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The map label for this gene is deoC

Identifier: 38232894

GI number: 38232894

Start: 236460

End: 237116

Strand: Direct

Name: deoC

Synonym: DIP0273

Alternate gene names: 38232894

Gene position: 236460-237116 (Clockwise)

Preceding gene: 38232893

Following gene: 38232895

Centisome position: 9.5

GC content: 59.67

Gene sequence:

>657_bases
ATGACTACTCGCAACGACGTAGCCCAGATGATCGACCACACCCTGCTCAAGCCAGAGGCAACCACCGACGACTTCAAGGC
ACTCATCGCCGACGCCGTTCGCCTCGGCACCTACTCGGTATGCGTATCCCCATCCGCACTCCCAGTTGAGGTTCCAGAAA
ACCTCCACGTAGCAACTGTTGTGGGCTTCCCATCCGGCGCCGTCAAGCCAGAGATCAAGGCTGCTGAAGCTGCCCGCACT
GTTGCCGATGGTGCAGAAGAAGTCGACATGGTGATCAACATCGCCCTCGCCAAGGAAGGCAAGTTCGACGAGCTCGAGGC
CGAAATCAAGGCTGTTCGCGACGCCGTCCCAGCACCAGGAATCCTCAAGGTCATCCTCGAAACCGCAGCACTGACTGACG
ACGAAATCGTCGCAGCATGTAAGGCCTCCGAAAACGCTGGCGCAGACTTTGTCAAGACCTCCACCGGCTTCCATCCAGCA
GGTGGCGCAAGCGTTCACGCAGTGGAAATCATGCACGCAACCGTGGGCGGCCGCCTCGGAATCAAAGCCTCCGGCGGCAT
CCGCACCGCCAAGGATGCCCTCGCCATGATCGAAGCAGGCGCTACCCGCTTGGGTCTGTCTGCCTCCGCAGCCATTCTTG
AAGAACTAGGAGAGTAG

Upstream 100 bases:

>100_bases
ATTGCTGACCGCGCGCTCTTTAGCCGCGAAAAGGCCGCAGGCATCGATTCCGTAGCAAACCACTAAAACATCCACCCACT
TTTCAAGGAGACTCACCAAA

Downstream 100 bases:

>100_bases
AACAATCATGAGCTACGCAGAGCTAGAGCGCACAGCCCGCGAGTGGGCGGATCACGATCCCGACCCTCGCACCAAAGAAA
CCATCGAGGGCTGGCTTAAA

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTTRNDVAQMIDHTLLKPEATTDDFKALIADAVRLGTYSVCVSPSALPVEVPENLHVATVVGFPSGAVKPEIKAAEAART
VADGAEEVDMVINIALAKEGKFDELEAEIKAVRDAVPAPGILKVILETAALTDDEIVAACKASENAGADFVKTSTGFHPA
GGASVHAVEIMHATVGGRLGIKASGGIRTAKDALAMIEAGATRLGLSASAAILEELGE

Sequences:

>Translated_218_residues
MTTRNDVAQMIDHTLLKPEATTDDFKALIADAVRLGTYSVCVSPSALPVEVPENLHVATVVGFPSGAVKPEIKAAEAART
VADGAEEVDMVINIALAKEGKFDELEAEIKAVRDAVPAPGILKVILETAALTDDEIVAACKASENAGADFVKTSTGFHPA
GGASVHAVEIMHATVGGRLGIKASGGIRTAKDALAMIEAGATRLGLSASAAILEELGE
>Mature_217_residues
TTRNDVAQMIDHTLLKPEATTDDFKALIADAVRLGTYSVCVSPSALPVEVPENLHVATVVGFPSGAVKPEIKAAEAARTV
ADGAEEVDMVINIALAKEGKFDELEAEIKAVRDAVPAPGILKVILETAALTDDEIVAACKASENAGADFVKTSTGFHPAG
GASVHAVEIMHATVGGRLGIKASGGIRTAKDALAMIEAGATRLGLSASAAILEELGE

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=197, Percent_Identity=34.5177664974619, Blast_Score=85, Evalue=4e-17,
Organism=Escherichia coli, GI1790841, Length=205, Percent_Identity=33.6585365853659, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17533015, Length=213, Percent_Identity=32.3943661971831, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922098, Length=202, Percent_Identity=30.6930693069307, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_CORDI (Q6NJX0)

Other databases:

- EMBL:   BX248354
- RefSeq:   NP_938661.1
- ProteinModelPortal:   Q6NJX0
- SMR:   Q6NJX0
- GeneID:   2648850
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP0273
- NMPDR:   fig|257309.1.peg.252
- HOGENOM:   HBG636421
- OMA:   CGFPSGK
- PhylomeDB:   Q6NJX0
- ProtClustDB:   PRK00507
- BioCyc:   CDIP257309:DIP0273-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 22352; Mature: 22220

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: ACT_SITE 152-152 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRNDVAQMIDHTLLKPEATTDDFKALIADAVRLGTYSVCVSPSALPVEVPENLHVATV
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCEEECCCCCEEEEE
VGFPSGAVKPEIKAAEAARTVADGAEEVDMVINIALAKEGKFDELEAEIKAVRDAVPAPG
EECCCCCCCCCHHHHHHHHHHHCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCH
ILKVILETAALTDDEIVAACKASENAGADFVKTSTGFHPAGGASVHAVEIMHATVGGRLG
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCEEHEEEEEHHCCCCEE
IKASGGIRTAKDALAMIEAGATRLGLSASAAILEELGE
EEECCCCCHHHHHHHHHHCCCHHCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TTRNDVAQMIDHTLLKPEATTDDFKALIADAVRLGTYSVCVSPSALPVEVPENLHVATV
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCEEECCCCCEEEEE
VGFPSGAVKPEIKAAEAARTVADGAEEVDMVINIALAKEGKFDELEAEIKAVRDAVPAPG
EECCCCCCCCCHHHHHHHHHHHCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCCCCH
ILKVILETAALTDDEIVAACKASENAGADFVKTSTGFHPAGGASVHAVEIMHATVGGRLG
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCEEHEEEEEHHCCCCEE
IKASGGIRTAKDALAMIEAGATRLGLSASAAILEELGE
EEECCCCCHHHHHHHHHHCCCHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910