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The map label for this gene is mpg1 [H]

Identifier: 38233289

GI number: 38233289

Start: 658206

End: 659294

Strand: Direct

Name: mpg1 [H]

Synonym: DIP0682

Alternate gene names: 38233289

Gene position: 658206-659294 (Clockwise)

Preceding gene: 38233288

Following gene: 38233290

Centisome position: 26.45

GC content: 54.36

Gene sequence:

>1089_bases
ATGACTGAAACAACACTGCGCAGCGACACAGATGCTGTGATCCTTGTTGGAGGTAAGGGCACTAGGTTGCGTCCGCTGAC
TGTGTCGACTCCAAAGCCCATGCTGCCTACGGCAGGTGTGCCGTTCCTTTCGCATTTGCTTGCGCGTATCAAGGCTGCCG
GTATCACGCATGTGGTGCTGGGTACGTCGTTTAAGGCGGAGGTGTTTGAGGACTACTTCGGTGATGGTGCTGATCTCGGC
TTGGAGATTGAGTACGTGGTGGAGGATAAGCCATTGGGTACCGGTGGCGGCATTCGGAACGTGTATGACAAGCTTCGTGC
TAACACCGTGATGGTGTTTAACGGCGATGTTCTTGGCGGCACTGATCTTGGTGGAATCCTTGATGCTCACCATGCCAAAA
ACGCTGATTTGACCATGCATTTGGTACGAGTTCCAGATCCTCGTGCGTTTGGTTGTGTGCCCACTGATGCTGAGGGACGA
GTTTCTGCTTTCTTGGAAAAGACCGAGGATCCACCAACGGACCAGATTAATGCTGGTTGCTATGTGTTCCGTCGTGAGCT
GATCGGTGAGATCCCTGCAGATCGAGTGGTGTCTGTGGAGCGCGAGACTTTCCCACGCTTGCTGGAGGAGGGACGCCGCG
TGTTCGGTTATGTAGACAATGCATATTGGCGCGACATGGGTACTCCTTCTGACTTCGTGCGTGGTTCGTCAGATTTGGTT
CGTGGTATTGCGCCGTCGCCGTTGTTGGAAGGTAAGACGGGGGAGTGCCTTGTCGACGAATCCGCTGGTGTTAGCGATGG
TGCGTTGCTTTTGGGCGGTACCGTGATTGGTCGCGGCACTGAAATCGGTGCGGGCTGTCGTTTGGACGACACCGTGGTGT
TTGATGGTGTGACCATTGAGCCGGGTGCTGTGATTGAAGATTCGATTATTGGGCATGGTGCTCGTATTGGAGCCAATGCT
CGCATTACCGGCTGTGTGATTGGTGAAGGCGCGGAAATCGGTGCACGTTGTGAGCTTCGCGACGGCATGCGTGTGTGGCC
AGGAGTTGTGATTCCAACTGCTGGTATCCGTTTTAGTTCGGATGCCTAA

Upstream 100 bases:

>100_bases
AGGACCCTCGGCTACGGCATAACGTTGGTGCAAAGCAATTGTTGTGTTTATGCGATGGGGATAATCCCTCTACACCGATA
AGTAAAGGCACTCGAAACTA

Downstream 100 bases:

>100_bases
GTTGCAGTAATACCTAGTGCAACCTAGTCATAGGCTCCCACCACGGCAGGGTAGACCCCCTCGTTGTGGTGGGAGCTTTC
GCATTTTATGGAGGCTGGCT

Product: putative mannose-1-phosphate guanyltransferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTETTLRSDTDAVILVGGKGTRLRPLTVSTPKPMLPTAGVPFLSHLLARIKAAGITHVVLGTSFKAEVFEDYFGDGADLG
LEIEYVVEDKPLGTGGGIRNVYDKLRANTVMVFNGDVLGGTDLGGILDAHHAKNADLTMHLVRVPDPRAFGCVPTDAEGR
VSAFLEKTEDPPTDQINAGCYVFRRELIGEIPADRVVSVERETFPRLLEEGRRVFGYVDNAYWRDMGTPSDFVRGSSDLV
RGIAPSPLLEGKTGECLVDESAGVSDGALLLGGTVIGRGTEIGAGCRLDDTVVFDGVTIEPGAVIEDSIIGHGARIGANA
RITGCVIGEGAEIGARCELRDGMRVWPGVVIPTAGIRFSSDA

Sequences:

>Translated_362_residues
MTETTLRSDTDAVILVGGKGTRLRPLTVSTPKPMLPTAGVPFLSHLLARIKAAGITHVVLGTSFKAEVFEDYFGDGADLG
LEIEYVVEDKPLGTGGGIRNVYDKLRANTVMVFNGDVLGGTDLGGILDAHHAKNADLTMHLVRVPDPRAFGCVPTDAEGR
VSAFLEKTEDPPTDQINAGCYVFRRELIGEIPADRVVSVERETFPRLLEEGRRVFGYVDNAYWRDMGTPSDFVRGSSDLV
RGIAPSPLLEGKTGECLVDESAGVSDGALLLGGTVIGRGTEIGAGCRLDDTVVFDGVTIEPGAVIEDSIIGHGARIGANA
RITGCVIGEGAEIGARCELRDGMRVWPGVVIPTAGIRFSSDA
>Mature_361_residues
TETTLRSDTDAVILVGGKGTRLRPLTVSTPKPMLPTAGVPFLSHLLARIKAAGITHVVLGTSFKAEVFEDYFGDGADLGL
EIEYVVEDKPLGTGGGIRNVYDKLRANTVMVFNGDVLGGTDLGGILDAHHAKNADLTMHLVRVPDPRAFGCVPTDAEGRV
SAFLEKTEDPPTDQINAGCYVFRRELIGEIPADRVVSVERETFPRLLEEGRRVFGYVDNAYWRDMGTPSDFVRGSSDLVR
GIAPSPLLEGKTGECLVDESAGVSDGALLLGGTVIGRGTEIGAGCRLDDTVVFDGVTIEPGAVIEDSIIGHGARIGANAR
ITGCVIGEGAEIGARCELRDGMRVWPGVVIPTAGIRFSSDA

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761619, Length=348, Percent_Identity=31.0344827586207, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI11761621, Length=340, Percent_Identity=30.8823529411765, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI31881779, Length=354, Percent_Identity=26.5536723163842, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI45447090, Length=354, Percent_Identity=26.5536723163842, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1788351, Length=236, Percent_Identity=25.8474576271186, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789837, Length=413, Percent_Identity=23.728813559322, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790224, Length=236, Percent_Identity=24.5762711864407, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=354, Percent_Identity=30.225988700565, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17509979, Length=332, Percent_Identity=28.6144578313253, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17509981, Length=323, Percent_Identity=27.2445820433437, Blast_Score=117, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6320148, Length=354, Percent_Identity=30.7909604519774, Blast_Score=166, Evalue=5e-42,
Organism=Drosophila melanogaster, GI21355443, Length=358, Percent_Identity=29.608938547486, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24644084, Length=358, Percent_Identity=29.608938547486, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24653912, Length=370, Percent_Identity=27.2972972972973, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 38334; Mature: 38203

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETTLRSDTDAVILVGGKGTRLRPLTVSTPKPMLPTAGVPFLSHLLARIKAAGITHVVL
CCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEE
GTSFKAEVFEDYFGDGADLGLEIEYVVEDKPLGTGGGIRNVYDKLRANTVMVFNGDVLGG
CCCCHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCEECC
TDLGGILDAHHAKNADLTMHLVRVPDPRAFGCVPTDAEGRVSAFLEKTEDPPTDQINAGC
CCCCCHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCH
YVFRRELIGEIPADRVVSVERETFPRLLEEGRRVFGYVDNAYWRDMGTPSDFVRGSSDLV
HHHHHHHHHCCCCCCEEEECHHHHHHHHHCCCEEEEEECCHHHHCCCCCHHHHCCCHHHH
RGIAPSPLLEGKTGECLVDESAGVSDGALLLGGTVIGRGTEIGAGCRLDDTVVFDGVTIE
HCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCEEEECCCCCCCCCCCCCEEEECCEEEC
PGAVIEDSIIGHGARIGANARITGCVIGEGAEIGARCELRDGMRVWPGVVIPTAGIRFSS
CCCEECHHHHCCCEEECCCCEEEEEEEECCCCCCCEEEECCCCCCCCCEEEECCCEEECC
DA
CC
>Mature Secondary Structure 
TETTLRSDTDAVILVGGKGTRLRPLTVSTPKPMLPTAGVPFLSHLLARIKAAGITHVVL
CCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEE
GTSFKAEVFEDYFGDGADLGLEIEYVVEDKPLGTGGGIRNVYDKLRANTVMVFNGDVLGG
CCCCHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEEECCEECC
TDLGGILDAHHAKNADLTMHLVRVPDPRAFGCVPTDAEGRVSAFLEKTEDPPTDQINAGC
CCCCCHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCH
YVFRRELIGEIPADRVVSVERETFPRLLEEGRRVFGYVDNAYWRDMGTPSDFVRGSSDLV
HHHHHHHHHCCCCCCEEEECHHHHHHHHHCCCEEEEEECCHHHHCCCCCHHHHCCCHHHH
RGIAPSPLLEGKTGECLVDESAGVSDGALLLGGTVIGRGTEIGAGCRLDDTVVFDGVTIE
HCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCEEEECCCCCCCCCCCCCEEEECCEEEC
PGAVIEDSIIGHGARIGANARITGCVIGEGAEIGARCELRDGMRVWPGVVIPTAGIRFSS
CCCEECHHHHCCCEEECCCCEEEEEEEECCCCCCCEEEECCCCCCCCCEEEECCCEEECC
DA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]