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The map label for this gene is cstS [H]

Identifier: 38233070

GI number: 38233070

Start: 428385

End: 429611

Strand: Direct

Name: cstS [H]

Synonym: DIP0458

Alternate gene names: 38233070

Gene position: 428385-429611 (Clockwise)

Preceding gene: 38233065

Following gene: 38233071

Centisome position: 17.21

GC content: 52.89

Gene sequence:

>1227_bases
GTGGCAACTTTTCGCTTTCTGACCCCAAGTTTTTGGATACAACTTGTTATCCAGACGATCGTAGCGTTCGTATCGTTGAG
TTTTATTAGCGCTACTGGGCTCGTAGGTAATTTTAATATTTCACCAACATGGCAGACAGTGTTGTGCATCTGCTCATATG
TGGGAATCGCGTTGACCTATGTGGGGCTCTTGCTCCAACGCTGGAAGCCGGTCAGTGGCGTGACCACGGTAACCGTCGGG
TTGATATTTGTCAGCGTCTCGCTTACGTACAACTTTTTAGCGGGATATGTGGTTGTTTGTTATGAGGCGTGGTTTATTTC
TGCACGCATCATGAGGCATCGTTCTCGTTGGCTCACCGCCTTGTTCGTAGGCAGTTTTGGCTCTATTGCTTTTAATCTGC
TGTTTCCCATCCTGTTTTTCAACGTATTGGAAACAGGGAGAGCTGTTGGGATCAAAGAGGTTATCCAGGAGCCACAAACG
TGGTTATTTGTCGCGATAGTGGTCACGCTGGTGGTGGTGTCTATCGCGTTGTTTTGGCAACTGGGGTTATCCACTAAGCG
GAAAGCTGATGAGCTGCGGGATTTGCGTGCGCGCGCGGAGCTGGCAGCGGTATCTGAACGCAACCGCATTGCGCGCGAGA
TGCATGACATTGTTGCCCATTCGCTCACGGTTGTTATTGCACAGGCAGATGGTGGCCGGTTTGCGGGTAGGGATAATCCG
CAACAAGCACTCGCAGCTTTGGAGACGATCTCTTCGGTGGGTAGGGAGGCGCTTTCTCAGATGCGTGGGTTGTTGAGCGT
GTTGCGGGAAACAGATGATCGTGACGTGACTGCAGCACCTGGTATTGAAAGCGTGGGCACGCTTATCCACGAGGCTGAGC
TTGCTGGGTTAGATATTCACTATGAGGTGGTGGGGGAGCCGCAGGCGTTGGATGAATCGCGAAGCCTGAGCGTATTTCGT
ATTGTGCAGGAGTGCCTGACTAACGTGCTCAAGCACGCGGGTACAACGCGTGCGTGGGTAGTAATGGACTGGAGTGACCC
GAGCGTGGTGCGGATCAAAGTAGACAATGAAGCGGGGGAAGCGCTGGTGGATACGCAGTCCACTGGAAAGGGGCTTGTTG
GTGTGCGGGAGCGTGCGTTGATTCATGGTGGTCGGGCGCGGTGGGGAGCGTCGATAAGCTACGTTGGGGGATGGTATGTT
GAAGCGGAAATTCCGGTGAAAGGCTAA

Upstream 100 bases:

>100_bases
CTCTGCTGGGTGACTAAGTTTTTCTCCCAAGGCCCCATTGGAACGGTTATGGCGTTGGGGTACGAACCTAGGCGAGCCTC
GCTGCGACTAGCATGAGCGT

Downstream 100 bases:

>100_bases
AACGGTGATCACTGTAGGGCTAGTGGATGACCAGCAGCTAGTGCGGGCTGGGTTTCGTATGGTGTTGGATTCGCAAAGCG
ATATCACCGTGGCGTGGGAA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MATFRFLTPSFWIQLVIQTIVAFVSLSFISATGLVGNFNISPTWQTVLCICSYVGIALTYVGLLLQRWKPVSGVTTVTVG
LIFVSVSLTYNFLAGYVVVCYEAWFISARIMRHRSRWLTALFVGSFGSIAFNLLFPILFFNVLETGRAVGIKEVIQEPQT
WLFVAIVVTLVVVSIALFWQLGLSTKRKADELRDLRARAELAAVSERNRIAREMHDIVAHSLTVVIAQADGGRFAGRDNP
QQALAALETISSVGREALSQMRGLLSVLRETDDRDVTAAPGIESVGTLIHEAELAGLDIHYEVVGEPQALDESRSLSVFR
IVQECLTNVLKHAGTTRAWVVMDWSDPSVVRIKVDNEAGEALVDTQSTGKGLVGVRERALIHGGRARWGASISYVGGWYV
EAEIPVKG

Sequences:

>Translated_408_residues
MATFRFLTPSFWIQLVIQTIVAFVSLSFISATGLVGNFNISPTWQTVLCICSYVGIALTYVGLLLQRWKPVSGVTTVTVG
LIFVSVSLTYNFLAGYVVVCYEAWFISARIMRHRSRWLTALFVGSFGSIAFNLLFPILFFNVLETGRAVGIKEVIQEPQT
WLFVAIVVTLVVVSIALFWQLGLSTKRKADELRDLRARAELAAVSERNRIAREMHDIVAHSLTVVIAQADGGRFAGRDNP
QQALAALETISSVGREALSQMRGLLSVLRETDDRDVTAAPGIESVGTLIHEAELAGLDIHYEVVGEPQALDESRSLSVFR
IVQECLTNVLKHAGTTRAWVVMDWSDPSVVRIKVDNEAGEALVDTQSTGKGLVGVRERALIHGGRARWGASISYVGGWYV
EAEIPVKG
>Mature_407_residues
ATFRFLTPSFWIQLVIQTIVAFVSLSFISATGLVGNFNISPTWQTVLCICSYVGIALTYVGLLLQRWKPVSGVTTVTVGL
IFVSVSLTYNFLAGYVVVCYEAWFISARIMRHRSRWLTALFVGSFGSIAFNLLFPILFFNVLETGRAVGIKEVIQEPQTW
LFVAIVVTLVVVSIALFWQLGLSTKRKADELRDLRARAELAAVSERNRIAREMHDIVAHSLTVVIAQADGGRFAGRDNPQ
QALAALETISSVGREALSQMRGLLSVLRETDDRDVTAAPGIESVGTLIHEAELAGLDIHYEVVGEPQALDESRSLSVFRI
VQECLTNVLKHAGTTRAWVVMDWSDPSVVRIKVDNEAGEALVDTQSTGKGLVGVRERALIHGGRARWGASISYVGGWYVE
AEIPVKG

Specific function: Member of the two-component regulatory system yfiJ/yfiK. Probably activates yfiK by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44798; Mature: 44667

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATFRFLTPSFWIQLVIQTIVAFVSLSFISATGLVGNFNISPTWQTVLCICSYVGIALTY
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHHH
VGLLLQRWKPVSGVTTVTVGLIFVSVSLTYNFLAGYVVVCYEAWFISARIMRHRSRWLTA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVGSFGSIAFNLLFPILFFNVLETGRAVGIKEVIQEPQTWLFVAIVVTLVVVSIALFWQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LGLSTKRKADELRDLRARAELAAVSERNRIAREMHDIVAHSLTVVIAQADGGRFAGRDNP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCH
QQALAALETISSVGREALSQMRGLLSVLRETDDRDVTAAPGIESVGTLIHEAELAGLDIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
YEVVGEPQALDESRSLSVFRIVQECLTNVLKHAGTTRAWVVMDWSDPSVVRIKVDNEAGE
EEECCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCC
ALVDTQSTGKGLVGVRERALIHGGRARWGASISYVGGWYVEAEIPVKG
EEECCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCCC
>Mature Secondary Structure 
ATFRFLTPSFWIQLVIQTIVAFVSLSFISATGLVGNFNISPTWQTVLCICSYVGIALTY
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHHHHHHH
VGLLLQRWKPVSGVTTVTVGLIFVSVSLTYNFLAGYVVVCYEAWFISARIMRHRSRWLTA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVGSFGSIAFNLLFPILFFNVLETGRAVGIKEVIQEPQTWLFVAIVVTLVVVSIALFWQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LGLSTKRKADELRDLRARAELAAVSERNRIAREMHDIVAHSLTVVIAQADGGRFAGRDNP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCH
QQALAALETISSVGREALSQMRGLLSVLRETDDRDVTAAPGIESVGTLIHEAELAGLDIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
YEVVGEPQALDESRSLSVFRIVQECLTNVLKHAGTTRAWVVMDWSDPSVVRIKVDNEAGE
EEECCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCC
ALVDTQSTGKGLVGVRERALIHGGRARWGASISYVGGWYVEAEIPVKG
EEECCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8973323; 9384377 [H]