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The map label for this gene is yknU [H]

Identifier: 38233504

GI number: 38233504

Start: 879104

End: 880714

Strand: Direct

Name: yknU [H]

Synonym: DIP0908

Alternate gene names: 38233504

Gene position: 879104-880714 (Clockwise)

Preceding gene: 38233503

Following gene: 38233505

Centisome position: 35.32

GC content: 56.73

Gene sequence:

>1611_bases
ATGCAATGGCGTCTTTTTACTCGGCCGAATCAGGTTCCTCCACGCATGGTGACGTGGTCGTGGCTTGCGCCGGCCACCCC
CTCGGTTAGTCGTGACAGTTTGCCACCTCGTGGATGGGGATCGGGGCCGCGGGCAGCATGGTCAATATTGTGGATGTACC
CGTGGGTGAGTATCTACACGGTTGTAGTGATGATCGCTTCGTCAATGGCGTCGGTGGGAGTGTCGGCGGTGATTGGCCGC
GCGGTTGACGGCACGCTGGGCAGCGGAACGCTTGCCGACGCTCTAGCTCCGATGGCTGGTGTCGCAGCATTTTTATTGAT
GGTGTACCTGTGTCAGTCCACCGCTGATGCAGTGACTGAGATCGCTATTCAGCGCGGTGTTCACCATGTGCGTTTCGCGC
TGGTGCGACGTCTTTCTACCTCTCATCCGAGCGATCTCACCCCAGGTCAGCTGTTAAATACCGTGGACGAGGATGTCCAA
CAGTTGGTCAGCGTGAAGCAGAATTTCAGTTTTCCCGTGGCCATGTTTGCCTATCTTTTGGGCACCGTGGTGGCCATTGC
GCAGTTTTCGCTTCCACTGGGCGCGGCCGTGCTAGGAGGTGGCGTGGCCACGGCGGCAGTGTCTTATTTCACGGGTAAGG
CGATTACAAAAGTTTCTGGTCAGCGGCGCAATATGGAGTCCGAGTCGGTGTCGTTGGCTACAGATTTAGCCCAAGGTGCG
CGCGTGGTTCGAGGTCTGGGCGCGGTCGATGCCAGTGAACAGCGTTTCGACGCTGCCACTGCGGCCGCGTTGGCGGTCAT
GCTTCAAGACGCGAAGGTGTCTTCCATTACCACCTTGATTCGCCAAATGATCCCGATGATTTTTACTCTCGCGGTGCTGT
CCTACGGCGGATGGCTCACGATGCATGGGGACATTTCTTCGGGACAGTTTCTCACAGTAACGCTGCTTGCCGTTCCAGCA
CTTTCGATTACGGGATATTCGCTGGGATTTCTTACCGACTTCTGGGCACGCGCGGTTGCCAGCGGACGTCGTATTAACAA
GCTGTCGGAGCAACTGGCCCAACCTCGCCACGGGGAAGCACAGCGCAGTATCCACGTTGACTCTGGACTCACAGTTTGGG
CGCCTACGACTCCTCGTGCACGAGAAACAGTGCACGAACTTACGGAATACCTCGTCCAGCACCGTGGAGCTATTGCTGCA
CCGCACGCTGTCAGTGTTTTCCAAGGCACGCTTACCGACAACATCGATCCGTTACAGCAGCTTTCGTCTGAAGAAATAGA
GCAGGTGATTGAGGCTAGTTGTAGTACCGATGTAGTGAAACGCCTCGGTGGCGTTCCCCACGGGGGAGTGCCGAGTGCCC
TTATCGGAGAATCCGGCCTCAACTTGTCTGGCGGCCAACGCCAACGTGTCGCCCTAGCGCGGGTATTGGGGATGAATCCA
GAGATTTTGATTCTGGATGAGCCCACAACGGGGCTAGATGCTGTGACTCTTGATCGCGTGACGGCACATGTGAAGGAGTT
TCGTCAAGGAAAGACCACGATTGTGATTACGACTTCGCGGGCGTGGGCAGCGGTGGCTGACACGGTTATTGATGATAAGG
AGCTGGCATAA

Upstream 100 bases:

>100_bases
TTTGATGCGAATGCCCAAGCTTTTACCCGTGGGGAAACGATGCCAACGGAGGTGAATCCGCACTTAGGTTATTAGGCGCA
GGTGTGTACGGTTAACTCTT

Downstream 100 bases:

>100_bases
ATGGCTACGGGTACTGAGTCTGCGCTGCTGCAGCCGGCGTCGATACGCGAAATCGGTGCCTTTTTGGCTACCTTGCCGTC
TCGTCCGAGGTTGACATGGT

Product: ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MQWRLFTRPNQVPPRMVTWSWLAPATPSVSRDSLPPRGWGSGPRAAWSILWMYPWVSIYTVVVMIASSMASVGVSAVIGR
AVDGTLGSGTLADALAPMAGVAAFLLMVYLCQSTADAVTEIAIQRGVHHVRFALVRRLSTSHPSDLTPGQLLNTVDEDVQ
QLVSVKQNFSFPVAMFAYLLGTVVAIAQFSLPLGAAVLGGGVATAAVSYFTGKAITKVSGQRRNMESESVSLATDLAQGA
RVVRGLGAVDASEQRFDAATAAALAVMLQDAKVSSITTLIRQMIPMIFTLAVLSYGGWLTMHGDISSGQFLTVTLLAVPA
LSITGYSLGFLTDFWARAVASGRRINKLSEQLAQPRHGEAQRSIHVDSGLTVWAPTTPRARETVHELTEYLVQHRGAIAA
PHAVSVFQGTLTDNIDPLQQLSSEEIEQVIEASCSTDVVKRLGGVPHGGVPSALIGESGLNLSGGQRQRVALARVLGMNP
EILILDEPTTGLDAVTLDRVTAHVKEFRQGKTTIVITTSRAWAAVADTVIDDKELA

Sequences:

>Translated_536_residues
MQWRLFTRPNQVPPRMVTWSWLAPATPSVSRDSLPPRGWGSGPRAAWSILWMYPWVSIYTVVVMIASSMASVGVSAVIGR
AVDGTLGSGTLADALAPMAGVAAFLLMVYLCQSTADAVTEIAIQRGVHHVRFALVRRLSTSHPSDLTPGQLLNTVDEDVQ
QLVSVKQNFSFPVAMFAYLLGTVVAIAQFSLPLGAAVLGGGVATAAVSYFTGKAITKVSGQRRNMESESVSLATDLAQGA
RVVRGLGAVDASEQRFDAATAAALAVMLQDAKVSSITTLIRQMIPMIFTLAVLSYGGWLTMHGDISSGQFLTVTLLAVPA
LSITGYSLGFLTDFWARAVASGRRINKLSEQLAQPRHGEAQRSIHVDSGLTVWAPTTPRARETVHELTEYLVQHRGAIAA
PHAVSVFQGTLTDNIDPLQQLSSEEIEQVIEASCSTDVVKRLGGVPHGGVPSALIGESGLNLSGGQRQRVALARVLGMNP
EILILDEPTTGLDAVTLDRVTAHVKEFRQGKTTIVITTSRAWAAVADTVIDDKELA
>Mature_536_residues
MQWRLFTRPNQVPPRMVTWSWLAPATPSVSRDSLPPRGWGSGPRAAWSILWMYPWVSIYTVVVMIASSMASVGVSAVIGR
AVDGTLGSGTLADALAPMAGVAAFLLMVYLCQSTADAVTEIAIQRGVHHVRFALVRRLSTSHPSDLTPGQLLNTVDEDVQ
QLVSVKQNFSFPVAMFAYLLGTVVAIAQFSLPLGAAVLGGGVATAAVSYFTGKAITKVSGQRRNMESESVSLATDLAQGA
RVVRGLGAVDASEQRFDAATAAALAVMLQDAKVSSITTLIRQMIPMIFTLAVLSYGGWLTMHGDISSGQFLTVTLLAVPA
LSITGYSLGFLTDFWARAVASGRRINKLSEQLAQPRHGEAQRSIHVDSGLTVWAPTTPRARETVHELTEYLVQHRGAIAA
PHAVSVFQGTLTDNIDPLQQLSSEEIEQVIEASCSTDVVKRLGGVPHGGVPSALIGESGLNLSGGQRQRVALARVLGMNP
EILILDEPTTGLDAVTLDRVTAHVKEFRQGKTTIVITTSRAWAAVADTVIDDKELA

Specific function: Involved In Lipid A Export And Possibly Also In Glycerophospholipid Export And For Biogenesis Of The Outer Membrane. Transmembrane Domains (Tmd) Form A Pore In The Inner Membrane And The ATP-Binding Domain (Nbd) Is Responsible For Energy Generation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42741659, Length=130, Percent_Identity=36.9230769230769, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI255708477, Length=175, Percent_Identity=30.2857142857143, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI148612844, Length=130, Percent_Identity=33.8461538461538, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI9961250, Length=125, Percent_Identity=35.2, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI4505771, Length=125, Percent_Identity=35.2, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI9961252, Length=125, Percent_Identity=35.2, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI171184400, Length=115, Percent_Identity=35.6521739130435, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1787143, Length=150, Percent_Identity=34, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786653, Length=111, Percent_Identity=35.1351351351351, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790162, Length=70, Percent_Identity=38.5714285714286, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17558664, Length=143, Percent_Identity=33.5664335664336, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193202349, Length=114, Percent_Identity=38.5964912280702, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=132, Percent_Identity=35.6060606060606, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=137, Percent_Identity=36.4963503649635, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17569145, Length=149, Percent_Identity=33.5570469798658, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115535101, Length=130, Percent_Identity=35.3846153846154, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17567265, Length=112, Percent_Identity=36.6071428571429, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320339, Length=133, Percent_Identity=32.3308270676692, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397593, Length=128, Percent_Identity=37.5, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI85726357, Length=126, Percent_Identity=35.7142857142857, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24659289, Length=113, Percent_Identity=37.1681415929204, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357907, Length=137, Percent_Identity=34.3065693430657, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363262, Length=126, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24653245, Length=126, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 57110; Mature: 57110

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQWRLFTRPNQVPPRMVTWSWLAPATPSVSRDSLPPRGWGSGPRAAWSILWMYPWVSIYT
CCCEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VVVMIASSMASVGVSAVIGRAVDGTLGSGTLADALAPMAGVAAFLLMVYLCQSTADAVTE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAIQRGVHHVRFALVRRLSTSHPSDLTPGQLLNTVDEDVQQLVSVKQNFSFPVAMFAYLL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GTVVAIAQFSLPLGAAVLGGGVATAAVSYFTGKAITKVSGQRRNMESESVSLATDLAQGA
HHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHCHHHHHHCCHHCCCCHHHHHHHHHHHHHH
RVVRGLGAVDASEQRFDAATAAALAVMLQDAKVSSITTLIRQMIPMIFTLAVLSYGGWLT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
MHGDISSGQFLTVTLLAVPALSITGYSLGFLTDFWARAVASGRRINKLSEQLAQPRHGEA
EECCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
QRSIHVDSGLTVWAPTTPRARETVHELTEYLVQHRGAIAAPHAVSVFQGTLTDNIDPLQQ
CCEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHH
LSSEEIEQVIEASCSTDVVKRLGGVPHGGVPSALIGESGLNLSGGQRQRVALARVLGMNP
HHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCCC
EILILDEPTTGLDAVTLDRVTAHVKEFRQGKTTIVITTSRAWAAVADTVIDDKELA
CEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]