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The map label for this gene is rbsK [H]

Identifier: 38233262

GI number: 38233262

Start: 630494

End: 631399

Strand: Reverse

Name: rbsK [H]

Synonym: DIP0655

Alternate gene names: 38233262

Gene position: 631399-630494 (Counterclockwise)

Preceding gene: 38233263

Following gene: 38233261

Centisome position: 25.37

GC content: 58.17

Gene sequence:

>906_bases
ATGTCCTCATCTATGACTGTTGTTGGTTCGATCAACGCTGACGTCAGCATCCAAGTAGCACGACATCCCAGCCCAGGTGA
AACCGTCCTAGGCCACGACTCCACCATCAGCCCCGGCGGCAAAGGCGCAAACCAAGCCGTTGCCGCTGCGCTCCAAGGCG
CATCAGTATCTTTCGTAGGCGCAGTAGGAAACGACACCTATGCCGACCACGCACTAAAAATCCTGCGATCTTCCGGCGTG
AACTTAGACGCAGTCGAAACAATCGACGACAACACCGGCGTTGCGTACATTCAAGTCTCCGACGATGGCGAAAACAGCAT
CATCGTTATTCCCGGCGCGAACGCGCATGTCACCGCGGACTACGTAGAGCACCATCGTAAACCCATTGAGGACGCCGACA
TCGTGCTCTTACAGGGTGAGATTCCCGCGGATGGTTTTAGCGCCGCAGTGCAGGCAGCTCGAGGCACCGTGGTAGTCAAT
CTTGCGCCTGTGATTGATGTCGATCGTGACTGTCTCCTACGCGCGGATCCGTTGATGGCTAATGAGCATGAGGCGGCGTT
GATTCTAGAGCAACTCGGCGTTCCGGTAACCAGTGAAGATCCCCGCGTTCTGATCGAGGCACTGCGTTCGCAAGGGTTTG
CCTCCGTGGTGTTGACCCTTGGTGGACATGGCGCGCTGGTCGCCGATGCTTCTGGTGTGACGCCGATTGCCACCCCATAC
GTCACAGCAGTAGACACCACGGGTGCTGGTGACGCATTCGCGGGGGCTTTCGTGGCACGTCGTTTGCAAGGAGACTCGCT
TATCGACGCCGCCACGTTCGCAGCCCGTGTCGGAGCGTTCTCCGTTCAAGGTCGCGGGGCGCAAACTTCTTATCCTTCTG
AGTCCGATACGCTGCCCGCGGTGTAG

Upstream 100 bases:

>100_bases
TTCCTTAATAATGGTGAATAAGTACTTCCCAAGGACTACCTACGCCCTTGACGTAGACGGTGGCTACCATGCTGCTGTGG
AAAGGAGAGACTGAAAAAGT

Downstream 100 bases:

>100_bases
CGCCTACTATAGGTGAGCATGAATATCGTGCTCGCCTCGTCTTCTCCATCTCGGTTATCAATTCTGCGCAGCGCTGGTGT
CGAACCACTCGTGTGCCCCG

Product: putative ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSSSMTVVGSINADVSIQVARHPSPGETVLGHDSTISPGGKGANQAVAAALQGASVSFVGAVGNDTYADHALKILRSSGV
NLDAVETIDDNTGVAYIQVSDDGENSIIVIPGANAHVTADYVEHHRKPIEDADIVLLQGEIPADGFSAAVQAARGTVVVN
LAPVIDVDRDCLLRADPLMANEHEAALILEQLGVPVTSEDPRVLIEALRSQGFASVVLTLGGHGALVADASGVTPIATPY
VTAVDTTGAGDAFAGAFVARRLQGDSLIDAATFAARVGAFSVQGRGAQTSYPSESDTLPAV

Sequences:

>Translated_301_residues
MSSSMTVVGSINADVSIQVARHPSPGETVLGHDSTISPGGKGANQAVAAALQGASVSFVGAVGNDTYADHALKILRSSGV
NLDAVETIDDNTGVAYIQVSDDGENSIIVIPGANAHVTADYVEHHRKPIEDADIVLLQGEIPADGFSAAVQAARGTVVVN
LAPVIDVDRDCLLRADPLMANEHEAALILEQLGVPVTSEDPRVLIEALRSQGFASVVLTLGGHGALVADASGVTPIATPY
VTAVDTTGAGDAFAGAFVARRLQGDSLIDAATFAARVGAFSVQGRGAQTSYPSESDTLPAV
>Mature_300_residues
SSSMTVVGSINADVSIQVARHPSPGETVLGHDSTISPGGKGANQAVAAALQGASVSFVGAVGNDTYADHALKILRSSGVN
LDAVETIDDNTGVAYIQVSDDGENSIIVIPGANAHVTADYVEHHRKPIEDADIVLLQGEIPADGFSAAVQAARGTVVVNL
APVIDVDRDCLLRADPLMANEHEAALILEQLGVPVTSEDPRVLIEALRSQGFASVVLTLGGHGALVADASGVTPIATPYV
TAVDTTGAGDAFAGAFVARRLQGDSLIDAATFAARVGAFSVQGRGAQTSYPSESDTLPAV

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=305, Percent_Identity=35.7377049180328, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=35.4515050167224, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788491, Length=283, Percent_Identity=26.8551236749117, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788484, Length=289, Percent_Identity=26.2975778546713, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=299, Percent_Identity=36.7892976588629, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319884, Length=327, Percent_Identity=31.1926605504587, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=38.0794701986755, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24583886, Length=298, Percent_Identity=31.8791946308725, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30640; Mature: 30509

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSMTVVGSINADVSIQVARHPSPGETVLGHDSTISPGGKGANQAVAAALQGASVSFVG
CCCCEEEEEECCCCEEEEEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEE
AVGNDTYADHALKILRSSGVNLDAVETIDDNTGVAYIQVSDDGENSIIVIPGANAHVTAD
ECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCEEEHH
YVEHHRKPIEDADIVLLQGEIPADGFSAAVQAARGTVVVNLAPVIDVDRDCLLRADPLMA
HHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEEECEEECCCHHEEECCCCCC
NEHEAALILEQLGVPVTSEDPRVLIEALRSQGFASVVLTLGGHGALVADASGVTPIATPY
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCCCCE
VTAVDTTGAGDAFAGAFVARRLQGDSLIDAATFAARVGAFSVQGRGAQTSYPSESDTLPA
EEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCC
V
C
>Mature Secondary Structure 
SSSMTVVGSINADVSIQVARHPSPGETVLGHDSTISPGGKGANQAVAAALQGASVSFVG
CCCEEEEEECCCCEEEEEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEE
AVGNDTYADHALKILRSSGVNLDAVETIDDNTGVAYIQVSDDGENSIIVIPGANAHVTAD
ECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCEEEHH
YVEHHRKPIEDADIVLLQGEIPADGFSAAVQAARGTVVVNLAPVIDVDRDCLLRADPLMA
HHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEEECEEECCCHHEEECCCCCC
NEHEAALILEQLGVPVTSEDPRVLIEALRSQGFASVVLTLGGHGALVADASGVTPIATPY
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCCCCE
VTAVDTTGAGDAFAGAFVARRLQGDSLIDAATFAARVGAFSVQGRGAQTSYPSESDTLPA
EEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]