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The map label for this gene is infC [H]

Identifier: 38233750

GI number: 38233750

Start: 1152383

End: 1152886

Strand: Direct

Name: infC [H]

Synonym: DIP1160

Alternate gene names: 38233750

Gene position: 1152383-1152886 (Clockwise)

Preceding gene: 38233749

Following gene: 38233751

Centisome position: 46.31

GC content: 53.17

Gene sequence:

>504_bases
ATTAATGAGCGCATCCGAGTTCCCGAGGTTCGTCTAGTCGGACCGAACGGTGAACAGGTGGGCATCGTGCGTATCGACGA
CGCCCGTAAGCTTGCCTACGAAGCAGACCTTGACTTGGTTGAGGTTGCTCCGAATGCTAAACCGCCAGTCTGCAAAATTA
TGGACTATGGAAAGTTCAAATACGAGCAGGCGCAGAAGGCGCGTGAAGCTCGGAAGAACCAGCAGCAGACTGTGGTCAAG
GAGCAGAAGTTCCGTCCCAAGATCGATGACCACGATTACGAGACGAAGAAGAACAATGTGATCCGGTTCCTCGAAAAGGG
ATCCAAGGTAAAGGTCACTATCATGTTCCGCGGGCGTGAGCAGTCTCGTCCTGAACTTGGTTTCCGTCTCCTTGAGCGCC
TGGCTGGCGATGTTGCTGAGTATGGCATCGTTGAGTCCAAGCCAAAGCAGGATGGTCGTAATATGACCATGGTCTTTGGT
CCAGCGCGCAAGGGCAAGAAGTAG

Upstream 100 bases:

>100_bases
TTCTGTGTGTTCTTCCTTTGAAGAAGTTTCTATAAGCGATGGGCGCGGTATATCACATACATTTGCTACTTGAGGAGTCC
CCATCAGCGCTGAAGCTCGC

Downstream 100 bases:

>100_bases
ACACTTAAAACAAAAAGGACGTAATTTTCATGAAGCAGAAGACCCACAAGGGCACCGCTAAGCGCGTCAAGATCACCGGT
TCTGGCAAGCTCCGTCGTGA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MNERIRVPEVRLVGPNGEQVGIVRIDDARKLAYEADLDLVEVAPNAKPPVCKIMDYGKFKYEQAQKAREARKNQQQTVVK
EQKFRPKIDDHDYETKKNNVIRFLEKGSKVKVTIMFRGREQSRPELGFRLLERLAGDVAEYGIVESKPKQDGRNMTMVFG
PARKGKK

Sequences:

>Translated_167_residues
MNERIRVPEVRLVGPNGEQVGIVRIDDARKLAYEADLDLVEVAPNAKPPVCKIMDYGKFKYEQAQKAREARKNQQQTVVK
EQKFRPKIDDHDYETKKNNVIRFLEKGSKVKVTIMFRGREQSRPELGFRLLERLAGDVAEYGIVESKPKQDGRNMTMVFG
PARKGKK
>Mature_167_residues
MNERIRVPEVRLVGPNGEQVGIVRIDDARKLAYEADLDLVEVAPNAKPPVCKIMDYGKFKYEQAQKAREARKNQQQTVVK
EQKFRPKIDDHDYETKKNNVIRFLEKGSKVKVTIMFRGREQSRPELGFRLLERLAGDVAEYGIVESKPKQDGRNMTMVFG
PARKGKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=165, Percent_Identity=50.3030303030303, Blast_Score=153, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19232; Mature: 19232

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERIRVPEVRLVGPNGEQVGIVRIDDARKLAYEADLDLVEVAPNAKPPVCKIMDYGKFK
CCCCCCCCEEEEECCCCCEEEEEEECCCHHHHHHCCCCEEEECCCCCCCEEEEECCCCCH
YEQAQKAREARKNQQQTVVKEQKFRPKIDDHDYETKKNNVIRFLEKGSKVKVTIMFRGRE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCC
QSRPELGFRLLERLAGDVAEYGIVESKPKQDGRNMTMVFGPARKGKK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MNERIRVPEVRLVGPNGEQVGIVRIDDARKLAYEADLDLVEVAPNAKPPVCKIMDYGKFK
CCCCCCCCEEEEECCCCCEEEEEEECCCHHHHHHCCCCEEEECCCCCCCEEEEECCCCCH
YEQAQKAREARKNQQQTVVKEQKFRPKIDDHDYETKKNNVIRFLEKGSKVKVTIMFRGRE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCC
QSRPELGFRLLERLAGDVAEYGIVESKPKQDGRNMTMVFGPARKGKK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]