Click here to switch to the map view.

The map label for this gene is secA2

Identifier: 38233793

GI number: 38233793

Start: 1203482

End: 1205776

Strand: Direct

Name: secA2

Synonym: DIP1203

Alternate gene names: 38233793

Gene position: 1203482-1205776 (Clockwise)

Preceding gene: 38233790

Following gene: 38233794

Centisome position: 48.36

GC content: 49.06

Gene sequence:

>2295_bases
GTGGCTGGATTCCGTTGGTTTTGGGATGCGATGGGTGGGAAAAATACCCGCAATCAAACGAAGAGTAAAAACATCGTTGC
CCAAGCTGCTAAGCGTGGTGTGCAGTTTGCTTCTCTTTCAGACGCAGATGTGGTTGCACGCGCACATGAGTGTGCTCAGC
ACTCAGACGATGAAAGCCGCGCCGATCTTTTAGCGTTGTTATCAATTGGGGCCCAGCGCTCCTTGTCTATGAATCCTTTT
AATGTGCAGCTGCAGGCAGTGCTGCGCATTCTAGAAGGCGACGTAATCCATATGGCTACTGGTGAAGGTAAAACCCTAGT
TGGGGCAATGGCCTCAGTCGGATACGCGTTGCAGGGGAAGCGAGTTCACTCAATAACCGTAAATGATTATTTGGCGGAGC
GTGATGCTGAGTGGATGGGTGATCTTGTTCGATATTTCGGGCTCACAGTCAGCGCGGTGACAGAATCTCTTAATACTGAG
CAACGCCGTCGCGCGTATGCATCTTCGATTGTTTATGCGCCAGTGACTGAAATTGGCTTTGATGTATTGAGGGATCAGTT
GGTTACGCAGCGTAGCCACGCCGTCCAAAACGGAGCAGATGTTGCGATCGTGGACGAAGCGGACTCAGTGCTTATCGACG
AAGCTCTCGTGCCACTTGTCTTAGCCGGAAATGAACCTGGTACGGCCCCAGCTGGCCGGATTACCGAAATTGTGCGGCGC
CTAAAAGAAAACGAGCATTACAGTGTGGATGCAGACCGGCGGAATGTATCACTAAATGATAAAGGTGCTGCGTTGTTGGA
ACAGGTGCTTGGTATTCAAAGTCTTTACGATGATGCTCATATAGGGACAACGCTCGTACAAGTGAATTTAGCGCTACATG
CGCAGGCATTACTTATTAGAGATGTTCATTACATCATTCGAGATGGAAAGATTGCTCTTATTGACGCCTCCAAAGGTCGT
GTTGCTCAGCTACAGCGTTGGCCTGATGGAGTTCAAGCAGCTGTAGAGGCTAAAGAAGGATTAGTCGTTACTGAAGGCGG
TCGAATCCTCGATACTCTCACGCTCCAATCGCTGATGGGGCGATATCCAATTGTTTGCGGCATGACTGGAACGGCTGTCG
AAGCTACGGATCAATTGCGACAGTTTTATGACCTTCGAGTATCAGTGATTGAACCGCACAAACAGTCCCAACGGTTTGAT
GAAGCTGACCGCGTTTATGCCACCCAAGCTGAAAAATTTCGAGCGCTGGTGAAAGAGATTGAGTTGCTTCATACCACTGG
ACAACCAGTTTTGATTGGTACTAGCGATGTCTCAGAATCTGAAGAATTAGCGCAAGCCTTACAGGCACGAGACATCACGG
TCAATGTATTGAACGCTAAAAATGACGCGGAAGAAGCACAGATCATTGCGGAGGCGGGAGACATCGGCCGGGTGACGGTT
TCTACTCAGATGGCTGGCCGTGGAACCGATATTCGCCTCGGTGGGGCAAACGAAAAAGATAGGGACGCAGTAGTAGCAAA
GGGGGGACTTGCGGTTATCGGATCCAGTCGTCACCGCAGTTCCCGTTTGGATAATCAGCTGCGTGGTCGTGCCGGTCGGC
AAGGCGACCCAGGCCTTTCTCTGTTTTTCGTGTCTTTAGAAGACGACGTCGTTGTCGTAGGCGGTGCCGGAGAAGAAATT
AAAGCCTTGCCGGATGCTGATGGTCGCATTGATTCCAAGAGAATTACTGATTTTGTAGCGCACTGTCAACGTGTAACCGA
AGGGCAGTTACTGGAAATTCATTCTCAAACATGGAAATACAATAAATTGTTGGCGGATCAACGAGTCATTATCGATGAGC
GTCGTGCGCGACTTCTCGATACTGATCAGGCGTGGGTGGAGCTATCAGAGGCGGTGCCTGAAAAAGCTCATAAATTGAGC
GACAAATTAGATCCAGCGATTCTTGTTCAGGCTGCACGAGAGGTCATGCTCTATCATCTTGACCGCTGTTGGAGTGATCA
CCTAGCACTTATGGATCATGTCCGTGAGTCCATACATTTACGTACTATTGCACGAGAAACTCCGCTTGATGAATATCACC
GAATTGCAGTACGAGAGTTTAAACAGTTAGCGCAACGTGCGGTTGATCTTGCTGTAGAGACTTTTCGGGACGTAACTATT
GACCAAGACGGAGCGCATTTGGCGGACGCTGGCCTAACGCGGCCATCTGCAACGTGGACCTACATGGTTAGCGATAATCC
GCTTTCAAATAATAATCGTTCAGTAATAAATGGAATAGGAAGTATTTTTAGATAG

Upstream 100 bases:

>100_bases
CAGACAGTGACAGTCTCAGACATTAGATTGAATTACTGAAATAGAGTTAAATAGTTTTACAAGCAGATTCAATTGCAAAT
GCTAAAAGGAAGGCAAGAGA

Downstream 100 bases:

>100_bases
ACGTTGTGCTGCCGTGTATAAACTTGTTTAAAATGGCAGCTCAAAGGTAGATATTGGAAAATAATCCTCTCTCCTTGGTC
ATCACGGTCAAACTAGCGCT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 764; Mature: 763

Protein sequence:

>764_residues
MAGFRWFWDAMGGKNTRNQTKSKNIVAQAAKRGVQFASLSDADVVARAHECAQHSDDESRADLLALLSIGAQRSLSMNPF
NVQLQAVLRILEGDVIHMATGEGKTLVGAMASVGYALQGKRVHSITVNDYLAERDAEWMGDLVRYFGLTVSAVTESLNTE
QRRRAYASSIVYAPVTEIGFDVLRDQLVTQRSHAVQNGADVAIVDEADSVLIDEALVPLVLAGNEPGTAPAGRITEIVRR
LKENEHYSVDADRRNVSLNDKGAALLEQVLGIQSLYDDAHIGTTLVQVNLALHAQALLIRDVHYIIRDGKIALIDASKGR
VAQLQRWPDGVQAAVEAKEGLVVTEGGRILDTLTLQSLMGRYPIVCGMTGTAVEATDQLRQFYDLRVSVIEPHKQSQRFD
EADRVYATQAEKFRALVKEIELLHTTGQPVLIGTSDVSESEELAQALQARDITVNVLNAKNDAEEAQIIAEAGDIGRVTV
STQMAGRGTDIRLGGANEKDRDAVVAKGGLAVIGSSRHRSSRLDNQLRGRAGRQGDPGLSLFFVSLEDDVVVVGGAGEEI
KALPDADGRIDSKRITDFVAHCQRVTEGQLLEIHSQTWKYNKLLADQRVIIDERRARLLDTDQAWVELSEAVPEKAHKLS
DKLDPAILVQAAREVMLYHLDRCWSDHLALMDHVRESIHLRTIARETPLDEYHRIAVREFKQLAQRAVDLAVETFRDVTI
DQDGAHLADAGLTRPSATWTYMVSDNPLSNNNRSVINGIGSIFR

Sequences:

>Translated_764_residues
MAGFRWFWDAMGGKNTRNQTKSKNIVAQAAKRGVQFASLSDADVVARAHECAQHSDDESRADLLALLSIGAQRSLSMNPF
NVQLQAVLRILEGDVIHMATGEGKTLVGAMASVGYALQGKRVHSITVNDYLAERDAEWMGDLVRYFGLTVSAVTESLNTE
QRRRAYASSIVYAPVTEIGFDVLRDQLVTQRSHAVQNGADVAIVDEADSVLIDEALVPLVLAGNEPGTAPAGRITEIVRR
LKENEHYSVDADRRNVSLNDKGAALLEQVLGIQSLYDDAHIGTTLVQVNLALHAQALLIRDVHYIIRDGKIALIDASKGR
VAQLQRWPDGVQAAVEAKEGLVVTEGGRILDTLTLQSLMGRYPIVCGMTGTAVEATDQLRQFYDLRVSVIEPHKQSQRFD
EADRVYATQAEKFRALVKEIELLHTTGQPVLIGTSDVSESEELAQALQARDITVNVLNAKNDAEEAQIIAEAGDIGRVTV
STQMAGRGTDIRLGGANEKDRDAVVAKGGLAVIGSSRHRSSRLDNQLRGRAGRQGDPGLSLFFVSLEDDVVVVGGAGEEI
KALPDADGRIDSKRITDFVAHCQRVTEGQLLEIHSQTWKYNKLLADQRVIIDERRARLLDTDQAWVELSEAVPEKAHKLS
DKLDPAILVQAAREVMLYHLDRCWSDHLALMDHVRESIHLRTIARETPLDEYHRIAVREFKQLAQRAVDLAVETFRDVTI
DQDGAHLADAGLTRPSATWTYMVSDNPLSNNNRSVINGIGSIFR
>Mature_763_residues
AGFRWFWDAMGGKNTRNQTKSKNIVAQAAKRGVQFASLSDADVVARAHECAQHSDDESRADLLALLSIGAQRSLSMNPFN
VQLQAVLRILEGDVIHMATGEGKTLVGAMASVGYALQGKRVHSITVNDYLAERDAEWMGDLVRYFGLTVSAVTESLNTEQ
RRRAYASSIVYAPVTEIGFDVLRDQLVTQRSHAVQNGADVAIVDEADSVLIDEALVPLVLAGNEPGTAPAGRITEIVRRL
KENEHYSVDADRRNVSLNDKGAALLEQVLGIQSLYDDAHIGTTLVQVNLALHAQALLIRDVHYIIRDGKIALIDASKGRV
AQLQRWPDGVQAAVEAKEGLVVTEGGRILDTLTLQSLMGRYPIVCGMTGTAVEATDQLRQFYDLRVSVIEPHKQSQRFDE
ADRVYATQAEKFRALVKEIELLHTTGQPVLIGTSDVSESEELAQALQARDITVNVLNAKNDAEEAQIIAEAGDIGRVTVS
TQMAGRGTDIRLGGANEKDRDAVVAKGGLAVIGSSRHRSSRLDNQLRGRAGRQGDPGLSLFFVSLEDDVVVVGGAGEEIK
ALPDADGRIDSKRITDFVAHCQRVTEGQLLEIHSQTWKYNKLLADQRVIIDERRARLLDTDQAWVELSEAVPEKAHKLSD
KLDPAILVQAAREVMLYHLDRCWSDHLALMDHVRESIHLRTIARETPLDEYHRIAVREFKQLAQRAVDLAVETFRDVTID
QDGAHLADAGLTRPSATWTYMVSDNPLSNNNRSVINGIGSIFR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=805, Percent_Identity=33.5403726708075, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA2_CORDI (Q6NHD5)

Other databases:

- EMBL:   BX248357
- RefSeq:   NP_939560.1
- HSSP:   P28366
- ProteinModelPortal:   Q6NHD5
- SMR:   Q6NHD5
- GeneID:   2649759
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1203
- NMPDR:   fig|257309.1.peg.1151
- HOGENOM:   HBG284200
- OMA:   QRVTEGQ
- ProtClustDB:   PRK12326
- BioCyc:   CDIP257309:DIP1203-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 83955; Mature: 83824

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGFRWFWDAMGGKNTRNQTKSKNIVAQAAKRGVQFASLSDADVVARAHECAQHSDDESR
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCCCHHH
ADLLALLSIGAQRSLSMNPFNVQLQAVLRILEGDVIHMATGEGKTLVGAMASVGYALQGK
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCHHCCCC
RVHSITVNDYLAERDAEWMGDLVRYFGLTVSAVTESLNTEQRRRAYASSIVYAPVTEIGF
EEEEEEHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHEEECCHHHHHH
DVLRDQLVTQRSHAVQNGADVAIVDEADSVLIDEALVPLVLAGNEPGTAPAGRITEIVRR
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHH
LKENEHYSVDADRRNVSLNDKGAALLEQVLGIQSLYDDAHIGTTLVQVNLALHAQALLIR
HHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHCCEEEEEEEHHHHHHHHHHH
DVHYIIRDGKIALIDASKGRVAQLQRWPDGVQAAVEAKEGLVVTEGGRILDTLTLQSLMG
HHHHHHCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHC
RYPIVCGMTGTAVEATDQLRQFYDLRVSVIEPHKQSQRFDEADRVYATQAEKFRALVKEI
CCCEEECCCCCHHHHHHHHHHHHHCCCEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
ELLHTTGQPVLIGTSDVSESEELAQALQARDITVNVLNAKNDAEEAQIIAEAGDIGRVTV
HHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCEEEE
STQMAGRGTDIRLGGANEKDRDAVVAKGGLAVIGSSRHRSSRLDNQLRGRAGRQGDPGLS
EEEECCCCCEEEECCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCE
LFFVSLEDDVVVVGGAGEEIKALPDADGRIDSKRITDFVAHCQRVTEGQLLEIHSQTWKY
EEEEEECCCEEEECCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
NKLLADQRVIIDERRARLLDTDQAWVELSEAVPEKAHKLSDKLDPAILVQAAREVMLYHL
HHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DRCWSDHLALMDHVRESIHLRTIARETPLDEYHRIAVREFKQLAQRAVDLAVETFRDVTI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DQDGAHLADAGLTRPSATWTYMVSDNPLSNNNRSVINGIGSIFR
CCCCCCHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AGFRWFWDAMGGKNTRNQTKSKNIVAQAAKRGVQFASLSDADVVARAHECAQHSDDESR
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCCCHHH
ADLLALLSIGAQRSLSMNPFNVQLQAVLRILEGDVIHMATGEGKTLVGAMASVGYALQGK
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCHHCCCC
RVHSITVNDYLAERDAEWMGDLVRYFGLTVSAVTESLNTEQRRRAYASSIVYAPVTEIGF
EEEEEEHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHEEECCHHHHHH
DVLRDQLVTQRSHAVQNGADVAIVDEADSVLIDEALVPLVLAGNEPGTAPAGRITEIVRR
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHH
LKENEHYSVDADRRNVSLNDKGAALLEQVLGIQSLYDDAHIGTTLVQVNLALHAQALLIR
HHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHCCEEEEEEEHHHHHHHHHHH
DVHYIIRDGKIALIDASKGRVAQLQRWPDGVQAAVEAKEGLVVTEGGRILDTLTLQSLMG
HHHHHHCCCEEEEEECCCCCHHHHHHCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHC
RYPIVCGMTGTAVEATDQLRQFYDLRVSVIEPHKQSQRFDEADRVYATQAEKFRALVKEI
CCCEEECCCCCHHHHHHHHHHHHHCCCEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
ELLHTTGQPVLIGTSDVSESEELAQALQARDITVNVLNAKNDAEEAQIIAEAGDIGRVTV
HHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCEEEE
STQMAGRGTDIRLGGANEKDRDAVVAKGGLAVIGSSRHRSSRLDNQLRGRAGRQGDPGLS
EEEECCCCCEEEECCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCE
LFFVSLEDDVVVVGGAGEEIKALPDADGRIDSKRITDFVAHCQRVTEGQLLEIHSQTWKY
EEEEEECCCEEEECCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHH
NKLLADQRVIIDERRARLLDTDQAWVELSEAVPEKAHKLSDKLDPAILVQAAREVMLYHL
HHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DRCWSDHLALMDHVRESIHLRTIARETPLDEYHRIAVREFKQLAQRAVDLAVETFRDVTI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DQDGAHLADAGLTRPSATWTYMVSDNPLSNNNRSVINGIGSIFR
CCCCCCHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14602910