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The map label for this gene is gap [H]

Identifier: 38233488

GI number: 38233488

Start: 862908

End: 864338

Strand: Reverse

Name: gap [H]

Synonym: DIP0892

Alternate gene names: 38233488

Gene position: 864338-862908 (Counterclockwise)

Preceding gene: 38233491

Following gene: 38233487

Centisome position: 34.73

GC content: 54.72

Gene sequence:

>1431_bases
ATGGCTCAGGACTGGAACGACAAGATCGAATCCGCCCAAAAGATGCTCCCCCTGATTGCACAGCTTCACAACAACAACAA
TGTTGTGGTGTCTGTTTTCGGCCGTTTGCTTATCAATGTCACCGATATCGACATTGTGAAGGCGCACCGCTACTCCCGCT
TAGCCACGGAAACCGAACTGTCCCCTGCCGATACTCTCCCAGTACTCGAGGCACTTCACTCTATTAATGTTGGCCCAGCC
TCTATCGACTTGGGCCGTTTGGTAGAGCTACACCGCAGCAAGGGCGGCGACCTTACACAGTTCCTCACGGAGGAGCTGAG
TAATGTGATTGATACGCGTCCTGCCGAAAACCCAGCAGACGTCGTTCTTTATGGGTTTGGCCGAATCGGCCGCTTGCTCG
CCCGCATCCTGATCGCCCGCGAGGCTGCGTATGGTGGCGTGCGCCTTCGCGCCGTCGTCGTCCGCAAGAACGGTGACCAA
GACCTACAAAAGCGTGCGTCGTTGCTGCGCCGCGACTCGGTACATGGTGCTTTTAACGGCACGATCACCGTCGACGAGGA
AAATAACATCATTTGGGCAAATGGCACCAAGATTCAGATTATTTATTCCAATGACCCTGCCACCGTCGATTACACCGAAT
ACGGCATTAACGACGCCATCGTGGTGGACAACACCGGCCGCTGGCGCGATCGTGAGGGACTTTCCCAGCACTTGAAGTCT
AAGGGCGTCAAGCGTGTTGTCCTCACTGCTCCAGGCAAGGGCGATTTGAAGAACATCGTCTACGGCATCAACCACGGCGA
TATTACCGATGCTGATAGCATCGTCACTGCGGCATCCTGCACCACCAACGGCATTACCCCAACACTGAAGGTCATCAACG
ATCACTACGGTATCGAGTACGGTCACGTTGAAACCGTCCACTCCTTTACTAATGACCAGAACTTGATCGACAACTTCCAC
AAGGGTGCTCGTCGTGGTCGTGCCGCCGGCCTGAATATGGTTCTTACGGAAACAGGTGCTGCAAAGGCGGTGTCCAAGGC
ACTTCCGGAGCTCGAAGGAAAACTCACCGGCAATGCCATTCGCGTCCCTACCCCTGATGTGTCGATGGCTGTTTTGAACC
TGACGCTTGAAAAGGAAGTCACCCGTGAGGAAGTAAATACTCTCATGGATAAGGTGGCACTACACTCCGACCTGCGCCAG
CAGATTTCCTACATTCAGTCGCCCGAGGTTGTTTCCTCCGATTTCGTTGGCACGACGCACGCAGGCATTGTCGACGGCCT
CGCCACCATTGCTAACGGCAAGCACTTGGTTCTCTACGTGTGGTACGACAACGAGTTTGGCTATTCCAACCAGGTTATCC
GCATCGTCGAGCATGTTGCGGGCGCACGCCCAACAGTACTGCCCGAGCGTATCGCTTCTGCAGAGCTGTAA

Upstream 100 bases:

>100_bases
TCACTAGCATTGTGGGGGTATGTAAGCGCGTACCACTGCCCTACGCATGCTTCGATGTACTCCCCCTTTGTAAAACCGAC
ATAAGGAACACACGATTCTC

Downstream 100 bases:

>100_bases
CAGCATTAAGTAAGTAACACTGAAGCCTTCTTTTCGCCATGGCAAGGATCAACGACGAAAAGAAGGCTTCAGTGTTTTTA
GAAAGAGCGTATTTTCTTCA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MAQDWNDKIESAQKMLPLIAQLHNNNNVVVSVFGRLLINVTDIDIVKAHRYSRLATETELSPADTLPVLEALHSINVGPA
SIDLGRLVELHRSKGGDLTQFLTEELSNVIDTRPAENPADVVLYGFGRIGRLLARILIAREAAYGGVRLRAVVVRKNGDQ
DLQKRASLLRRDSVHGAFNGTITVDEENNIIWANGTKIQIIYSNDPATVDYTEYGINDAIVVDNTGRWRDREGLSQHLKS
KGVKRVVLTAPGKGDLKNIVYGINHGDITDADSIVTAASCTTNGITPTLKVINDHYGIEYGHVETVHSFTNDQNLIDNFH
KGARRGRAAGLNMVLTETGAAKAVSKALPELEGKLTGNAIRVPTPDVSMAVLNLTLEKEVTREEVNTLMDKVALHSDLRQ
QISYIQSPEVVSSDFVGTTHAGIVDGLATIANGKHLVLYVWYDNEFGYSNQVIRIVEHVAGARPTVLPERIASAEL

Sequences:

>Translated_476_residues
MAQDWNDKIESAQKMLPLIAQLHNNNNVVVSVFGRLLINVTDIDIVKAHRYSRLATETELSPADTLPVLEALHSINVGPA
SIDLGRLVELHRSKGGDLTQFLTEELSNVIDTRPAENPADVVLYGFGRIGRLLARILIAREAAYGGVRLRAVVVRKNGDQ
DLQKRASLLRRDSVHGAFNGTITVDEENNIIWANGTKIQIIYSNDPATVDYTEYGINDAIVVDNTGRWRDREGLSQHLKS
KGVKRVVLTAPGKGDLKNIVYGINHGDITDADSIVTAASCTTNGITPTLKVINDHYGIEYGHVETVHSFTNDQNLIDNFH
KGARRGRAAGLNMVLTETGAAKAVSKALPELEGKLTGNAIRVPTPDVSMAVLNLTLEKEVTREEVNTLMDKVALHSDLRQ
QISYIQSPEVVSSDFVGTTHAGIVDGLATIANGKHLVLYVWYDNEFGYSNQVIRIVEHVAGARPTVLPERIASAEL
>Mature_475_residues
AQDWNDKIESAQKMLPLIAQLHNNNNVVVSVFGRLLINVTDIDIVKAHRYSRLATETELSPADTLPVLEALHSINVGPAS
IDLGRLVELHRSKGGDLTQFLTEELSNVIDTRPAENPADVVLYGFGRIGRLLARILIAREAAYGGVRLRAVVVRKNGDQD
LQKRASLLRRDSVHGAFNGTITVDEENNIIWANGTKIQIIYSNDPATVDYTEYGINDAIVVDNTGRWRDREGLSQHLKSK
GVKRVVLTAPGKGDLKNIVYGINHGDITDADSIVTAASCTTNGITPTLKVINDHYGIEYGHVETVHSFTNDQNLIDNFHK
GARRGRAAGLNMVLTETGAAKAVSKALPELEGKLTGNAIRVPTPDVSMAVLNLTLEKEVTREEVNTLMDKVALHSDLRQQ
ISYIQSPEVVSSDFVGTTHAGIVDGLATIANGKHLVLYVWYDNEFGYSNQVIRIVEHVAGARPTVLPERIASAEL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=39.9408284023669, Blast_Score=205, Evalue=9e-53,
Organism=Homo sapiens, GI7657116, Length=338, Percent_Identity=36.9822485207101, Blast_Score=192, Evalue=5e-49,
Organism=Escherichia coli, GI1788079, Length=338, Percent_Identity=39.9408284023669, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=35.2238805970149, Blast_Score=190, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17534677, Length=349, Percent_Identity=39.2550143266476, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17534679, Length=349, Percent_Identity=38.9684813753582, Blast_Score=214, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI17568413, Length=342, Percent_Identity=39.1812865497076, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI32566163, Length=342, Percent_Identity=39.1812865497076, Blast_Score=210, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6322409, Length=344, Percent_Identity=40.9883720930233, Blast_Score=226, Evalue=9e-60,
Organism=Saccharomyces cerevisiae, GI6321631, Length=344, Percent_Identity=40.6976744186046, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6322468, Length=344, Percent_Identity=40.6976744186046, Blast_Score=221, Evalue=2e-58,
Organism=Drosophila melanogaster, GI85725000, Length=337, Percent_Identity=39.1691394658754, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI22023983, Length=337, Percent_Identity=39.1691394658754, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI19922412, Length=334, Percent_Identity=37.7245508982036, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17933600, Length=337, Percent_Identity=38.5756676557863, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI18110149, Length=337, Percent_Identity=38.5756676557863, Blast_Score=200, Evalue=2e-51,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 52049; Mature: 51917

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQDWNDKIESAQKMLPLIAQLHNNNNVVVSVFGRLLINVTDIDIVKAHRYSRLATETEL
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHEEECCCHHHHHHHHHHHHHHCCC
SPADTLPVLEALHSINVGPASIDLGRLVELHRSKGGDLTQFLTEELSNVIDTRPAENPAD
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
VVLYGFGRIGRLLARILIAREAAYGGVRLRAVVVRKNGDQDLQKRASLLRRDSVHGAFNG
EEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCC
TITVDEENNIIWANGTKIQIIYSNDPATVDYTEYGINDAIVVDNTGRWRDREGLSQHLKS
EEEEECCCCEEEECCCEEEEEECCCCCEEEEHHCCCCCEEEECCCCCCCCHHHHHHHHHH
KGVKRVVLTAPGKGDLKNIVYGINHGDITDADSIVTAASCTTNGITPTLKVINDHYGIEY
CCCEEEEEECCCCCCCCHHEEECCCCCCCCCHHHEEEECCCCCCCCHHHEEEHHCCCCCC
GHVETVHSFTNDQNLIDNFHKGARRGRAAGLNMVLTETGAAKAVSKALPELEGKLTGNAI
CCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEE
RVPTPDVSMAVLNLTLEKEVTREEVNTLMDKVALHSDLRQQISYIQSPEVVSSDFVGTTH
ECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCH
AGIVDGLATIANGKHLVLYVWYDNEFGYSNQVIRIVEHVAGARPTVLPERIASAEL
HHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
AQDWNDKIESAQKMLPLIAQLHNNNNVVVSVFGRLLINVTDIDIVKAHRYSRLATETEL
CCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHEEECCCHHHHHHHHHHHHHHCCC
SPADTLPVLEALHSINVGPASIDLGRLVELHRSKGGDLTQFLTEELSNVIDTRPAENPAD
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
VVLYGFGRIGRLLARILIAREAAYGGVRLRAVVVRKNGDQDLQKRASLLRRDSVHGAFNG
EEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCC
TITVDEENNIIWANGTKIQIIYSNDPATVDYTEYGINDAIVVDNTGRWRDREGLSQHLKS
EEEEECCCCEEEECCCEEEEEECCCCCEEEEHHCCCCCEEEECCCCCCCCHHHHHHHHHH
KGVKRVVLTAPGKGDLKNIVYGINHGDITDADSIVTAASCTTNGITPTLKVINDHYGIEY
CCCEEEEEECCCCCCCCHHEEECCCCCCCCCHHHEEEECCCCCCCCHHHEEEHHCCCCCC
GHVETVHSFTNDQNLIDNFHKGARRGRAAGLNMVLTETGAAKAVSKALPELEGKLTGNAI
CCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEE
RVPTPDVSMAVLNLTLEKEVTREEVNTLMDKVALHSDLRQQISYIQSPEVVSSDFVGTTH
ECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCH
AGIVDGLATIANGKHLVLYVWYDNEFGYSNQVIRIVEHVAGARPTVLPERIASAEL
HHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8508805; 10360571; 2401296; 7877172 [H]