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The map label for this gene is glmM

Identifier: 38233172

GI number: 38233172

Start: 532453

End: 533796

Strand: Direct

Name: glmM

Synonym: DIP0563

Alternate gene names: 38233172

Gene position: 532453-533796 (Clockwise)

Preceding gene: 38233171

Following gene: 38233173

Centisome position: 21.4

GC content: 55.8

Gene sequence:

>1344_bases
ATGACTCGACTTTTTGGTACTGATGGTGTTCGTGGTTTGGCCAACCGGAAATTGACGGCGTTGCTCGCACTGAAGCTAGG
CGCGGCAGCAGCGGAAGTGTTGACCAAAGATAACAGGAGCACGAGTCGTCGTCCGGTGGCAGTAGTGGGCCGTGACCCCC
GCGTATCCGGCGAAATGCTGGCCGCCGCGCTGTCTGCAGGCATGGCCAGCCGTGGCGTGGACGTTTTGCGTGTTGGCGTG
CTGCCCACGCCTGCAGTGGCTTATCTGACGGACTTCTACGGTGCTGATATGGGTGTGGTGATTTCTGCGAGCCACAACCC
TATGCCAGATAACGGAATCAAGTTCTTTTCTAAAGGCGGTCACAAGTTACCCGATTCGGTCGAGGACGAGATCGAAAAGG
TTATGGAAACCATCCCAGATGGCGGTCCGACCGGACACGGTATTGGTCGTGTGATTGAAGAGGCTGTCGATGCCCAAGAA
ACGTACCTCAAGCATCTCAAAGGTGCGGTACCGCGCAGCCTCGAGGGCATTACAGTAGTGGTGGACTGCGCTAATGGTGC
AGCTAGTGAGGTTGCCCCACTAGCTTATGCTGCCGCGGGCGCCAAGGTTATTCCAATCCACAATCACCCCAATGCGTACA
ACATCAACGATTCTTGCGGCTCAACGCATATCGACCAGGTACAAGCCGCCGTGCTCGAGCACGGTGCTGATCTGGGACTT
GCTCATGATGGCGACGCGGATCGCTGCCTGGCGGTAGATGCTGAAGGCAACGTGGTTGATGGCGACCAAATCATGGCGAT
CCTAGCTCTTGCTATGAAAGAAAACGGTGAGCTGCACAAGTCTACGCTGGTAGCTACTGTGATGAGCAACCTTGGGCTGC
GGTTGGCTATGAAAGAAGCCGGTATTGAATTGCGCACTACAAAAGTGGGTGACCGCTATGTTCTTGAAGAACTCAACGCT
GGTGGCTTTAGCCTCGGTGGTGAGCAATCCGGCCACATCGTGCTGCCAGACCACGGTACGACCGGTGATGGCACATTGAC
AGGGCTGTCCCTCATGTCGCGTATGGCAGAAACTGGTTTGTCGTTGAAGGTATTGGCCTCTGCGATGACTGTGCTGCCAC
AGGTGCTGATCAACGTTCCAGTTTCAGATAAGACCATTATCCAAACGCACCCTGATGTCGTTGCAGCGATGGAACGCGCT
AGTGACGAGCTGGGCGAGGATGGTCGCGTACTGCTGCGCCCATCCGGTACAGAAGAACTGTTCCGCGTGATGGTTGAGGC
CCCAAGTAAGGAGACGGCTCGTCGGATAGCCGCAGATCTGGCTTCGGTGGTGGCCAAGATTTAA

Upstream 100 bases:

>100_bases
ACGTGCAGGAGATGTTCTAAGGCAGTGCTGGGAAGCGTCGATAAGCATGCCTGCGCGGGGAGTATAAGGTTTAGAGCTTC
GGACATGCATAATGGAGGGC

Downstream 100 bases:

>100_bases
TACCTCCCCCTAATAGGGGAGTAGGGAACCGTAGGCCTCCTTGATTACGTCCAAACATTGTGAAGGCACAACGTGATGTG
ACCGTATAACAAGGGGGTTT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTRLFGTDGVRGLANRKLTALLALKLGAAAAEVLTKDNRSTSRRPVAVVGRDPRVSGEMLAAALSAGMASRGVDVLRVGV
LPTPAVAYLTDFYGADMGVVISASHNPMPDNGIKFFSKGGHKLPDSVEDEIEKVMETIPDGGPTGHGIGRVIEEAVDAQE
TYLKHLKGAVPRSLEGITVVVDCANGAASEVAPLAYAAAGAKVIPIHNHPNAYNINDSCGSTHIDQVQAAVLEHGADLGL
AHDGDADRCLAVDAEGNVVDGDQIMAILALAMKENGELHKSTLVATVMSNLGLRLAMKEAGIELRTTKVGDRYVLEELNA
GGFSLGGEQSGHIVLPDHGTTGDGTLTGLSLMSRMAETGLSLKVLASAMTVLPQVLINVPVSDKTIIQTHPDVVAAMERA
SDELGEDGRVLLRPSGTEELFRVMVEAPSKETARRIAADLASVVAKI

Sequences:

>Translated_447_residues
MTRLFGTDGVRGLANRKLTALLALKLGAAAAEVLTKDNRSTSRRPVAVVGRDPRVSGEMLAAALSAGMASRGVDVLRVGV
LPTPAVAYLTDFYGADMGVVISASHNPMPDNGIKFFSKGGHKLPDSVEDEIEKVMETIPDGGPTGHGIGRVIEEAVDAQE
TYLKHLKGAVPRSLEGITVVVDCANGAASEVAPLAYAAAGAKVIPIHNHPNAYNINDSCGSTHIDQVQAAVLEHGADLGL
AHDGDADRCLAVDAEGNVVDGDQIMAILALAMKENGELHKSTLVATVMSNLGLRLAMKEAGIELRTTKVGDRYVLEELNA
GGFSLGGEQSGHIVLPDHGTTGDGTLTGLSLMSRMAETGLSLKVLASAMTVLPQVLINVPVSDKTIIQTHPDVVAAMERA
SDELGEDGRVLLRPSGTEELFRVMVEAPSKETARRIAADLASVVAKI
>Mature_446_residues
TRLFGTDGVRGLANRKLTALLALKLGAAAAEVLTKDNRSTSRRPVAVVGRDPRVSGEMLAAALSAGMASRGVDVLRVGVL
PTPAVAYLTDFYGADMGVVISASHNPMPDNGIKFFSKGGHKLPDSVEDEIEKVMETIPDGGPTGHGIGRVIEEAVDAQET
YLKHLKGAVPRSLEGITVVVDCANGAASEVAPLAYAAAGAKVIPIHNHPNAYNINDSCGSTHIDQVQAAVLEHGADLGLA
HDGDADRCLAVDAEGNVVDGDQIMAILALAMKENGELHKSTLVATVMSNLGLRLAMKEAGIELRTTKVGDRYVLEELNAG
GFSLGGEQSGHIVLPDHGTTGDGTLTGLSLMSRMAETGLSLKVLASAMTVLPQVLINVPVSDKTIIQTHPDVVAAMERAS
DELGEDGRVLLRPSGTEELFRVMVEAPSKETARRIAADLASVVAKI

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=459, Percent_Identity=45.9694989106754, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1788361, Length=447, Percent_Identity=26.6219239373602, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_CORDI (Q6NJ50)

Other databases:

- EMBL:   BX248355
- RefSeq:   NP_938939.1
- ProteinModelPortal:   Q6NJ50
- SMR:   Q6NJ50
- GeneID:   2649509
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP0563
- NMPDR:   fig|257309.1.peg.530
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- ProtClustDB:   PRK14318
- BioCyc:   CDIP257309:DIP0563-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 46673; Mature: 46542

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLFGTDGVRGLANRKLTALLALKLGAAAAEVLTKDNRSTSRRPVAVVGRDPRVSGEML
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHH
AAALSAGMASRGVDVLRVGVLPTPAVAYLTDFYGADMGVVISASHNPMPDNGIKFFSKGG
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHCCC
HKLPDSVEDEIEKVMETIPDGGPTGHGIGRVIEEAVDAQETYLKHLKGAVPRSLEGITVV
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
VDCANGAASEVAPLAYAAAGAKVIPIHNHPNAYNINDSCGSTHIDQVQAAVLEHGADLGL
EECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
AHDGDADRCLAVDAEGNVVDGDQIMAILALAMKENGELHKSTLVATVMSNLGLRLAMKEA
CCCCCCCCEEEECCCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEHHC
GIELRTTKVGDRYVLEELNAGGFSLGGEQSGHIVLPDHGTTGDGTLTGLSLMSRMAETGL
CCEEEEECCCCHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
SLKVLASAMTVLPQVLINVPVSDKTIIQTHPDVVAAMERASDELGEDGRVLLRPSGTEEL
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCHHHH
FRVMVEAPSKETARRIAADLASVVAKI
HHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRLFGTDGVRGLANRKLTALLALKLGAAAAEVLTKDNRSTSRRPVAVVGRDPRVSGEML
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHH
AAALSAGMASRGVDVLRVGVLPTPAVAYLTDFYGADMGVVISASHNPMPDNGIKFFSKGG
HHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHCCC
HKLPDSVEDEIEKVMETIPDGGPTGHGIGRVIEEAVDAQETYLKHLKGAVPRSLEGITVV
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
VDCANGAASEVAPLAYAAAGAKVIPIHNHPNAYNINDSCGSTHIDQVQAAVLEHGADLGL
EECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
AHDGDADRCLAVDAEGNVVDGDQIMAILALAMKENGELHKSTLVATVMSNLGLRLAMKEA
CCCCCCCCEEEECCCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEHHC
GIELRTTKVGDRYVLEELNAGGFSLGGEQSGHIVLPDHGTTGDGTLTGLSLMSRMAETGL
CCEEEEECCCCHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
SLKVLASAMTVLPQVLINVPVSDKTIIQTHPDVVAAMERASDELGEDGRVLLRPSGTEEL
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCHHHH
FRVMVEAPSKETARRIAADLASVVAKI
HHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14602910