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The map label for this gene is atpB [H]

Identifier: 38233640

GI number: 38233640

Start: 1028202

End: 1028987

Strand: Direct

Name: atpB [H]

Synonym: DIP1046

Alternate gene names: 38233640

Gene position: 1028202-1028987 (Clockwise)

Preceding gene: 38233639

Following gene: 38233641

Centisome position: 41.32

GC content: 51.91

Gene sequence:

>786_bases
ATGAAGGGCGAGTTTCACGCGCCCTCCTTGGATCACGAATTTTTCCCGGATCCCATCTGGTTCGCCGATGTGGCGAACGG
TTGGTTCACAATCGACCGTCTGATGTTCGTCCGCCTGCTTATGGCGTTGGTCCTTGTAATCTTCTTCGCAGTCGCTATGC
GTAGCCCGAAGCTTGTTCCTTCCGGCTTGCAAAACGTTGCTGAATACCTTTTGGACTTCGTCCGAATTCACATTGCAGAA
GACATTCTGGGCAAGAAAGAGGGCAACCGCTTCTTGCCAATTCTGTCCACCATTTTCTTCGTGGTTTTGTTCTGCAACCT
GCCTTCGGTCATTCCATTCCTGAACATTTCGCCAAACGCGCGCATTGGTATGCCACTCGTTTTGGCGCTGTTCGGTTACA
TTGCCTTCATCTACGCAGGTGCTAAGCGCTACGGCTTCTTCAAGTATGTGAAGTCTTCGGTGGTTATTCCTAACCTTCCG
CCAGTTCTTCACTTGCTCGTTGTGCCACTCGAGTTCTTCTCGACATTCGTTCTGCGTCCGGCCACACTGACTCTTCGTCT
TATGGCCAACATGCTCGCAGGACACATCATTCTGGTGCTTCTTTTCTCTGCCACGAACTTCTTCTTCTGGCAGCTGAATG
GTTGGACTGCGCTGTCCGCCGTAACTTTGGTTGCGGGGATCGCGTTCACGCTGTTCGAGATGCTGGTGATTTTCTTGCAG
GCGTACATCTTCGCTCTGCTTTCTGCCGTGTACATCGAACTGGCGTTGCACGCCGACGAACACTGA

Upstream 100 bases:

>100_bases
GATTGCAGAGAGTTTTCAGACGTCCATCGCACCGCATGCTTGATTTCAGGTATATGCGGCCCGAAACTGGGAGAGAACGC
TGAGCGTTACAACTTTGGCC

Downstream 100 bases:

>100_bases
CCCCGCGGACCCGCGGATCACAATCTCTACATTATTCATATTGCCTAGTAAATAACTGGGCACCTAGAAAGGGAACGACA
CTTTCATGAACGAAGTCATC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKGEFHAPSLDHEFFPDPIWFADVANGWFTIDRLMFVRLLMALVLVIFFAVAMRSPKLVPSGLQNVAEYLLDFVRIHIAE
DILGKKEGNRFLPILSTIFFVVLFCNLPSVIPFLNISPNARIGMPLVLALFGYIAFIYAGAKRYGFFKYVKSSVVIPNLP
PVLHLLVVPLEFFSTFVLRPATLTLRLMANMLAGHIILVLLFSATNFFFWQLNGWTALSAVTLVAGIAFTLFEMLVIFLQ
AYIFALLSAVYIELALHADEH

Sequences:

>Translated_261_residues
MKGEFHAPSLDHEFFPDPIWFADVANGWFTIDRLMFVRLLMALVLVIFFAVAMRSPKLVPSGLQNVAEYLLDFVRIHIAE
DILGKKEGNRFLPILSTIFFVVLFCNLPSVIPFLNISPNARIGMPLVLALFGYIAFIYAGAKRYGFFKYVKSSVVIPNLP
PVLHLLVVPLEFFSTFVLRPATLTLRLMANMLAGHIILVLLFSATNFFFWQLNGWTALSAVTLVAGIAFTLFEMLVIFLQ
AYIFALLSAVYIELALHADEH
>Mature_261_residues
MKGEFHAPSLDHEFFPDPIWFADVANGWFTIDRLMFVRLLMALVLVIFFAVAMRSPKLVPSGLQNVAEYLLDFVRIHIAE
DILGKKEGNRFLPILSTIFFVVLFCNLPSVIPFLNISPNARIGMPLVLALFGYIAFIYAGAKRYGFFKYVKSSVVIPNLP
PVLHLLVVPLEFFSTFVLRPATLTLRLMANMLAGHIILVLLFSATNFFFWQLNGWTALSAVTLVAGIAFTLFEMLVIFLQ
AYIFALLSAVYIELALHADEH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=251, Percent_Identity=27.0916334661355, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 29422; Mature: 29422

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA