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The map label for this gene is cobH [H]

Identifier: 38233820

GI number: 38233820

Start: 1233840

End: 1234490

Strand: Direct

Name: cobH [H]

Synonym: DIP1232

Alternate gene names: 38233820

Gene position: 1233840-1234490 (Clockwise)

Preceding gene: 38233819

Following gene: 38233821

Centisome position: 49.58

GC content: 51.31

Gene sequence:

>651_bases
GTGAGCTTCGAGTACATCACAGACGGTAATGAGATCTATCGGCAATCCTTTGCCATGATTCGTGAAGAGTCGGATTTAAG
CCGGTTCGATGACGAACAGGCACAAATCGCGGTTCGAATGATTCACGCAGCAGGCGAAGTTGATTTGGCGGAAGATATAG
AATTGTCCACCGATGTTGTTAATACCGCCCGTGATGCATTGCGCCGAGGCGCACCAATCTTGACTGATGTCAATATGGTG
AAAAGTGGCGTGACTCGTAAACGTTTGCCTGCAGACAACGAAGTAATCTGTCTGCTTAATGAACCTCGTTCGGTGGAACT
AGCTCGGAAACTTGGTACAACTCGATCTGCTGCCGCTGTCGAATTGTGGGAGCCACATATTGCTGGTGCAGTTGTTGCTA
TCGGCAATGCGCCTACGGCACTCTTTCACCTGCTTAATTGGCTTGCTGAGGACCCGCAGCGACCACGCCCTGCTGCGATT
TTGGGTATTCCTGTGGGATTCGTTGGCGCCGCAGAATCGAAAGCAGCATTAGCCAATGTTGCCCACGACTTAGGCGTCGA
ATTTGTCACTGTTCACGGGCGTCGTGGCGGATCAGCTATCACCTGTGCCGCGATCAATGCTCTGGCTACGGAAAAGGAGA
TTCTTCCATGA

Upstream 100 bases:

>100_bases
TAGTACACTTTTCAGGGTGTGATCGCAGGTGCGGTCACCCTTTGTCACATCACACTGAATACGTTGCGGTCGGCGACGGA
GAATATGAGGTTTCAGAACG

Downstream 100 bases:

>100_bases
CAGCTGTGACCGCAGGAAAGCTTATCGGAGTCGGAGTAGGTCCTGGTGATCCTGAGCTTCTTACCGTTAAAGCAGTAAAA
GCAATCAAGTCGGCAGATGT

Product: precorrin-8X methylmutase

Products: NA

Alternate protein names: HBA synthase; Precorrin isomerase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSFEYITDGNEIYRQSFAMIREESDLSRFDDEQAQIAVRMIHAAGEVDLAEDIELSTDVVNTARDALRRGAPILTDVNMV
KSGVTRKRLPADNEVICLLNEPRSVELARKLGTTRSAAAVELWEPHIAGAVVAIGNAPTALFHLLNWLAEDPQRPRPAAI
LGIPVGFVGAAESKAALANVAHDLGVEFVTVHGRRGGSAITCAAINALATEKEILP

Sequences:

>Translated_216_residues
MSFEYITDGNEIYRQSFAMIREESDLSRFDDEQAQIAVRMIHAAGEVDLAEDIELSTDVVNTARDALRRGAPILTDVNMV
KSGVTRKRLPADNEVICLLNEPRSVELARKLGTTRSAAAVELWEPHIAGAVVAIGNAPTALFHLLNWLAEDPQRPRPAAI
LGIPVGFVGAAESKAALANVAHDLGVEFVTVHGRRGGSAITCAAINALATEKEILP
>Mature_215_residues
SFEYITDGNEIYRQSFAMIREESDLSRFDDEQAQIAVRMIHAAGEVDLAEDIELSTDVVNTARDALRRGAPILTDVNMVK
SGVTRKRLPADNEVICLLNEPRSVELARKLGTTRSAAAVELWEPHIAGAVVAIGNAPTALFHLLNWLAEDPQRPRPAAIL
GIPVGFVGAAESKAALANVAHDLGVEFVTVHGRRGGSAITCAAINALATEKEILP

Specific function: Catalyzes the conversion of precorrin-8X to hydrogenobyrinic acid; a methyl migration reaction during the transformation of precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: =5.4.1.2 [H]

Molecular weight: Translated: 23245; Mature: 23114

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFEYITDGNEIYRQSFAMIREESDLSRFDDEQAQIAVRMIHAAGEVDLAEDIELSTDVV
CCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHCCHHHHHHH
NTARDALRRGAPILTDVNMVKSGVTRKRLPADNEVICLLNEPRSVELARKLGTTRSAAAV
HHHHHHHHCCCCCEEHHHHHHHCCCHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCHHHH
ELWEPHIAGAVVAIGNAPTALFHLLNWLAEDPQRPRPAAILGIPVGFVGAAESKAALANV
HHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
AHDLGVEFVTVHGRRGGSAITCAAINALATEKEILP
HHHCCCEEEEEECCCCCCEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFEYITDGNEIYRQSFAMIREESDLSRFDDEQAQIAVRMIHAAGEVDLAEDIELSTDVV
CCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHCCHHHHHHH
NTARDALRRGAPILTDVNMVKSGVTRKRLPADNEVICLLNEPRSVELARKLGTTRSAAAV
HHHHHHHHCCCCCEEHHHHHHHCCCHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCHHHH
ELWEPHIAGAVVAIGNAPTALFHLLNWLAEDPQRPRPAAILGIPVGFVGAAESKAALANV
HHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHH
AHDLGVEFVTVHGRRGGSAITCAAINALATEKEILP
HHHCCCEEEEEECCCCCCEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732194 [H]