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The map label for this gene is recG [H]

Identifier: 38234835

GI number: 38234835

Start: 2395856

End: 2397301

Strand: Reverse

Name: recG [H]

Synonym: DIP2300

Alternate gene names: 38234835

Gene position: 2397301-2395856 (Counterclockwise)

Preceding gene: 38234836

Following gene: 38234830

Centisome position: 96.33

GC content: 48.82

Gene sequence:

>1446_bases
ATGGGTGTAGTGAATCAGTCGGAGCTAGCGTCGATTATTAGGCGTTTAAGAGTTATCGGCACTGATGGCCAATCTGTGGA
AGTAAAAAGCGGCGTAGGTAAATCGGTCGTTGAGTCTTTGAGTGCTTTTGCCAATACCTCGGGCGGGATCATTATCGTAG
GTATTTCTGAGGAAGCAGGGTTTCTTCCTGTGCCGGATTTTGATGCAGCTAAGGCACATGACAAGTTAGTCTCGTTTTGT
GGTCAACTTACCCCTCCGATAAGGCCAACTATTGAAATTGTGGAATTCGAAGATTCTTCAGTCGTGGTTGCCGAGGTTGA
AGAGCTACTGCCGCGAGAAAAACCTTGTTTTATTACGGAACGGGGAAGTTTGCGAGGGTCGTATTACCGAGTCGGTGATG
CGGACATTCGTATGAGCACCTATGAGGTGGAGCGCTTTATAGAAGAACGGCAACAGCCGCGGTGGGATGAGGAAGCTGTA
GCCGGCTCAGGGCTAGTAGATCTTGATCAGAACATGCTGGATACCTATGTAGATCGTCAGCGCAGTGATCGTCCGCGTAC
TTTTGCGGACGGGCTTCCGACCGCTCTTCAGAGGCTGCGTGTTGTCGTAGAAGATAGTGTCAGTTTAGGCGCTTTACTTA
CCATGGGTACTGATCCTCAAGCGATATTCCCTCGGCTTACTGTCACTTTTGCTGTCTATCCCGGTGCTGACAAGGGAGAT
GTTTTGGATGGTATCCGGTTAGAAGAAAGCAAAACATTGTATGGGCCGATACCGGATTTAGTGCAGCAGACAGTGGACTT
GGTCAGACGTAATATGCGTACCGCAGCACTGATCGACGGTGCTTTCCGTACTGATCTCCCCGACTATCCGCTTGTTGCAG
TTCGTGAAGCCGTGGTTAATGCCTTGATGCACAGAGATTATTCACCGTTAGCTCGTGGTAGCCAGGTGCAGGTCAATATG
TTTGTTGATCGTTTGGAGATATCTAATCCGGGTGGTCTGTATGGCAATGTTACTGAGCAGAACATTCGAAAGCCCGGAAA
TAGTTCGACTAGGAATCAGCGTATTTCGCATTTTTTGGAAAGCACTGATTTTCCAGGTGGTGGTCTTGTAGCTGAAAATC
GTGGTACGGGGATTGCCGTTATTGATAAGTCTCTAGAACAGGCTCTCATGCCACCTGCTCAGATCATCAATCGGCTTGAT
TCTTTTACGATTGTTTTCCGCCGTCGGCGAGTTGCGGTAGCCGAAAAGCACCTTAGTTCTCATGATTTTGTTCAGTTCTA
TTTGGAAGAGCATGAAAGTGCTAGCACTTCAGAGCTCGTGGAAGCTTCCGGTTTTAGTCGCACGGCGATCCAGCGGGCTT
TGAATATGGGTATTGAGTCGGGTGAGATTGAAACCACGGAACCGAGACGTTCGCCGAAGCAGCGGTATCGGCTTCGTCGA
ACTTAA

Upstream 100 bases:

>100_bases
TAAAAGTGGCCTTCTAACTGCGGAAATAACTTAACACCCAACATAACACCTACTTCCCACATGTGTTATGTTGGGTGTTA
AGTTCTATGGGAGGTCGGCA

Downstream 100 bases:

>100_bases
CACCCAACATAACACCTACTTCCCACATGTGTTATGTTGGGTGTTAAGTTCACCTCTTGGTTGTGGTTAGTGTCCTATGA
TCGACATCTGGAATACAGTA

Product: putative DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MGVVNQSELASIIRRLRVIGTDGQSVEVKSGVGKSVVESLSAFANTSGGIIIVGISEEAGFLPVPDFDAAKAHDKLVSFC
GQLTPPIRPTIEIVEFEDSSVVVAEVEELLPREKPCFITERGSLRGSYYRVGDADIRMSTYEVERFIEERQQPRWDEEAV
AGSGLVDLDQNMLDTYVDRQRSDRPRTFADGLPTALQRLRVVVEDSVSLGALLTMGTDPQAIFPRLTVTFAVYPGADKGD
VLDGIRLEESKTLYGPIPDLVQQTVDLVRRNMRTAALIDGAFRTDLPDYPLVAVREAVVNALMHRDYSPLARGSQVQVNM
FVDRLEISNPGGLYGNVTEQNIRKPGNSSTRNQRISHFLESTDFPGGGLVAENRGTGIAVIDKSLEQALMPPAQIINRLD
SFTIVFRRRRVAVAEKHLSSHDFVQFYLEEHESASTSELVEASGFSRTAIQRALNMGIESGEIETTEPRRSPKQRYRLRR
T

Sequences:

>Translated_481_residues
MGVVNQSELASIIRRLRVIGTDGQSVEVKSGVGKSVVESLSAFANTSGGIIIVGISEEAGFLPVPDFDAAKAHDKLVSFC
GQLTPPIRPTIEIVEFEDSSVVVAEVEELLPREKPCFITERGSLRGSYYRVGDADIRMSTYEVERFIEERQQPRWDEEAV
AGSGLVDLDQNMLDTYVDRQRSDRPRTFADGLPTALQRLRVVVEDSVSLGALLTMGTDPQAIFPRLTVTFAVYPGADKGD
VLDGIRLEESKTLYGPIPDLVQQTVDLVRRNMRTAALIDGAFRTDLPDYPLVAVREAVVNALMHRDYSPLARGSQVQVNM
FVDRLEISNPGGLYGNVTEQNIRKPGNSSTRNQRISHFLESTDFPGGGLVAENRGTGIAVIDKSLEQALMPPAQIINRLD
SFTIVFRRRRVAVAEKHLSSHDFVQFYLEEHESASTSELVEASGFSRTAIQRALNMGIESGEIETTEPRRSPKQRYRLRR
T
>Mature_480_residues
GVVNQSELASIIRRLRVIGTDGQSVEVKSGVGKSVVESLSAFANTSGGIIIVGISEEAGFLPVPDFDAAKAHDKLVSFCG
QLTPPIRPTIEIVEFEDSSVVVAEVEELLPREKPCFITERGSLRGSYYRVGDADIRMSTYEVERFIEERQQPRWDEEAVA
GSGLVDLDQNMLDTYVDRQRSDRPRTFADGLPTALQRLRVVVEDSVSLGALLTMGTDPQAIFPRLTVTFAVYPGADKGDV
LDGIRLEESKTLYGPIPDLVQQTVDLVRRNMRTAALIDGAFRTDLPDYPLVAVREAVVNALMHRDYSPLARGSQVQVNMF
VDRLEISNPGGLYGNVTEQNIRKPGNSSTRNQRISHFLESTDFPGGGLVAENRGTGIAVIDKSLEQALMPPAQIINRLDS
FTIVFRRRRVAVAEKHLSSHDFVQFYLEEHESASTSELVEASGFSRTAIQRALNMGIESGEIETTEPRRSPKQRYRLRRT

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG2865

COG function: function code K; Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 53269; Mature: 53138

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVVNQSELASIIRRLRVIGTDGQSVEVKSGVGKSVVESLSAFANTSGGIIIVGISEEAG
CCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCC
FLPVPDFDAAKAHDKLVSFCGQLTPPIRPTIEIVEFEDSSVVVAEVEELLPREKPCFITE
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEC
RGSLRGSYYRVGDADIRMSTYEVERFIEERQQPRWDEEAVAGSGLVDLDQNMLDTYVDRQ
CCCCCCCEEEECCCCEEEHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
RSDRPRTFADGLPTALQRLRVVVEDSVSLGALLTMGTDPQAIFPRLTVTFAVYPGADKGD
CCCCCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHCCEEEEEEEEECCCCCCC
VLDGIRLEESKTLYGPIPDLVQQTVDLVRRNMRTAALIDGAFRTDLPDYPLVAVREAVVN
CCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCCCCHHHHHHHHHH
ALMHRDYSPLARGSQVQVNMFVDRLEISNPGGLYGNVTEQNIRKPGNSSTRNQRISHFLE
HHHHCCCCCCCCCCEEEEEEEEEEHEECCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHH
STDFPGGGLVAENRGTGIAVIDKSLEQALMPPAQIINRLDSFTIVFRRRRVAVAEKHLSS
HCCCCCCCEEECCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HDFVQFYLEEHESASTSELVEASGFSRTAIQRALNMGIESGEIETTEPRRSPKQRYRLRR
HHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCC
T
C
>Mature Secondary Structure 
GVVNQSELASIIRRLRVIGTDGQSVEVKSGVGKSVVESLSAFANTSGGIIIVGISEEAG
CCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCC
FLPVPDFDAAKAHDKLVSFCGQLTPPIRPTIEIVEFEDSSVVVAEVEELLPREKPCFITE
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEC
RGSLRGSYYRVGDADIRMSTYEVERFIEERQQPRWDEEAVAGSGLVDLDQNMLDTYVDRQ
CCCCCCCEEEECCCCEEEHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
RSDRPRTFADGLPTALQRLRVVVEDSVSLGALLTMGTDPQAIFPRLTVTFAVYPGADKGD
CCCCCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHCCEEEEEEEEECCCCCCC
VLDGIRLEESKTLYGPIPDLVQQTVDLVRRNMRTAALIDGAFRTDLPDYPLVAVREAVVN
CCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHCCCCCCCHHHHHHHHHH
ALMHRDYSPLARGSQVQVNMFVDRLEISNPGGLYGNVTEQNIRKPGNSSTRNQRISHFLE
HHHHCCCCCCCCCCEEEEEEEEEEHEECCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHH
STDFPGGGLVAENRGTGIAVIDKSLEQALMPPAQIINRLDSFTIVFRRRRVAVAEKHLSS
HCCCCCCCEEECCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HDFVQFYLEEHESASTSELVEASGFSRTAIQRALNMGIESGEIETTEPRRSPKQRYRLRR
HHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9603897 [H]