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The map label for this gene is 38233163

Identifier: 38233163

GI number: 38233163

Start: 522858

End: 523757

Strand: Reverse

Name: 38233163

Synonym: DIP0554

Alternate gene names: NA

Gene position: 523757-522858 (Counterclockwise)

Preceding gene: 38233164

Following gene: 38233148

Centisome position: 21.05

GC content: 53.44

Gene sequence:

>900_bases
ATGAAGACCACTGGAATTATTGCCATTGTCCTCGCCGTAGCGTGGTATTGTGCGTTACCTGAATCAGTTAGCGCTCAACA
ACGCTGTGCCGTCAGTGCGCCGCTATCGGACGAGCAACAATCCGCATCAGATCATTGGCAGGTTCTGCCTGAACTGCATC
GTATTGCTACTGGCCGTGGGGTCACTGTTGCGGTTATCGATACAGGTATTTCACCGCATCCACGCCTACCGCGGCTTATC
GACGGCGGCAGCTACCTAAGCGGCAGTTATACCCCCACGGGAGGTCTGCACGATTGTGATGCCCACGGCACAGTTGTGGC
AAGTATTATCGCTGGTCAACCTGGACCCGACCCAGTCCTCGGTGTTGCTCCGGAATCCCAGCTTATTTCTATTCAGCAAA
CCAGTAATACTGCAGCTTCAGGCACTGTGGCTTCTTTGGCTCATGCGATACATACCGCGATCGATCAGCATGCTCAGATC
ATTAATATTTCCGTTGTCTCCTGTGTTGCTAGCAATCATGCCGTTGATGATGCTGTACTCGTTGAGGCCCTCCGGCGCGC
AGAAGAATCGGGCACGGTGGTGGTATCTGCAGCGGGCAATGCCACCGGTAGCACAGATGATTGTGTTCATGGTGCTCGTG
TTTTTCCGGCGCACTACCCCACTGTGTTAACGGTCGGTGCCTTAAAGGATCCGTATCATTTCGCGGATTACTCTATGCCC
TCGCCATTCCCATTAGTTAGTGCGTTAGGTTATGTTCCAGCTGCTCTAGCTCACGACCATCCTGGTATCTCCGGAGGCAC
TCTCAACCACCGCAGCGTGTATCCCTTTCAAGGAACCAGTTTTGCGGCCCCCCTATGTTTCAGGTGTTGCTGCATTGATA
AAGCAGCGTTTCCCCGCTGA

Upstream 100 bases:

>100_bases
TCGTGTGGAATCGTTGGCAGTTGCTGCGATTGTTCCACTAGCTGCACACCTCATGGGTATTTTCTCATTGCTTCGTGGAT
TGGGTTAGGGCGATAGTCGG

Downstream 100 bases:

>100_bases
AAGCCCAGAGCACATTCGGCAAAGAATTTTGATGAGCTCAGATCCCACCGTGGGAAAAATCAACCCAGTCCATGCACTCA
CAATGGAATTTCCTGCGCCT

Product: putative subtilisin-like cell wall associated serine protease (mycosin)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKTTGIIAIVLAVAWYCALPESVSAQQRCAVSAPLSDEQQSASDHWQVLPELHRIATGRGVTVAVIDTGISPHPRLPRLI
DGGSYLSGSYTPTGGLHDCDAHGTVVASIIAGQPGPDPVLGVAPESQLISIQQTSNTAASGTVASLAHAIHTAIDQHAQI
INISVVSCVASNHAVDDAVLVEALRRAEESGTVVVSAAGNATGSTDDCVHGARVFPAHYPTVLTVGALKDPYHFADYSMP
SPFPLVSALGYVPAALAHDHPGISGGTLNHRSVYPFQGTSFAAPLCFRCCCIDKAAFPR

Sequences:

>Translated_299_residues
MKTTGIIAIVLAVAWYCALPESVSAQQRCAVSAPLSDEQQSASDHWQVLPELHRIATGRGVTVAVIDTGISPHPRLPRLI
DGGSYLSGSYTPTGGLHDCDAHGTVVASIIAGQPGPDPVLGVAPESQLISIQQTSNTAASGTVASLAHAIHTAIDQHAQI
INISVVSCVASNHAVDDAVLVEALRRAEESGTVVVSAAGNATGSTDDCVHGARVFPAHYPTVLTVGALKDPYHFADYSMP
SPFPLVSALGYVPAALAHDHPGISGGTLNHRSVYPFQGTSFAAPLCFRCCCIDKAAFPR
>Mature_299_residues
MKTTGIIAIVLAVAWYCALPESVSAQQRCAVSAPLSDEQQSASDHWQVLPELHRIATGRGVTVAVIDTGISPHPRLPRLI
DGGSYLSGSYTPTGGLHDCDAHGTVVASIIAGQPGPDPVLGVAPESQLISIQQTSNTAASGTVASLAHAIHTAIDQHAQI
INISVVSCVASNHAVDDAVLVEALRRAEESGTVVVSAAGNATGSTDDCVHGARVFPAHYPTVLTVGALKDPYHFADYSMP
SPFPLVSALGYVPAALAHDHPGISGGTLNHRSVYPFQGTSFAAPLCFRCCCIDKAAFPR

Specific function: Shows keratinolytic activity [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 30997; Mature: 30997

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTGIIAIVLAVAWYCALPESVSAQQRCAVSAPLSDEQQSASDHWQVLPELHRIATGRG
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCCCCHHHCHHHHHHHHHHHHHHHCCCC
VTVAVIDTGISPHPRLPRLIDGGSYLSGSYTPTGGLHDCDAHGTVVASIIAGQPGPDPVL
CEEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCEE
GVAPESQLISIQQTSNTAASGTVASLAHAIHTAIDQHAQIINISVVSCVASNHAVDDAVL
EECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHCCCCCHHHHH
VEALRRAEESGTVVVSAAGNATGSTDDCVHGARVFPAHYPTVLTVGALKDPYHFADYSMP
HHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCEECCCCCCCEEEECCCCCCCCCCCCCCC
SPFPLVSALGYVPAALAHDHPGISGGTLNHRSVYPFQGTSFAAPLCFRCCCIDKAAFPR
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MKTTGIIAIVLAVAWYCALPESVSAQQRCAVSAPLSDEQQSASDHWQVLPELHRIATGRG
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCCCCHHHCHHHHHHHHHHHHHHHCCCC
VTVAVIDTGISPHPRLPRLIDGGSYLSGSYTPTGGLHDCDAHGTVVASIIAGQPGPDPVL
CEEEEEECCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCEE
GVAPESQLISIQQTSNTAASGTVASLAHAIHTAIDQHAQIINISVVSCVASNHAVDDAVL
EECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHCCCCCHHHHH
VEALRRAEESGTVVVSAAGNATGSTDDCVHGARVFPAHYPTVLTVGALKDPYHFADYSMP
HHHHHHHHCCCCEEEEECCCCCCCCHHHHCCCEECCCCCCCEEEECCCCCCCCCCCCCCC
SPFPLVSALGYVPAALAHDHPGISGGTLNHRSVYPFQGTSFAAPLCFRCCCIDKAAFPR
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1369007; 11058132; 1370008 [H]