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The map label for this gene is yggV [C]

Identifier: 38234420

GI number: 38234420

Start: 1894916

End: 1895539

Strand: Reverse

Name: yggV [C]

Synonym: DIP1850

Alternate gene names: 38234420

Gene position: 1895539-1894916 (Counterclockwise)

Preceding gene: 38234421

Following gene: 38234417

Centisome position: 76.17

GC content: 59.78

Gene sequence:

>624_bases
GTGAAAGTACTCGTAGCCTCCAACAATGCCAAGAAGCTCGGTGAGCTACGCACCATCTTGGAAAACGCAGGTCTGAGCAG
CGTCGAGGTAGTGCCGCTTTCGGCAATCGACGCCTACGACGAGCCCGTAGAAGACGGCCGCACCTTCGCCGACAACGCCC
TAATTAAGGCCCGTGCGGGTGCACACCACAGTGGGCTTATCACGATTGCCGATGACTCTGGGTTCGCCGTTGAAGAACTC
AACGGAATGCCAGGGGTGCTGTCTGCTCGCTGGTCTGGGCAACATGGCAATGACGCAACCAACAACGAGTTGGTGCTTGC
TCAGATGAAACATGTCCCAGAGGAGCGTCGACACGCGGCGTTTGTGTCCGTCTGTGCGCTCGTGACCCCCGACGGCGACG
AACACATCGTCGAGGGGCGCTGGGAAGGTCGCATGCTCACCGCACCCCGCGGCGCCAACGGCTTCGGTTACGACCCCCTG
TTCGTACCCGCCGAAGAAGACGCAGCCGGCACTGGGCGCACCTCGGCAGAAATGAGCCCAGCGGAAAAGAACGCCATCTC
ACACCGCGGCAAAGCGCTTCAACAACTCGTCCCCATCATCGCGGGATACAGCACATTTTTTTAA

Upstream 100 bases:

>100_bases
AGCACAACACCTTTGATCGTGATGAGCTTGCCGTCATCTTGGACTTCGCGCAGAAGGGCTGCCAAGAACTGTTCGCCGCA
CAGAAGGCAGCTCTAGAACA

Downstream 100 bases:

>100_bases
TCACGATCCAGCTGGAACGTCTCAGTGACATCCTTACGACGCCAGTGCTCAACAAAGAAGGACAAGAACGGCACCACGCC
ACCCAGCGCTGTGACTAGCC

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MKVLVASNNAKKLGELRTILENAGLSSVEVVPLSAIDAYDEPVEDGRTFADNALIKARAGAHHSGLITIADDSGFAVEEL
NGMPGVLSARWSGQHGNDATNNELVLAQMKHVPEERRHAAFVSVCALVTPDGDEHIVEGRWEGRMLTAPRGANGFGYDPL
FVPAEEDAAGTGRTSAEMSPAEKNAISHRGKALQQLVPIIAGYSTFF

Sequences:

>Translated_207_residues
MKVLVASNNAKKLGELRTILENAGLSSVEVVPLSAIDAYDEPVEDGRTFADNALIKARAGAHHSGLITIADDSGFAVEEL
NGMPGVLSARWSGQHGNDATNNELVLAQMKHVPEERRHAAFVSVCALVTPDGDEHIVEGRWEGRMLTAPRGANGFGYDPL
FVPAEEDAAGTGRTSAEMSPAEKNAISHRGKALQQLVPIIAGYSTFF
>Mature_207_residues
MKVLVASNNAKKLGELRTILENAGLSSVEVVPLSAIDAYDEPVEDGRTFADNALIKARAGAHHSGLITIADDSGFAVEEL
NGMPGVLSARWSGQHGNDATNNELVLAQMKHVPEERRHAAFVSVCALVTPDGDEHIVEGRWEGRMLTAPRGANGFGYDPL
FVPAEEDAAGTGRTSAEMSPAEKNAISHRGKALQQLVPIIAGYSTFF

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=201, Percent_Identity=42.2885572139304, Blast_Score=139, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6322529, Length=199, Percent_Identity=29.1457286432161, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_CORDI (Q6NFN7)

Other databases:

- EMBL:   BX248359
- RefSeq:   NP_940187.1
- ProteinModelPortal:   Q6NFN7
- SMR:   Q6NFN7
- GeneID:   2649225
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1850
- NMPDR:   fig|257309.1.peg.1778
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- PhylomeDB:   Q6NFN7
- ProtClustDB:   PRK00120
- BioCyc:   CDIP257309:DIP1850-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 22032; Mature: 22032

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVASNNAKKLGELRTILENAGLSSVEVVPLSAIDAYDEPVEDGRTFADNALIKARAG
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCHHCCCEECCCCEEEECCC
AHHSGLITIADDSGFAVEELNGMPGVLSARWSGQHGNDATNNELVLAQMKHVPEERRHAA
CCCCCEEEEECCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCCEEEHHHHCCCHHHHHHH
FVSVCALVTPDGDEHIVEGRWEGRMLTAPRGANGFGYDPLFVPAEEDAAGTGRTSAEMSP
HHHHHEEECCCCCCCEECCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
AEKNAISHRGKALQQLVPIIAGYSTFF
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVLVASNNAKKLGELRTILENAGLSSVEVVPLSAIDAYDEPVEDGRTFADNALIKARAG
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCHHCCCEECCCCEEEECCC
AHHSGLITIADDSGFAVEELNGMPGVLSARWSGQHGNDATNNELVLAQMKHVPEERRHAA
CCCCCEEEEECCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCCEEEHHHHCCCHHHHHHH
FVSVCALVTPDGDEHIVEGRWEGRMLTAPRGANGFGYDPLFVPAEEDAAGTGRTSAEMSP
HHHHHEEECCCCCCCEECCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
AEKNAISHRGKALQQLVPIIAGYSTFF
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910