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The map label for this gene is muT4 [H]

Identifier: 38234902

GI number: 38234902

Start: 2472392

End: 2473264

Strand: Direct

Name: muT4 [H]

Synonym: DIP2369

Alternate gene names: 38234902

Gene position: 2472392-2473264 (Clockwise)

Preceding gene: 38234897

Following gene: 38234903

Centisome position: 99.35

GC content: 58.65

Gene sequence:

>873_bases
ATGACTGAAAACGAACGGGCTCATGCGGATCATGCTTCCGCGTCGCCACAGCGCACGCGCCGCCGTCGTGGCAAGCCGCG
CAGGCGTATGGATTCAGGCGCTTCTACTCAAGGTGGTGGCGCCTCAAAGTCTGCTGCGCCCAGTTCGAGCACTTCCGGTT
CCCGCGGGGAGCGCGGCAGCCGTGGGGATGATAAAGACAAGCAGAATAAGCACACGAGACGGAAACGCCGTCCGGCGCAC
CGTTCTACCCAGCGTGGCTCCCACGGTGGGGATTCGTCGAATTCCGGCTCGGGTATCAAGCGGCGTCGGCACACGGGCAA
TAAGAACCGTGGCAACCAGTCGCGCCGCCAGAACAATAGGTCCTCACGGATCACTACCCGCGATGAGACGTCGGCAGGCG
GTCTTGTTATCTCCGGCCTAGCGGAGGCCGTGGACGAGAACAACAACGTGGATCTCTCTCGTATCTACGTGGCACTGATT
GGCCGCTTGGATCGTCGTGGGCGATTGCTGTGGTCAATGCCGAAGGGCCATGTGGAGCCCGGCGAGGAGACTGCTGCCAC
CGCTGAGCGTGAGGTGTGGGAGGAAACCGGCATCCATGGTGAGGTGATTACGCAGCTGGGCACGATTGATTATTGGTTTG
TGTCTGAAGGGGTGCGTATTCACAAGACGGTGCATCATCATTTGTTGCGCTATGTGGATGGTTATCTCAACGATGAGGAT
CCTGAGGTGACGGAGGTTGCGTGGATTCCTGCGGATGAGTTGATTGAGCATTTTGCGTATGCGGATGAGCGTAAGTTGGC
GCGTATTGCCCATGATGTGCTTCCTGAGTATGCGATCAAGGAGAAGGAAGCAGGGAGGGTTACTCCACGGTGA

Upstream 100 bases:

>100_bases
ACCAGTGGCTTATTCCTTGGAGGTACAATCTTATGCAAATCTTGGCACAAATGTGGTTCGTAGATACCTTCTTTAGCGTG
AACGGGATACGATCAGCGGG

Downstream 100 bases:

>100_bases
TGTCCCGCAACCTTCGTTTGGCAACGAGCACAGTGAGTGTGGCTGCGGCGAGTGTGGTCGCGTTGGCTGCTCCGGTGGTG
GTGCCGGTTGTTTCTGCTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MTENERAHADHASASPQRTRRRRGKPRRRMDSGASTQGGGASKSAAPSSSTSGSRGERGSRGDDKDKQNKHTRRKRRPAH
RSTQRGSHGGDSSNSGSGIKRRRHTGNKNRGNQSRRQNNRSSRITTRDETSAGGLVISGLAEAVDENNNVDLSRIYVALI
GRLDRRGRLLWSMPKGHVEPGEETAATAEREVWEETGIHGEVITQLGTIDYWFVSEGVRIHKTVHHHLLRYVDGYLNDED
PEVTEVAWIPADELIEHFAYADERKLARIAHDVLPEYAIKEKEAGRVTPR

Sequences:

>Translated_290_residues
MTENERAHADHASASPQRTRRRRGKPRRRMDSGASTQGGGASKSAAPSSSTSGSRGERGSRGDDKDKQNKHTRRKRRPAH
RSTQRGSHGGDSSNSGSGIKRRRHTGNKNRGNQSRRQNNRSSRITTRDETSAGGLVISGLAEAVDENNNVDLSRIYVALI
GRLDRRGRLLWSMPKGHVEPGEETAATAEREVWEETGIHGEVITQLGTIDYWFVSEGVRIHKTVHHHLLRYVDGYLNDED
PEVTEVAWIPADELIEHFAYADERKLARIAHDVLPEYAIKEKEAGRVTPR
>Mature_289_residues
TENERAHADHASASPQRTRRRRGKPRRRMDSGASTQGGGASKSAAPSSSTSGSRGERGSRGDDKDKQNKHTRRKRRPAHR
STQRGSHGGDSSNSGSGIKRRRHTGNKNRGNQSRRQNNRSSRITTRDETSAGGLVISGLAEAVDENNNVDLSRIYVALIG
RLDRRGRLLWSMPKGHVEPGEETAATAEREVWEETGIHGEVITQLGTIDYWFVSEGVRIHKTVHHHLLRYVDGYLNDEDP
EVTEVAWIPADELIEHFAYADERKLARIAHDVLPEYAIKEKEAGRVTPR

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 32387; Mature: 32256

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENERAHADHASASPQRTRRRRGKPRRRMDSGASTQGGGASKSAAPSSSTSGSRGERGS
CCCCCCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGDDKDKQNKHTRRKRRPAHRSTQRGSHGGDSSNSGSGIKRRRHTGNKNRGNQSRRQNNR
CCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHCCC
SSRITTRDETSAGGLVISGLAEAVDENNNVDLSRIYVALIGRLDRRGRLLWSMPKGHVEP
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
GEETAATAEREVWEETGIHGEVITQLGTIDYWFVSEGVRIHKTVHHHLLRYVDGYLNDED
CHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
PEVTEVAWIPADELIEHFAYADERKLARIAHDVLPEYAIKEKEAGRVTPR
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TENERAHADHASASPQRTRRRRGKPRRRMDSGASTQGGGASKSAAPSSSTSGSRGERGS
CCCCCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGDDKDKQNKHTRRKRRPAHRSTQRGSHGGDSSNSGSGIKRRRHTGNKNRGNQSRRQNNR
CCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHCCC
SSRITTRDETSAGGLVISGLAEAVDENNNVDLSRIYVALIGRLDRRGRLLWSMPKGHVEP
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
GEETAATAEREVWEETGIHGEVITQLGTIDYWFVSEGVRIHKTVHHHLLRYVDGYLNDED
CHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
PEVTEVAWIPADELIEHFAYADERKLARIAHDVLPEYAIKEKEAGRVTPR
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]