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The map label for this gene is yprA [H]

Identifier: 38232940

GI number: 38232940

Start: 283045

End: 285381

Strand: Reverse

Name: yprA [H]

Synonym: DIP0319

Alternate gene names: 38232940

Gene position: 285381-283045 (Counterclockwise)

Preceding gene: 38232947

Following gene: 38232932

Centisome position: 11.47

GC content: 60.16

Gene sequence:

>2337_bases
ATGAGCAGTAGTAGCCCCTTTATGGGGTACCAATTGGGCGAAGAACTCGCCGAATCCGTGGCACAGCGTTACCCCAATTC
CACGTGCACGCACATCGAAAACATCCCGCCGCGTAGCGCCCACTACCTGCCATGGCCTGCATGGACAGCACCTGAGCTAC
AACGCGAGTTGGAACGTCGCGGCATCGCGCAGCTGTACTCCCACCAAGCCCAGGCGGCTGATCTAGCGTGGACTGGCACC
AATGTTGTGGTTGCCACTGGTACATCGTCGGGAAAATCATTGAGTTACCTGCTGCCGATCCTCTCGGCAATGAGTCAAGA
TCCGCAGGCCTGTGCGCTGTATCTCACCCCCACCAAAGCTTTAGGTTCTGACCAGCTTGCCCACGTGATGTCGCTTGTGG
GAAACGTGGATACCCTCACAGGGGTTCACCCCGCACCTTACGACGGCGACACTCCCACCGATGCCCGCGCCGGCATCCGC
GAACAATCCCGTTTCGTATTTTCCAATCCCGATATGCTGCACACAGGCATTTTGCCAAACCATCAGCGATGGGCCAGATT
CTTTCGACACCTTCGATTCATCGTGATCGATGAGTGTCACTCTTACCGTGGCGTTTTCGGCGCTGGTGTAGCGCTGGTTA
TCCGCCGACTCCTGCGCCTCGCCGCGCGCTACGGCAGCACTCCCACAGTCATGCTGGCGTCGGCCACCAGCAACGATCCC
GCGGCCCATGCCAGCACGCTCATTGGTCAACCCGTCGTTGCTGTCACCGAGGACGGTGCCCCCACGGGGGCGCGCACTGT
CATGCTGTGGGAGCCGGGGTTTGTCGATGGTGCAGAGGGAGAAAACGGCGCTCCGATTCGTCGTGCCGCATCCACGGAGT
CGGCGGGCATCATGGCCACGCTCATCGCTGCAGGTGCGCGCACGTTGACCTTCGTGCGCTCGCGCAGGCAGGCTGAGGTG
GTGGCACTGCGCTGCGCCGAAGAGCTCGCCTGCCATGGCCGACACGATTTTGCTTCGCGAGTTGCAGCGTATCGCGCAGG
CTACCTCGCCGAGGATCGTAGGGCACTTGAACGCAAGCTTGACGACGGCACCCTACTGGGCGTGGCCAGCACTAATGCTC
TGGAGCTTGGCATTGACGTTGGTGGCCTCGACGCCGTGGTGACCGCCGGCTACCCAGGCACCGTTGCCAGTTTTTGGCAG
CAGGCAGGTCGCGCCGGCAGACGTGGCCAAGGTTCGCTAGTCACCTTGGTTGCCCGCGATGATCCCATGGACACCTATCT
TGTTCACCACCCCGAGGCTTTGTTGGGTCGACCGATGGAAAAGATCGTGTTCGACCCCCACAATCCGCATATTTTAAGTG
GCCACCTGTATTGCGCTGCGGCAGAATCCCCGCTCACAGAAGCCGAGATCGACGCATTAAACGCACGTGAGGTAGCCCAG
CAGTTAGCTCACGACGGCTACCTGCGCCACCGCCCTACCGGATGGTTTGCAGTAGAACAACCAGGCCAGCCCCCTGCCCA
TTCCTTGGTTAGCCTGCGCGGCAGCGGCCACCATGTTGCCATCGTGGATCGTAGCGATGGCCGCCTCCTGGGCACCATTG
ACAGTGCGCGTGCAGCCTCCCAAGTCCATCCCGGCGCGGTATATCTGCACCAAGGCGAGACTTTTGTTATCGAAGAGCTT
GATGACCAAGTGGCGTTGGCGGTTCCAGATCAGCCGGATTATCAGACGTTTGCGCGTTCCACCACTGATATTCGCATTGT
GGGCGAGGTGGATAAGGTGTGTAATCCAGCTCCCGGCCTGTGGGTATCCAACTTGGTGGTGGAGGTTACCGACCGCGTGG
TGGGTTACACCATGAAGGCGTCTGATGGGTCTGTGCTGGCAATGGTGCCGCTGCAGATGCCACCGCAGACATTGGTTACT
CGTGCGGTGGCATACACCGTTGATCCTCTCGTGTTGGACTCGTTGGGCATTACCGACGTTCCCGGTGCGCTGCATGCCGC
TGAACATGCGGCGATCGGTTTGTTGCCGCTTATTGCCACGTGTGACCGATGGGATATTGGCGGGGTTTCAACCGCGGAGC
ATCCCGATACTGGCCTGCCCACAGTGTTCGTCTACGACGGCCACCCAGGGGGTGCTGGGTTTGCTGACTGCGGTTACGAG
CGCTTCCCCGAGTGGGTTGCCACCACGTTTGAGGCTATCCGTTCCTGCCAGTGCGAGTCGGGATGCCCGTCGTGTGTGCA
ATCACCCAAGTGTGGCAATGGCAATGATCCGTTGAGCAAGGAGGGTGCCATTGCGTTACTGGGGGCTATGTGCACAATGT
TGGGTGTTACTCCCTGA

Upstream 100 bases:

>100_bases
CGACCAGACCCAAGTGTGTCACGTTTTCCCAAACAAAAACAGGGATTTTTCTCAACTGGTAGATTGTTGCAGGTCAGCAT
GGACGAGGCAAAGGTCACAC

Downstream 100 bases:

>100_bases
GGGGCCCAGCACGTGCAGTTGCGCGCTGCTCTCGCACGGACGTGGTGAGTTCCACATCCTCGCCATCGATTGTGCACTCG
GCTAGTTCTGCGTGATGAGC

Product: ATP-dependent RNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 778; Mature: 777

Protein sequence:

>778_residues
MSSSSPFMGYQLGEELAESVAQRYPNSTCTHIENIPPRSAHYLPWPAWTAPELQRELERRGIAQLYSHQAQAADLAWTGT
NVVVATGTSSGKSLSYLLPILSAMSQDPQACALYLTPTKALGSDQLAHVMSLVGNVDTLTGVHPAPYDGDTPTDARAGIR
EQSRFVFSNPDMLHTGILPNHQRWARFFRHLRFIVIDECHSYRGVFGAGVALVIRRLLRLAARYGSTPTVMLASATSNDP
AAHASTLIGQPVVAVTEDGAPTGARTVMLWEPGFVDGAEGENGAPIRRAASTESAGIMATLIAAGARTLTFVRSRRQAEV
VALRCAEELACHGRHDFASRVAAYRAGYLAEDRRALERKLDDGTLLGVASTNALELGIDVGGLDAVVTAGYPGTVASFWQ
QAGRAGRRGQGSLVTLVARDDPMDTYLVHHPEALLGRPMEKIVFDPHNPHILSGHLYCAAAESPLTEAEIDALNAREVAQ
QLAHDGYLRHRPTGWFAVEQPGQPPAHSLVSLRGSGHHVAIVDRSDGRLLGTIDSARAASQVHPGAVYLHQGETFVIEEL
DDQVALAVPDQPDYQTFARSTTDIRIVGEVDKVCNPAPGLWVSNLVVEVTDRVVGYTMKASDGSVLAMVPLQMPPQTLVT
RAVAYTVDPLVLDSLGITDVPGALHAAEHAAIGLLPLIATCDRWDIGGVSTAEHPDTGLPTVFVYDGHPGGAGFADCGYE
RFPEWVATTFEAIRSCQCESGCPSCVQSPKCGNGNDPLSKEGAIALLGAMCTMLGVTP

Sequences:

>Translated_778_residues
MSSSSPFMGYQLGEELAESVAQRYPNSTCTHIENIPPRSAHYLPWPAWTAPELQRELERRGIAQLYSHQAQAADLAWTGT
NVVVATGTSSGKSLSYLLPILSAMSQDPQACALYLTPTKALGSDQLAHVMSLVGNVDTLTGVHPAPYDGDTPTDARAGIR
EQSRFVFSNPDMLHTGILPNHQRWARFFRHLRFIVIDECHSYRGVFGAGVALVIRRLLRLAARYGSTPTVMLASATSNDP
AAHASTLIGQPVVAVTEDGAPTGARTVMLWEPGFVDGAEGENGAPIRRAASTESAGIMATLIAAGARTLTFVRSRRQAEV
VALRCAEELACHGRHDFASRVAAYRAGYLAEDRRALERKLDDGTLLGVASTNALELGIDVGGLDAVVTAGYPGTVASFWQ
QAGRAGRRGQGSLVTLVARDDPMDTYLVHHPEALLGRPMEKIVFDPHNPHILSGHLYCAAAESPLTEAEIDALNAREVAQ
QLAHDGYLRHRPTGWFAVEQPGQPPAHSLVSLRGSGHHVAIVDRSDGRLLGTIDSARAASQVHPGAVYLHQGETFVIEEL
DDQVALAVPDQPDYQTFARSTTDIRIVGEVDKVCNPAPGLWVSNLVVEVTDRVVGYTMKASDGSVLAMVPLQMPPQTLVT
RAVAYTVDPLVLDSLGITDVPGALHAAEHAAIGLLPLIATCDRWDIGGVSTAEHPDTGLPTVFVYDGHPGGAGFADCGYE
RFPEWVATTFEAIRSCQCESGCPSCVQSPKCGNGNDPLSKEGAIALLGAMCTMLGVTP
>Mature_777_residues
SSSSPFMGYQLGEELAESVAQRYPNSTCTHIENIPPRSAHYLPWPAWTAPELQRELERRGIAQLYSHQAQAADLAWTGTN
VVVATGTSSGKSLSYLLPILSAMSQDPQACALYLTPTKALGSDQLAHVMSLVGNVDTLTGVHPAPYDGDTPTDARAGIRE
QSRFVFSNPDMLHTGILPNHQRWARFFRHLRFIVIDECHSYRGVFGAGVALVIRRLLRLAARYGSTPTVMLASATSNDPA
AHASTLIGQPVVAVTEDGAPTGARTVMLWEPGFVDGAEGENGAPIRRAASTESAGIMATLIAAGARTLTFVRSRRQAEVV
ALRCAEELACHGRHDFASRVAAYRAGYLAEDRRALERKLDDGTLLGVASTNALELGIDVGGLDAVVTAGYPGTVASFWQQ
AGRAGRRGQGSLVTLVARDDPMDTYLVHHPEALLGRPMEKIVFDPHNPHILSGHLYCAAAESPLTEAEIDALNAREVAQQ
LAHDGYLRHRPTGWFAVEQPGQPPAHSLVSLRGSGHHVAIVDRSDGRLLGTIDSARAASQVHPGAVYLHQGETFVIEELD
DQVALAVPDQPDYQTFARSTTDIRIVGEVDKVCNPAPGLWVSNLVVEVTDRVVGYTMKASDGSVLAMVPLQMPPQTLVTR
AVAYTVDPLVLDSLGITDVPGALHAAEHAAIGLLPLIATCDRWDIGGVSTAEHPDTGLPTVFVYDGHPGGAGFADCGYER
FPEWVATTFEAIRSCQCESGCPSCVQSPKCGNGNDPLSKEGAIALLGAMCTMLGVTP

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320497, Length=792, Percent_Identity=33.3333333333333, Blast_Score=413, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 83073; Mature: 82941

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSSPFMGYQLGEELAESVAQRYPNSTCTHIENIPPRSAHYLPWPAWTAPELQRELERR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
GIAQLYSHQAQAADLAWTGTNVVVATGTSSGKSLSYLLPILSAMSQDPQACALYLTPTKA
HHHHHHHHHHHHCCEEEECCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCHH
LGSDQLAHVMSLVGNVDTLTGVHPAPYDGDTPTDARAGIREQSRFVFSNPDMLHTGILPN
CCCHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHCCHHHCCEEECCCCEEEECCCCC
HQRWARFFRHLRFIVIDECHSYRGVFGAGVALVIRRLLRLAARYGSTPTVMLASATSNDP
HHHHHHHHHHHHEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
AAHASTLIGQPVVAVTEDGAPTGARTVMLWEPGFVDGAEGENGAPIRRAASTESAGIMAT
HHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHCCCCCCCHHHHH
LIAAGARTLTFVRSRRQAEVVALRCAEELACHGRHDFASRVAAYRAGYLAEDRRALERKL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHC
DDGTLLGVASTNALELGIDVGGLDAVVTAGYPGTVASFWQQAGRAGRRGQGSLVTLVARD
CCCEEEEEECCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEECC
DPMDTYLVHHPEALLGRPMEKIVFDPHNPHILSGHLYCAAAESPLTEAEIDALNAREVAQ
CCCCCEEEECCHHHHCCCCHHHEECCCCCEEEECEEEEEECCCCCCHHHHHHCCHHHHHH
QLAHDGYLRHRPTGWFAVEQPGQPPAHSLVSLRGSGHHVAIVDRSDGRLLGTIDSARAAS
HHHHCCCEEECCCCEEEECCCCCCCHHHHHEECCCCCEEEEEECCCCCEEEECHHHHHHH
QVHPGAVYLHQGETFVIEELDDQVALAVPDQPDYQTFARSTTDIRIVGEVDKVCNPAPGL
CCCCCEEEEECCCEEEEEECCCCEEEECCCCCCHHHHHCCCCCEEEEECHHHHCCCCCCH
WVSNLVVEVTDRVVGYTMKASDGSVLAMVPLQMPPQTLVTRAVAYTVDPLVLDSLGITDV
HHHHHHHHHHHHHHEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHCCCCCCCC
PGALHAAEHAAIGLLPLIATCDRWDIGGVSTAEHPDTGLPTVFVYDGHPGGAGFADCGYE
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHCCHH
RFPEWVATTFEAIRSCQCESGCPSCVQSPKCGNGNDPLSKEGAIALLGAMCTMLGVTP
HHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSSSPFMGYQLGEELAESVAQRYPNSTCTHIENIPPRSAHYLPWPAWTAPELQRELERR
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
GIAQLYSHQAQAADLAWTGTNVVVATGTSSGKSLSYLLPILSAMSQDPQACALYLTPTKA
HHHHHHHHHHHHCCEEEECCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCHH
LGSDQLAHVMSLVGNVDTLTGVHPAPYDGDTPTDARAGIREQSRFVFSNPDMLHTGILPN
CCCHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHCCHHHCCEEECCCCEEEECCCCC
HQRWARFFRHLRFIVIDECHSYRGVFGAGVALVIRRLLRLAARYGSTPTVMLASATSNDP
HHHHHHHHHHHHEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
AAHASTLIGQPVVAVTEDGAPTGARTVMLWEPGFVDGAEGENGAPIRRAASTESAGIMAT
HHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHCCCCCCCHHHHH
LIAAGARTLTFVRSRRQAEVVALRCAEELACHGRHDFASRVAAYRAGYLAEDRRALERKL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHC
DDGTLLGVASTNALELGIDVGGLDAVVTAGYPGTVASFWQQAGRAGRRGQGSLVTLVARD
CCCEEEEEECCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEECC
DPMDTYLVHHPEALLGRPMEKIVFDPHNPHILSGHLYCAAAESPLTEAEIDALNAREVAQ
CCCCCEEEECCHHHHCCCCHHHEECCCCCEEEECEEEEEECCCCCCHHHHHHCCHHHHHH
QLAHDGYLRHRPTGWFAVEQPGQPPAHSLVSLRGSGHHVAIVDRSDGRLLGTIDSARAAS
HHHHCCCEEECCCCEEEECCCCCCCHHHHHEECCCCCEEEEEECCCCCEEEECHHHHHHH
QVHPGAVYLHQGETFVIEELDDQVALAVPDQPDYQTFARSTTDIRIVGEVDKVCNPAPGL
CCCCCEEEEECCCEEEEEECCCCEEEECCCCCCHHHHHCCCCCEEEEECHHHHCCCCCCH
WVSNLVVEVTDRVVGYTMKASDGSVLAMVPLQMPPQTLVTRAVAYTVDPLVLDSLGITDV
HHHHHHHHHHHHHHEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHCCCCCCCC
PGALHAAEHAAIGLLPLIATCDRWDIGGVSTAEHPDTGLPTVFVYDGHPGGAGFADCGYE
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHCCHH
RFPEWVATTFEAIRSCQCESGCPSCVQSPKCGNGNDPLSKEGAIALLGAMCTMLGVTP
HHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]