Click here to switch to the map view.

The map label for this gene is yicO [C]

Identifier: 38233379

GI number: 38233379

Start: 759111

End: 760598

Strand: Direct

Name: yicO [C]

Synonym: DIP0780

Alternate gene names: 38233379

Gene position: 759111-760598 (Clockwise)

Preceding gene: 38233378

Following gene: 38233380

Centisome position: 30.5

GC content: 56.05

Gene sequence:

>1488_bases
ATGGCATCGACGGCCCCTCAGTCGCAAACCTCAGCGCCCACGGCTAGCACCTCGCAGCCGCGCAGCGCGCTTGACCGATA
CTTCAAAATCAGCGAACGCGGTTCCTCAGTAGGCACCGAGGTTCGCGCAGGCGTAGTGACCTTCTTCGCGATGGCCTACA
TCATCATCCTTAACCCGTTGATCCTAGGAACGGGCGAGGACATCAACGGCAAAGTGCTGGGGATTCCTCAGGTAGCAGCG
GCAACAGCTTTAGCTGCAGGCGTAGCCACCATTGCCTTTGGTCTGATTGCGCGCTACCCCTTCGGTATCGCAGCAGGACT
GGGTATTAACACCCTCGTGGCCGTTACAATGGTGGCAACCGAAGGATTGTCTTGGGAAGAAGCCATGGGTCTTGTTGTCC
TCGACGGCATCATTATCGTGTTACTCGCGATCTCTGGTTTCCGCGCTGCTGTATTTTCTGCCATCCCGAAGCCCATGATC
GCCGCTATGAGCGTCGGCATTGGTATGTTCATCGCCTTGATCGGTCTTGTCGACGCAGGCTTCGTTCGCCGTATCCCAGA
CGCGGCTCACACCACAGTCCCCGTGGGGCTTGGTACCGGCGGATCCATTTCTTCTTGGCCAACCCTCGTATTCATCATGG
GCTTGCTCATCTGCGGTTTCATGGTGGTTCGCCGCGTCCGCGGTGGTCTTTTCCTCGGCATTGTTGTTACCACCATCATC
GCCATGATCGTTGAAGCCATAACTGGTGCTGGCTCCTCGGTAGATAACCCAACCGGCGGCTGGAGCCTCGCTGTTCCTAC
CACGCCTGGGGGCTTGGGCGGCTTGCCAGATCTCTCTTTGATCGGTGACATCTCCCTCTTCGGCGCATTTACCCGCGTCG
GCGCACTTGGTGCGACACTGTTGCTGTTTACTCTCGTGTTGGCCAACTTCTTCGACGCAATGGGCACCATGACCGCGTTG
GGCAAGCAAGCTGAGCTTGTCGACGATTCCGGCGTGCTGCCAGACATGAAGAAGGCTCTGATCGTTGAGGGCACCGGTGC
GATCATCGGTGGCGCAGCGTCAGCTTCCTCAAATACTGTCTATGTGGATTCCGCAGCAGGCATCGCAGATGGTGCTCGCA
CAGGACTTGCCAACGTGGTCACAGGCGTACTGTTCTTGCTGGCTATGTTCTTAACCCCGCTGTATGAGATCGTGCCTATC
GAGGCTGCCGCACCTGTCCTCGTGGTCGTTGGTGCTCTTATGATCGGCCAGGTCCGAGACATCGACTTCACCGATTTCCA
TATCGCGTTGCCAGCATTCTTGACTATCGTGATTATGCCATTTACCTACTCGATCGCAAACGGTATCGGCGTCGGATTCA
TCTCCTTTACTCTGCTGGCAGTATTCGCCGGCAAGATCAAGCAGATCCACTGGATCATGTGGCTGATTTCAGCACTATTC
GTGGTGTACTTTGCTATGGATCCAATCTTGAACGCTATCGGTTCATAA

Upstream 100 bases:

>100_bases
GGTACTGATTTTCGGTTTGATTGCAGGTCAAATACGTGCCACTATCTACGAATGCGGATGAAATTCCGGTTCCCCCTGTA
CTTGTATGGAGCAAAAGTAG

Downstream 100 bases:

>100_bases
AAAGAAACGCTTTCACCCGAACCCCCTTCTCAGCATGCGGTTGCAAACAGCCACGGAGCGTACTGGGAAGGGGGATTCGT
GTATTTAGCGGGCAGGGTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MASTAPQSQTSAPTASTSQPRSALDRYFKISERGSSVGTEVRAGVVTFFAMAYIIILNPLILGTGEDINGKVLGIPQVAA
ATALAAGVATIAFGLIARYPFGIAAGLGINTLVAVTMVATEGLSWEEAMGLVVLDGIIIVLLAISGFRAAVFSAIPKPMI
AAMSVGIGMFIALIGLVDAGFVRRIPDAAHTTVPVGLGTGGSISSWPTLVFIMGLLICGFMVVRRVRGGLFLGIVVTTII
AMIVEAITGAGSSVDNPTGGWSLAVPTTPGGLGGLPDLSLIGDISLFGAFTRVGALGATLLLFTLVLANFFDAMGTMTAL
GKQAELVDDSGVLPDMKKALIVEGTGAIIGGAASASSNTVYVDSAAGIADGARTGLANVVTGVLFLLAMFLTPLYEIVPI
EAAAPVLVVVGALMIGQVRDIDFTDFHIALPAFLTIVIMPFTYSIANGIGVGFISFTLLAVFAGKIKQIHWIMWLISALF
VVYFAMDPILNAIGS

Sequences:

>Translated_495_residues
MASTAPQSQTSAPTASTSQPRSALDRYFKISERGSSVGTEVRAGVVTFFAMAYIIILNPLILGTGEDINGKVLGIPQVAA
ATALAAGVATIAFGLIARYPFGIAAGLGINTLVAVTMVATEGLSWEEAMGLVVLDGIIIVLLAISGFRAAVFSAIPKPMI
AAMSVGIGMFIALIGLVDAGFVRRIPDAAHTTVPVGLGTGGSISSWPTLVFIMGLLICGFMVVRRVRGGLFLGIVVTTII
AMIVEAITGAGSSVDNPTGGWSLAVPTTPGGLGGLPDLSLIGDISLFGAFTRVGALGATLLLFTLVLANFFDAMGTMTAL
GKQAELVDDSGVLPDMKKALIVEGTGAIIGGAASASSNTVYVDSAAGIADGARTGLANVVTGVLFLLAMFLTPLYEIVPI
EAAAPVLVVVGALMIGQVRDIDFTDFHIALPAFLTIVIMPFTYSIANGIGVGFISFTLLAVFAGKIKQIHWIMWLISALF
VVYFAMDPILNAIGS
>Mature_494_residues
ASTAPQSQTSAPTASTSQPRSALDRYFKISERGSSVGTEVRAGVVTFFAMAYIIILNPLILGTGEDINGKVLGIPQVAAA
TALAAGVATIAFGLIARYPFGIAAGLGINTLVAVTMVATEGLSWEEAMGLVVLDGIIIVLLAISGFRAAVFSAIPKPMIA
AMSVGIGMFIALIGLVDAGFVRRIPDAAHTTVPVGLGTGGSISSWPTLVFIMGLLICGFMVVRRVRGGLFLGIVVTTIIA
MIVEAITGAGSSVDNPTGGWSLAVPTTPGGLGGLPDLSLIGDISLFGAFTRVGALGATLLLFTLVLANFFDAMGTMTALG
KQAELVDDSGVLPDMKKALIVEGTGAIIGGAASASSNTVYVDSAAGIADGARTGLANVVTGVLFLLAMFLTPLYEIVPIE
AAAPVLVVVGALMIGQVRDIDFTDFHIALPAFLTIVIMPFTYSIANGIGVGFISFTLLAVFAGKIKQIHWIMWLISALFV
VYFAMDPILNAIGS

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=468, Percent_Identity=34.6153846153846, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI1790150, Length=474, Percent_Identity=32.7004219409283, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1790499, Length=479, Percent_Identity=32.776617954071, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI48994909, Length=476, Percent_Identity=32.3529411764706, Blast_Score=196, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 50789; Mature: 50658

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTAPQSQTSAPTASTSQPRSALDRYFKISERGSSVGTEVRAGVVTFFAMAYIIILNPL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ILGTGEDINGKVLGIPQVAAATALAAGVATIAFGLIARYPFGIAAGLGINTLVAVTMVAT
HCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHH
EGLSWEEAMGLVVLDGIIIVLLAISGFRAAVFSAIPKPMIAAMSVGIGMFIALIGLVDAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
FVRRIPDAAHTTVPVGLGTGGSISSWPTLVFIMGLLICGFMVVRRVRGGLFLGIVVTTII
HHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AMIVEAITGAGSSVDNPTGGWSLAVPTTPGGLGGLPDLSLIGDISLFGAFTRVGALGATL
HHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLFTLVLANFFDAMGTMTALGKQAELVDDSGVLPDMKKALIVEGTGAIIGGAASASSNTV
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHEEEECCCCEEECCCCCCCCEE
YVDSAAGIADGARTGLANVVTGVLFLLAMFLTPLYEIVPIEAAAPVLVVVGALMIGQVRD
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
IDFTDFHIALPAFLTIVIMPFTYSIANGIGVGFISFTLLAVFAGKIKQIHWIMWLISALF
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVYFAMDPILNAIGS
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASTAPQSQTSAPTASTSQPRSALDRYFKISERGSSVGTEVRAGVVTFFAMAYIIILNPL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ILGTGEDINGKVLGIPQVAAATALAAGVATIAFGLIARYPFGIAAGLGINTLVAVTMVAT
HCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHH
EGLSWEEAMGLVVLDGIIIVLLAISGFRAAVFSAIPKPMIAAMSVGIGMFIALIGLVDAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
FVRRIPDAAHTTVPVGLGTGGSISSWPTLVFIMGLLICGFMVVRRVRGGLFLGIVVTTII
HHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AMIVEAITGAGSSVDNPTGGWSLAVPTTPGGLGGLPDLSLIGDISLFGAFTRVGALGATL
HHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLFTLVLANFFDAMGTMTALGKQAELVDDSGVLPDMKKALIVEGTGAIIGGAASASSNTV
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHEEEECCCCEEECCCCCCCCEE
YVDSAAGIADGARTGLANVVTGVLFLLAMFLTPLYEIVPIEAAAPVLVVVGALMIGQVRD
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
IDFTDFHIALPAFLTIVIMPFTYSIANGIGVGFISFTLLAVFAGKIKQIHWIMWLISALF
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVYFAMDPILNAIGS
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]