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The map label for this gene is sglT [H]

Identifier: 38233607

GI number: 38233607

Start: 985407

End: 987065

Strand: Direct

Name: sglT [H]

Synonym: DIP1012

Alternate gene names: 38233607

Gene position: 985407-987065 (Clockwise)

Preceding gene: 38233606

Following gene: 38233608

Centisome position: 39.6

GC content: 52.56

Gene sequence:

>1659_bases
ATGGATACCGCATTGAGGCTAGACGCGACGTGGGTCGATTACCTGCTTGTCGCCTTGTACTTTGTATTTGTTTTGGGCAT
CGGATGGGCCGCGAAAGCACGTGTGTCCTCCTCCATTGATTTCTTCCTATCTGGGCGCGGGCTGCCAGCTTGGGTCACAG
GTCTTGCCTTTGTCTCCGCCAACTTAGGCGCTGTGGAGATCATCGGCATGTCGGCTAACGGCGTGCAATATGGTTTCCAA
ACCATGCACTATTTCTGGATCGGCGCAGTACCTGCCATGGTGTTCCTAGGAATCGTGATGATGCCGTTCTACTACGGCTC
CAAGGTTCGCTCGGTTCCTGAATTTATGCGCCGCCGATTCGGTAGCGCAGCTCACTTGGTCAATGCTGTGTCCTTCGCTG
TGGCACAGCTGCTGATCGCCGGTGTAAACCTCTTCCTCCTAGCGAAGGTTGTCAACGCACTTCTCGGTTGGCCGCTGTGG
GTCGCCCTCGTATTGGCCGCGGTCATTGTGTTGTCGTACATCACTTTGGGCGGTTTGTCTGCCGCGATCTATAACGAGGT
GCTGCAGTTCTTTGTCATTCTTGCCATGCTGCTTCCTATCACCATCATTGGTCTTAATCGAGTAGGAGGGTGGCAGGGCC
TAAAGGAACAGGTTGCTATCGAGCACAACTTCCACACGTGGCCAGGCGTAGAGATTTCGGGTTTTGATAACCCAGTGATC
TCGGTGATTGGTATTACCTTTGGCTTGGGCTTTGTGCTGTCATTTGGTTATTGGACTACCAACTTCGTTGAGGTGCAACG
TGCTATGGCATCGGAGTCGATCTCTGCTGCTCGCAAGACTCCGATTATCGGTGCGTTTCCTAAGATGTTTGTTCCATTCC
TCGTGGTGCTTCCAGGTATGGTCGCATCGGTCACTGTTGCTGAGCTGATTGGTGATAATCCTGCCGGCAAGCCTAACGAC
GCCATCTTGTATCTCATGCGTGACCTTCTTCCCAACGGTCTGTTGGGCGTTGCTATTGCAGGTCTGTTGGCCTCGTTCAT
GGCTGGTATGGCCGCTAACATCTCGGCATTTAACACCGTGATCTCTTATGACATTTGGCAAACCTATGTGATCAAAGATC
GCGAAGATGACTACTACCTCAAGTTCGGACGCCTTGCCACTGTTGCCGCCACCTTGATCGCAGTGTTTACTGCGTTGCTT
GCCCAGAACTTTGGCAACATCATGGATTATCTGCAAACACTGTTTGGCTTTTTTAACGCACCACTGTTTGCCACCTTCAT
TTTGGGTATGTTCTGGAAGCGCATGACTCCTCACGCAGGTTGGACCGGCCTTGTGGCAGGTACTGCGTCGGCAATCTTCT
ACTGGTACTTGGCTACCTTTACTGAATCTTCTGCAACGCTGCTTAATCTGCCAGGACAAGGCACCGCATTCGTCGCTGCC
GGTATCGCGTTTAGCGTCGACATCCTCGTCTCCGTGATCGTTACCATGTTCACCCAGCCGAAGCCGGATCACGAGCTGGT
GGGCTTTGTAAAGTCTGTTACCCCAAAGGACCATTTCGAGGACCATTCCGAAGACGGCCAGCCGTGGTACCGCCGCACCG
TTCCACTAGGAATGCTGTGCTTAATCTTGGTCATCGCTCTCAACGTTATCTTTGCCTAG

Upstream 100 bases:

>100_bases
GATCGGCGCGGCATCTCCGTGGCACGGAACGATCACGATTTCCGCATATAACAAGCACTCTTAACCAGCATTAAAAATCA
ACAACATAAGGATGATCCTC

Downstream 100 bases:

>100_bases
GAGGAGAGGAAAATGCATAAAAATACAACGCAGACACCAGCGGGATCACACACTCACCTCGCCGGCGCATTTGATATCAG
AAATGTCATCGGAGCATTGA

Product: putative sodium:solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MDTALRLDATWVDYLLVALYFVFVLGIGWAAKARVSSSIDFFLSGRGLPAWVTGLAFVSANLGAVEIIGMSANGVQYGFQ
TMHYFWIGAVPAMVFLGIVMMPFYYGSKVRSVPEFMRRRFGSAAHLVNAVSFAVAQLLIAGVNLFLLAKVVNALLGWPLW
VALVLAAVIVLSYITLGGLSAAIYNEVLQFFVILAMLLPITIIGLNRVGGWQGLKEQVAIEHNFHTWPGVEISGFDNPVI
SVIGITFGLGFVLSFGYWTTNFVEVQRAMASESISAARKTPIIGAFPKMFVPFLVVLPGMVASVTVAELIGDNPAGKPND
AILYLMRDLLPNGLLGVAIAGLLASFMAGMAANISAFNTVISYDIWQTYVIKDREDDYYLKFGRLATVAATLIAVFTALL
AQNFGNIMDYLQTLFGFFNAPLFATFILGMFWKRMTPHAGWTGLVAGTASAIFYWYLATFTESSATLLNLPGQGTAFVAA
GIAFSVDILVSVIVTMFTQPKPDHELVGFVKSVTPKDHFEDHSEDGQPWYRRTVPLGMLCLILVIALNVIFA

Sequences:

>Translated_552_residues
MDTALRLDATWVDYLLVALYFVFVLGIGWAAKARVSSSIDFFLSGRGLPAWVTGLAFVSANLGAVEIIGMSANGVQYGFQ
TMHYFWIGAVPAMVFLGIVMMPFYYGSKVRSVPEFMRRRFGSAAHLVNAVSFAVAQLLIAGVNLFLLAKVVNALLGWPLW
VALVLAAVIVLSYITLGGLSAAIYNEVLQFFVILAMLLPITIIGLNRVGGWQGLKEQVAIEHNFHTWPGVEISGFDNPVI
SVIGITFGLGFVLSFGYWTTNFVEVQRAMASESISAARKTPIIGAFPKMFVPFLVVLPGMVASVTVAELIGDNPAGKPND
AILYLMRDLLPNGLLGVAIAGLLASFMAGMAANISAFNTVISYDIWQTYVIKDREDDYYLKFGRLATVAATLIAVFTALL
AQNFGNIMDYLQTLFGFFNAPLFATFILGMFWKRMTPHAGWTGLVAGTASAIFYWYLATFTESSATLLNLPGQGTAFVAA
GIAFSVDILVSVIVTMFTQPKPDHELVGFVKSVTPKDHFEDHSEDGQPWYRRTVPLGMLCLILVIALNVIFA
>Mature_552_residues
MDTALRLDATWVDYLLVALYFVFVLGIGWAAKARVSSSIDFFLSGRGLPAWVTGLAFVSANLGAVEIIGMSANGVQYGFQ
TMHYFWIGAVPAMVFLGIVMMPFYYGSKVRSVPEFMRRRFGSAAHLVNAVSFAVAQLLIAGVNLFLLAKVVNALLGWPLW
VALVLAAVIVLSYITLGGLSAAIYNEVLQFFVILAMLLPITIIGLNRVGGWQGLKEQVAIEHNFHTWPGVEISGFDNPVI
SVIGITFGLGFVLSFGYWTTNFVEVQRAMASESISAARKTPIIGAFPKMFVPFLVVLPGMVASVTVAELIGDNPAGKPND
AILYLMRDLLPNGLLGVAIAGLLASFMAGMAANISAFNTVISYDIWQTYVIKDREDDYYLKFGRLATVAATLIAVFTALL
AQNFGNIMDYLQTLFGFFNAPLFATFILGMFWKRMTPHAGWTGLVAGTASAIFYWYLATFTESSATLLNLPGQGTAFVAA
GIAFSVDILVSVIVTMFTQPKPDHELVGFVKSVTPKDHFEDHSEDGQPWYRRTVPLGMLCLILVIALNVIFA

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=557, Percent_Identity=25.4937163375224, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI17941285, Length=453, Percent_Identity=27.1523178807947, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI4507031, Length=567, Percent_Identity=24.5149911816578, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI110835708, Length=571, Percent_Identity=26.6199649737303, Blast_Score=150, Evalue=4e-36,
Organism=Homo sapiens, GI109659836, Length=463, Percent_Identity=25.4859611231102, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI4507033, Length=560, Percent_Identity=25.3571428571429, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI206597483, Length=565, Percent_Identity=25.1327433628319, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI109659839, Length=479, Percent_Identity=25.0521920668058, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI206597487, Length=589, Percent_Identity=24.2784380305603, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI256985183, Length=479, Percent_Identity=24.2171189979123, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI4507035, Length=430, Percent_Identity=24.1860465116279, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI157671931, Length=460, Percent_Identity=21.9565217391304, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI167466278, Length=472, Percent_Identity=24.1525423728814, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1790113, Length=518, Percent_Identity=23.9382239382239, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32566512, Length=362, Percent_Identity=22.9281767955801, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24645928, Length=451, Percent_Identity=23.7250554323725, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24651739, Length=466, Percent_Identity=20.8154506437768, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281362054, Length=458, Percent_Identity=24.235807860262, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281362052, Length=458, Percent_Identity=24.235807860262, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281362050, Length=458, Percent_Identity=24.235807860262, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24648056, Length=458, Percent_Identity=24.235807860262, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21356827, Length=458, Percent_Identity=24.235807860262, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24641117, Length=512, Percent_Identity=22.4609375, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281362918, Length=458, Percent_Identity=20.7423580786026, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24651741, Length=444, Percent_Identity=20.2702702702703, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI221459584, Length=452, Percent_Identity=21.6814159292035, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573698, Length=467, Percent_Identity=19.4860813704497, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24650192, Length=422, Percent_Identity=21.0900473933649, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221459582, Length=413, Percent_Identity=20.8232445520581, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221459588, Length=437, Percent_Identity=20.3661327231121, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221459586, Length=450, Percent_Identity=19.7777777777778, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 60075; Mature: 60075

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]