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The map label for this gene is sigW [H]

Identifier: 38233589

GI number: 38233589

Start: 964148

End: 964867

Strand: Direct

Name: sigW [H]

Synonym: DIP0994

Alternate gene names: 38233589

Gene position: 964148-964867 (Clockwise)

Preceding gene: 161598676

Following gene: 38233590

Centisome position: 38.74

GC content: 55.28

Gene sequence:

>720_bases
ATGCGTTGCCAGCCTTTTTGCAGGAACTTGGCTGGTTTTCCTCAGAACAGTCCGGCACAATCAACAACCATGACATACAC
GCACGGCTCCGCCCTCCCTAGCACCGACGACGTCACCATCGACGCCGACGTAGCCACCGAGGAATTGACTGGAACCGCAG
CTTTCGACGCAGGCGTAGGCGACATGCCTTCATGGGAAGAACTCGTTGCCCAACACGCCGATAGCGTTTACCGTCTAGCC
TTCCGCCTTTCCGGTAATCAGCACGACGCGGAAGACTTGACCCAAGAAACCTTCATGCGTGTATTCCGGTCGCTCAAAGG
CTATCAACCTGGAACCTTCGAAGGCTGGTTGCACCGTATCACCACCAACTTATTCCTCGACATGGTGCGACACCGTGCAA
AAATTCGTATGGAGGCCCTACCTGAAGATTACGAACGCGTTCCAGGTACGGACATGACGCCCGAGCAGGCGTACAACGTT
TCTAACTTGGATCCAGCGCTTCAAAAGGCTCTCGACGACCTCAGCCCTGACTTCCGCGTCGCCGTCGTGCTTTGCGACGT
CGTAGGCATGAGCTATGACGAAATCGCAGACACCTTAGGTGTGAAAATGGGCACCGTTCGTTCCCGAATCCACCGCGGAC
GTTCCCAATTGCGTGCACATTTGGAGAACCAAGCAACCAGCGATGAAGGTGCTCAACTCCTCCTAGCCACTGGGAGATAA

Upstream 100 bases:

>100_bases
TTGTGGTGGCGACATGGGCCCAACATCAAAGGTTGTGACGCCTGTTAACAGTGTGAATGCTGCAAACAGATCACCATAAG
GTCACAATCTGAGAACAATT

Downstream 100 bases:

>100_bases
AATCGGGGTACAGTTCGATGGCGGAGGTGACTATTACCAGATGAAAAAAGAACACTCCCCTAAAAACAAGGTGCGTCACT
TCGCATCAGTGGAGCATCTC

Product: RNA polymerase sigma factor SigE

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MRCQPFCRNLAGFPQNSPAQSTTMTYTHGSALPSTDDVTIDADVATEELTGTAAFDAGVGDMPSWEELVAQHADSVYRLA
FRLSGNQHDAEDLTQETFMRVFRSLKGYQPGTFEGWLHRITTNLFLDMVRHRAKIRMEALPEDYERVPGTDMTPEQAYNV
SNLDPALQKALDDLSPDFRVAVVLCDVVGMSYDEIADTLGVKMGTVRSRIHRGRSQLRAHLENQATSDEGAQLLLATGR

Sequences:

>Translated_239_residues
MRCQPFCRNLAGFPQNSPAQSTTMTYTHGSALPSTDDVTIDADVATEELTGTAAFDAGVGDMPSWEELVAQHADSVYRLA
FRLSGNQHDAEDLTQETFMRVFRSLKGYQPGTFEGWLHRITTNLFLDMVRHRAKIRMEALPEDYERVPGTDMTPEQAYNV
SNLDPALQKALDDLSPDFRVAVVLCDVVGMSYDEIADTLGVKMGTVRSRIHRGRSQLRAHLENQATSDEGAQLLLATGR
>Mature_239_residues
MRCQPFCRNLAGFPQNSPAQSTTMTYTHGSALPSTDDVTIDADVATEELTGTAAFDAGVGDMPSWEELVAQHADSVYRLA
FRLSGNQHDAEDLTQETFMRVFRSLKGYQPGTFEGWLHRITTNLFLDMVRHRAKIRMEALPEDYERVPGTDMTPEQAYNV
SNLDPALQKALDDLSPDFRVAVVLCDVVGMSYDEIADTLGVKMGTVRSRIHRGRSQLRAHLENQATSDEGAQLLLATGR

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=179, Percent_Identity=27.9329608938547, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 26526; Mature: 26526

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCQPFCRNLAGFPQNSPAQSTTMTYTHGSALPSTDDVTIDADVATEELTGTAAFDAGVG
CCCCHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCHHHHHHCCCHHHCCCCC
DMPSWEELVAQHADSVYRLAFRLSGNQHDAEDLTQETFMRVFRSLKGYQPGTFEGWLHRI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
TTNLFLDMVRHRAKIRMEALPEDYERVPGTDMTPEQAYNVSNLDPALQKALDDLSPDFRV
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCHHH
AVVLCDVVGMSYDEIADTLGVKMGTVRSRIHRGRSQLRAHLENQATSDEGAQLLLATGR
HHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
>Mature Secondary Structure
MRCQPFCRNLAGFPQNSPAQSTTMTYTHGSALPSTDDVTIDADVATEELTGTAAFDAGVG
CCCCHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCHHHHHHCCCHHHCCCCC
DMPSWEELVAQHADSVYRLAFRLSGNQHDAEDLTQETFMRVFRSLKGYQPGTFEGWLHRI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
TTNLFLDMVRHRAKIRMEALPEDYERVPGTDMTPEQAYNVSNLDPALQKALDDLSPDFRV
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCHHH
AVVLCDVVGMSYDEIADTLGVKMGTVRSRIHRGRSQLRAHLENQATSDEGAQLLLATGR
HHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]