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The map label for this gene is orn

Identifier: 38234384

GI number: 38234384

Start: 1863228

End: 1863860

Strand: Direct

Name: orn

Synonym: DIP1813

Alternate gene names: 38234384

Gene position: 1863228-1863860 (Clockwise)

Preceding gene: 38234383

Following gene: 38234385

Centisome position: 74.87

GC content: 53.08

Gene sequence:

>633_bases
ATGGTAGAAACTGTTCACCCAAAAAATGATCGTTTAGTGTGGATTGACCTTGAGATGACTGGCCTTGAGTTGGATCGCCA
TGTCATTGTGGAGGTTGCTGCGCTTATTACGGATGCGGATCTCAACATTATCGGCGAGGGCGTGGATCTGGTGGTTCATG
CTACGCCTGAGCAGTTGGCGGAGATGGATGACTTTGTGACCACGATGCATACGTCGTCTGGCCTGTTGGAGGAGATTAAG
GCGTCGACTGTTTCTTTGCAGGAGGCAGAGGATGCGGTGTTGGCGTTGATTGCGCAGCATTGCGATCCGGAGCATCCGGC
GCCGTTGGCGGGTAATTCGATTGCGACGGATCGTTCGTTTATTCGTGCTCAGATGCCGCGGCTGGACAAGGCGTTGCATT
ACCGCATGGTGGATGTGTCTTCGTTGAAGGAGCTGTCGCGCCGTTGGGCGCCGCGTGTGTATTTTAATCAGCCTGATAAG
GGGATGGCACATCGCGCGTTGGCGGATATTGTGGAGTCGATTCGCGAGTTGGATTATTACCGTCGAGCGTGGCTTATTAG
CGATCCAACTACTGAAGATGCGGAGGACGCTAAGGCCAATGCAACGGCCTCTTACCAGCAGTTTTTGCAATAA

Upstream 100 bases:

>100_bases
GATAATGAATGCGGTGTCGTTGGTGGCGCCTACGGCGGTGTTGGCTCCTGTGATGGGGTGGTTCTACGCCAAGATGGCGT
AGAGGGGTAGCGTTATCGAC

Downstream 100 bases:

>100_bases
TCGGTTTGTGGGTTAATATTGTCACCGTTGCTTAAGCAAGCAGCAAATGGTGGCTGTAGTTCAGCTGGTAGAGCACCAGG
TTGTGATCCTGGGTGTCGCG

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MVETVHPKNDRLVWIDLEMTGLELDRHVIVEVAALITDADLNIIGEGVDLVVHATPEQLAEMDDFVTTMHTSSGLLEEIK
ASTVSLQEAEDAVLALIAQHCDPEHPAPLAGNSIATDRSFIRAQMPRLDKALHYRMVDVSSLKELSRRWAPRVYFNQPDK
GMAHRALADIVESIRELDYYRRAWLISDPTTEDAEDAKANATASYQQFLQ

Sequences:

>Translated_210_residues
MVETVHPKNDRLVWIDLEMTGLELDRHVIVEVAALITDADLNIIGEGVDLVVHATPEQLAEMDDFVTTMHTSSGLLEEIK
ASTVSLQEAEDAVLALIAQHCDPEHPAPLAGNSIATDRSFIRAQMPRLDKALHYRMVDVSSLKELSRRWAPRVYFNQPDK
GMAHRALADIVESIRELDYYRRAWLISDPTTEDAEDAKANATASYQQFLQ
>Mature_210_residues
MVETVHPKNDRLVWIDLEMTGLELDRHVIVEVAALITDADLNIIGEGVDLVVHATPEQLAEMDDFVTTMHTSSGLLEEIK
ASTVSLQEAEDAVLALIAQHCDPEHPAPLAGNSIATDRSFIRAQMPRLDKALHYRMVDVSSLKELSRRWAPRVYFNQPDK
GMAHRALADIVESIRELDYYRRAWLISDPTTEDAEDAKANATASYQQFLQ

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=171, Percent_Identity=48.5380116959064, Blast_Score=173, Evalue=1e-43,
Organism=Escherichia coli, GI87082382, Length=172, Percent_Identity=50, Blast_Score=169, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17557752, Length=176, Percent_Identity=42.6136363636364, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6323088, Length=191, Percent_Identity=37.17277486911, Blast_Score=120, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21355135, Length=170, Percent_Identity=45.2941176470588, Blast_Score=160, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_CORDI (P61650)

Other databases:

- EMBL:   BX248359
- RefSeq:   NP_940151.1
- ProteinModelPortal:   P61650
- SMR:   P61650
- GeneID:   2649441
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1813
- NMPDR:   fig|257309.1.peg.1742
- HOGENOM:   HBG448545
- OMA:   ARRWYPR
- PhylomeDB:   P61650
- ProtClustDB:   PRK05359
- BioCyc:   CDIP257309:DIP1813-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 23562; Mature: 23562

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: ACT_SITE 134-134

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVETVHPKNDRLVWIDLEMTGLELDRHVIVEVAALITDADLNIIGEGVDLVVHATPEQLA
CCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEECCCEEEEEECCHHHHH
EMDDFVTTMHTSSGLLEEIKASTVSLQEAEDAVLALIAQHCDPEHPAPLAGNSIATDRSF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
IRAQMPRLDKALHYRMVDVSSLKELSRRWAPRVYFNQPDKGMAHRALADIVESIRELDYY
HHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHH
RRAWLISDPTTEDAEDAKANATASYQQFLQ
HHEEEECCCCCCCCHHHCCCCHHHHHHHCC
>Mature Secondary Structure
MVETVHPKNDRLVWIDLEMTGLELDRHVIVEVAALITDADLNIIGEGVDLVVHATPEQLA
CCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEECCCEEEEEECCHHHHH
EMDDFVTTMHTSSGLLEEIKASTVSLQEAEDAVLALIAQHCDPEHPAPLAGNSIATDRSF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
IRAQMPRLDKALHYRMVDVSSLKELSRRWAPRVYFNQPDKGMAHRALADIVESIRELDYY
HHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHH
RRAWLISDPTTEDAEDAKANATASYQQFLQ
HHEEEECCCCCCCCHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910