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The map label for this gene is ybbO [C]

Identifier: 38234833

GI number: 38234833

Start: 2394633

End: 2395304

Strand: Direct

Name: ybbO [C]

Synonym: DIP2298

Alternate gene names: 38234833

Gene position: 2394633-2395304 (Clockwise)

Preceding gene: 38234832

Following gene: 38234834

Centisome position: 96.22

GC content: 60.12

Gene sequence:

>672_bases
ATGGATCGCGTTGCAGTTGTCACTGGTGGAAGCAGGGGCGTGGGCCTCAGCGTGGTTCGCACCCTCCTCGAGGCTGGTTG
GCGCGTCCATGCCCACTATCGCACCCAGCCCGCCGACATCACCCACGATCGACTCACGTGGTGGCAGGCAGACTTCACTC
AGGGCCTTCCCACGGCACAGGCGAGTGGTTTTCCACAACTTCCGCGTATCGACGCCCTCATCCACTGCGCCGGCGTGGCC
ACTCTCGGCTCCTGCGCCAGTGTGGAGCGTGACGAATGGGAGCGCCACATGTCCGTTAACCTTCATAGCCCAGTGCAGCT
GACCCGTCAGCTTCTCCCCCAACTTCGGGCAAACCACGCTCACGTGGTGTACATCAATTCTGGTGCCGGTAAGCGAGCTA
ACCCACAGTGGGGAGCTTATGCGGCAAGCAAATTCGCCGCCCGCGCATGGTGCGATGCGCTGCGCCAAGAAGAGCCAGAG
ATCACCGTGACCTCGATCTTCCCAGGCCGGATCGCCACTGACATGCAAAAAGCCATCGTTGAGTACGAAGGCAATAGCTA
CAACCCTAAGAACTTCATTGCTCCCACCACTGTGGCTCACAGTGTTCTCCACAGCCTCAGCGTTGGTGCCGATGCCATCA
TCCCTGAGATTGTCATCCGACCGCGGATGTAA

Upstream 100 bases:

>100_bases
CCCAGGCCACCGAGATCCTCCCCTACGTCAGCGTGCCCGTGCTGATGATCCCCGCAACCACTAAGGTGGACAAAAAATCC
AAGAAGTAGAAGGGGAGCAC

Downstream 100 bases:

>100_bases
AATCAGTCACTATGCCCAAACATTTGGAGCACCCAGAAAACGACCTCCGCTCGGATGCTGACTCAGCGAACAGGTTGCGC
CCGCTCCCGCAATCCTTCGA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MDRVAVVTGGSRGVGLSVVRTLLEAGWRVHAHYRTQPADITHDRLTWWQADFTQGLPTAQASGFPQLPRIDALIHCAGVA
TLGSCASVERDEWERHMSVNLHSPVQLTRQLLPQLRANHAHVVYINSGAGKRANPQWGAYAASKFAARAWCDALRQEEPE
ITVTSIFPGRIATDMQKAIVEYEGNSYNPKNFIAPTTVAHSVLHSLSVGADAIIPEIVIRPRM

Sequences:

>Translated_223_residues
MDRVAVVTGGSRGVGLSVVRTLLEAGWRVHAHYRTQPADITHDRLTWWQADFTQGLPTAQASGFPQLPRIDALIHCAGVA
TLGSCASVERDEWERHMSVNLHSPVQLTRQLLPQLRANHAHVVYINSGAGKRANPQWGAYAASKFAARAWCDALRQEEPE
ITVTSIFPGRIATDMQKAIVEYEGNSYNPKNFIAPTTVAHSVLHSLSVGADAIIPEIVIRPRM
>Mature_223_residues
MDRVAVVTGGSRGVGLSVVRTLLEAGWRVHAHYRTQPADITHDRLTWWQADFTQGLPTAQASGFPQLPRIDALIHCAGVA
TLGSCASVERDEWERHMSVNLHSPVQLTRQLLPQLRANHAHVVYINSGAGKRANPQWGAYAASKFAARAWCDALRQEEPE
ITVTSIFPGRIATDMQKAIVEYEGNSYNPKNFIAPTTVAHSVLHSLSVGADAIIPEIVIRPRM

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=224, Percent_Identity=31.25, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5031737, Length=211, Percent_Identity=31.7535545023697, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1786701, Length=221, Percent_Identity=27.6018099547511, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787526, Length=218, Percent_Identity=28.4403669724771, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=195, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=184, Percent_Identity=27.1739130434783, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322226, Length=199, Percent_Identity=30.1507537688442, Blast_Score=82, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=27.3469387755102, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=204, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358495, Length=226, Percent_Identity=29.646017699115, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571526, Length=189, Percent_Identity=30.6878306878307, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651139, Length=108, Percent_Identity=36.1111111111111, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24504; Mature: 24504

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVAVVTGGSRGVGLSVVRTLLEAGWRVHAHYRTQPADITHDRLTWWQADFTQGLPTAQ
CCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHEEHHHHHCCCCCCC
ASGFPQLPRIDALIHCAGVATLGSCASVERDEWERHMSVNLHSPVQLTRQLLPQLRANHA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCE
HVVYINSGAGKRANPQWGAYAASKFAARAWCDALRQEEPEITVTSIFPGRIATDMQKAIV
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
EYEGNSYNPKNFIAPTTVAHSVLHSLSVGADAIIPEIVIRPRM
HHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MDRVAVVTGGSRGVGLSVVRTLLEAGWRVHAHYRTQPADITHDRLTWWQADFTQGLPTAQ
CCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHEEHHHHHCCCCCCC
ASGFPQLPRIDALIHCAGVATLGSCASVERDEWERHMSVNLHSPVQLTRQLLPQLRANHA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCE
HVVYINSGAGKRANPQWGAYAASKFAARAWCDALRQEEPEITVTSIFPGRIATDMQKAIV
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
EYEGNSYNPKNFIAPTTVAHSVLHSLSVGADAIIPEIVIRPRM
HHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA