Click here to switch to the map view.

The map label for this gene is insK [C]

Identifier: 38233440

GI number: 38233440

Start: 820987

End: 822363

Strand: Reverse

Name: insK [C]

Synonym: DIP0843

Alternate gene names: 38233440

Gene position: 822363-820987 (Counterclockwise)

Preceding gene: 38233443

Following gene: 38233433

Centisome position: 33.04

GC content: 48.95

Gene sequence:

>1377_bases
ATGAACCGTTCCTACACCAACACGCAGAAGCGCACAGCACTGCGGGTCTACAAACGCACACAATCAGTGACTAAAACAGT
CCGCGAACTCGGCTACCCAGGCAGATGGACCCTGTATAAATGGCTACGCGAGCCCAAAACCCCACCACAACCACGTAAAC
AAGCCAAAACCCTGACCCACTACCCATACGAAGTCAAACTTCGCGCAGTAGAACTTTTCCACAATGGTTGGCGACCAGCT
GATATTGCCCAGGAATGCTGCCTGCACACTCACGCCAGCGTCTATGCTTGGGCGCAACGCTACCGTGAGGAAGGACAATG
GGGCTTGATGTCGAAAAAAGAACGCGCAGGCCATGGCCGCATCCCTACTAAAGCAGCACTAGAAAAATCATTGCCGGATA
ATCCAACACAGTTAAAACAGCAGATGGCCACGCTGCTGGTAGAAAAAGCCGTGTTGGAAAAGGAGCTGGAAATTATAAAA
AAAGACGTAAGCGTCATCCCCGGTCAGCTGAGTAATAAGCACAAAACCGACGTGGTTGACGCTTTGCGTAGCACGTTTCC
ATTAGCAATGCTGCTCGCTGCTAGTGGTCTTGCTGCATCCAGTTTCTATTACCACCTGAAAAAACGACGCATGCCTGATA
AGCACGCAGCTATTCGCAGCATGGTGCACCGCATCAGTTCTGATTCACATAATACCTATGGTTATCGCCGTATCTGGTGG
CAATTACGACATTTAGGCATAACTATCAGTGAAAAAGTAGTTCGCAGGCTCATGCGCGAAGAAGCAATTACGGTGCGGTT
TCCGAAGCGGAAGGTGAAATATTCAGTATCAGGAGAAATTTCTCCGGCTCCGCCGAACCTGGTCAACCGTTGTTTTCATG
CCACTGCTGCGAATACGTTGTGGCTGACTGATATTAGTGTTTTCGCTGTGAATGAGGGGCGGGTGTATTTGTCTGTGATT
ATTGATTGTTTCGATGGCAAAGTCGTTGCTGCTAAGACGAGTGTGAATCCCACTATGGAGTTAGCAGAATCTACGCTGCA
GGCCGCTATTGATGCTGAGGGTCTTCCACCGGATGGTTCATTAGTGATTCATTCAGATCGTGGTGTGCATTACCGTGGTC
GGAGTTGGCATAGTCTGACTGCGAAATATGGCATCGTTCGTTCGATGTCGAAAAAGGGGTGTAGTCCTGACAATGCGGCA
TGCGAGGGGTTTTTCGGGCGGATGAAAAATGAGATGTATTACGGCAAGAGGTGGCAGACAATCCAAGAGCTTGACGATGC
CATTGCTGCTTATATCGAGTTTTATAACAATCATCGCATTAAAGTTAGTCTCAATGGTATGAGTATCGCGCGTTATCGCA
TGGCTGCGGTAGCGTGA

Upstream 100 bases:

>100_bases
AAACATTGCCTGAGGCCCTAACGCCCATTGCGTTTGACCGAAAACACTGAATTCAGGCCGAACAGGCGGGGATGCGGACG
GAATCTTGGAGGATTCCATT

Downstream 100 bases:

>100_bases
GGTTGAAAGTGTCTAACAAAACGTCCGCATCCCCGGCTGATCGTTAACCTGAGTTTGCGGATCACCGCCTTGTGCCAGGA
CAGCCCCAACTTTTTCCCGT

Product: putative transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAKTLTHYPYEVKLRAVELFHNGWRPA
DIAQECCLHTHASVYAWAQRYREEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKELEIIK
KDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHAAIRSMVHRISSDSHNTYGYRRIWW
QLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSVSGEISPAPPNLVNRCFHATAANTLWLTDISVFAVNEGRVYLSVI
IDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCSPDNAA
CEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMAAVA

Sequences:

>Translated_458_residues
MNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAKTLTHYPYEVKLRAVELFHNGWRPA
DIAQECCLHTHASVYAWAQRYREEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKELEIIK
KDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHAAIRSMVHRISSDSHNTYGYRRIWW
QLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSVSGEISPAPPNLVNRCFHATAANTLWLTDISVFAVNEGRVYLSVI
IDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCSPDNAA
CEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMAAVA
>Mature_458_residues
MNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAKTLTHYPYEVKLRAVELFHNGWRPA
DIAQECCLHTHASVYAWAQRYREEGQWGLMSKKERAGHGRIPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKELEIIK
KDVSVIPGQLSNKHKTDVVDALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHAAIRSMVHRISSDSHNTYGYRRIWW
QLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSVSGEISPAPPNLVNRCFHATAANTLWLTDISVFAVNEGRVYLSVI
IDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGSLVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCSPDNAA
CEGFFGRMKNEMYYGKRWQTIQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMAAVA

Specific function: Probably involved in the transposition of insertion sequence IS1353 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=261, Percent_Identity=26.8199233716475, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1789981, Length=276, Percent_Identity=38.4057971014493, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1788405, Length=276, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787263, Length=276, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786753, Length=276, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786570, Length=276, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786490, Length=276, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337
- InterPro:   IPR002514 [H]

Pfam domain/function: PF00665 rve; PF01527 Transposase_8 [H]

EC number: NA

Molecular weight: Translated: 52252; Mature: 52252

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAKTLTH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHC
YPYEVKLRAVELFHNGWRPADIAQECCLHTHASVYAWAQRYREEGQWGLMSKKERAGHGR
CCEEEEHHHEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCC
IPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKELEIIKKDVSVIPGQLSNKHKTDVVD
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHAAIRSMVHRISSDSHNTYGYRRIWW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
QLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSVSGEISPAPPNLVNRCFHATAANTL
HHHHCCCCHHHHHHHHHHHHCCEEEECCCHHEEEEECCCCCCCCHHHHHHHHHHHCCCEE
WLTDISVFAVNEGRVYLSVIIDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGS
EEEEEEEEEEECCCEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCC
LVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCSPDNAACEGFFGRMKNEMYYGKRWQT
EEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHH
IQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMAAVA
HHHHHHHHHHHHHHHCCCEEEEEECCCEEHHHHHHHCC
>Mature Secondary Structure
MNRSYTNTQKRTALRVYKRTQSVTKTVRELGYPGRWTLYKWLREPKTPPQPRKQAKTLTH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHC
YPYEVKLRAVELFHNGWRPADIAQECCLHTHASVYAWAQRYREEGQWGLMSKKERAGHGR
CCEEEEHHHEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCC
IPTKAALEKSLPDNPTQLKQQMATLLVEKAVLEKELEIIKKDVSVIPGQLSNKHKTDVVD
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ALRSTFPLAMLLAASGLAASSFYYHLKKRRMPDKHAAIRSMVHRISSDSHNTYGYRRIWW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
QLRHLGITISEKVVRRLMREEAITVRFPKRKVKYSVSGEISPAPPNLVNRCFHATAANTL
HHHHCCCCHHHHHHHHHHHHCCEEEECCCHHEEEEECCCCCCCCHHHHHHHHHHHCCCEE
WLTDISVFAVNEGRVYLSVIIDCFDGKVVAAKTSVNPTMELAESTLQAAIDAEGLPPDGS
EEEEEEEEEEECCCEEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCC
LVIHSDRGVHYRGRSWHSLTAKYGIVRSMSKKGCSPDNAACEGFFGRMKNEMYYGKRWQT
EEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHH
IQELDDAIAAYIEFYNNHRIKVSLNGMSIARYRMAAVA
HHHHHHHHHHHHHHHCCCEEEEEECCCEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755869; 12499211 [H]