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The map label for this gene is mmpL3 [H]

Identifier: 38234726

GI number: 38234726

Start: 2260129

End: 2262369

Strand: Direct

Name: mmpL3 [H]

Synonym: DIP2183

Alternate gene names: 38234726

Gene position: 2260129-2262369 (Clockwise)

Preceding gene: 38234725

Following gene: 38234727

Centisome position: 90.82

GC content: 58.68

Gene sequence:

>2241_bases
ATGTTCTCTCGCTGGGGAGACTTTTCATACCGCCACCGCAAGGTCGTACCTATCGTCATTGTGGCGCTGATCCTCGCCGT
ATACACGCTCTTCGGAGCACGCTTGGCGGATCGCATGAGCCAAGAAGGCTGGGAAGACCCCGGTTCTTCGTCCGCCCAAG
CCGCCGCGATTGAGCACGATACCTTCGGCCGCGATAACGACGGCGATGTGATTTTGCTCTTCACAGCGAAAGACGGCATC
GCGCACAGCCCAAGCTTTGACAAGATCAAGAAGTATCTCGACTCCTTGAAAACCGATCACAGCGACCACGTCGATGCCGT
CACCTCCTACTTTGACAAGCGCAACGCGCAACTCATCTCCAAGGACGGCACCACCGCCTTCGCGGCTGTCTCGCTGCGTG
GCGACGGCGAACAAACCCTCAAGGACTTCCGTGCCATCGAATCCGATCTGCACCCCCAGTTCCCAGAGGTCACCGTCCAG
GTAGCCGGATCCACCGCCGTGGCCGACGCCCTCGACAAGGGCATGTCCGGCGACATCAAACGCGCCGAGGTAGTAGCCCT
GCCCGTCGTCGCCGTGCTCCTGCTCATCGTCTTCGGCTCGGTAGTAGCCGCAGGCATGCCACTGATCGTAGGTATCCTCT
CCATCTTGGGATCCTTGGGTGTACTGTCCATCTTGGCAGGCTTTGTGCAGGTCAACGTGTTCGCACAGAGCGTGGTCACC
CTCCTAGGACTTGGCCTTGCTATCGACTACGGCCTGTTCATGGTGTCCCGCTTCCGTGAGGAGCTCGACGCCGGCAGACC
CATCCCCGATGCGGTACGCATCACCACCGCCACCGCCGGCAAAACGGTAACGTTCTCCGCAGCTATGGTCGCAGTGGCGC
TATCTGGGCTTTTGGTGTTCCCACAGGCCTTCCTCAAATCCGTCGCCTACGGTGCGATCAGCGCCGTGGGCCTAGCAGCA
CTGCTGTCCATCACCGTCCTGCCAGCGCTTTTTGGCATGCTGGGCAAAAACATCGACAAGTGGACGCTGCGCCGCACCTC
CCGCAAGGCTACGTCGTTACGCTCCACCGCGTGGTACCGCATTCCCGCATGGGCCATGAAGCACTCCGCGCTGGTCACCG
TCGGAATTGTTGCAGTACTACTGGGACTTACTTTGCCGCTTGCCGGCGTAAAGTTCGGCGGTATCAACGAAACATACCTG
CCGCCGAACAACACGGTGCGCACAGCACAAGCCTCCTTTGACGAGAACTTCCCGCACTTCCGCACCGAACCCATCAAGCT
CGTGATCACCGGCGCCACCAACCAACAGCTCGTCGACGTGTATCAGCAGGCCAACAAAGTTGAAGGCCTCACCGATCGTT
TCAAGCCCAGCTCGGCCACCAAGGACGGCACCACGGTCCTATCCGCCGGCATTGAAAACCGCGAGGACAACGCCAAGGTC
GTAGAACAGCTGCGAGCTATCGACGCTCCCGAGGGCGTATCCGTCTACATCGGCGGCATCCCAGCAATGGAAGTCGAATC
CATCGAAGCGCTCTTTGACAAGCTGCCATGGATGGCGATCTACATCGTCACTGCCACATTCTTGCTGATGTCGCTCGTAT
TCGGCTCCATGATCTTGCCAGCCAAGGCCATCATCATGACCATCCTAGGTTTGGGCTCCACCTTGGGAATCCTGACCGCC
ATGTTCGTTGACGGTGTTGGCTCCTCGCTGTTCAACTTCTCCGCCGGCCCACTGATGAGCCCCGTTCTCGTGCTCATCAT
GGCCATCGTCTACGGACTATCCACCGACTACGAGGTCTTCCTAGTCTCTCGCATGGTGGAAGCCCGCGCCAAAGGCGAAT
CCACCGACGAGGCCATCAAGTACGGCACCGCACACACCGGTGGCATCATCACCGCGGCAGCTTTAATCATGATCGTGGTC
TGCGGCGCCTTCGGGTTCTCTGAGATCGTGATGATGAAATACATCGCCTTTGGCATGGTCGTAGCATTGCTTTTCGACGC
CACCATCATCCGCATGATGCTCGTCCCAGCCGTTATGCATCTCCTGCGCGAAGACAACTGGTGGGGCCCCGCCTGGCTGA
AAAAGATGCAAGTCTCCGAGGGTGGTTCCACTGAACACGACCCGCTTCACCATCTCACCGTAGACTTGGATACAGCCGGA
CGATCCGGACGCACCGTTAAAGACGATGCCGAGCTAGTACCATTTTCCGAACTGATGAAACGACTGAGTGAAGAATCCTA
A

Upstream 100 bases:

>100_bases
GTGTTAGCCTCGACAACCTCCCCGAAGAGGGAGCCTGGCTCAAGCCCATCCGACCGCTCAGCGCTCTGCTTTCCAAGAGC
AAATAAGAGAGGAAACCCGT

Downstream 100 bases:

>100_bases
GATGCAGATCCTGAACAACAAGTGGGTGCGATTTCTGTTCCCCCTTGTTGTTCTGGTGATCGCAGCGTTTCTTCTTCGAA
ACAAAATGCCCTTCCTTGCA

Product: putative integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 746; Mature: 746

Protein sequence:

>746_residues
MFSRWGDFSYRHRKVVPIVIVALILAVYTLFGARLADRMSQEGWEDPGSSSAQAAAIEHDTFGRDNDGDVILLFTAKDGI
AHSPSFDKIKKYLDSLKTDHSDHVDAVTSYFDKRNAQLISKDGTTAFAAVSLRGDGEQTLKDFRAIESDLHPQFPEVTVQ
VAGSTAVADALDKGMSGDIKRAEVVALPVVAVLLLIVFGSVVAAGMPLIVGILSILGSLGVLSILAGFVQVNVFAQSVVT
LLGLGLAIDYGLFMVSRFREELDAGRPIPDAVRITTATAGKTVTFSAAMVAVALSGLLVFPQAFLKSVAYGAISAVGLAA
LLSITVLPALFGMLGKNIDKWTLRRTSRKATSLRSTAWYRIPAWAMKHSALVTVGIVAVLLGLTLPLAGVKFGGINETYL
PPNNTVRTAQASFDENFPHFRTEPIKLVITGATNQQLVDVYQQANKVEGLTDRFKPSSATKDGTTVLSAGIENREDNAKV
VEQLRAIDAPEGVSVYIGGIPAMEVESIEALFDKLPWMAIYIVTATFLLMSLVFGSMILPAKAIIMTILGLGSTLGILTA
MFVDGVGSSLFNFSAGPLMSPVLVLIMAIVYGLSTDYEVFLVSRMVEARAKGESTDEAIKYGTAHTGGIITAAALIMIVV
CGAFGFSEIVMMKYIAFGMVVALLFDATIIRMMLVPAVMHLLREDNWWGPAWLKKMQVSEGGSTEHDPLHHLTVDLDTAG
RSGRTVKDDAELVPFSELMKRLSEES

Sequences:

>Translated_746_residues
MFSRWGDFSYRHRKVVPIVIVALILAVYTLFGARLADRMSQEGWEDPGSSSAQAAAIEHDTFGRDNDGDVILLFTAKDGI
AHSPSFDKIKKYLDSLKTDHSDHVDAVTSYFDKRNAQLISKDGTTAFAAVSLRGDGEQTLKDFRAIESDLHPQFPEVTVQ
VAGSTAVADALDKGMSGDIKRAEVVALPVVAVLLLIVFGSVVAAGMPLIVGILSILGSLGVLSILAGFVQVNVFAQSVVT
LLGLGLAIDYGLFMVSRFREELDAGRPIPDAVRITTATAGKTVTFSAAMVAVALSGLLVFPQAFLKSVAYGAISAVGLAA
LLSITVLPALFGMLGKNIDKWTLRRTSRKATSLRSTAWYRIPAWAMKHSALVTVGIVAVLLGLTLPLAGVKFGGINETYL
PPNNTVRTAQASFDENFPHFRTEPIKLVITGATNQQLVDVYQQANKVEGLTDRFKPSSATKDGTTVLSAGIENREDNAKV
VEQLRAIDAPEGVSVYIGGIPAMEVESIEALFDKLPWMAIYIVTATFLLMSLVFGSMILPAKAIIMTILGLGSTLGILTA
MFVDGVGSSLFNFSAGPLMSPVLVLIMAIVYGLSTDYEVFLVSRMVEARAKGESTDEAIKYGTAHTGGIITAAALIMIVV
CGAFGFSEIVMMKYIAFGMVVALLFDATIIRMMLVPAVMHLLREDNWWGPAWLKKMQVSEGGSTEHDPLHHLTVDLDTAG
RSGRTVKDDAELVPFSELMKRLSEES
>Mature_746_residues
MFSRWGDFSYRHRKVVPIVIVALILAVYTLFGARLADRMSQEGWEDPGSSSAQAAAIEHDTFGRDNDGDVILLFTAKDGI
AHSPSFDKIKKYLDSLKTDHSDHVDAVTSYFDKRNAQLISKDGTTAFAAVSLRGDGEQTLKDFRAIESDLHPQFPEVTVQ
VAGSTAVADALDKGMSGDIKRAEVVALPVVAVLLLIVFGSVVAAGMPLIVGILSILGSLGVLSILAGFVQVNVFAQSVVT
LLGLGLAIDYGLFMVSRFREELDAGRPIPDAVRITTATAGKTVTFSAAMVAVALSGLLVFPQAFLKSVAYGAISAVGLAA
LLSITVLPALFGMLGKNIDKWTLRRTSRKATSLRSTAWYRIPAWAMKHSALVTVGIVAVLLGLTLPLAGVKFGGINETYL
PPNNTVRTAQASFDENFPHFRTEPIKLVITGATNQQLVDVYQQANKVEGLTDRFKPSSATKDGTTVLSAGIENREDNAKV
VEQLRAIDAPEGVSVYIGGIPAMEVESIEALFDKLPWMAIYIVTATFLLMSLVFGSMILPAKAIIMTILGLGSTLGILTA
MFVDGVGSSLFNFSAGPLMSPVLVLIMAIVYGLSTDYEVFLVSRMVEARAKGESTDEAIKYGTAHTGGIITAAALIMIVV
CGAFGFSEIVMMKYIAFGMVVALLFDATIIRMMLVPAVMHLLREDNWWGPAWLKKMQVSEGGSTEHDPLHHLTVDLDTAG
RSGRTVKDDAELVPFSELMKRLSEES

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 80108; Mature: 80108

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSRWGDFSYRHRKVVPIVIVALILAVYTLFGARLADRMSQEGWEDPGSSSAQAAAIEHD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEECC
TFGRDNDGDVILLFTAKDGIAHSPSFDKIKKYLDSLKTDHSDHVDAVTSYFDKRNAQLIS
CCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEE
KDGTTAFAAVSLRGDGEQTLKDFRAIESDLHPQFPEVTVQVAGSTAVADALDKGMSGDIK
CCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCCCCCC
RAEVVALPVVAVLLLIVFGSVVAAGMPLIVGILSILGSLGVLSILAGFVQVNVFAQSVVT
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGLGLAIDYGLFMVSRFREELDAGRPIPDAVRITTATAGKTVTFSAAMVAVALSGLLVF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHH
PQAFLKSVAYGAISAVGLAALLSITVLPALFGMLGKNIDKWTLRRTSRKATSLRSTAWYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEEE
IPAWAMKHSALVTVGIVAVLLGLTLPLAGVKFGGINETYLPPNNTVRTAQASFDENFPHF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCEEHHHHHHCCCCCCC
RTEPIKLVITGATNQQLVDVYQQANKVEGLTDRFKPSSATKDGTTVLSAGIENREDNAKV
CCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHH
VEQLRAIDAPEGVSVYIGGIPAMEVESIEALFDKLPWMAIYIVTATFLLMSLVFGSMILP
HHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AKAIIMTILGLGSTLGILTAMFVDGVGSSLFNFSAGPLMSPVLVLIMAIVYGLSTDYEVF
HHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
LVSRMVEARAKGESTDEAIKYGTAHTGGIITAAALIMIVVCGAFGFSEIVMMKYIAFGMV
HHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VALLFDATIIRMMLVPAVMHLLREDNWWGPAWLKKMQVSEGGSTEHDPLHHLTVDLDTAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECCC
RSGRTVKDDAELVPFSELMKRLSEES
CCCCCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MFSRWGDFSYRHRKVVPIVIVALILAVYTLFGARLADRMSQEGWEDPGSSSAQAAAIEHD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEECC
TFGRDNDGDVILLFTAKDGIAHSPSFDKIKKYLDSLKTDHSDHVDAVTSYFDKRNAQLIS
CCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEE
KDGTTAFAAVSLRGDGEQTLKDFRAIESDLHPQFPEVTVQVAGSTAVADALDKGMSGDIK
CCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCCCCCC
RAEVVALPVVAVLLLIVFGSVVAAGMPLIVGILSILGSLGVLSILAGFVQVNVFAQSVVT
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGLGLAIDYGLFMVSRFREELDAGRPIPDAVRITTATAGKTVTFSAAMVAVALSGLLVF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHHHH
PQAFLKSVAYGAISAVGLAALLSITVLPALFGMLGKNIDKWTLRRTSRKATSLRSTAWYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEEE
IPAWAMKHSALVTVGIVAVLLGLTLPLAGVKFGGINETYLPPNNTVRTAQASFDENFPHF
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCEEHHHHHHCCCCCCC
RTEPIKLVITGATNQQLVDVYQQANKVEGLTDRFKPSSATKDGTTVLSAGIENREDNAKV
CCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHH
VEQLRAIDAPEGVSVYIGGIPAMEVESIEALFDKLPWMAIYIVTATFLLMSLVFGSMILP
HHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AKAIIMTILGLGSTLGILTAMFVDGVGSSLFNFSAGPLMSPVLVLIMAIVYGLSTDYEVF
HHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
LVSRMVEARAKGESTDEAIKYGTAHTGGIITAAALIMIVVCGAFGFSEIVMMKYIAFGMV
HHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VALLFDATIIRMMLVPAVMHLLREDNWWGPAWLKKMQVSEGGSTEHDPLHHLTVDLDTAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECCC
RSGRTVKDDAELVPFSELMKRLSEES
CCCCCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]