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The map label for this gene is dapE [H]

Identifier: 38233577

GI number: 38233577

Start: 953662

End: 954759

Strand: Direct

Name: dapE [H]

Synonym: DIP0982

Alternate gene names: 38233577

Gene position: 953662-954759 (Clockwise)

Preceding gene: 38233571

Following gene: 38233578

Centisome position: 38.32

GC content: 55.56

Gene sequence:

>1098_bases
ATGCTCGATTTGACTACGAATCCCATTGACCTCACCCGCGCACTTGTTGATATAGAAAGCCCCTCCCATTACGAAAAGAA
CATAGCCGACGCCATCGAGCAAGCTCTTCATGCCATCGACAATGTTGAAGTGCTACGCCACGGCAATACTCTTGTTGCTC
GTACCCATCGAGGACTAGGAGAAAGAGTAATCCTCGCCGGCCACATCGACACCGTCCCAATAGCCGACAACGTTCCTAGC
CACATGGAAGGCGACGTAATGTTCGGCTGCGGCACCGTCGATATGAAATCGGGCATGGCTGTCTATCTTCATGCCTTTGC
CACCTTGGCTAACCACCCGGCGCTGGCGAAGGACTTGACCGTCGTCTGTTATGAGGGCGAGGAAGTCGCTAGTGAATACA
ACGGGCTGGGGCATGTGCAGGCAGCTCACCCCGACTGGTTAAGTGGCGATCTCGCCCTCCTAGGCGAGCCTTCCGGCGCT
GTGATCGAAGCTGGATGCCAAGGAACGATTCGTTTGCGCGTCACCGCCCATGGTGTGCGCGCACACTCGGCACGGTCGTG
GCTAGGAGACAACGCCATGCACAAATTAGCGCCAGTTATTACGAATATCGCACAGTACCACGCCCAAGAAATGCTTGTCG
ACGGCTGCCTCTACCACGAGGGCCTCAACATCGTGCATTGCGAATCTGGGGTTGCCACGAACACTATCCCCGATGAGGCC
TGGATGTTTGTTAACTTCCGTTTCGCACCTAATAGGAGTGTTGACGAAGCCCTAGCCCACATGCTGGAGGTGTTGGATCT
ACCCGAGGGGGTGACCTATGACATCGACGATGCTGTTCCAGGGGCACGTCCGGGTTTGGATCGTCCGGCAGCTGCCGCCC
TCCTAGAGGCGACAGGCGGAAAATTCCGCGCAAAGTACGGTTGGACGGATGTGTCGAGGTTTTCTGAGATTGGTGTTCCA
GCGGTGAACTTTGGTCCTGGGGATCCGGCATATTGCCATAAAAAAGACGAACAATGCCCAGTCAGCATGATTACCGAAGT
CTCTCGCACGCTGGTGCACTATCTCACGAGTACGAATTCCCAGACGACAGGAGCCTGA

Upstream 100 bases:

>100_bases
AGTGGCACCGAATTGACTCATAATTAAATACCTTAACGGAGCAGGCATGATTTGAAGAAGTTAGCGCTTCTTCTCCTAGA
GGCGCGGTATTGTCGATGCC

Downstream 100 bases:

>100_bases
TTGCTTTATGACTACTCAACCGCAACGCAATGAACGTCATCTGTGCGGGCCAGTGTTGGTGCGAGGCAAAAAGAATCAAT
CGCCAAGTACCTACGATCAA

Product: succinyl-diaminopimelate desuccinylase

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MLDLTTNPIDLTRALVDIESPSHYEKNIADAIEQALHAIDNVEVLRHGNTLVARTHRGLGERVILAGHIDTVPIADNVPS
HMEGDVMFGCGTVDMKSGMAVYLHAFATLANHPALAKDLTVVCYEGEEVASEYNGLGHVQAAHPDWLSGDLALLGEPSGA
VIEAGCQGTIRLRVTAHGVRAHSARSWLGDNAMHKLAPVITNIAQYHAQEMLVDGCLYHEGLNIVHCESGVATNTIPDEA
WMFVNFRFAPNRSVDEALAHMLEVLDLPEGVTYDIDDAVPGARPGLDRPAAAALLEATGGKFRAKYGWTDVSRFSEIGVP
AVNFGPGDPAYCHKKDEQCPVSMITEVSRTLVHYLTSTNSQTTGA

Sequences:

>Translated_365_residues
MLDLTTNPIDLTRALVDIESPSHYEKNIADAIEQALHAIDNVEVLRHGNTLVARTHRGLGERVILAGHIDTVPIADNVPS
HMEGDVMFGCGTVDMKSGMAVYLHAFATLANHPALAKDLTVVCYEGEEVASEYNGLGHVQAAHPDWLSGDLALLGEPSGA
VIEAGCQGTIRLRVTAHGVRAHSARSWLGDNAMHKLAPVITNIAQYHAQEMLVDGCLYHEGLNIVHCESGVATNTIPDEA
WMFVNFRFAPNRSVDEALAHMLEVLDLPEGVTYDIDDAVPGARPGLDRPAAAALLEATGGKFRAKYGWTDVSRFSEIGVP
AVNFGPGDPAYCHKKDEQCPVSMITEVSRTLVHYLTSTNSQTTGA
>Mature_365_residues
MLDLTTNPIDLTRALVDIESPSHYEKNIADAIEQALHAIDNVEVLRHGNTLVARTHRGLGERVILAGHIDTVPIADNVPS
HMEGDVMFGCGTVDMKSGMAVYLHAFATLANHPALAKDLTVVCYEGEEVASEYNGLGHVQAAHPDWLSGDLALLGEPSGA
VIEAGCQGTIRLRVTAHGVRAHSARSWLGDNAMHKLAPVITNIAQYHAQEMLVDGCLYHEGLNIVHCESGVATNTIPDEA
WMFVNFRFAPNRSVDEALAHMLEVLDLPEGVTYDIDDAVPGARPGLDRPAAAALLEATGGKFRAKYGWTDVSRFSEIGVP
AVNFGPGDPAYCHKKDEQCPVSMITEVSRTLVHYLTSTNSQTTGA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fifth step. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1788816, Length=283, Percent_Identity=27.5618374558304, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010174 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 39286; Mature: 39286

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLTTNPIDLTRALVDIESPSHYEKNIADAIEQALHAIDNVEVLRHGNTLVARTHRGLG
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHEECCCCEEEEECCCCCC
ERVILAGHIDTVPIADNVPSHMEGDVMFGCGTVDMKSGMAVYLHAFATLANHPALAKDLT
CEEEEEECCCCCCCCCCCCCCCCCCEEEECCCEECCCCHHHHHHHHHHHHCCCCCCCCCE
VVCYEGEEVASEYNGLGHVQAAHPDWLSGDLALLGEPSGAVIEAGCQGTIRLRVTAHGVR
EEEECCHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCEEECCCCEEEEEEEEECCCH
AHSARSWLGDNAMHKLAPVITNIAQYHAQEMLVDGCLYHEGLNIVHCESGVATNTIPDEA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCE
WMFVNFRFAPNRSVDEALAHMLEVLDLPEGVTYDIDDAVPGARPGLDRPAAAALLEATGG
EEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHCCC
KFRAKYGWTDVSRFSEIGVPAVNFGPGDPAYCHKKDEQCPVSMITEVSRTLVHYLTSTNS
CEEEECCCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
QTTGA
CCCCC
>Mature Secondary Structure
MLDLTTNPIDLTRALVDIESPSHYEKNIADAIEQALHAIDNVEVLRHGNTLVARTHRGLG
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHEECCCCEEEEECCCCCC
ERVILAGHIDTVPIADNVPSHMEGDVMFGCGTVDMKSGMAVYLHAFATLANHPALAKDLT
CEEEEEECCCCCCCCCCCCCCCCCCEEEECCCEECCCCHHHHHHHHHHHHCCCCCCCCCE
VVCYEGEEVASEYNGLGHVQAAHPDWLSGDLALLGEPSGAVIEAGCQGTIRLRVTAHGVR
EEEECCHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCCCEEECCCCEEEEEEEEECCCH
AHSARSWLGDNAMHKLAPVITNIAQYHAQEMLVDGCLYHEGLNIVHCESGVATNTIPDEA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCE
WMFVNFRFAPNRSVDEALAHMLEVLDLPEGVTYDIDDAVPGARPGLDRPAAAALLEATGG
EEEEEEEECCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHCCC
KFRAKYGWTDVSRFSEIGVPAVNFGPGDPAYCHKKDEQCPVSMITEVSRTLVHYLTSTNS
CEEEECCCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
QTTGA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7881553; 12948626; 7592354 [H]