Click here to switch to the map view.

The map label for this gene is ulaC [H]

Identifier: 38234866

GI number: 38234866

Start: 2438019

End: 2438813

Strand: Direct

Name: ulaC [H]

Synonym: DIP2332

Alternate gene names: 38234866

Gene position: 2438019-2438813 (Clockwise)

Preceding gene: 38234865

Following gene: 38234867

Centisome position: 97.97

GC content: 58.11

Gene sequence:

>795_bases
ATGAGTGCGCTCAATGAGCTTTTACACGATGATGCGATTGATCTGAACGCCCATGCCGAAACGTGGCAAGAGGCGATAGC
GCAAGCAGGCGCATTGTTGGAAAAGACTGGTGCGATTACCAGCGCTTACACAGAGTCTATGATTTCCTCGGTGGAGGAAC
AGGGCCCTTATATTGTTGTGGCCCCAGGGTTTGCGTTTGCGCATGCTCGCCCGTCAGAGGCGGTGAAGCGTACTGCGATT
GCGTGGACTCGGTTAGATTCGCCGGTGGAGTTCCATCATTCGAGTAATGATCCAGTGACTTTGGTGGTGGCGTTGGCGGC
GCAGGATGATCAGGCGCATACGGCTGCGATGCGGGAGATCGCCCAGGTGTTAGGGTCGCGTCGGCGGGATCTGGATACGG
TGGCGACTGTTGCTGAGTTGCGCGGTGTTTTGGAGGCGTCGAAACGCCGTAAGTCGCGTGGGGTTGCTGGGGGAGCGACG
CATGTGACAGCCCAAGATTCGGTGGAGTCGAAGGGCAAGATTTTGACGGTGTGTGGCAACGGGCTGGGCACGTCGTTGTT
CTTGAAGAACACTCTTGACCAAGTGTTGGATACGTGGGGTTGGGGGCCGTTTGTGTCCACGGAGGCCACGGACACGATTT
CTGCGAAGGGCCGCGCGAAGGAGGCGGACTTTCTGCTGACGTCTGAGGAGATCGCGCGCACGCTGGGCGATGTGGGTGTT
CCGGTGTATGTGATCAGCAATTTCACGTCGGAGGACGAGATCGACGCCGCCCTCCGCGAGCTTTACGACGTCTAA

Upstream 100 bases:

>100_bases
TTTGAGCAGATTTGGTGTGAAATAGTGCCCTGACGGGTGCAGTGTGCCCACCCCCGCCTATCCTCAGTAGTTGACACTAG
TTATCACTGAGGAGGGATAT

Downstream 100 bases:

>100_bases
TCGCCCAGTTGAGGAGCTTTTTATTATGAATGCACTCATTGCTATCCCAGAGTTTCTGGTTAATGAGATCTTGTCAGTGC
CGGCGTTTTTGATCGGCATC

Product: putative phosphotransferase system protein

Products: Protein Histidine; Sugar Phosphate. [C]

Alternate protein names: PTS system ascorbate-specific EIIA component [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSALNELLHDDAIDLNAHAETWQEAIAQAGALLEKTGAITSAYTESMISSVEEQGPYIVVAPGFAFAHARPSEAVKRTAI
AWTRLDSPVEFHHSSNDPVTLVVALAAQDDQAHTAAMREIAQVLGSRRRDLDTVATVAELRGVLEASKRRKSRGVAGGAT
HVTAQDSVESKGKILTVCGNGLGTSLFLKNTLDQVLDTWGWGPFVSTEATDTISAKGRAKEADFLLTSEEIARTLGDVGV
PVYVISNFTSEDEIDAALRELYDV

Sequences:

>Translated_264_residues
MSALNELLHDDAIDLNAHAETWQEAIAQAGALLEKTGAITSAYTESMISSVEEQGPYIVVAPGFAFAHARPSEAVKRTAI
AWTRLDSPVEFHHSSNDPVTLVVALAAQDDQAHTAAMREIAQVLGSRRRDLDTVATVAELRGVLEASKRRKSRGVAGGAT
HVTAQDSVESKGKILTVCGNGLGTSLFLKNTLDQVLDTWGWGPFVSTEATDTISAKGRAKEADFLLTSEEIARTLGDVGV
PVYVISNFTSEDEIDAALRELYDV
>Mature_263_residues
SALNELLHDDAIDLNAHAETWQEAIAQAGALLEKTGAITSAYTESMISSVEEQGPYIVVAPGFAFAHARPSEAVKRTAIA
WTRLDSPVEFHHSSNDPVTLVVALAAQDDQAHTAAMREIAQVLGSRRRDLDTVATVAELRGVLEASKRRKSRGVAGGATH
VTAQDSVESKGKILTVCGNGLGTSLFLKNTLDQVLDTWGWGPFVSTEATDTISAKGRAKEADFLLTSEEIARTLGDVGVP
VYVISNFTSEDEIDAALRELYDV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI2367359, Length=113, Percent_Identity=39.8230088495575, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790755, Length=111, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789302, Length=115, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178 [H]

Pfam domain/function: PF00359 PTS_EIIA_2 [H]

EC number: 2.7.1.69 [C]

Molecular weight: Translated: 28263; Mature: 28132

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALNELLHDDAIDLNAHAETWQEAIAQAGALLEKTGAITSAYTESMISSVEEQGPYIVV
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEE
APGFAFAHARPSEAVKRTAIAWTRLDSPVEFHHSSNDPVTLVVALAAQDDQAHTAAMREI
ECCCHHHCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEEEEECCCCHHHHHHHHHH
AQVLGSRRRDLDTVATVAELRGVLEASKRRKSRGVAGGATHVTAQDSVESKGKILTVCGN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECC
GLGTSLFLKNTLDQVLDTWGWGPFVSTEATDTISAKGRAKEADFLLTSEEIARTLGDVGV
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCHHEEEHHHHHHHHHHCCC
PVYVISNFTSEDEIDAALRELYDV
CEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SALNELLHDDAIDLNAHAETWQEAIAQAGALLEKTGAITSAYTESMISSVEEQGPYIVV
CHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEE
APGFAFAHARPSEAVKRTAIAWTRLDSPVEFHHSSNDPVTLVVALAAQDDQAHTAAMREI
ECCCHHHCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCEEEEEEEECCCCHHHHHHHHHH
AQVLGSRRRDLDTVATVAELRGVLEASKRRKSRGVAGGATHVTAQDSVESKGKILTVCGN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEECC
GLGTSLFLKNTLDQVLDTWGWGPFVSTEATDTISAKGRAKEADFLLTSEEIARTLGDVGV
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCHHEEEHHHHHHHHHHCCC
PVYVISNFTSEDEIDAALRELYDV
CEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Protein N-Phosphohistidine; Sugar [C]

Specific reaction: Protein N-Phosphohistidine + Sugar = Protein Histidine + Sugar Phosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]