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The map label for this gene is dinG [H]

Identifier: 38234429

GI number: 38234429

Start: 1901706

End: 1903655

Strand: Direct

Name: dinG [H]

Synonym: DIP1859

Alternate gene names: 38234429

Gene position: 1901706-1903655 (Clockwise)

Preceding gene: 38234428

Following gene: 38234430

Centisome position: 76.42

GC content: 53.95

Gene sequence:

>1950_bases
TTGGTAGTTTCCACTGACGAACTTCTCAGTGCAGCTGTTGCTGCATTGGGAGGTTCTACGCGTAAAGGCCAAGTTTCGAT
GGCCAACGCGGTGACCAACGCTTTGGAAACGGAACGCCACTTGGCTGTTCAAGCTGGGACCGGCACGGGCAAGTCGCTTG
CTTATTTGGTTCCGGCAATTCGGCATGCTCAAGCCACCAACACCACAGTCGTTGTTTCTACAGCAACGATTGCCTTGCAA
CGCCAGCTCGTTGACCGCGATCTGCCACGTCTGGCGGACGCTTTGGAGCCTTTGTTGGAGCGTCGCCCAACCTTTGCCAT
CATGAAGGGTCGTGCGAACTATCTTTGCATGAACAAAATTGCAGCAGTTGAAGGCCCAGAAGATGCTCTGATTGATGAAG
AAGACATCTCGTGGTTGGGAAAGCACGTTGCTCGTATCCACGAATGGGCCAATGACACCGAAACCGGTGATCGCGATAGC
CTCGAACCGGGTGTTCCTGATTTGGCGTGGCGCCAAGTCAGTGTTTCTGCTCAAGAATGTATTGGTGCTTCGCGTTGCCC
TCATGGTGAAGACTGTTTTGCGGAACGAGCCCGCAAAAAGGCACATGAGGTAGATGTGATCGTAACCAACCACGCATTGC
TGGCGATTGATGCTTTGTCCGAGGTCAATGTATTGCCCGAGCATGATGTTGTGATCGTGGATGAGGCTCATGAGCTCGAC
GGCCGAATCACAGCAGTGGCAACCAATGAAATCGGTGTGACAGCGTTGTCGATGTCTGCACGACGCGCCGGCAAACTCGG
TGCTAATGGCAAAGACGAAAAAGTCGTTGACATCGCTAAAGAGTGGGAAGACGAGATGTTGACCATTGAGTCTGGTCGCA
TTACTGATCTTCCCGATTCGTTGCGGTCCCAGCTGGTATCCCTTCGCGACGCTTTGTGGTCCCTGCGCGATCAAGTCAGC
CACGCTCCCGACGGCGAGGCCGCAAACGATCCTGAACGGCATGCCGAACGCATGTCCCTGTCTAATCACCTGAACGACCA
GCATGATTCCGTCGTCCGTATTTTGGAGGTGTTCGAAGCCGAAGACCCCAGCACTCACGATGACGTAGTGTGGGTCATCC
ACGATGAGCGTCGAGGCGTCATGCTCAAAGTCGCCCCACTGTCGGTCGCCGGTTTGCTGCATACGCGCCTTTTCGGTGAA
AACACTGTGGTCTTGGCCTCGGCTACGTTGACCATCGGCGGTAATTTCAATGCCATGGCTGCTAGCTGGGGTTTGCCTAA
AGGAACATGGGATTCCCTCGATGCCGGTACGCCTTTTGATCCAGCAAAGTCGGGCATTTTGTACACGGCGCGCCATCTCC
CCGATCCAGGGCGTGATGGGCTGTCTCCGGAAACACTCGACGAAATCTACAATCTGATTATGGCGGCGGGCGGGCGCACT
TTGGGATTGTTTTCTTCTAAACGCGCAGCTGTTCAAGCTACCGAAGAGATGCGCAAGCGCTTGCCTTTCGATGTCCTGTG
CCAAGGCGATGACTCGACGGGGGCCTTGGTATCGCAGTTCTCCAAACAGGAAAACACCTGTTTGTTTGGCACATTGAGCC
TCTGGCAGGGAGTAGATGTTCCTGGTAAATCGTGTTCCTTGGTGATTATCGACAGAATTCCATTTCCACGCCCTGATGAT
CCGCTGTTGCAAGCCCGAAAGGAAGCAGCTGATGCCGATGGCCGTAACGGTTTCATGGAAGTTGCTGCTACGCATGCGGC
GTTGCTCATGGCACAAGGTGCTGGCCGTTTGCTGCGCCACGTCACTGACCGCGGAGTCGTCGCAATTTTGGATACCCGCA
TTGTAAAGAAGCGTTACGGTTCTTTCTTCTTGTCCTCTCTGCCTGCTTTTTGGCGCACAACAGATTCTTCTGTAGTCCAA
GGCGCTTTGAAACGATTGGTGCAAAAGTAA

Upstream 100 bases:

>100_bases
AGCCGAGACGAACCTGTCTTGGCAACGCGCCATGTGGGATTCGATCAGTAACTTTTAGCTGCCACGCCGTACCATATTCG
GCATGAGCTCCGTTTCCCCA

Downstream 100 bases:

>100_bases
AATGTGGCCAACACACGACCTTCCCATTCTGAGTAACAAGTCGCTTATCTTGCGAAAACTCCAGATCGAAGACACACCTC
GTTTAGTTGAGCTGGCCCAA

Product: DeaD/DeaH family helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MVVSTDELLSAAVAALGGSTRKGQVSMANAVTNALETERHLAVQAGTGTGKSLAYLVPAIRHAQATNTTVVVSTATIALQ
RQLVDRDLPRLADALEPLLERRPTFAIMKGRANYLCMNKIAAVEGPEDALIDEEDISWLGKHVARIHEWANDTETGDRDS
LEPGVPDLAWRQVSVSAQECIGASRCPHGEDCFAERARKKAHEVDVIVTNHALLAIDALSEVNVLPEHDVVIVDEAHELD
GRITAVATNEIGVTALSMSARRAGKLGANGKDEKVVDIAKEWEDEMLTIESGRITDLPDSLRSQLVSLRDALWSLRDQVS
HAPDGEAANDPERHAERMSLSNHLNDQHDSVVRILEVFEAEDPSTHDDVVWVIHDERRGVMLKVAPLSVAGLLHTRLFGE
NTVVLASATLTIGGNFNAMAASWGLPKGTWDSLDAGTPFDPAKSGILYTARHLPDPGRDGLSPETLDEIYNLIMAAGGRT
LGLFSSKRAAVQATEEMRKRLPFDVLCQGDDSTGALVSQFSKQENTCLFGTLSLWQGVDVPGKSCSLVIIDRIPFPRPDD
PLLQARKEAADADGRNGFMEVAATHAALLMAQGAGRLLRHVTDRGVVAILDTRIVKKRYGSFFLSSLPAFWRTTDSSVVQ
GALKRLVQK

Sequences:

>Translated_649_residues
MVVSTDELLSAAVAALGGSTRKGQVSMANAVTNALETERHLAVQAGTGTGKSLAYLVPAIRHAQATNTTVVVSTATIALQ
RQLVDRDLPRLADALEPLLERRPTFAIMKGRANYLCMNKIAAVEGPEDALIDEEDISWLGKHVARIHEWANDTETGDRDS
LEPGVPDLAWRQVSVSAQECIGASRCPHGEDCFAERARKKAHEVDVIVTNHALLAIDALSEVNVLPEHDVVIVDEAHELD
GRITAVATNEIGVTALSMSARRAGKLGANGKDEKVVDIAKEWEDEMLTIESGRITDLPDSLRSQLVSLRDALWSLRDQVS
HAPDGEAANDPERHAERMSLSNHLNDQHDSVVRILEVFEAEDPSTHDDVVWVIHDERRGVMLKVAPLSVAGLLHTRLFGE
NTVVLASATLTIGGNFNAMAASWGLPKGTWDSLDAGTPFDPAKSGILYTARHLPDPGRDGLSPETLDEIYNLIMAAGGRT
LGLFSSKRAAVQATEEMRKRLPFDVLCQGDDSTGALVSQFSKQENTCLFGTLSLWQGVDVPGKSCSLVIIDRIPFPRPDD
PLLQARKEAADADGRNGFMEVAATHAALLMAQGAGRLLRHVTDRGVVAILDTRIVKKRYGSFFLSSLPAFWRTTDSSVVQ
GALKRLVQK
>Mature_649_residues
MVVSTDELLSAAVAALGGSTRKGQVSMANAVTNALETERHLAVQAGTGTGKSLAYLVPAIRHAQATNTTVVVSTATIALQ
RQLVDRDLPRLADALEPLLERRPTFAIMKGRANYLCMNKIAAVEGPEDALIDEEDISWLGKHVARIHEWANDTETGDRDS
LEPGVPDLAWRQVSVSAQECIGASRCPHGEDCFAERARKKAHEVDVIVTNHALLAIDALSEVNVLPEHDVVIVDEAHELD
GRITAVATNEIGVTALSMSARRAGKLGANGKDEKVVDIAKEWEDEMLTIESGRITDLPDSLRSQLVSLRDALWSLRDQVS
HAPDGEAANDPERHAERMSLSNHLNDQHDSVVRILEVFEAEDPSTHDDVVWVIHDERRGVMLKVAPLSVAGLLHTRLFGE
NTVVLASATLTIGGNFNAMAASWGLPKGTWDSLDAGTPFDPAKSGILYTARHLPDPGRDGLSPETLDEIYNLIMAAGGRT
LGLFSSKRAAVQATEEMRKRLPFDVLCQGDDSTGALVSQFSKQENTCLFGTLSLWQGVDVPGKSCSLVIIDRIPFPRPDD
PLLQARKEAADADGRNGFMEVAATHAALLMAQGAGRLLRHVTDRGVVAILDTRIVKKRYGSFFLSSLPAFWRTTDSSVVQ
GALKRLVQK

Specific function: Probable helicase involved in DNA repair and perhaps also replication [H]

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788110, Length=657, Percent_Identity=31.9634703196347, Blast_Score=271, Evalue=1e-73,
Organism=Escherichia coli, GI1787018, Length=222, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014013
- InterPro:   IPR006555 [H]

Pfam domain/function: PF00270 DEAD [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 70329; Mature: 70329

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVSTDELLSAAVAALGGSTRKGQVSMANAVTNALETERHLAVQAGTGTGKSLAYLVPAI
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHH
RHAQATNTTVVVSTATIALQRQLVDRDLPRLADALEPLLERRPTFAIMKGRANYLCMNKI
HHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHH
AAVEGPEDALIDEEDISWLGKHVARIHEWANDTETGDRDSLEPGVPDLAWRQVSVSAQEC
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHH
IGASRCPHGEDCFAERARKKAHEVDVIVTNHALLAIDALSEVNVLPEHDVVIVDEAHELD
CCCCCCCCCHHHHHHHHHHHHHCEEEEEECCEEEEEEHHHHCCCCCCCCEEEEECCCCCC
GRITAVATNEIGVTALSMSARRAGKLGANGKDEKVVDIAKEWEDEMLTIESGRITDLPDS
CEEEEEEECCCCEEEEHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCHH
LRSQLVSLRDALWSLRDQVSHAPDGEAANDPERHAERMSLSNHLNDQHDSVVRILEVFEA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
EDPSTHDDVVWVIHDERRGVMLKVAPLSVAGLLHTRLFGENTVVLASATLTIGGNFNAMA
CCCCCCCCEEEEEEECCCCEEEEEECHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEE
ASWGLPKGTWDSLDAGTPFDPAKSGILYTARHLPDPGRDGLSPETLDEIYNLIMAAGGRT
ECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCE
LGLFSSKRAAVQATEEMRKRLPFDVLCQGDDSTGALVSQFSKQENTCLFGTLSLWQGVDV
EECCCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEHHHHCCCCC
PGKSCSLVIIDRIPFPRPDDPLLQARKEAADADGRNGFMEVAATHAALLMAQGAGRLLRH
CCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VTDRGVVAILDTRIVKKRYGSFFLSSLPAFWRTTDSSVVQGALKRLVQK
HHCCCEEEEHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVSTDELLSAAVAALGGSTRKGQVSMANAVTNALETERHLAVQAGTGTGKSLAYLVPAI
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHH
RHAQATNTTVVVSTATIALQRQLVDRDLPRLADALEPLLERRPTFAIMKGRANYLCMNKI
HHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHH
AAVEGPEDALIDEEDISWLGKHVARIHEWANDTETGDRDSLEPGVPDLAWRQVSVSAQEC
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHH
IGASRCPHGEDCFAERARKKAHEVDVIVTNHALLAIDALSEVNVLPEHDVVIVDEAHELD
CCCCCCCCCHHHHHHHHHHHHHCEEEEEECCEEEEEEHHHHCCCCCCCCEEEEECCCCCC
GRITAVATNEIGVTALSMSARRAGKLGANGKDEKVVDIAKEWEDEMLTIESGRITDLPDS
CEEEEEEECCCCEEEEHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCHH
LRSQLVSLRDALWSLRDQVSHAPDGEAANDPERHAERMSLSNHLNDQHDSVVRILEVFEA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
EDPSTHDDVVWVIHDERRGVMLKVAPLSVAGLLHTRLFGENTVVLASATLTIGGNFNAMA
CCCCCCCCEEEEEEECCCCEEEEEECHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEE
ASWGLPKGTWDSLDAGTPFDPAKSGILYTARHLPDPGRDGLSPETLDEIYNLIMAAGGRT
ECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCE
LGLFSSKRAAVQATEEMRKRLPFDVLCQGDDSTGALVSQFSKQENTCLFGTLSLWQGVDV
EECCCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEHHHHCCCCC
PGKSCSLVIIDRIPFPRPDDPLLQARKEAADADGRNGFMEVAATHAALLMAQGAGRLLRH
CCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VTDRGVVAILDTRIVKKRYGSFFLSSLPAFWRTTDSSVVQGALKRLVQK
HHCCCEEEEHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]