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The map label for this gene is glnA2 [H]

Identifier: 38234244

GI number: 38234244

Start: 1708011

End: 1709351

Strand: Reverse

Name: glnA2 [H]

Synonym: DIP1671

Alternate gene names: 38234244

Gene position: 1709351-1708011 (Counterclockwise)

Preceding gene: 38234246

Following gene: 38234243

Centisome position: 68.69

GC content: 53.69

Gene sequence:

>1341_bases
ATGAACTCCCAACAAGAATTCGTGCTACAAGAAATCGAAGAACGAGACGTCCGTTTCGTACGACTTTGGTTTACTGACAT
CCTCGGATTTCTCAAATCAGTAGCAGTCGCCCCCTCAGAGCTCGAATCAGCCTTCGAAGAAGGCATCGGGTTCGACGGCT
CCGCGATCGAAGGATTCTCCCGAATCTCAGAAGCCGATACCATCGCGCTACCTGACCCCTCCACCTTCAAAATGCTGCCG
AGCCTCAACTCCGACCCCACTATGCGCTCGGCCCGAATGTTCTGCGACATTCTCAACCCCGACGGCCAGGCCTCCAACTC
GGACCCACGCCAAGTACTTCACAAACAAGTACAACTCGCCGCCGACGAAGGATTCCACTGCGTCGTCTCCCCAGAAATCG
AATTCTTCCTCGTCCAAAATCTTCGCACGAACGGCCTACCACCAGTACCAACCGACAACGGCGGGTACTTCGACCAAGCA
AGCCAAAACGACGCCCCCATGTTCCGTCGTGAAGCCATGCTTGCACTCGACCGCATGGGCATCCCCGTCGAATTCTCCCA
CCACGAAACCGCGCCGGGACAACAAGAAATTGATCTCCGGCACGCCGATGTGCTGACCATGGCAGACTCGATCATCACCT
TTAAACATCTGATGAAACAAGTCGCTATCGACAACAACATCGGTGCCACCTTTATGCCAAAGCCGTTCAGGGATCACGCC
GGCTCCGCGATGCACACGCACATGTCCTTGTTCGAAGGTGACATCAACGCATTCCATGATCCAGACGATGAATACGGACT
GTCCGTGACCGCAAAACGATTCATCGCCGGCATTATTCACCACGCCAATGAGATCTCGGCTGTGACTAACCAGTGGACCA
ACTCCTACAAGCGCATCCTCTTTGGCAACGAAGCACCAACTGCAGCCACATGGGGCGCCTCGAACCGGTCAGCACTCATT
CGCGTTCCTACCTACCGGCTAGCAAAAGCAGAATCACGTCGTGTGGAAGTACGTTCACCAGATTCCGCATGCAACCCTTA
CCTAGCATTTTCTGTGTTACTTGGCGCGGGACTTAAAGGCATCCGCGAAGGTTATGAGATCCCAGATGCAGCCGAAGAAG
ACATCAGCTCGCTTACACGTCGCGAGCGCCTCGCCATGGGATACAAAGACTTACCAACCAGCCTGGACCAAGCGCTACGA
GAAATGGAACGCAGTGAATTGGTAGCCGATATCCTTGGCGAGCATGTCTTTGAATACTTCCTACGTAACAAATGGCGCGA
ATGGCACGACTACCAGCAGCAAATTACCCCATGGGAATTGCGCAATAACCTCGACAATTAA

Upstream 100 bases:

>100_bases
CATGAAAATAACCACGCAACCCCCACCCAAAAGAGCCTATATACTGCGAAAACAATAGGGCGACCGTGCGATGTCACGAG
CAGAAAGTATCGTAAGAGAT

Downstream 100 bases:

>100_bases
TACATCGCCACGCTCGTTTTCATCGGTGACAAAACTCGGAGTACCACCACATGCGAAAAACACTTCCATCTATTGGAGCC
CTGGGCTTTAGCAACACCAA

Product: glutamine synthetase II

Products: NA

Alternate protein names: Glutamate--ammonia ligase 2 [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MNSQQEFVLQEIEERDVRFVRLWFTDILGFLKSVAVAPSELESAFEEGIGFDGSAIEGFSRISEADTIALPDPSTFKMLP
SLNSDPTMRSARMFCDILNPDGQASNSDPRQVLHKQVQLAADEGFHCVVSPEIEFFLVQNLRTNGLPPVPTDNGGYFDQA
SQNDAPMFRREAMLALDRMGIPVEFSHHETAPGQQEIDLRHADVLTMADSIITFKHLMKQVAIDNNIGATFMPKPFRDHA
GSAMHTHMSLFEGDINAFHDPDDEYGLSVTAKRFIAGIIHHANEISAVTNQWTNSYKRILFGNEAPTAATWGASNRSALI
RVPTYRLAKAESRRVEVRSPDSACNPYLAFSVLLGAGLKGIREGYEIPDAAEEDISSLTRRERLAMGYKDLPTSLDQALR
EMERSELVADILGEHVFEYFLRNKWREWHDYQQQITPWELRNNLDN

Sequences:

>Translated_446_residues
MNSQQEFVLQEIEERDVRFVRLWFTDILGFLKSVAVAPSELESAFEEGIGFDGSAIEGFSRISEADTIALPDPSTFKMLP
SLNSDPTMRSARMFCDILNPDGQASNSDPRQVLHKQVQLAADEGFHCVVSPEIEFFLVQNLRTNGLPPVPTDNGGYFDQA
SQNDAPMFRREAMLALDRMGIPVEFSHHETAPGQQEIDLRHADVLTMADSIITFKHLMKQVAIDNNIGATFMPKPFRDHA
GSAMHTHMSLFEGDINAFHDPDDEYGLSVTAKRFIAGIIHHANEISAVTNQWTNSYKRILFGNEAPTAATWGASNRSALI
RVPTYRLAKAESRRVEVRSPDSACNPYLAFSVLLGAGLKGIREGYEIPDAAEEDISSLTRRERLAMGYKDLPTSLDQALR
EMERSELVADILGEHVFEYFLRNKWREWHDYQQQITPWELRNNLDN
>Mature_446_residues
MNSQQEFVLQEIEERDVRFVRLWFTDILGFLKSVAVAPSELESAFEEGIGFDGSAIEGFSRISEADTIALPDPSTFKMLP
SLNSDPTMRSARMFCDILNPDGQASNSDPRQVLHKQVQLAADEGFHCVVSPEIEFFLVQNLRTNGLPPVPTDNGGYFDQA
SQNDAPMFRREAMLALDRMGIPVEFSHHETAPGQQEIDLRHADVLTMADSIITFKHLMKQVAIDNNIGATFMPKPFRDHA
GSAMHTHMSLFEGDINAFHDPDDEYGLSVTAKRFIAGIIHHANEISAVTNQWTNSYKRILFGNEAPTAATWGASNRSALI
RVPTYRLAKAESRRVEVRSPDSACNPYLAFSVLLGAGLKGIREGYEIPDAAEEDISSLTRRERLAMGYKDLPTSLDQALR
EMERSELVADILGEHVFEYFLRNKWREWHDYQQQITPWELRNNLDN

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=453, Percent_Identity=22.9580573951435, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1790301, Length=433, Percent_Identity=36.7205542725173, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI87081870, Length=453, Percent_Identity=28.0353200883002, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50266; Mature: 50266

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQQEFVLQEIEERDVRFVRLWFTDILGFLKSVAVAPSELESAFEEGIGFDGSAIEGFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHH
RISEADTIALPDPSTFKMLPSLNSDPTMRSARMFCDILNPDGQASNSDPRQVLHKQVQLA
HHCCCCEEECCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ADEGFHCVVSPEIEFFLVQNLRTNGLPPVPTDNGGYFDQASQNDAPMFRREAMLALDRMG
HCCCCEEEECCCEEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
IPVEFSHHETAPGQQEIDLRHADVLTMADSIITFKHLMKQVAIDNNIGATFMPKPFRDHA
CCEEECCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHC
GSAMHTHMSLFEGDINAFHDPDDEYGLSVTAKRFIAGIIHHANEISAVTNQWTNSYKRIL
CCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
FGNEAPTAATWGASNRSALIRVPTYRLAKAESRRVEVRSPDSACNPYLAFSVLLGAGLKG
ECCCCCCCCCCCCCCCCEEEECCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCHHH
IREGYEIPDAAEEDISSLTRRERLAMGYKDLPTSLDQALREMERSELVADILGEHVFEYF
HHCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNKWREWHDYQQQITPWELRNNLDN
HHHHHHHHHHHHHCCCHHHHHCCCCC
>Mature Secondary Structure
MNSQQEFVLQEIEERDVRFVRLWFTDILGFLKSVAVAPSELESAFEEGIGFDGSAIEGFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHH
RISEADTIALPDPSTFKMLPSLNSDPTMRSARMFCDILNPDGQASNSDPRQVLHKQVQLA
HHCCCCEEECCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ADEGFHCVVSPEIEFFLVQNLRTNGLPPVPTDNGGYFDQASQNDAPMFRREAMLALDRMG
HCCCCEEEECCCEEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
IPVEFSHHETAPGQQEIDLRHADVLTMADSIITFKHLMKQVAIDNNIGATFMPKPFRDHA
CCEEECCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHC
GSAMHTHMSLFEGDINAFHDPDDEYGLSVTAKRFIAGIIHHANEISAVTNQWTNSYKRIL
CCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
FGNEAPTAATWGASNRSALIRVPTYRLAKAESRRVEVRSPDSACNPYLAFSVLLGAGLKG
ECCCCCCCCCCCCCCCCEEEECCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCHHH
IREGYEIPDAAEEDISSLTRRERLAMGYKDLPTSLDQALREMERSELVADILGEHVFEYF
HHCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNKWREWHDYQQQITPWELRNNLDN
HHHHHHHHHHHHHCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA