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The map label for this gene is yisY [H]

Identifier: 39546358

GI number: 39546358

Start: 3240644

End: 3241459

Strand: Reverse

Name: yisY [H]

Synonym: STM3079.S

Alternate gene names: 39546358

Gene position: 3241459-3240644 (Counterclockwise)

Preceding gene: 16766381

Following gene: 16766379

Centisome position: 66.73

GC content: 50.49

Gene sequence:

>816_bases
ATGGACAAAGATAAATTTGTGGAAGCGAATGGTATCAAAATTCATTACGTTGAAGAGGGCGAGGGGCCTCCGCTGCTGTT
GATTCACGGTGGTGGTCTGACGGCGAAAAGTTGGCAGGGATTAGCGAAAGAGGCATCTCGATATTTTCGCGTCATCATGC
CGGACAGTCGTGGACATGGATTAACCAATAACCCGCAAGGAACGTTTAGCTATGATCTGATGACGGAAGATATGGCGGCT
TTTGTTAAAGCGCTGAAGCTGGAAAAACCGCTGGTGATGGGTTACAGCGATGGCGGCATGGTCGTTCTGAAGTTAACCAG
CCGATACCCGGATCTAGCGCGCGCTGCTATCGTCGGCGGCGCAACGCATCGCTTTGCTACGACCCATTACATGCAGGGGA
TGGAAATTTTTTATGGTAAAGGAATGCCTCAGGGGCAATTGACGGATCGCGATCTGGATAAAATGGCTTCGGATGCGCCC
GGGATGGTTAAATTTTATCAGAACATGCATCATCCAGAGCAAAAAGACTACTGGCGCACGTTCCTCAAAGGTGTCTGGCC
AATGTGGACAACGCCCACATCGCTGGCGGAAGAAGAGGTGAAAAAAATCCACATTCCTGTGCTATTACTGGACGGCGACC
GGGATGAATTTTTCACCGTTGAAGAAGTTACCGAGCTGTACCGGCTGCTGCCTCAGGCGGAGATGACCCTCATTCCCGGT
AGCGGTCACGCCATTTTCCAGACGCCAGGAAAAACACCGCTGTTTTACGCATTAGTGCTTGAGTTTTTACAGCGGCAAAT
CCCTAAGGCCTCTTAA

Upstream 100 bases:

>100_bases
CACGGAAAGTGATTGGCGAGGTGTTATGAATCATATTTTTAAATTAGCATTTATTTTTATTATCAATATTATATTTTTAA
TAAATGCTTCAGCAACAACG

Downstream 100 bases:

>100_bases
CTGACCGCGATGGACGTATGAGCCTACTGATTTGCGCTGGATATATATTTTTTTCGGGCGTTGTCTACTGTACCTGGCTA
AACTGACTTCAATAATGCGG

Product: hydrolase/acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MDKDKFVEANGIKIHYVEEGEGPPLLLIHGGGLTAKSWQGLAKEASRYFRVIMPDSRGHGLTNNPQGTFSYDLMTEDMAA
FVKALKLEKPLVMGYSDGGMVVLKLTSRYPDLARAAIVGGATHRFATTHYMQGMEIFYGKGMPQGQLTDRDLDKMASDAP
GMVKFYQNMHHPEQKDYWRTFLKGVWPMWTTPTSLAEEEVKKIHIPVLLLDGDRDEFFTVEEVTELYRLLPQAEMTLIPG
SGHAIFQTPGKTPLFYALVLEFLQRQIPKAS

Sequences:

>Translated_271_residues
MDKDKFVEANGIKIHYVEEGEGPPLLLIHGGGLTAKSWQGLAKEASRYFRVIMPDSRGHGLTNNPQGTFSYDLMTEDMAA
FVKALKLEKPLVMGYSDGGMVVLKLTSRYPDLARAAIVGGATHRFATTHYMQGMEIFYGKGMPQGQLTDRDLDKMASDAP
GMVKFYQNMHHPEQKDYWRTFLKGVWPMWTTPTSLAEEEVKKIHIPVLLLDGDRDEFFTVEEVTELYRLLPQAEMTLIPG
SGHAIFQTPGKTPLFYALVLEFLQRQIPKAS
>Mature_271_residues
MDKDKFVEANGIKIHYVEEGEGPPLLLIHGGGLTAKSWQGLAKEASRYFRVIMPDSRGHGLTNNPQGTFSYDLMTEDMAA
FVKALKLEKPLVMGYSDGGMVVLKLTSRYPDLARAAIVGGATHRFATTHYMQGMEIFYGKGMPQGQLTDRDLDKMASDAP
GMVKFYQNMHHPEQKDYWRTFLKGVWPMWTTPTSLAEEEVKKIHIPVLLLDGDRDEFFTVEEVTELYRLLPQAEMTLIPG
SGHAIFQTPGKTPLFYALVLEFLQRQIPKAS

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI17562298, Length=126, Percent_Identity=30.1587301587302, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24649021, Length=282, Percent_Identity=24.468085106383, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 30503; Mature: 30503

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKDKFVEANGIKIHYVEEGEGPPLLLIHGGGLTAKSWQGLAKEASRYFRVIMPDSRGHG
CCCCCEEECCCEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCCCC
LTNNPQGTFSYDLMTEDMAAFVKALKLEKPLVMGYSDGGMVVLKLTSRYPDLARAAIVGG
CCCCCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHCC
ATHRFATTHYMQGMEIFYGKGMPQGQLTDRDLDKMASDAPGMVKFYQNMHHPEQKDYWRT
CHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
FLKGVWPMWTTPTSLAEEEVKKIHIPVLLLDGDRDEFFTVEEVTELYRLLPQAEMTLIPG
HHHHCCCCCCCCHHHHHHHHHEEEEEEEEEECCCCCEEEHHHHHHHHHHCCCCCEEEECC
SGHAIFQTPGKTPLFYALVLEFLQRQIPKAS
CCCEEEECCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDKDKFVEANGIKIHYVEEGEGPPLLLIHGGGLTAKSWQGLAKEASRYFRVIMPDSRGHG
CCCCCEEECCCEEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCCCC
LTNNPQGTFSYDLMTEDMAAFVKALKLEKPLVMGYSDGGMVVLKLTSRYPDLARAAIVGG
CCCCCCCCEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHCC
ATHRFATTHYMQGMEIFYGKGMPQGQLTDRDLDKMASDAPGMVKFYQNMHHPEQKDYWRT
CHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
FLKGVWPMWTTPTSLAEEEVKKIHIPVLLLDGDRDEFFTVEEVTELYRLLPQAEMTLIPG
HHHHCCCCCCCCHHHHHHHHHEEEEEEEEEECCCCCEEEHHHHHHHHHHCCCCCEEEECC
SGHAIFQTPGKTPLFYALVLEFLQRQIPKAS
CCCEEEECCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]