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The map label for this gene is argD [H]

Identifier: 38233760

GI number: 38233760

Start: 1162520

End: 1163761

Strand: Direct

Name: argD [H]

Synonym: DIP1170

Alternate gene names: 38233760

Gene position: 1162520-1163761 (Clockwise)

Preceding gene: 38233759

Following gene: 38233761

Centisome position: 46.71

GC content: 47.5

Gene sequence:

>1242_bases
ATGTCTAAGAATGCGGCGAACACAGATTCACAATCGTCAGAGACTCAATGGGCTGATGTCATTATGAATACCTACGGCAC
GCCTCCTCTGACGATCACAGGAGGAAATGGCGCCACTCTTACGGATTCTGTAGGTAAAACGTACATCGATTTACTGGCAG
GAATTGCCGTAAACTCTTTGGGGCATGCGCATCCGGCCATTGTTGAGGCCGTAACAGAACAAATTTCAAATTTTGCTCAT
GTTTCAAATCTCTTCGGATCGCGACCAGTTATTGATACCGCAGCTCGGTTAATTCGACGCTTCGCGGAAGAAACCACCGA
CTCAACTCAAACTGCTCACGATACTCGAGTATTTTTCTGTAACTCAGGTACTGAAGCTAATGAGGCGGCATTCAAGTTGG
CTCGTATGACTGGAAAGAACCGAATATTAGCAGCGCAGCATGGTTTTCACGGTCGTACGATGGGAGCACTTGCTATGACG
GGCCAACCTGACAAACAAATGCCGTTTTATCCGCTGCCCGCAGGCGTTGAATTTTATCCCTATGGCGACATTGACTATTT
GCGCAAGCTTGTCCAAATCAACTCGACAGATGTCGCAGCCATAATTTTAGAGCCAATTCAAGGTGAAACTGGTGTTATTC
CTGCTCCAGATGGATTTTTGTCTGCGGTTAGGGGATTATGCAATGAATTTGACATTCTGATGATCGTTGATGAAGTCCAA
ACCGGAATCGGACGCACTGGAGATTTTTTCGCATTTCAGCATGAAACTGGTGTCATTCCCGACGTCGTAACTATGGCGAA
AGGTTTGGGAGGGGGATTACCGATTGGTGCGTGCCTTGCAACGGGAAAAGCGAAAGATTTGTTAGGTCCTGGCAAACATG
GCACGACTTTTGGTGGAAATCCGGTCTCTTGTGCCGCGGCAGGGGCAGTTTTGCGCACAATTGACGACGATTTCCTCGAG
AACGTCCAGCGTAAGAGTCACAAGTTAGTTAAAAGAATGAGCCGACTGCCTTTGGTTGAGTCGATCCGCGGACGTGGTTT
GATGCTTGGTGTGCTGTTGTCCGAGCCAGTCGCTAAAGAGTGCGTCAAACTGGCTTTAGAACATGGGCTCATCGTGAACG
CTCCTTCTGCGTCTGTGCTGCGACTTACTCCGCCTTTAGTTATCAGTGACGCAGAAATTCATGAATCAATTGAACGCCTT
TCAATAGTGCTGACTAAGATAAAGAAGAAAGAATGCCATTAG

Upstream 100 bases:

>100_bases
CATTCAGTGCTTCTTGAGTTACTGACTTCGGGCGGTGTTGGGACCATGGTTGTTCCCGATACAGAAATGACAAATGGGAC
AGTGTACCGAAAGGATAATC

Downstream 100 bases:

>100_bases
GGCGTTGTCTTCGGAAGAAAGAATAGATATGAGTACTCAAACCCGTGTACGCCACTTTTTAGCGGACGACGACCTTACGC
CTGCGCAGCAACGTGAAGTT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSKNAANTDSQSSETQWADVIMNTYGTPPLTITGGNGATLTDSVGKTYIDLLAGIAVNSLGHAHPAIVEAVTEQISNFAH
VSNLFGSRPVIDTAARLIRRFAEETTDSTQTAHDTRVFFCNSGTEANEAAFKLARMTGKNRILAAQHGFHGRTMGALAMT
GQPDKQMPFYPLPAGVEFYPYGDIDYLRKLVQINSTDVAAIILEPIQGETGVIPAPDGFLSAVRGLCNEFDILMIVDEVQ
TGIGRTGDFFAFQHETGVIPDVVTMAKGLGGGLPIGACLATGKAKDLLGPGKHGTTFGGNPVSCAAAGAVLRTIDDDFLE
NVQRKSHKLVKRMSRLPLVESIRGRGLMLGVLLSEPVAKECVKLALEHGLIVNAPSASVLRLTPPLVISDAEIHESIERL
SIVLTKIKKKECH

Sequences:

>Translated_413_residues
MSKNAANTDSQSSETQWADVIMNTYGTPPLTITGGNGATLTDSVGKTYIDLLAGIAVNSLGHAHPAIVEAVTEQISNFAH
VSNLFGSRPVIDTAARLIRRFAEETTDSTQTAHDTRVFFCNSGTEANEAAFKLARMTGKNRILAAQHGFHGRTMGALAMT
GQPDKQMPFYPLPAGVEFYPYGDIDYLRKLVQINSTDVAAIILEPIQGETGVIPAPDGFLSAVRGLCNEFDILMIVDEVQ
TGIGRTGDFFAFQHETGVIPDVVTMAKGLGGGLPIGACLATGKAKDLLGPGKHGTTFGGNPVSCAAAGAVLRTIDDDFLE
NVQRKSHKLVKRMSRLPLVESIRGRGLMLGVLLSEPVAKECVKLALEHGLIVNAPSASVLRLTPPLVISDAEIHESIERL
SIVLTKIKKKECH
>Mature_412_residues
SKNAANTDSQSSETQWADVIMNTYGTPPLTITGGNGATLTDSVGKTYIDLLAGIAVNSLGHAHPAIVEAVTEQISNFAHV
SNLFGSRPVIDTAARLIRRFAEETTDSTQTAHDTRVFFCNSGTEANEAAFKLARMTGKNRILAAQHGFHGRTMGALAMTG
QPDKQMPFYPLPAGVEFYPYGDIDYLRKLVQINSTDVAAIILEPIQGETGVIPAPDGFLSAVRGLCNEFDILMIVDEVQT
GIGRTGDFFAFQHETGVIPDVVTMAKGLGGGLPIGACLATGKAKDLLGPGKHGTTFGGNPVSCAAAGAVLRTIDDDFLEN
VQRKSHKLVKRMSRLPLVESIRGRGLMLGVLLSEPVAKECVKLALEHGLIVNAPSASVLRLTPPLVISDAEIHESIERLS
IVLTKIKKKECH

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=392, Percent_Identity=33.4183673469388, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI284507298, Length=294, Percent_Identity=37.0748299319728, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI13994255, Length=447, Percent_Identity=30.4250559284116, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI24119277, Length=423, Percent_Identity=27.4231678486998, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=27.2511848341232, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=27.906976744186, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=26.5402843601896, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI188536080, Length=432, Percent_Identity=24.537037037037, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI38679950, Length=432, Percent_Identity=24.537037037037, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI38679946, Length=432, Percent_Identity=24.537037037037, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=41.4572864321608, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1789759, Length=404, Percent_Identity=38.1188118811881, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI145693181, Length=394, Percent_Identity=36.8020304568528, Blast_Score=224, Evalue=6e-60,
Organism=Escherichia coli, GI1787560, Length=434, Percent_Identity=34.331797235023, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789016, Length=419, Percent_Identity=30.7875894988067, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786349, Length=363, Percent_Identity=31.129476584022, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786991, Length=429, Percent_Identity=27.2727272727273, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=403, Percent_Identity=30.272952853598, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI32564660, Length=440, Percent_Identity=29.0909090909091, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=275, Percent_Identity=32.3636363636364, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=436, Percent_Identity=29.5871559633028, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17541228, Length=430, Percent_Identity=25.1162790697674, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71981843, Length=177, Percent_Identity=26.5536723163842, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=394, Percent_Identity=39.8477157360406, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6323470, Length=425, Percent_Identity=32.9411764705882, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324386, Length=323, Percent_Identity=29.7213622291022, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=430, Percent_Identity=23.953488372093, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357415, Length=391, Percent_Identity=33.2480818414322, Blast_Score=218, Evalue=6e-57,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=28.5057471264368, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI161085790, Length=429, Percent_Identity=28.4382284382284, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21356575, Length=434, Percent_Identity=29.4930875576037, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281366494, Length=313, Percent_Identity=27.7955271565495, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24667139, Length=313, Percent_Identity=27.7955271565495, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24667143, Length=313, Percent_Identity=27.7955271565495, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 44054; Mature: 43923

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNAANTDSQSSETQWADVIMNTYGTPPLTITGGNGATLTDSVGKTYIDLLAGIAVNSL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCEECHHHHHHHHHHHHHHHHHHC
GHAHPAIVEAVTEQISNFAHVSNLFGSRPVIDTAARLIRRFAEETTDSTQTAHDTRVFFC
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
NSGTEANEAAFKLARMTGKNRILAAQHGFHGRTMGALAMTGQPDKQMPFYPLPAGVEFYP
CCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCCEECCCCCEEEC
YGDIDYLRKLVQINSTDVAAIILEPIQGETGVIPAPDGFLSAVRGLCNEFDILMIVDEVQ
CCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHH
TGIGRTGDFFAFQHETGVIPDVVTMAKGLGGGLPIGACLATGKAKDLLGPGKHGTTFGGN
HCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHCCCHHHCCCCCCCCCCCCCC
PVSCAAAGAVLRTIDDDFLENVQRKSHKLVKRMSRLPLVESIRGRGLMLGVLLSEPVAKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHCCHHHHH
CVKLALEHGLIVNAPSASVLRLTPPLVISDAEIHESIERLSIVLTKIKKKECH
HHHHHHHCCEEEECCCCCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKNAANTDSQSSETQWADVIMNTYGTPPLTITGGNGATLTDSVGKTYIDLLAGIAVNSL
CCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCEECHHHHHHHHHHHHHHHHHHC
GHAHPAIVEAVTEQISNFAHVSNLFGSRPVIDTAARLIRRFAEETTDSTQTAHDTRVFFC
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
NSGTEANEAAFKLARMTGKNRILAAQHGFHGRTMGALAMTGQPDKQMPFYPLPAGVEFYP
CCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEECCCCCCCCCCEECCCCCEEEC
YGDIDYLRKLVQINSTDVAAIILEPIQGETGVIPAPDGFLSAVRGLCNEFDILMIVDEVQ
CCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHH
TGIGRTGDFFAFQHETGVIPDVVTMAKGLGGGLPIGACLATGKAKDLLGPGKHGTTFGGN
HCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHCCCHHHCCCCCCCCCCCCCC
PVSCAAAGAVLRTIDDDFLENVQRKSHKLVKRMSRLPLVESIRGRGLMLGVLLSEPVAKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEHHHHCCHHHHH
CVKLALEHGLIVNAPSASVLRLTPPLVISDAEIHESIERLSIVLTKIKKKECH
HHHHHHHCCEEEECCCCCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8581175; 12948626 [H]