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The map label for this gene is hypE [H]

Identifier: 38233275

GI number: 38233275

Start: 643639

End: 644709

Strand: Direct

Name: hypE [H]

Synonym: DIP0668

Alternate gene names: 38233275

Gene position: 643639-644709 (Clockwise)

Preceding gene: 38233272

Following gene: 38233277

Centisome position: 25.86

GC content: 58.73

Gene sequence:

>1071_bases
ATGGAACCCAAGAATCGACTAAACGACGACGAACACAAGGTAAATATCAACATCGATCGCGTACGCGCCCGACCTTTTCG
ATTCACAGACGACAAAGTCACGCTTCAGCACGGAGCAGGCGGAAAAGCCTCGGCCGCTTTGGTAGAAAACATATTCTACT
CCGGATACGGTAACGATCACCTCGAGATGCGTGGCGACGCCGCCGTGGTACCCACAGATGTGGCTGGCGGAACCCTTGCG
TTTTCCACTGACTCCTATGTGGTCAACCCCATCGAATTCCCAGGTGGCAGTATCGGTGATCTTGCGGTTAACGGAACAGT
CAACGACCTCGCGGTATCCGGCGCGATCCCCACGATGATCTCTGCTGCCTTCATCCTCGAAGAAGGCCTCGAGATCGCCA
CGCTCAAGCGCATCGTTGCAGACATGCATGCAGCTGCTGAAACTGCTGGTGTACACATCGTGACCGGTGATACCAAAGTG
GTTCCCAAAGGCACATGCGACAAGCTCTACATCACTACCGCAGGTGTGGGAATCATTCCTGAGGGCCGCACCAGTGCTGA
CCCCCAAATAGGGGATGCGATCATCGTTTCTGGCCCCATCGCCGACCACGGCATGGCCGTCATGATGGCACGTGGTGATC
TCGCCATCAGCGCTCCTATTGAATCCGACACCCGAAGCGTGAACGGCCAAATCGAAGCGCTCTATGCTGCTGGCGTTACC
CCACGCTGGATGCGCGACGCTACCCGTGGCGGACTTGCTACCGTCATGAACGAGCTCGCCCGAGCCACCGGCCTAGGCGT
AGCCCTCAACGACCCGCTGCCAGTTCGCGATATGACCCGAGCCGCCTGCGACATGCTCGGCATCGACCCCATGTACGTAG
CAAACGAAGGCACCTTCGTGGCGATCGTTCCCGCCGACCAAGTAGACACCGCACTGGCAACCATCCCCGAAGCCAGCTGC
ATCGGCCAGATCGTGGAACAACCAGCCGCATCCGTCGTCCTGCGTACCGGCTTCGGCGGCTCCCGCATGGTGGACATGTT
GGTCGGCGACCCGCTACCACGAATCTGCTAA

Upstream 100 bases:

>100_bases
AGTCATGAATTTCCGCAATTTGGGCGGGCACCCCAAGGCACATAGATTTACTCCTCATATCCTTCAATACCGCTAGAAAA
CACTACCAAGGAAACAATCG

Downstream 100 bases:

>100_bases
TGACTAAGCTAGGCGGTGCTCACAGTCCAACGTCCCAGCACCGCCTGGCCGAGGCTTAACCCGCCATCATTCGGCGGCAC
AATTTGATGGCGCATATCAA

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MEPKNRLNDDEHKVNINIDRVRARPFRFTDDKVTLQHGAGGKASAALVENIFYSGYGNDHLEMRGDAAVVPTDVAGGTLA
FSTDSYVVNPIEFPGGSIGDLAVNGTVNDLAVSGAIPTMISAAFILEEGLEIATLKRIVADMHAAAETAGVHIVTGDTKV
VPKGTCDKLYITTAGVGIIPEGRTSADPQIGDAIIVSGPIADHGMAVMMARGDLAISAPIESDTRSVNGQIEALYAAGVT
PRWMRDATRGGLATVMNELARATGLGVALNDPLPVRDMTRAACDMLGIDPMYVANEGTFVAIVPADQVDTALATIPEASC
IGQIVEQPAASVVLRTGFGGSRMVDMLVGDPLPRIC

Sequences:

>Translated_356_residues
MEPKNRLNDDEHKVNINIDRVRARPFRFTDDKVTLQHGAGGKASAALVENIFYSGYGNDHLEMRGDAAVVPTDVAGGTLA
FSTDSYVVNPIEFPGGSIGDLAVNGTVNDLAVSGAIPTMISAAFILEEGLEIATLKRIVADMHAAAETAGVHIVTGDTKV
VPKGTCDKLYITTAGVGIIPEGRTSADPQIGDAIIVSGPIADHGMAVMMARGDLAISAPIESDTRSVNGQIEALYAAGVT
PRWMRDATRGGLATVMNELARATGLGVALNDPLPVRDMTRAACDMLGIDPMYVANEGTFVAIVPADQVDTALATIPEASC
IGQIVEQPAASVVLRTGFGGSRMVDMLVGDPLPRIC
>Mature_356_residues
MEPKNRLNDDEHKVNINIDRVRARPFRFTDDKVTLQHGAGGKASAALVENIFYSGYGNDHLEMRGDAAVVPTDVAGGTLA
FSTDSYVVNPIEFPGGSIGDLAVNGTVNDLAVSGAIPTMISAAFILEEGLEIATLKRIVADMHAAAETAGVHIVTGDTKV
VPKGTCDKLYITTAGVGIIPEGRTSADPQIGDAIIVSGPIADHGMAVMMARGDLAISAPIESDTRSVNGQIEALYAAGVT
PRWMRDATRGGLATVMNELARATGLGVALNDPLPVRDMTRAACDMLGIDPMYVANEGTFVAIVPADQVDTALATIPEASC
IGQIVEQPAASVVLRTGFGGSRMVDMLVGDPLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=341, Percent_Identity=42.8152492668622, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 37152; Mature: 37152

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPKNRLNDDEHKVNINIDRVRARPFRFTDDKVTLQHGAGGKASAALVENIFYSGYGNDH
CCCCCCCCCCCEEEEEEEEEEECCCEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCE
LEMRGDAAVVPTDVAGGTLAFSTDSYVVNPIEFPGGSIGDLAVNGTVNDLAVSGAIPTMI
EEECCCEEEEECCCCCCEEEEECCCEEEEEEECCCCCCCCEEECCCHHHEEECCCHHHHH
SAAFILEEGLEIATLKRIVADMHAAAETAGVHIVTGDTKVVPKGTCDKLYITTAGVGIIP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCCCCCEEEEEECCEEECC
EGRTSADPQIGDAIIVSGPIADHGMAVMMARGDLAISAPIESDTRSVNGQIEALYAAGVT
CCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCEEEECCCCCCCCCCCCEEEEEEECCCC
PRWMRDATRGGLATVMNELARATGLGVALNDPLPVRDMTRAACDMLGIDPMYVANEGTFV
HHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCEE
AIVPADQVDTALATIPEASCIGQIVEQPAASVVLRTGFGGSRMVDMLVGDPLPRIC
EEEECCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEPKNRLNDDEHKVNINIDRVRARPFRFTDDKVTLQHGAGGKASAALVENIFYSGYGNDH
CCCCCCCCCCCEEEEEEEEEEECCCEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCE
LEMRGDAAVVPTDVAGGTLAFSTDSYVVNPIEFPGGSIGDLAVNGTVNDLAVSGAIPTMI
EEECCCEEEEECCCCCCEEEEECCCEEEEEEECCCCCCCCEEECCCHHHEEECCCHHHHH
SAAFILEEGLEIATLKRIVADMHAAAETAGVHIVTGDTKVVPKGTCDKLYITTAGVGIIP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCCCCCEEEEEECCEEECC
EGRTSADPQIGDAIIVSGPIADHGMAVMMARGDLAISAPIESDTRSVNGQIEALYAAGVT
CCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCEEEECCCCCCCCCCCCEEEEEEECCCC
PRWMRDATRGGLATVMNELARATGLGVALNDPLPVRDMTRAACDMLGIDPMYVANEGTFV
HHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCEE
AIVPADQVDTALATIPEASCIGQIVEQPAASVVLRTGFGGSRMVDMLVGDPLPRIC
EEEECCHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]