGGGTGACGCTTTCAATGGTGCCCTCGCATCTGGTCTTGCAAAAGG
AAAGTCACTGGCATCCGCATTGTGCTACGCCAGCGCATTTGCCTCACTTGCGGTTGAAACGCCTAATGCCTCTGATATGC
CGGAAAACGACTCCGTTCTTCATCGTATTCAGGGTTCACATTACAAACAAACTATCTCTACTCACTAA

Upstream 100 bases:

>100_bases
TATTACCCTTGATTCTCTTGATAACGTCGCAAAAAATGAAATTGCTTATGTGCTGGAAAAATATGAATCAGCGCAGAAAA
TAAAAAAAGGTCTCTCTGCC

Downstream 100 bases:

>100_bases
ATCAAGGAGCAGACTATGAACAATACGCAGAAAAAACTAAAGGTGCTCTTTATTGGAGAATCCTGGCATATTCATATGAT
TCATTCAAAAGGTTATGACA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYAINFINSSKI
HKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIVHSDIVLVQLETNYEALQQTIRLAQKNDI
PVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAYDGTQFIYSP
AFPAVVKNTAGAGDAFNGALASGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQTISTH

Sequences:

>Translated_315_residues
MKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYAINFINSSKI
HKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIVHSDIVLVQLETNYEALQQTIRLAQKNDI
PVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAYDGTQFIYSP
AFPAVVKNTAGAGDAFNGALASGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQTISTH
>Mature_315_residues
MKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYAINFINSSKI
HKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKEAIVHSDIVLVQLETNYEALQQTIRLAQKNDI
PVIINPAPYNDMVNTIIDNIDYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAYDGTQFIYSP
AFPAVVKNTAGAGDAFNGALASGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRIQGSHYKQTISTH

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=262, Percent_Identity=33.206106870229, Blast_Score=135, Evalue=7e-32,
Organism=Escherichia coli, GI1790193, Length=272, Percent_Identity=36.0294117647059, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1788491, Length=298, Percent_Identity=26.1744966442953, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082343, Length=299, Percent_Identity=25.0836120401338, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788017, Length=258, Percent_Identity=24.8062015503876, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=286, Percent_Identity=34.6153846153846, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319884, Length=323, Percent_Identity=28.7925696594427, Blast_Score=96, Evalue=6e-21,
Organism=Drosophila melanogaster, GI20128807, Length=298, Percent_Identity=33.8926174496644, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24583886, Length=277, Percent_Identity=28.5198555956679, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33581; Mature: 33581

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFIT
CCCCEEEEEECCHHHHHHCCCCCCCCHHHHHHHEEECCCCCCHHHHHHHHCCCCCEEEEE
KVGSDHFSDYAINFINSSKIHKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTIS
ECCCCCCCCCEEEECCCCHHHHHHHEECCCCCCCEEEEEEECCCCCCEEEEECCCCCEEC
PDEITIQKEAIVHSDIVLVQLETNYEALQQTIRLAQKNDIPVIINPAPYNDMVNTIIDNI
CCCEEEEHHHEEECCEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCC
DYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAYDGTQFIYSP
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCEEEECC
AFPAVVKNTAGAGDAFNGALASGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVL
CCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHH
HRIQGSHYKQTISTH
HHHCCCHHHHHHCCC
>Mature Secondary Structure
MKNNVCVIGSFNVDIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFIT
CCCCEEEEEECCHHHHHHCCCCCCCCHHHHHHHEEECCCCCCHHHHHHHHCCCCCEEEEE
KVGSDHFSDYAINFINSSKIHKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTIS
ECCCCCCCCCEEEECCCCHHHHHHHEECCCCCCCEEEEEEECCCCCCEEEEECCCCCEEC
PDEITIQKEAIVHSDIVLVQLETNYEALQQTIRLAQKNDIPVIINPAPYNDMVNTIIDNI
CCCEEEEHHHEEECCEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCC
DYITPNETEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAYDGTQFIYSP
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCEEEECC
AFPAVVKNTAGAGDAFNGALASGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVL
CCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHH
HRIQGSHYKQTISTH
HHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]