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The map label for this gene is glpT [H]

Identifier: 38232906

GI number: 38232906

Start: 252957

End: 254327

Strand: Reverse

Name: glpT [H]

Synonym: DIP0285

Alternate gene names: 38232906

Gene position: 254327-252957 (Counterclockwise)

Preceding gene: 38232907

Following gene: 38232905

Centisome position: 10.22

GC content: 51.13

Gene sequence:

>1371_bases
ATGTTTGCTTGGTTGCAAGCCCCCGGCCCTGCTGCCCCGCTGTCGGCGGAGCAGGTGGATCGCACCTACCCACGGATGCG
TCTGCAGGTGTTCATGGGTATTTTCTTGGGCTATGCGGGTTTTTATTTGATCCGTAATAATATTTCGGCGATTGCCCCGT
TGCTTATTGATGAAAGTGGTGCGATTGATAAGCCGGCGATCGGCATTATTGGTAATGCTGTGTTGGTCAGCTATGGCCTG
TCTAAGTTCTTTAGTGCCATGGTGTCGGATCGTTCTAATGCTCGCTATTTCTTGCCGCTGGGCTTGGCACTGTCGGCGCT
GATGAACTTGGTAGTTGCGTTTGTGCCGTGGGTTTCGGCCAGCGTGGGCGTGTTCGCTACGGTGATGTTCCTTAATGGTT
GGTTCCAAGGCATGGGTTACCCTCCTTGTGGCCGTATTGTGGTGCAGTGGTTCTCTACTAGTGAGCGCGGTTGGAAGGGT
TCGTTGTGGAACACTTCTCACAACTTGGGTGCTTTTGGTTTGCCAGTGTTGGTCGGTATTGGTTTGAGCATGACGGGCGA
GAATTGGCGTGCTGCTTACTGGCTTCCTGCGTTGGTTGCTTTGGTTGTCGCGTTGGTTGCGTTCTTGCTTATTCGTGATA
ATCCTCAGTCTGTTGGTTTGCCGCCTATCGACGACTACCGCAACGATCCTGCGAAGGTTGCGGAGGATACGGGCGAGAAG
ATTTCGACGAAGGATTTGGTGTTCAAGCATATTTTGCACAGCCGCATCATTATGCTGTTGGCCATTGCGAATGTGTTTGT
TTATGCCTTGCGTTATGGTGTTTTGCACTGGATTACCACGTACTTGTCTGAGCAGCACCACATGAGCATTGGTAGCGGTC
TGATTGGTTTTGCTGCTTTCGAGTTGGCTGGCTTTATTGGCACGGTTTTGTGCGGTTGGTTGTCGGACAATGTGTTTAAG
GGCAATCGTTCTGCTGCTATTTCGTTGTTCACCTTGGGCGCTGGTTTGTCTATCGCTGCATACTGGTTGGCTCCTGTGGG
TACGCCGTTCTGGTTGATGGTTATTTTCGTTGCCTTTATTGGTGGTTTTATCTACGGTCCTGTTGGCTTGATCGGTTTGC
AGGCATTGGATCTTTCACCTCGTAACGTGGCTGGTACCGCTGCTGGCTTCACGGGCTTGTTCGGTTACCTGCTGGGTGCA
ACCTTGGCTTCGACTGGTGTGGGCTTCTTGGTTAAGTTCGCTGGTTGGAATGTCACGTTCATTGTGTTCTTGGTCTTTAC
GGTTTTGATTCTGGTTATTTTCCAGGTGATCTGGCGCGAGGAGAAGAAGTTGATGCAGGAGCGTGCTTTGAAGCTCGAGC
AGGGTGTTTAG

Upstream 100 bases:

>100_bases
CTGTTACCAATTGTTACCGCTATGGTCACTATGGTTACCGAGCGCGGAGCACAATCGCAATTAGTTGATAAAAGTGATTG
TGCACAAAGGAGTGCCTCGT

Downstream 100 bases:

>100_bases
TTCCTGACTAGGAGAAGCGCTGGGGAGGAATTCCCCAGCGCTTTTGTTATCGTTGAGCGTGGACGCGAAGGAGAACCATA
GTGTTATCAAAATGGTTACG

Product: putative glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MFAWLQAPGPAAPLSAEQVDRTYPRMRLQVFMGIFLGYAGFYLIRNNISAIAPLLIDESGAIDKPAIGIIGNAVLVSYGL
SKFFSAMVSDRSNARYFLPLGLALSALMNLVVAFVPWVSASVGVFATVMFLNGWFQGMGYPPCGRIVVQWFSTSERGWKG
SLWNTSHNLGAFGLPVLVGIGLSMTGENWRAAYWLPALVALVVALVAFLLIRDNPQSVGLPPIDDYRNDPAKVAEDTGEK
ISTKDLVFKHILHSRIIMLLAIANVFVYALRYGVLHWITTYLSEQHHMSIGSGLIGFAAFELAGFIGTVLCGWLSDNVFK
GNRSAAISLFTLGAGLSIAAYWLAPVGTPFWLMVIFVAFIGGFIYGPVGLIGLQALDLSPRNVAGTAAGFTGLFGYLLGA
TLASTGVGFLVKFAGWNVTFIVFLVFTVLILVIFQVIWREEKKLMQERALKLEQGV

Sequences:

>Translated_456_residues
MFAWLQAPGPAAPLSAEQVDRTYPRMRLQVFMGIFLGYAGFYLIRNNISAIAPLLIDESGAIDKPAIGIIGNAVLVSYGL
SKFFSAMVSDRSNARYFLPLGLALSALMNLVVAFVPWVSASVGVFATVMFLNGWFQGMGYPPCGRIVVQWFSTSERGWKG
SLWNTSHNLGAFGLPVLVGIGLSMTGENWRAAYWLPALVALVVALVAFLLIRDNPQSVGLPPIDDYRNDPAKVAEDTGEK
ISTKDLVFKHILHSRIIMLLAIANVFVYALRYGVLHWITTYLSEQHHMSIGSGLIGFAAFELAGFIGTVLCGWLSDNVFK
GNRSAAISLFTLGAGLSIAAYWLAPVGTPFWLMVIFVAFIGGFIYGPVGLIGLQALDLSPRNVAGTAAGFTGLFGYLLGA
TLASTGVGFLVKFAGWNVTFIVFLVFTVLILVIFQVIWREEKKLMQERALKLEQGV
>Mature_456_residues
MFAWLQAPGPAAPLSAEQVDRTYPRMRLQVFMGIFLGYAGFYLIRNNISAIAPLLIDESGAIDKPAIGIIGNAVLVSYGL
SKFFSAMVSDRSNARYFLPLGLALSALMNLVVAFVPWVSASVGVFATVMFLNGWFQGMGYPPCGRIVVQWFSTSERGWKG
SLWNTSHNLGAFGLPVLVGIGLSMTGENWRAAYWLPALVALVVALVAFLLIRDNPQSVGLPPIDDYRNDPAKVAEDTGEK
ISTKDLVFKHILHSRIIMLLAIANVFVYALRYGVLHWITTYLSEQHHMSIGSGLIGFAAFELAGFIGTVLCGWLSDNVFK
GNRSAAISLFTLGAGLSIAAYWLAPVGTPFWLMVIFVAFIGGFIYGPVGLIGLQALDLSPRNVAGTAAGFTGLFGYLLGA
TLASTGVGFLVKFAGWNVTFIVFLVFTVLILVIFQVIWREEKKLMQERALKLEQGV

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=412, Percent_Identity=29.8543689320388, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI4503847, Length=412, Percent_Identity=29.8543689320388, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI256219483, Length=412, Percent_Identity=29.8543689320388, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI256219543, Length=433, Percent_Identity=28.6374133949192, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI256219564, Length=342, Percent_Identity=29.2397660818713, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI223717983, Length=412, Percent_Identity=22.3300970873786, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38093649, Length=483, Percent_Identity=21.5320910973085, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788573, Length=447, Percent_Identity=44.2953020134228, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI87082310, Length=424, Percent_Identity=35.1415094339623, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI2367259, Length=466, Percent_Identity=27.0386266094421, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789152, Length=309, Percent_Identity=25.2427184466019, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17542316, Length=456, Percent_Identity=24.1228070175439, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI133901856, Length=473, Percent_Identity=21.5644820295983, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI133901854, Length=473, Percent_Identity=21.5644820295983, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24656866, Length=498, Percent_Identity=21.8875502008032, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI45550478, Length=498, Percent_Identity=21.8875502008032, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24656861, Length=498, Percent_Identity=21.8875502008032, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49541; Mature: 49541

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAWLQAPGPAAPLSAEQVDRTYPRMRLQVFMGIFLGYAGFYLIRNNISAIAPLLIDESG
CCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
AIDKPAIGIIGNAVLVSYGLSKFFSAMVSDRSNARYFLPLGLALSALMNLVVAFVPWVSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
SVGVFATVMFLNGWFQGMGYPPCGRIVVQWFSTSERGWKGSLWNTSHNLGAFGLPVLVGI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
GLSMTGENWRAAYWLPALVALVVALVAFLLIRDNPQSVGLPPIDDYRNDPAKVAEDTGEK
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCHHHHHHHCCCC
ISTKDLVFKHILHSRIIMLLAIANVFVYALRYGVLHWITTYLSEQHHMSIGSGLIGFAAF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHH
ELAGFIGTVLCGWLSDNVFKGNRSAAISLFTLGAGLSIAAYWLAPVGTPFWLMVIFVAFI
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHH
GGFIYGPVGLIGLQALDLSPRNVAGTAAGFTGLFGYLLGATLASTGVGFLVKFAGWNVTF
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
IVFLVFTVLILVIFQVIWREEKKLMQERALKLEQGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFAWLQAPGPAAPLSAEQVDRTYPRMRLQVFMGIFLGYAGFYLIRNNISAIAPLLIDESG
CCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
AIDKPAIGIIGNAVLVSYGLSKFFSAMVSDRSNARYFLPLGLALSALMNLVVAFVPWVSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
SVGVFATVMFLNGWFQGMGYPPCGRIVVQWFSTSERGWKGSLWNTSHNLGAFGLPVLVGI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
GLSMTGENWRAAYWLPALVALVVALVAFLLIRDNPQSVGLPPIDDYRNDPAKVAEDTGEK
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCHHHHHHHCCCC
ISTKDLVFKHILHSRIIMLLAIANVFVYALRYGVLHWITTYLSEQHHMSIGSGLIGFAAF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHH
ELAGFIGTVLCGWLSDNVFKGNRSAAISLFTLGAGLSIAAYWLAPVGTPFWLMVIFVAFI
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHH
GGFIYGPVGLIGLQALDLSPRNVAGTAAGFTGLFGYLLGATLASTGVGFLVKFAGWNVTF
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
IVFLVFTVLILVIFQVIWREEKKLMQERALKLEQGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3329281; 9205837; 9278503; 3141744; 12893936 [H]