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The map label for this gene is gldA [H]

Identifier: 38234463

GI number: 38234463

Start: 1942871

End: 1943947

Strand: Reverse

Name: gldA [H]

Synonym: DIP1893

Alternate gene names: 38234463

Gene position: 1943947-1942871 (Counterclockwise)

Preceding gene: 38234464

Following gene: 38234462

Centisome position: 78.11

GC content: 53.3

Gene sequence:

>1077_bases
ATGCCTTACTCTTTGCATTTACCGGGATATAGCATCGGCGATAACGCTTACGAAAAGATTGACGCGATCGTGTCGACCTA
TGGCTCGTCGGTGGCCGTGATTGGTGGCAAGACTGCTCTAGAAAAGTCGCGCCCGCGTCTCGAGGCCGCATTGGCTCATA
GCGGAATTGAAGTCGTGGACTGGATTGTTTATGGACATAACTGCACCTATGAGCGTGTCGACGCTCTGTGTGGTATGCCT
ACAGTGCAGCAAGCCGACATGATCTTTGGCGTCGGCGGCGGTCGTGCCGTCGATACGGTAAAGGTGGTTGCGAACCGTCT
GGGCAAGCCATTATTTGCATTTCCTACGTTGGGTTCGAACTGTGCCGCGGCAACGAATTTGTCTGTGGTGTACAAGGATG
ATGATTCCCTTGCCGGCTATGACTTCCAGCGCGGGCCGTGCCACCACGTGTTTATTGATACGACGGTGATCGCACAGTCG
CCTGCGGAGTTGTTGTGGGCTGGAATTGCAGATGGCATGTCTAAGGAGTGCGAGGTAAAGCTGCAGTCGCGGGGCCGCAA
TTTGTCGCATGCGCCTTTGATGGGTCGAAACGTGTGTTCGGCGGTAACACCTGCACTGATGGATTTTGGATTGCAGGCGT
TGGAGGATTGTCGTGCGGGTAGGTCGTCGCAGGCAATCGAGGAAGTCGCGTTAGCGATCATTATGACCTGTGGTTACGTG
TCTAACATGGCGGTGGATCCAGGGCAGGCGTATTACTACAATTCTTCGCTTGCGCATGCTTTTTATAACTCGTCGACGGC
ATTTCCGGAGTGCGTCGGCAAGCATCTGCATGGCGAGATTGTCTCTTATGGTGTGCTGGCGTTGTTGCAGTATGACGGCG
ACATGGAGACTAAGCGTCGTTATGTTGAGTTTTATAAGCAGATGGGATTCCCGTTGACGCTGGCGGATCTGGACTTACAA
GAATCGGATATTCCGGAGTTGGTGTCCCATGTGCCAGCGACCACGGAGTGGAAGACGGGGGATTTTGATCTTGAGCGTTT
TGCGCAAGCGATTATCGACGCTCAGGTATTTGCTTAA

Upstream 100 bases:

>100_bases
GATGGCGGAAGCGTGGGTGTCGCGCGTATGATGGTCGATTAATTCCATGTCCACTAGGTGGGATTTATTGTTTCATTTAC
GGCTTACTCAAGGTGGTTTT

Downstream 100 bases:

>100_bases
TGGTTTTTATCCTAAGAAATCCGTGTTGACCTTTGGATTTGTGGGTGTGAACATTATCTGTGTAAAGTAATGGCTCGTGC
AAGGGAAGGAAGTGATTCTC

Product: hypothetical protein

Products: NA

Alternate protein names: GDH; GLDH [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MPYSLHLPGYSIGDNAYEKIDAIVSTYGSSVAVIGGKTALEKSRPRLEAALAHSGIEVVDWIVYGHNCTYERVDALCGMP
TVQQADMIFGVGGGRAVDTVKVVANRLGKPLFAFPTLGSNCAAATNLSVVYKDDDSLAGYDFQRGPCHHVFIDTTVIAQS
PAELLWAGIADGMSKECEVKLQSRGRNLSHAPLMGRNVCSAVTPALMDFGLQALEDCRAGRSSQAIEEVALAIIMTCGYV
SNMAVDPGQAYYYNSSLAHAFYNSSTAFPECVGKHLHGEIVSYGVLALLQYDGDMETKRRYVEFYKQMGFPLTLADLDLQ
ESDIPELVSHVPATTEWKTGDFDLERFAQAIIDAQVFA

Sequences:

>Translated_358_residues
MPYSLHLPGYSIGDNAYEKIDAIVSTYGSSVAVIGGKTALEKSRPRLEAALAHSGIEVVDWIVYGHNCTYERVDALCGMP
TVQQADMIFGVGGGRAVDTVKVVANRLGKPLFAFPTLGSNCAAATNLSVVYKDDDSLAGYDFQRGPCHHVFIDTTVIAQS
PAELLWAGIADGMSKECEVKLQSRGRNLSHAPLMGRNVCSAVTPALMDFGLQALEDCRAGRSSQAIEEVALAIIMTCGYV
SNMAVDPGQAYYYNSSLAHAFYNSSTAFPECVGKHLHGEIVSYGVLALLQYDGDMETKRRYVEFYKQMGFPLTLADLDLQ
ESDIPELVSHVPATTEWKTGDFDLERFAQAIIDAQVFA
>Mature_357_residues
PYSLHLPGYSIGDNAYEKIDAIVSTYGSSVAVIGGKTALEKSRPRLEAALAHSGIEVVDWIVYGHNCTYERVDALCGMPT
VQQADMIFGVGGGRAVDTVKVVANRLGKPLFAFPTLGSNCAAATNLSVVYKDDDSLAGYDFQRGPCHHVFIDTTVIAQSP
AELLWAGIADGMSKECEVKLQSRGRNLSHAPLMGRNVCSAVTPALMDFGLQALEDCRAGRSSQAIEEVALAIIMTCGYVS
NMAVDPGQAYYYNSSLAHAFYNSSTAFPECVGKHLHGEIVSYGVLALLQYDGDMETKRRYVEFYKQMGFPLTLADLDLQE
SDIPELVSHVPATTEWKTGDFDLERFAQAIIDAQVFA

Specific function: Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions [H]

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082352, Length=331, Percent_Identity=27.7945619335347, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786815, Length=301, Percent_Identity=29.2358803986711, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016205 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.6 [H]

Molecular weight: Translated: 38820; Mature: 38689

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYSLHLPGYSIGDNAYEKIDAIVSTYGSSVAVIGGKTALEKSRPRLEAALAHSGIEVVD
CCEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHCCHHHHHHHHHCCHHEEE
WIVYGHNCTYERVDALCGMPTVQQADMIFGVGGGRAVDTVKVVANRLGKPLFAFPTLGSN
EEEECCCCCHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCC
CAAATNLSVVYKDDDSLAGYDFQRGPCHHVFIDTTVIAQSPAELLWAGIADGMSKECEVK
CCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHCCCCCHHEEE
LQSRGRNLSHAPLMGRNVCSAVTPALMDFGLQALEDCRAGRSSQAIEEVALAIIMTCGYV
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SNMAVDPGQAYYYNSSLAHAFYNSSTAFPECVGKHLHGEIVSYGVLALLQYDGDMETKRR
HCCCCCCCCEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YVEFYKQMGFPLTLADLDLQESDIPELVSHVPATTEWKTGDFDLERFAQAIIDAQVFA
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PYSLHLPGYSIGDNAYEKIDAIVSTYGSSVAVIGGKTALEKSRPRLEAALAHSGIEVVD
CEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHCCHHHHHHHHHCCHHEEE
WIVYGHNCTYERVDALCGMPTVQQADMIFGVGGGRAVDTVKVVANRLGKPLFAFPTLGSN
EEEECCCCCHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCC
CAAATNLSVVYKDDDSLAGYDFQRGPCHHVFIDTTVIAQSPAELLWAGIADGMSKECEVK
CCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHCCCCCHHEEE
LQSRGRNLSHAPLMGRNVCSAVTPALMDFGLQALEDCRAGRSSQAIEEVALAIIMTCGYV
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SNMAVDPGQAYYYNSSLAHAFYNSSTAFPECVGKHLHGEIVSYGVLALLQYDGDMETKRR
HCCCCCCCCEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YVEFYKQMGFPLTLADLDLQESDIPELVSHVPATTEWKTGDFDLERFAQAIIDAQVFA
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]