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The map label for this gene is ydaB [H]

Identifier: 38232974

GI number: 38232974

Start: 323875

End: 325527

Strand: Reverse

Name: ydaB [H]

Synonym: DIP0358

Alternate gene names: 38232974

Gene position: 325527-323875 (Counterclockwise)

Preceding gene: 38232976

Following gene: 38232972

Centisome position: 13.08

GC content: 61.95

Gene sequence:

>1653_bases
ATGCCCCAGATTGCGCCACTGCTGACAACGCTGACGTCGATGGCACGCCACATGCCCACGATCGCCGCATCAGGGCTCCT
CAGCACCGAGGGCAAACCCCTCGCAGCGCTGAGCACTCCAGCCACCATGGCACGCTATCGCTTCACCACCGCACGTGAAG
TAGAACAAGCAGCCCGCGTCTGCCCCGACCGCATCGCGCTTATCGACGACGACGGCAGCCTCACCTACCAAGAACTCCGC
GACAACTCCCGCGCCCTAGCCCGCTACTTTTACCAGCTCAATAGCAAGGACCTCCGCATCGGCGTGATGGCCCGCAACGG
CCGCGGCAGCATCTACCCGCTCACCGCCAAAGGCTACGCAGGCGCCTCCATCTACCTGCTCAACATCGGATCCTCCCGCG
ACCAACTCGACGGCTGCATCCGCCGCGACGGCATCAACCTGCTCGTCATCGACGAAGAATTCCTGCCACGCCTCCCCGAA
AACATCCAGATCCCTGTGATCGTGGCGCACCGCGAAGCCGAACCGCACCCCCGCGCTGCGGAATGCCTTGACCTAGAGGA
GATCGTCGCAACGCACACCAGCGGAAACCTGCCCGTTTTCCCCCAACACGGCGCCATTGTGCTCATGTCCTCCGGCACCA
CCGGTATCCCCAAGGGCGTCATGCGCAACGAGCCTAAAGCCCCCACAATCCTAGGCGCTGTACTCAGCGAGATTCCGTTC
CGCACCAACATGAACGTCCAGCTCACCGCATCGGTGTTCCACACCTGGGGTTGGGGAATCTTGAATCTGAGCTTCGCGAT
GCGCTGCACCGTGGTCACCCGCCGAATCTTCGACCCCGAACGCACGCTTCGCGACGTCGAACGCTTCAAAATCCATGCGA
TGATCTCCTCCCCGATCTTCCTCAAGCGCTTCTTCGAAGTCGAAGGCCAAGAAGACATCGACTGCTCCAGCCTCGAGTTC
ATCTTCTCCTCCGGTCACGCCCTATCCCCATGGCTCGTCGAGGCCGTCCACAACCGCTTTGGCAAAATCCTGTGCAACCT
TTACGGCAGCACCGAGATCTCCGCAGCGGCCATCGCCAACATGGAAGAAGTGGCAAAGAACCCCACCGTTGCCGGCAAGA
TCTGCGAAGGCACCACCGTCCGCATCCTCGACGACAACGACCAACCCGTTCCCGCCGGAACCGTCGGCCGAATCTTCTGC
TACAACAACACCACCCTTAACGGCTACACCGACCCCCGCATCCCCATTAAGCGCGTCGGCGAACTCGTCCAGATCGGCGA
CCGCGGCTACATCGACGAACGCGGCCTGCTGTACGTGCTCGGCCGCGCTGACGACATGATCATCGTCGGCGGCGAAAACG
TCTTCCCACGGTCCGTAGAAGAAGTTCTCGAACCCATGCCAGGTATCCAAGACCTCTACGCCAGTGGTGTGGACGACGAT
GAAACCTTCGCCCGAATCGCCGTGTGGATCGTCAAAAGCCCCACCGCCGCAGGCGAGGCGCTGACCGAAGACGCCGTCCG
CGACTGGGTACGCACCAAGCTTGCCGACCACTCCATCCCCCGCGATGTACACTTCATCGACGAGCTCCCCCGCAACGCCA
CCGGCAAAGTAATGCCGCGCATGCTGCCAGGGATTTCCCACCCCACCGCATAA

Upstream 100 bases:

>100_bases
CAAAGTTAAAGATGTTATCAAATGGAGCGTAACATCGGGGTCACTTCTGCATATAAACCGCTATGCCATACAAATTGTCT
TTTATAGGAGTTTTCCTTAC

Downstream 100 bases:

>100_bases
GAAAAAGCCGAGGCCCTAGTGCCTCGGCTTTATTGGTTAGCGGCAATTCTTAAACCACGTGCAGTTAAACAACAAGGCAA
AGAGTGCCATGATGCCGCCT

Product: acyl-CoA synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MPQIAPLLTTLTSMARHMPTIAASGLLSTEGKPLAALSTPATMARYRFTTAREVEQAARVCPDRIALIDDDGSLTYQELR
DNSRALARYFYQLNSKDLRIGVMARNGRGSIYPLTAKGYAGASIYLLNIGSSRDQLDGCIRRDGINLLVIDEEFLPRLPE
NIQIPVIVAHREAEPHPRAAECLDLEEIVATHTSGNLPVFPQHGAIVLMSSGTTGIPKGVMRNEPKAPTILGAVLSEIPF
RTNMNVQLTASVFHTWGWGILNLSFAMRCTVVTRRIFDPERTLRDVERFKIHAMISSPIFLKRFFEVEGQEDIDCSSLEF
IFSSGHALSPWLVEAVHNRFGKILCNLYGSTEISAAAIANMEEVAKNPTVAGKICEGTTVRILDDNDQPVPAGTVGRIFC
YNNTTLNGYTDPRIPIKRVGELVQIGDRGYIDERGLLYVLGRADDMIIVGGENVFPRSVEEVLEPMPGIQDLYASGVDDD
ETFARIAVWIVKSPTAAGEALTEDAVRDWVRTKLADHSIPRDVHFIDELPRNATGKVMPRMLPGISHPTA

Sequences:

>Translated_550_residues
MPQIAPLLTTLTSMARHMPTIAASGLLSTEGKPLAALSTPATMARYRFTTAREVEQAARVCPDRIALIDDDGSLTYQELR
DNSRALARYFYQLNSKDLRIGVMARNGRGSIYPLTAKGYAGASIYLLNIGSSRDQLDGCIRRDGINLLVIDEEFLPRLPE
NIQIPVIVAHREAEPHPRAAECLDLEEIVATHTSGNLPVFPQHGAIVLMSSGTTGIPKGVMRNEPKAPTILGAVLSEIPF
RTNMNVQLTASVFHTWGWGILNLSFAMRCTVVTRRIFDPERTLRDVERFKIHAMISSPIFLKRFFEVEGQEDIDCSSLEF
IFSSGHALSPWLVEAVHNRFGKILCNLYGSTEISAAAIANMEEVAKNPTVAGKICEGTTVRILDDNDQPVPAGTVGRIFC
YNNTTLNGYTDPRIPIKRVGELVQIGDRGYIDERGLLYVLGRADDMIIVGGENVFPRSVEEVLEPMPGIQDLYASGVDDD
ETFARIAVWIVKSPTAAGEALTEDAVRDWVRTKLADHSIPRDVHFIDELPRNATGKVMPRMLPGISHPTA
>Mature_549_residues
PQIAPLLTTLTSMARHMPTIAASGLLSTEGKPLAALSTPATMARYRFTTAREVEQAARVCPDRIALIDDDGSLTYQELRD
NSRALARYFYQLNSKDLRIGVMARNGRGSIYPLTAKGYAGASIYLLNIGSSRDQLDGCIRRDGINLLVIDEEFLPRLPEN
IQIPVIVAHREAEPHPRAAECLDLEEIVATHTSGNLPVFPQHGAIVLMSSGTTGIPKGVMRNEPKAPTILGAVLSEIPFR
TNMNVQLTASVFHTWGWGILNLSFAMRCTVVTRRIFDPERTLRDVERFKIHAMISSPIFLKRFFEVEGQEDIDCSSLEFI
FSSGHALSPWLVEAVHNRFGKILCNLYGSTEISAAAIANMEEVAKNPTVAGKICEGTTVRILDDNDQPVPAGTVGRIFCY
NNTTLNGYTDPRIPIKRVGELVQIGDRGYIDERGLLYVLGRADDMIIVGGENVFPRSVEEVLEPMPGIQDLYASGVDDDE
TFARIAVWIVKSPTAAGEALTEDAVRDWVRTKLADHSIPRDVHFIDELPRNATGKVMPRMLPGISHPTA

Specific function: Unknown

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=544, Percent_Identity=23.1617647058824, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI115511026, Length=359, Percent_Identity=25.3481894150418, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI42544132, Length=402, Percent_Identity=24.1293532338308, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI122937307, Length=366, Percent_Identity=25.9562841530055, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI13375727, Length=531, Percent_Identity=22.0338983050847, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI38505220, Length=353, Percent_Identity=25.2124645892351, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI157311624, Length=362, Percent_Identity=24.0331491712707, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI157311622, Length=362, Percent_Identity=24.0331491712707, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI58082049, Length=357, Percent_Identity=24.9299719887955, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI28416953, Length=546, Percent_Identity=22.7106227106227, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI145693145, Length=510, Percent_Identity=25.4901960784314, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788107, Length=530, Percent_Identity=23.0188679245283, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI221142682, Length=222, Percent_Identity=28.8288288288288, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786801, Length=446, Percent_Identity=24.2152466367713, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786810, Length=514, Percent_Identity=23.5408560311284, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790505, Length=362, Percent_Identity=21.8232044198895, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786529, Length=405, Percent_Identity=23.2098765432099, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559526, Length=517, Percent_Identity=24.1779497098646, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17558820, Length=353, Percent_Identity=27.1954674220963, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32563687, Length=493, Percent_Identity=23.7322515212982, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17557194, Length=386, Percent_Identity=26.1658031088083, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538037, Length=369, Percent_Identity=26.8292682926829, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17560308, Length=523, Percent_Identity=22.1797323135755, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994694, Length=542, Percent_Identity=22.6937269372694, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71994703, Length=542, Percent_Identity=22.6937269372694, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71994690, Length=357, Percent_Identity=24.3697478991597, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17531443, Length=518, Percent_Identity=21.042471042471, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319699, Length=347, Percent_Identity=27.0893371757925, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24648253, Length=481, Percent_Identity=25.1559251559252, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21356441, Length=474, Percent_Identity=24.6835443037975, Blast_Score=109, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24648255, Length=481, Percent_Identity=25.1559251559252, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24648260, Length=345, Percent_Identity=27.2463768115942, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281365686, Length=472, Percent_Identity=24.5762711864407, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24653035, Length=343, Percent_Identity=23.9067055393586, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI19922652, Length=358, Percent_Identity=25.6983240223464, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24581924, Length=380, Percent_Identity=21.5789473684211, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20130357, Length=493, Percent_Identity=21.9066937119675, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161076582, Length=352, Percent_Identity=23.5795454545455, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24648257, Length=346, Percent_Identity=24.8554913294798, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24656500, Length=359, Percent_Identity=25.6267409470752, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648676, Length=369, Percent_Identity=26.0162601626016, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356947, Length=349, Percent_Identity=25.5014326647564, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21358303, Length=468, Percent_Identity=22.6495726495727, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI18859661, Length=503, Percent_Identity=23.8568588469185, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21355181, Length=511, Percent_Identity=22.5048923679061, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 60590; Mature: 60459

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQIAPLLTTLTSMARHMPTIAASGLLSTEGKPLAALSTPATMARYRFTTAREVEQAARV
CCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEEECCCHHHHHEECHHHHHHHHHHHC
CPDRIALIDDDGSLTYQELRDNSRALARYFYQLNSKDLRIGVMARNGRGSIYPLTAKGYA
CCCEEEEEECCCCEEHHHHHCCHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCC
GASIYLLNIGSSRDQLDGCIRRDGINLLVIDEEFLPRLPENIQIPVIVAHREAEPHPRAA
CCEEEEEECCCCHHHHHHHHHHCCCEEEEECHHHHCCCCCCCEEEEEEEECCCCCCCCHH
ECLDLEEIVATHTSGNLPVFPQHGAIVLMSSGTTGIPKGVMRNEPKAPTILGAVLSEIPF
HHCCHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHCCC
RTNMNVQLTASVFHTWGWGILNLSFAMRCTVVTRRIFDPERTLRDVERFKIHAMISSPIF
CCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEECCCHH
LKRFFEVEGQEDIDCSSLEFIFSSGHALSPWLVEAVHNRFGKILCNLYGSTEISAAAIAN
HHHHHHCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHC
MEEVAKNPTVAGKICEGTTVRILDDNDQPVPAGTVGRIFCYNNTTLNGYTDPRIPIKRVG
HHHHHCCCCCEEEECCCCEEEEECCCCCCCCCCCCEEEEEECCCEECCCCCCCCCHHHHH
ELVQIGDRGYIDERGLLYVLGRADDMIIVGGENVFPRSVEEVLEPMPGIQDLYASGVDDD
HHHEECCCCCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCCCC
ETFARIAVWIVKSPTAAGEALTEDAVRDWVRTKLADHSIPRDVHFIDELPRNATGKVMPR
HHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHH
MLPGISHPTA
HCCCCCCCCC
>Mature Secondary Structure 
PQIAPLLTTLTSMARHMPTIAASGLLSTEGKPLAALSTPATMARYRFTTAREVEQAARV
CCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEEECCCHHHHHEECHHHHHHHHHHHC
CPDRIALIDDDGSLTYQELRDNSRALARYFYQLNSKDLRIGVMARNGRGSIYPLTAKGYA
CCCEEEEEECCCCEEHHHHHCCHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCC
GASIYLLNIGSSRDQLDGCIRRDGINLLVIDEEFLPRLPENIQIPVIVAHREAEPHPRAA
CCEEEEEECCCCHHHHHHHHHHCCCEEEEECHHHHCCCCCCCEEEEEEEECCCCCCCCHH
ECLDLEEIVATHTSGNLPVFPQHGAIVLMSSGTTGIPKGVMRNEPKAPTILGAVLSEIPF
HHCCHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHCCC
RTNMNVQLTASVFHTWGWGILNLSFAMRCTVVTRRIFDPERTLRDVERFKIHAMISSPIF
CCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEECCCHH
LKRFFEVEGQEDIDCSSLEFIFSSGHALSPWLVEAVHNRFGKILCNLYGSTEISAAAIAN
HHHHHHCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHC
MEEVAKNPTVAGKICEGTTVRILDDNDQPVPAGTVGRIFCYNNTTLNGYTDPRIPIKRVG
HHHHHCCCCCEEEECCCCEEEEECCCCCCCCCCCCEEEEEECCCEECCCCCCCCCHHHHH
ELVQIGDRGYIDERGLLYVLGRADDMIIVGGENVFPRSVEEVLEPMPGIQDLYASGVDDD
HHHEECCCCCCCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCCCC
ETFARIAVWIVKSPTAAGEALTEDAVRDWVRTKLADHSIPRDVHFIDELPRNATGKVMPR
HHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHH
MLPGISHPTA
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]