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The map label for this gene is dgoR [H]

Identifier: 38233126

GI number: 38233126

Start: 486216

End: 486977

Strand: Direct

Name: dgoR [H]

Synonym: DIP0517

Alternate gene names: 38233126

Gene position: 486216-486977 (Clockwise)

Preceding gene: 38233125

Following gene: 38233127

Centisome position: 19.54

GC content: 53.94

Gene sequence:

>762_bases
GTGAAGGATCATTCTGGGATCAGCTTCGGCAAAAACCCCACCGTCTTAGCTATCGAAAACTACATACGCGAAAACGGACT
CACGCCAGGAGACGTACTCCCCTCAGAGGCCGCAATCTGCGAGCACCTGAGCGTGTCCCGCTCCTCAGTACGAGAAGCAA
TGAGGACACTCGCCTCCCTTGACGTGGTAGAAATCCGCCACGGACACGGCACCTACGTCGGAAAAATGTCCATGGCCCCA
CTCGTCAACGGCATGGTTCTCAGGCTGACACTCAACGAAAAATCCGCGATCGAAAACCTCCAACATGTAGTAGGTATGCG
CATCGCCCTCGACCGCAGCAACGCCCAAGAACTCGCCGCCTATTACAAAGGGCGCGAAACCCCTAAGCTCGACCAAATCG
TGGAAGAAATGAAAATCCAGTTTGAGCGCGGAGAATCCTTCGAACACCAAGATTTCCTCTTCCATCAACTGCTCAACGAC
CACCTCTCCAACCCACTCATGCAGGAATTTTCCATGGCACTGTGGGAAATCCACACCCGCGTCGTGCCACGGTTGGGGTT
ACGTGATCCCGAAGACATCTCCAACACCGTCCAAGCACACGCACACATGGTAGAAGCGCTGCGTGCAGGAGACGTCGACA
AGCTGCTAGAAACCATCGACGAGCACTATCAGCCACTGCTCAGCATCCTAGAAAAGAACCGTCAATACGTCGAACAAACA
GAGCACGCAGTTGAATCCCAGAAAGGCACCCTTCACCTATGA

Upstream 100 bases:

>100_bases
ATTACTAGGGGTAAACATCACAAAAGCCCCCACAAACCAGTGATTTATCTCTCCTCAAAGTTAGTAGCAAAGTACCCCTG
TACGGAACCAAGGAGTCACC

Downstream 100 bases:

>100_bases
CACACGCACTCGGTGTCGACATCGGCGGCACTAAAATCGCAGTCGGAATCGTAGACAGCACGGACCCCACCACCGTAATC
AGCCGACACATCGTCCCCAC

Product: GntR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MKDHSGISFGKNPTVLAIENYIRENGLTPGDVLPSEAAICEHLSVSRSSVREAMRTLASLDVVEIRHGHGTYVGKMSMAP
LVNGMVLRLTLNEKSAIENLQHVVGMRIALDRSNAQELAAYYKGRETPKLDQIVEEMKIQFERGESFEHQDFLFHQLLND
HLSNPLMQEFSMALWEIHTRVVPRLGLRDPEDISNTVQAHAHMVEALRAGDVDKLLETIDEHYQPLLSILEKNRQYVEQT
EHAVESQKGTLHL

Sequences:

>Translated_253_residues
MKDHSGISFGKNPTVLAIENYIRENGLTPGDVLPSEAAICEHLSVSRSSVREAMRTLASLDVVEIRHGHGTYVGKMSMAP
LVNGMVLRLTLNEKSAIENLQHVVGMRIALDRSNAQELAAYYKGRETPKLDQIVEEMKIQFERGESFEHQDFLFHQLLND
HLSNPLMQEFSMALWEIHTRVVPRLGLRDPEDISNTVQAHAHMVEALRAGDVDKLLETIDEHYQPLLSILEKNRQYVEQT
EHAVESQKGTLHL
>Mature_253_residues
MKDHSGISFGKNPTVLAIENYIRENGLTPGDVLPSEAAICEHLSVSRSSVREAMRTLASLDVVEIRHGHGTYVGKMSMAP
LVNGMVLRLTLNEKSAIENLQHVVGMRIALDRSNAQELAAYYKGRETPKLDQIVEEMKIQFERGESFEHQDFLFHQLLND
HLSNPLMQEFSMALWEIHTRVVPRLGLRDPEDISNTVQAHAHMVEALRAGDVDKLLETIDEHYQPLLSILEKNRQYVEQT
EHAVESQKGTLHL

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=194, Percent_Identity=25.2577319587629, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28651; Mature: 28651

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDHSGISFGKNPTVLAIENYIRENGLTPGDVLPSEAAICEHLSVSRSSVREAMRTLASL
CCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DVVEIRHGHGTYVGKMSMAPLVNGMVLRLTLNEKSAIENLQHVVGMRIALDRSNAQELAA
HHHEEECCCCCEEHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHH
YYKGRETPKLDQIVEEMKIQFERGESFEHQDFLFHQLLNDHLSNPLMQEFSMALWEIHTR
HHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VVPRLGLRDPEDISNTVQAHAHMVEALRAGDVDKLLETIDEHYQPLLSILEKNRQYVEQT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHAVESQKGTLHL
HHHHHHCCCCCCC
>Mature Secondary Structure
MKDHSGISFGKNPTVLAIENYIRENGLTPGDVLPSEAAICEHLSVSRSSVREAMRTLASL
CCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DVVEIRHGHGTYVGKMSMAPLVNGMVLRLTLNEKSAIENLQHVVGMRIALDRSNAQELAA
HHHEEECCCCCEEHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHH
YYKGRETPKLDQIVEEMKIQFERGESFEHQDFLFHQLLNDHLSNPLMQEFSMALWEIHTR
HHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VVPRLGLRDPEDISNTVQAHAHMVEALRAGDVDKLLETIDEHYQPLLSILEKNRQYVEQT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHAVESQKGTLHL
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]