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The map label for this gene is arsC [H]

Identifier: 38233561

GI number: 38233561

Start: 937977

End: 938321

Strand: Reverse

Name: arsC [H]

Synonym: DIP0965

Alternate gene names: 38233561

Gene position: 938321-937977 (Counterclockwise)

Preceding gene: 38233562

Following gene: 38233560

Centisome position: 37.7

GC content: 56.23

Gene sequence:

>345_bases
ATGATTACCGTCTATCACAACCCCCGCTGCTCCACCTCGCGCAAAGCCTTGGAGTACATAGAACAACACAGCGACGACGA
GGTGACCATCATCCGCTACCTCGACGCCCCTCCTAGTGAACAAGAGCTGCGCACTTTGCTTGCCGACGCCCACCTCAGCC
CGCACGACGCAATCCGCACCAAAGAAGCCGAATACAAAGAACTCGGACTCAGCTCCACCACCCCCGAATCAGAGCTAATC
AAGGCCATGGTCACCCACCCACGCCTCATTCAGCGCCCAATTGTGGCAACATGCAAGGGAACGCGGATCGCCCGACCAAC
CGAAATTCTGAAAGAAATTCTCTAG

Upstream 100 bases:

>100_bases
TCGACGGCATCACACGCCATAACGACGACCCCATGGCATGGCTCGCCGCTATGGGATACCCACTAACATGGGCAAAAAAC
ATCACGCTTAAGGAGGCCGA

Downstream 100 bases:

>100_bases
ATGAAGAAACTTCGTACCCTAGCCGTAACCCTGACCGCAATCGCAGCATCAACCATGGCGACCATGCCAGCACAAGCAGT
GATTAGTCCGACACCGTCAC

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MITVYHNPRCSTSRKALEYIEQHSDDEVTIIRYLDAPPSEQELRTLLADAHLSPHDAIRTKEAEYKELGLSSTTPESELI
KAMVTHPRLIQRPIVATCKGTRIARPTEILKEIL

Sequences:

>Translated_114_residues
MITVYHNPRCSTSRKALEYIEQHSDDEVTIIRYLDAPPSEQELRTLLADAHLSPHDAIRTKEAEYKELGLSSTTPESELI
KAMVTHPRLIQRPIVATCKGTRIARPTEILKEIL
>Mature_114_residues
MITVYHNPRCSTSRKALEYIEQHSDDEVTIIRYLDAPPSEQELRTLLADAHLSPHDAIRTKEAEYKELGLSSTTPESELI
KAMVTHPRLIQRPIVATCKGTRIARPTEILKEIL

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=114, Percent_Identity=48.2456140350877, Blast_Score=99, Evalue=9e-23,
Organism=Escherichia coli, GI1788841, Length=115, Percent_Identity=40.8695652173913, Blast_Score=80, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 12962; Mature: 12962

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVYHNPRCSTSRKALEYIEQHSDDEVTIIRYLDAPPSEQELRTLLADAHLSPHDAIRT
CEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHC
KEAEYKELGLSSTTPESELIKAMVTHPRLIQRPIVATCKGTRIARPTEILKEIL
CCHHHHHCCCCCCCCHHHHHHHHHHCHHHHHCCHHHHCCCCCCCCHHHHHHHHC
>Mature Secondary Structure
MITVYHNPRCSTSRKALEYIEQHSDDEVTIIRYLDAPPSEQELRTLLADAHLSPHDAIRT
CEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHC
KEAEYKELGLSSTTPESELIKAMVTHPRLIQRPIVATCKGTRIARPTEILKEIL
CCHHHHHCCCCCCCCHHHHHHHHHHCHHHHHCCHHHHCCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]