Click here to switch to the map view.

The map label for this gene is ycnB [H]

Identifier: 38234323

GI number: 38234323

Start: 1796249

End: 1797652

Strand: Direct

Name: ycnB [H]

Synonym: DIP1752

Alternate gene names: 38234323

Gene position: 1796249-1797652 (Clockwise)

Preceding gene: 38234322

Following gene: 38234324

Centisome position: 72.18

GC content: 56.55

Gene sequence:

>1404_bases
ATGAAGGTACGCACGGTCCCCCTCATGTTGGCGTTACTTGCCGCAGTGTTTGCTTTCCAATTAAATGCGTCCATGCTTTC
TCCGGCATTGGCCACCATGGAAAAAGAACTTAACGCCACCTCTGCCCAAATTGGGCTTACCCAGACTGCATTTTTTACCG
CGGCTGCACTATTTTCCTTGTTCTTGCCTCGCTGGGGTGATTTGATTGGGCGTCGCAAAGTTCTTGTGGCAATGATGGCT
TTTACTGCTATCGGCTGTGTGGTTGCTGCTCTTGCACCAAATGTCACGGTGCTATTTATTGGCCGCGTCATCCAGGGTGT
TGCTGGGCCGACGGTGCCCTTGTGTCTCATTATGTTGCGTCAGCACGTACCCGATGAAAAGCAGTATGCACTGTTGCTGG
GTATTCTCACCTCAGTCAATGGCGGCATTGGCGGCGTCGATGCGCTGCTAGGCGGCTGGCTGGCAGGCTCGTTTGGTTTC
CGATCAATCTTCTGGGTCATGGCGGCGGTGTGTGTCGTCGCGGTGATCGTCGCACAACTGTTTACTACCGAATCCACGGC
TGAGGAAACCGCCCCCATGGACTGGGCGGGTGTGGCTCCGTTGGCCGTTGCGATCGGTGCGTTGTTGATCGCATTCAACG
AAGCCGGCAAGCTTGGCGACGCCCACTGGTTGCTCGTAGCTGTACTCGCCATCATTGGTGTGGCCGGTGTGATGATCTTC
TGGAAAGTCGAGCAAAAAGTAGCCCACCCTCTGGTCACTATCAACTACCTGGCGCAGCGTCGCACGTGGGCGCTGCTACT
GACCACACTGCTGACCATGACTGGCGTGTTCGCGGTTATGAACGGCCTGATTCCGAACTTGGCCCAAGCAGCTGAAGGCC
CAGGCCTTGCAGCGGATGTTGTTTCTTGGTGGACGCTAACCCCGTACGCCTTGGCCGGCCTTTCCTTTGGTCCTATCGCC
GGCACCCTCGCAGCGCGCTGGGGATACACCTTGGTGCTTCGGATCGGCTTGGTGGGTACACTCCTCGGCCTTATTGCCAC
GGCCACCCTCAGTAGTACGTTGACCCCGGCGCTGTTACTCATAATCAGCCTGTTTGTTGGCGTTACCTACGCGGGCATCG
CCAACATCATGCTCAACGGACTTGGCATCGTGCTCTCCCCCGCAGATAACCAAGGCTATCTGCCAGGAATGAACGCCGGT
GCATTTAACCTCGGCGCTGGTTTATCCTTCGCCGTATTGTTTGCCGTGACCACGGCCACCGGCTACCAGATTGGCATTGT
CACAGGTGCCGTTATTGTCGCCTGCGCGCTGGGCACTTCTTTGTTGATCCCCAAACCGGAAACAATCTCCGATACGCTCG
CAGCTGTCACCGCTACCGAAACTGCACAAGGACGCTCACTATGA

Upstream 100 bases:

>100_bases
TTGTGTCTTTATAGCCACATTTCACGTCTCTAGGTTTTTTGAAGTAACGCATTTAAAATCATCACGTCTTTATTTCTCAA
CGAGAAGGAATCCCCTCCTA

Downstream 100 bases:

>100_bases
CCCGAAAAATTATTCTCGACTGCGACCCAGGACACGACGACGCCGTAGCCATGCTACTCGCCGCAGCAAACCCCAACATC
GAACTGCTGGGAATCACCAC

Product: antibiotic ABC transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKVRTVPLMLALLAAVFAFQLNASMLSPALATMEKELNATSAQIGLTQTAFFTAAALFSLFLPRWGDLIGRRKVLVAMMA
FTAIGCVVAALAPNVTVLFIGRVIQGVAGPTVPLCLIMLRQHVPDEKQYALLLGILTSVNGGIGGVDALLGGWLAGSFGF
RSIFWVMAAVCVVAVIVAQLFTTESTAEETAPMDWAGVAPLAVAIGALLIAFNEAGKLGDAHWLLVAVLAIIGVAGVMIF
WKVEQKVAHPLVTINYLAQRRTWALLLTTLLTMTGVFAVMNGLIPNLAQAAEGPGLAADVVSWWTLTPYALAGLSFGPIA
GTLAARWGYTLVLRIGLVGTLLGLIATATLSSTLTPALLLIISLFVGVTYAGIANIMLNGLGIVLSPADNQGYLPGMNAG
AFNLGAGLSFAVLFAVTTATGYQIGIVTGAVIVACALGTSLLIPKPETISDTLAAVTATETAQGRSL

Sequences:

>Translated_467_residues
MKVRTVPLMLALLAAVFAFQLNASMLSPALATMEKELNATSAQIGLTQTAFFTAAALFSLFLPRWGDLIGRRKVLVAMMA
FTAIGCVVAALAPNVTVLFIGRVIQGVAGPTVPLCLIMLRQHVPDEKQYALLLGILTSVNGGIGGVDALLGGWLAGSFGF
RSIFWVMAAVCVVAVIVAQLFTTESTAEETAPMDWAGVAPLAVAIGALLIAFNEAGKLGDAHWLLVAVLAIIGVAGVMIF
WKVEQKVAHPLVTINYLAQRRTWALLLTTLLTMTGVFAVMNGLIPNLAQAAEGPGLAADVVSWWTLTPYALAGLSFGPIA
GTLAARWGYTLVLRIGLVGTLLGLIATATLSSTLTPALLLIISLFVGVTYAGIANIMLNGLGIVLSPADNQGYLPGMNAG
AFNLGAGLSFAVLFAVTTATGYQIGIVTGAVIVACALGTSLLIPKPETISDTLAAVTATETAQGRSL
>Mature_467_residues
MKVRTVPLMLALLAAVFAFQLNASMLSPALATMEKELNATSAQIGLTQTAFFTAAALFSLFLPRWGDLIGRRKVLVAMMA
FTAIGCVVAALAPNVTVLFIGRVIQGVAGPTVPLCLIMLRQHVPDEKQYALLLGILTSVNGGIGGVDALLGGWLAGSFGF
RSIFWVMAAVCVVAVIVAQLFTTESTAEETAPMDWAGVAPLAVAIGALLIAFNEAGKLGDAHWLLVAVLAIIGVAGVMIF
WKVEQKVAHPLVTINYLAQRRTWALLLTTLLTMTGVFAVMNGLIPNLAQAAEGPGLAADVVSWWTLTPYALAGLSFGPIA
GTLAARWGYTLVLRIGLVGTLLGLIATATLSSTLTPALLLIISLFVGVTYAGIANIMLNGLGIVLSPADNQGYLPGMNAG
AFNLGAGLSFAVLFAVTTATGYQIGIVTGAVIVACALGTSLLIPKPETISDTLAAVTATETAQGRSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=344, Percent_Identity=24.1279069767442, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48347; Mature: 48347

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]