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The map label for this gene is perM [C]

Identifier: 38233541

GI number: 38233541

Start: 916085

End: 917503

Strand: Reverse

Name: perM [C]

Synonym: DIP0945

Alternate gene names: 38233541

Gene position: 917503-916085 (Counterclockwise)

Preceding gene: 38233542

Following gene: 38233540

Centisome position: 36.87

GC content: 55.46

Gene sequence:

>1419_bases
GTGACTTCCGACATTCCCACCCCAGAAGAGTCCGCACCAGATCGTGTGACACCACGCACCGAACACGCCGGATCTTCTAC
CGAGGCAACTGATGTCTTTGAGGCCATGTCTCCTCACGACGACCACGCCCGCATCGACCGCTCGGAAGTCATAGCACACG
GCGTTAAAGTTCTCTCCACATGGTGTATCCGCATTCTCATCATTGCAGCCACCGCATTTGCTACCTGGTATCTACTCAAG
CAGGTGTGGCGCGGAGTACTGCCGGTCATTCTCGCACTGATCGTCTGCACCGTGCTGTGGCCGCCAACAATCTGGATGCG
TCGCAAAGGCATCCCTAGCGGCATCGCCGCGCTCATAAGCATTTTGGCCAGCTTTGGATTCTTTGGGTTCCTCATCTGGA
TTATCGCCCCAGATGTAGGACGGCAATCTCAAACCTTGTATTTCCAAGCATTCGAGGGAATCCAAAAGATCCAACTGTGG
TTGCAAGGACCACCACTTAGCCTCGATTCTGAAGAGCTGAACGACCGCATCAATGCCGCCGCCGGATGGTTCCAAAGTAA
AAGCGGCACCATCGCGGGTGAAATCTTCTCCGGACTGGGAGTGGCAACATCCGTCCTCGTTACCCTCGGTGTGGTCCTCG
TTTTAACCTTCTTCTTCCTCAAAGACGGCGAAAAATTCCTGCCTTGGGTACGTGGGATCGTCGGAAAGCGCGCAGGCTGG
CACCTCACGGAGCTCCTCGCACGATCGTGGATCACCCTATGCGGATTCGTACGTGCCCAAGCCCTCGTTTCGCTTGTCGA
CGCCATCGCGATCGGCGGCGGACTCCTCCTCCTAGGCGTCCCCATGGCACTCGCACTCGCAGTGCTCACCTTCATCGCCG
GATTCATCCCCATCGTCGGAGCCTTTGTCGCAGGAACTCTAGCCGTCCTCGTAGCACTCGTGTCCTTAGGCCTGACCAAA
GCCGTGATCACACTCATCATCGTGCTTGCAGTTCAACAACTCGAAGGCAATGTGCTTTCCCCCATCCTGCAATCTCGCGC
CATGAACCTGCACCCCGTGGTCGTCTTGGTATCCGTGACCCTCGGTGGCAGCCTCTTTGGCATCGTCGGAGCCTTCCTCG
CAGTCCCCACCGCAGCCATGATCGCCGTCTTATTCCGCTACCTCCAAGACATGACAGCGCTACGAGCTGGCGAAAAAACC
GCCGACGACATCAAATTTGTTACTCGCGCAGGCTCCATCACCGGAAAATTCGGCGAACAGAAAAACCAAGAACTAATCGC
AGCGAAACTAAAATCCCAAGAACAACAAGCCTCTCCTCCTAGAGAATCAGACACGCAACCAGATGTTGATCACCCCCTTG
TTGTCCAAGGGATAAAAGCGAAAATCAGCGACCTAACACATCTGTTCCACAAACCCTGA

Upstream 100 bases:

>100_bases
ACACCTCTTAACACCCACGGGGGATGGCATAGAAAAAAGACATCCCATCATTGGGCATTGCTCTCCACGCTAACGCATGT
GATGAGGCACAATAATTGCT

Downstream 100 bases:

>100_bases
TTTTTAGGACACACCCCCTAGGCCAAAGTTCCCAACCACAGATCCCCTTGAGTAGGATAAACATCCGTGCAGAACAAGAC
AGAACATAAACGCCACAGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MTSDIPTPEESAPDRVTPRTEHAGSSTEATDVFEAMSPHDDHARIDRSEVIAHGVKVLSTWCIRILIIAATAFATWYLLK
QVWRGVLPVILALIVCTVLWPPTIWMRRKGIPSGIAALISILASFGFFGFLIWIIAPDVGRQSQTLYFQAFEGIQKIQLW
LQGPPLSLDSEELNDRINAAAGWFQSKSGTIAGEIFSGLGVATSVLVTLGVVLVLTFFFLKDGEKFLPWVRGIVGKRAGW
HLTELLARSWITLCGFVRAQALVSLVDAIAIGGGLLLLGVPMALALAVLTFIAGFIPIVGAFVAGTLAVLVALVSLGLTK
AVITLIIVLAVQQLEGNVLSPILQSRAMNLHPVVVLVSVTLGGSLFGIVGAFLAVPTAAMIAVLFRYLQDMTALRAGEKT
ADDIKFVTRAGSITGKFGEQKNQELIAAKLKSQEQQASPPRESDTQPDVDHPLVVQGIKAKISDLTHLFHKP

Sequences:

>Translated_472_residues
MTSDIPTPEESAPDRVTPRTEHAGSSTEATDVFEAMSPHDDHARIDRSEVIAHGVKVLSTWCIRILIIAATAFATWYLLK
QVWRGVLPVILALIVCTVLWPPTIWMRRKGIPSGIAALISILASFGFFGFLIWIIAPDVGRQSQTLYFQAFEGIQKIQLW
LQGPPLSLDSEELNDRINAAAGWFQSKSGTIAGEIFSGLGVATSVLVTLGVVLVLTFFFLKDGEKFLPWVRGIVGKRAGW
HLTELLARSWITLCGFVRAQALVSLVDAIAIGGGLLLLGVPMALALAVLTFIAGFIPIVGAFVAGTLAVLVALVSLGLTK
AVITLIIVLAVQQLEGNVLSPILQSRAMNLHPVVVLVSVTLGGSLFGIVGAFLAVPTAAMIAVLFRYLQDMTALRAGEKT
ADDIKFVTRAGSITGKFGEQKNQELIAAKLKSQEQQASPPRESDTQPDVDHPLVVQGIKAKISDLTHLFHKP
>Mature_471_residues
TSDIPTPEESAPDRVTPRTEHAGSSTEATDVFEAMSPHDDHARIDRSEVIAHGVKVLSTWCIRILIIAATAFATWYLLKQ
VWRGVLPVILALIVCTVLWPPTIWMRRKGIPSGIAALISILASFGFFGFLIWIIAPDVGRQSQTLYFQAFEGIQKIQLWL
QGPPLSLDSEELNDRINAAAGWFQSKSGTIAGEIFSGLGVATSVLVTLGVVLVLTFFFLKDGEKFLPWVRGIVGKRAGWH
LTELLARSWITLCGFVRAQALVSLVDAIAIGGGLLLLGVPMALALAVLTFIAGFIPIVGAFVAGTLAVLVALVSLGLTKA
VITLIIVLAVQQLEGNVLSPILQSRAMNLHPVVVLVSVTLGGSLFGIVGAFLAVPTAAMIAVLFRYLQDMTALRAGEKTA
DDIKFVTRAGSITGKFGEQKNQELIAAKLKSQEQQASPPRESDTQPDVDHPLVVQGIKAKISDLTHLFHKP

Specific function: Unknown

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1788838, Length=304, Percent_Identity=30.2631578947368, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87082271, Length=302, Percent_Identity=23.841059602649, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 50773; Mature: 50642

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDIPTPEESAPDRVTPRTEHAGSSTEATDVFEAMSPHDDHARIDRSEVIAHGVKVLST
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHH
WCIRILIIAATAFATWYLLKQVWRGVLPVILALIVCTVLWPPTIWMRRKGIPSGIAALIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHH
ILASFGFFGFLIWIIAPDVGRQSQTLYFQAFEGIQKIQLWLQGPPLSLDSEELNDRINAA
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AGWFQSKSGTIAGEIFSGLGVATSVLVTLGVVLVLTFFFLKDGEKFLPWVRGIVGKRAGW
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
HLTELLARSWITLCGFVRAQALVSLVDAIAIGGGLLLLGVPMALALAVLTFIAGFIPIVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFVAGTLAVLVALVSLGLTKAVITLIIVLAVQQLEGNVLSPILQSRAMNLHPVVVLVSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHH
LGGSLFGIVGAFLAVPTAAMIAVLFRYLQDMTALRAGEKTADDIKFVTRAGSITGKFGEQ
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCH
KNQELIAAKLKSQEQQASPPRESDTQPDVDHPLVVQGIKAKISDLTHLFHKP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSDIPTPEESAPDRVTPRTEHAGSSTEATDVFEAMSPHDDHARIDRSEVIAHGVKVLST
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]