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The map label for this gene is yciL [C]

Identifier: 38233785

GI number: 38233785

Start: 1194036

End: 1195001

Strand: Direct

Name: yciL [C]

Synonym: DIP1195

Alternate gene names: 38233785

Gene position: 1194036-1195001 (Clockwise)

Preceding gene: 38233784

Following gene: 38233786

Centisome position: 47.98

GC content: 51.24

Gene sequence:

>966_bases
GTGAATAGAACCGCTCGCCGTGACGGCACACCGGAAAAGCCTCGTCGAGGCTCTCAGGGAGGCTCCCGTGGGGACTACGG
AAAGCCGAAACGTAGCCATGCCAAGCCACAATCGGCAAATTCGGGCCGTCCCATAAAGCAACGTAAACAGCGTGATTCAG
AAATGTTGATTTCTAATGCGCGTCCAGCACGGCACCAGCATGTAGGTCGTCGTGAAGCAGGAGATGGCAGTACTGAAGGC
ATTCGTCTGCAAAAAGTCCTTGCTCAGGCAGGTGTCGCCTCTCGTCGACACGCTGAGATTTTGATCGATGCCGGCCGTGT
TGAGGTCAACGGAAAAATCGTGATGACTCAGGGCATGAGAGTTAACCCAAATGTCGATGTCATTCGCGTTGATGGTGTAC
GAGTCAATGTTAATGAAAACTTGCAGTACTTCGTTCTCAATAAGCCTCGCGGGTTGCAATCGACTATGAGCGATGACATG
GGGCGGCCGTGTGTTGGCGACATCGTGGGAGAGAGAATTTCTGCAGGCCAGCGTTTGTTCCACGTGGGACGTCTCGACGC
GGCTACGGAAGGCTTGCTGCTACTCACTAACGATGGAGAACTCGCTAATCGGTTGATGCATCCTCGATATGAAGTTTCGA
AGACTTACTTGGCTACTGTTCTCGGTGAGGCGGATAAACGCCTTGTTAAGCAATTACGTGATGGTATCGAGCTTGATGAC
GGTCCAGCTAAGGCGGATCTTGTTCAGATCATTGATACTTTCCAAGGCAAGTCCTTGATTCGTATTGAGCTGCATGAAGG
TCGTAAGCACATCGTACGACGGATGCTCAAAACTGCAGGATTCCCAGTTCAACGACTAGTGCGAACCAAAATTCACACAA
TTCAGCTTGGTGAGCAAACCCCAGGAGCGATCCGAGCTCTCAACAGTAGCGAATTAGCTAGCTTGTACAAGGCGGTAGGG
ATGTAA

Upstream 100 bases:

>100_bases
TCAAATATGCAATAGATAGTGGATAAGCTAGAATTCTTGATTCTACTGCGTTACAGTGGCAGAGATTTATAACCGCATAA
TTTGATCGATAGGAAGTATC

Downstream 100 bases:

>100_bases
AATGAGCACAGCTGATAGCACTGCACTGAGCAATATGCCTGAGGGTGGGCTGATCGTAGCTGTCGATGGTCCTTCTGGAG
CAGGCAAGTCTACGGTTTGT

Product: putative pseudouridine synthase B

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MNRTARRDGTPEKPRRGSQGGSRGDYGKPKRSHAKPQSANSGRPIKQRKQRDSEMLISNARPARHQHVGRREAGDGSTEG
IRLQKVLAQAGVASRRHAEILIDAGRVEVNGKIVMTQGMRVNPNVDVIRVDGVRVNVNENLQYFVLNKPRGLQSTMSDDM
GRPCVGDIVGERISAGQRLFHVGRLDAATEGLLLLTNDGELANRLMHPRYEVSKTYLATVLGEADKRLVKQLRDGIELDD
GPAKADLVQIIDTFQGKSLIRIELHEGRKHIVRRMLKTAGFPVQRLVRTKIHTIQLGEQTPGAIRALNSSELASLYKAVG
M

Sequences:

>Translated_321_residues
MNRTARRDGTPEKPRRGSQGGSRGDYGKPKRSHAKPQSANSGRPIKQRKQRDSEMLISNARPARHQHVGRREAGDGSTEG
IRLQKVLAQAGVASRRHAEILIDAGRVEVNGKIVMTQGMRVNPNVDVIRVDGVRVNVNENLQYFVLNKPRGLQSTMSDDM
GRPCVGDIVGERISAGQRLFHVGRLDAATEGLLLLTNDGELANRLMHPRYEVSKTYLATVLGEADKRLVKQLRDGIELDD
GPAKADLVQIIDTFQGKSLIRIELHEGRKHIVRRMLKTAGFPVQRLVRTKIHTIQLGEQTPGAIRALNSSELASLYKAVG
M
>Mature_321_residues
MNRTARRDGTPEKPRRGSQGGSRGDYGKPKRSHAKPQSANSGRPIKQRKQRDSEMLISNARPARHQHVGRREAGDGSTEG
IRLQKVLAQAGVASRRHAEILIDAGRVEVNGKIVMTQGMRVNPNVDVIRVDGVRVNVNENLQYFVLNKPRGLQSTMSDDM
GRPCVGDIVGERISAGQRLFHVGRLDAATEGLLLLTNDGELANRLMHPRYEVSKTYLATVLGEADKRLVKQLRDGIELDD
GPAKADLVQIIDTFQGKSLIRIELHEGRKHIVRRMLKTAGFPVQRLVRTKIHTIQLGEQTPGAIRALNSSELASLYKAVG
M

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=228, Percent_Identity=40.7894736842105, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1788510, Length=238, Percent_Identity=33.6134453781513, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790453, Length=241, Percent_Identity=31.5352697095436, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081838, Length=185, Percent_Identity=31.3513513513514, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 35499; Mature: 35499

Theoretical pI: Translated: 11.10; Mature: 11.10

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTARRDGTPEKPRRGSQGGSRGDYGKPKRSHAKPQSANSGRPIKQRKQRDSEMLISNA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
RPARHQHVGRREAGDGSTEGIRLQKVLAQAGVASRRHAEILIDAGRVEVNGKIVMTQGMR
CCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCEEEECCEEEEECCEE
VNPNVDVIRVDGVRVNVNENLQYFVLNKPRGLQSTMSDDMGRPCVGDIVGERISAGQRLF
ECCCCCEEEECCEEEEECCCEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
HVGRLDAATEGLLLLTNDGELANRLMHPRYEVSKTYLATVLGEADKRLVKQLRDGIELDD
HHHCCCCCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GPAKADLVQIIDTFQGKSLIRIELHEGRKHIVRRMLKTAGFPVQRLVRTKIHTIQLGEQT
CCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHEEEECCCC
PGAIRALNSSELASLYKAVGM
CHHHEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MNRTARRDGTPEKPRRGSQGGSRGDYGKPKRSHAKPQSANSGRPIKQRKQRDSEMLISNA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
RPARHQHVGRREAGDGSTEGIRLQKVLAQAGVASRRHAEILIDAGRVEVNGKIVMTQGMR
CCHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCEEEECCEEEEECCEE
VNPNVDVIRVDGVRVNVNENLQYFVLNKPRGLQSTMSDDMGRPCVGDIVGERISAGQRLF
ECCCCCEEEECCEEEEECCCEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
HVGRLDAATEGLLLLTNDGELANRLMHPRYEVSKTYLATVLGEADKRLVKQLRDGIELDD
HHHCCCCCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GPAKADLVQIIDTFQGKSLIRIELHEGRKHIVRRMLKTAGFPVQRLVRTKIHTIQLGEQT
CCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHEEEECCCC
PGAIRALNSSELASLYKAVGM
CHHHEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]