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The map label for this gene is cobF [H]

Identifier: 38233419

GI number: 38233419

Start: 796088

End: 796840

Strand: Direct

Name: cobF [H]

Synonym: DIP0822

Alternate gene names: 38233419

Gene position: 796088-796840 (Clockwise)

Preceding gene: 38233418

Following gene: 38233424

Centisome position: 31.99

GC content: 56.44

Gene sequence:

>753_bases
ATGCGCACCATTTATGTAATTGGAATTGGTACTGGCAGCCCCGAGTTCCTGACTCTTCAGGCGATCTCGGGGCTTCGTCA
TGCACAAGCTATAGTAGCCCTAGATAAGGGCGAGCAGAAGTCCGATCTTCTGGCGCTTCGTCAGAAGATTGTCGATACTC
ATGCGCCAGGTACCCCCATTTATGCAGTTACGGATCCGGAGCGCGACCGCAATCCTGACAACTATGAGGAAGAGGTGCGC
CGGTGGCATGCAGAGCGCGCCCATCTGTTGGCCTCAACGATCCGTGAGCGCACGCCCGACGACGGCGCTGTGGCGTTTTT
AGTGTGGGGTGACCCTTCGCTCTACGATTCCACGCTGCGCATTATCGAGCACATGCGTAACCTCGAGGATCTCCACGCGG
ATGTCAAGGTGATCCCAGGTATTACCGCTGTTCAAGTTCTCACCGCTGAGCACGGTATTTTGATCAACCGTATTGGCGAG
GCCATTCACATTACGACGGGCCGAAACCTCCCCGAAACATCGGCGAAGGATCGTCGCAACTGCGTGGTCATGCTGGACGG
TAAAACTGCGTGGCAAGACGTTGCCACGGAGCACACCTATATGTGGTGGGGTGCGTTTTTGGGCACCGAGCAGCAAGTGC
TGCGCAAGGGGTATGTCCATGAAATCGGCGCGCAGGTTGCCGAATTGAAGCAGCAGCTGCGCACCGAGCACGGGTGGATT
ATGGATACCTACCTGCTGCGAGAGCTCGATTAG

Upstream 100 bases:

>100_bases
TTTGCACCAGCAGAATTCCATTGACTTTGCCAATGTGAATACGTTGCTGACTGATATTGACCGCCATAACCTTCACGTGG
ACGACGAAGACTAAGAATCA

Downstream 100 bases:

>100_bases
GTAGGAATCATTTGAAAACTATCCTGCTAGTTCCTCTAGCTTCTTGCGAACGTCGGAAGCTGGGGGATTAGTAGCGGTGG
TGCCGTCAGAGTACTTCACG

Product: precorrin 6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MRTIYVIGIGTGSPEFLTLQAISGLRHAQAIVALDKGEQKSDLLALRQKIVDTHAPGTPIYAVTDPERDRNPDNYEEEVR
RWHAERAHLLASTIRERTPDDGAVAFLVWGDPSLYDSTLRIIEHMRNLEDLHADVKVIPGITAVQVLTAEHGILINRIGE
AIHITTGRNLPETSAKDRRNCVVMLDGKTAWQDVATEHTYMWWGAFLGTEQQVLRKGYVHEIGAQVAELKQQLRTEHGWI
MDTYLLRELD

Sequences:

>Translated_250_residues
MRTIYVIGIGTGSPEFLTLQAISGLRHAQAIVALDKGEQKSDLLALRQKIVDTHAPGTPIYAVTDPERDRNPDNYEEEVR
RWHAERAHLLASTIRERTPDDGAVAFLVWGDPSLYDSTLRIIEHMRNLEDLHADVKVIPGITAVQVLTAEHGILINRIGE
AIHITTGRNLPETSAKDRRNCVVMLDGKTAWQDVATEHTYMWWGAFLGTEQQVLRKGYVHEIGAQVAELKQQLRTEHGWI
MDTYLLRELD
>Mature_250_residues
MRTIYVIGIGTGSPEFLTLQAISGLRHAQAIVALDKGEQKSDLLALRQKIVDTHAPGTPIYAVTDPERDRNPDNYEEEVR
RWHAERAHLLASTIRERTPDDGAVAFLVWGDPSLYDSTLRIIEHMRNLEDLHADVKVIPGITAVQVLTAEHGILINRIGE
AIHITTGRNLPETSAKDRRNCVVMLDGKTAWQDVATEHTYMWWGAFLGTEQQVLRKGYVHEIGAQVAELKQQLRTEHGWI
MDTYLLRELD

Specific function: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR012797 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.152 [H]

Molecular weight: Translated: 28244; Mature: 28244

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIYVIGIGTGSPEFLTLQAISGLRHAQAIVALDKGEQKSDLLALRQKIVDTHAPGTPI
CEEEEEEEECCCCCCEEEHHHHHCHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCE
YAVTDPERDRNPDNYEEEVRRWHAERAHLLASTIRERTPDDGAVAFLVWGDPSLYDSTLR
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHH
IIEHMRNLEDLHADVKVIPGITAVQVLTAEHGILINRIGEAIHITTGRNLPETSAKDRRN
HHHHHHHHHHHHCCCEECCCCCEEEEEHHCCCCCEECCCCEEEEECCCCCCCCCCCCCCC
CVVMLDGKTAWQDVATEHTYMWWGAFLGTEQQVLRKGYVHEIGAQVAELKQQLRTEHGWI
EEEEECCCHHHHHHHCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MDTYLLRELD
HHHHHHHHCC
>Mature Secondary Structure
MRTIYVIGIGTGSPEFLTLQAISGLRHAQAIVALDKGEQKSDLLALRQKIVDTHAPGTPI
CEEEEEEEECCCCCCEEEHHHHHCHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCCE
YAVTDPERDRNPDNYEEEVRRWHAERAHLLASTIRERTPDDGAVAFLVWGDPSLYDSTLR
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHH
IIEHMRNLEDLHADVKVIPGITAVQVLTAEHGILINRIGEAIHITTGRNLPETSAKDRRN
HHHHHHHHHHHHCCCEECCCCCEEEEEHHCCCCCEECCCCEEEEECCCCCCCCCCCCCCC
CVVMLDGKTAWQDVATEHTYMWWGAFLGTEQQVLRKGYVHEIGAQVAELKQQLRTEHGWI
EEEEECCCHHHHHHHCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MDTYLLRELD
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]