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The map label for this gene is pepO [H]

Identifier: 38232779

GI number: 38232779

Start: 124561

End: 126570

Strand: Reverse

Name: pepO [H]

Synonym: DIP0154

Alternate gene names: 38232779

Gene position: 126570-124561 (Counterclockwise)

Preceding gene: 38232783

Following gene: 38232777

Centisome position: 5.09

GC content: 57.76

Gene sequence:

>2010_bases
ATGCGGTTACCCCCAATGTTGGATAACCTAACTAGAATGGCACGCATGAATGATAATCAGCACCGTTTTGCCCTGTCAGA
CCTCTACCGTTTTGTTAATGGCCCGTGGTTGGATTCTCATGTGATTCCAGAAGATCGTGGCGTGGATGGCATTTTCCATG
GACTGCGGGATCGCGCGGAAGAAGATGTGCACACGATCGTGATGGATTCTGCTGATTCGCTGGCCGGCAAGTTGTATGCC
TCGTTCATGGATACCGAGGGTATCGAGTCGGCGGGCGTGGCGGCCCTGGATAAGGATCTCACGCTGATCGATGTTGCTAC
GGTGCCGGAGTTTGTTCAGGCCTTGGGTGCGTTGGATCGCGTGGGTGTGGGCGGACCCGTGGGGTTCTGGGTTGCGAAGG
ATTCTGCTGGTGACAAGTCCGTGGCTTATATCATGCAGTCCGGTATCACGTTGCCGGATGAGGCCTACTACCGTGAGGAG
TCTCATGCGCAGACGCGTGAGGCTTATCAAAAGCACGTGGAAAAGATGTTGGGTTTCCTTGCACCGGAGCAGCTGGGCAC
CACGCCTATCGACGCTGCCACGCGGATCCTGGCACTAGAGACTGATATTGCTGCTGCCCATTGGGATGTGGTGCAGCGTC
GAGATGCTGTAAAGACCTTCAATCCCACTGAGATGGCTGAGCTTCCGCCGCAGGTGGCAGCCCTGTTGCGTGCCGCTGGC
CTGCCGGAGCACCGTGTTATTTCCATGATGCCTTCCTACTTTGAGGCCCTAGAATCCCTGCTGACACCGCAGCGTCTTGA
TGATTGGAAACTGCTGACCACCTGGCGCATCCTGCATTCTCGTGCCGGTGTTCTCACCCCTGAGATTTCTCGCGCCGACT
TTGAGTTCTTTGGTACCACGCTCTCTGGTGCGACACAGCAGCGCGACCGCTGGAAGCGCGCCTTGGGGTTGGCGGAGTCT
TTCGTGGGTGAAGAAATCGGTGCGTTGTATGTGGAACGCCACTTCCCCGAGTCCTCTAAAAAAGATATGCTTTCGCTGGT
CAGCTACCTTATCGAGGCCTACCGTGAGCGTATCAGCGGGTTGTCGTGGATGACGCCGGAGACTCGTGAGCGCGCGTTGG
ACAAGCTGGACAAGTTCAATGCCAAGATCGGCTATCCAGATTCTTGGCGCAGCTACGCCGGCTTGGAGTTCAGTGCCAAG
GGCACAGACCTCCTTGATAACGTTCGCGCTGGTTCTGCCTTTGCCCACGACTATGAGCTGAACAAGATTGGGCGGTTGGC
GGATCGCAACGAGTGGGTCACCACCCCGCAAACCGTCAATGCGTTTTATAACCCCGTGGTCAATGACATCACCTTCCCTG
CGGCTATTCTGCGGGCGCCGTTCTATTCGCCTGATGCCGATGCGGCTGAAAACTTTGGTGCTATCGGCGCGGTGATTGGC
CATGAGATCGGCCACGGTTTTGACGACCAAGGTTCGCAGTACGACGGCCACGGCAACCTGCAGTCGTGGTGGACCGACGA
GGACCGTGCTGCTTTCAGCGCTCTCACGGATCGTCTGGTTGAGCAGTTCGAGGGCTTGGTTCCGAGTGTGCTCGCGGACA
ACAACCCCAGCGGTGCGGGTGTAAATGGCCGGTTTACCTTGGGTGAAAACATCGGTGACCTCGGCGGATTGGGTATCGCG
GTCATCGCTTATCGACGCTACCTCGCCGACCACGGCCTCGATTTCGATTCCACCCCGCTGGCTGCTTTCCACGCCGAAGA
TGCCGACCCAGAACTGGAAAAGACCCAGTTCACTGGCCTACAGCGCCTGTTCCTCGCATGGGCACGCGTGTGGCGCACGG
CGATTCGTCCAGAGCTTGCGGCACAGTACCTCGCCATTGATCCGCACTCCCCTGCCGAGTTCCGCTGCAACGTGATTGCC
GGAAACGTCGCCGAGTTCTACCAAGCCTTCGACGTGGCAGAGGACTCCCCCATGTGGATCGCCCCAGAAAAGCGAGTCAC
TATCTGGTAG

Upstream 100 bases:

>100_bases
AGTGATCACTCCTAGTGCGAGCAGGCTCCATGTCTTGGCCGTCACCGCCGGCCGGAATTGATAATGCGACATAAAGTACA
ACCTACTAGGTCATCGTGAC

Downstream 100 bases:

>100_bases
CCCTTGGTTAAATATCGTGCCAGCTGAGCTCCGCTGCGATGAGAACGGTTTTAGGAGACATCACCACAGAGCCGTTCAAT
CGCATGGGCGAGATGTTATG

Product: putative endopeptidase

Products: NA

Alternate protein names: Endopeptidase O [H]

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MRLPPMLDNLTRMARMNDNQHRFALSDLYRFVNGPWLDSHVIPEDRGVDGIFHGLRDRAEEDVHTIVMDSADSLAGKLYA
SFMDTEGIESAGVAALDKDLTLIDVATVPEFVQALGALDRVGVGGPVGFWVAKDSAGDKSVAYIMQSGITLPDEAYYREE
SHAQTREAYQKHVEKMLGFLAPEQLGTTPIDAATRILALETDIAAAHWDVVQRRDAVKTFNPTEMAELPPQVAALLRAAG
LPEHRVISMMPSYFEALESLLTPQRLDDWKLLTTWRILHSRAGVLTPEISRADFEFFGTTLSGATQQRDRWKRALGLAES
FVGEEIGALYVERHFPESSKKDMLSLVSYLIEAYRERISGLSWMTPETRERALDKLDKFNAKIGYPDSWRSYAGLEFSAK
GTDLLDNVRAGSAFAHDYELNKIGRLADRNEWVTTPQTVNAFYNPVVNDITFPAAILRAPFYSPDADAAENFGAIGAVIG
HEIGHGFDDQGSQYDGHGNLQSWWTDEDRAAFSALTDRLVEQFEGLVPSVLADNNPSGAGVNGRFTLGENIGDLGGLGIA
VIAYRRYLADHGLDFDSTPLAAFHAEDADPELEKTQFTGLQRLFLAWARVWRTAIRPELAAQYLAIDPHSPAEFRCNVIA
GNVAEFYQAFDVAEDSPMWIAPEKRVTIW

Sequences:

>Translated_669_residues
MRLPPMLDNLTRMARMNDNQHRFALSDLYRFVNGPWLDSHVIPEDRGVDGIFHGLRDRAEEDVHTIVMDSADSLAGKLYA
SFMDTEGIESAGVAALDKDLTLIDVATVPEFVQALGALDRVGVGGPVGFWVAKDSAGDKSVAYIMQSGITLPDEAYYREE
SHAQTREAYQKHVEKMLGFLAPEQLGTTPIDAATRILALETDIAAAHWDVVQRRDAVKTFNPTEMAELPPQVAALLRAAG
LPEHRVISMMPSYFEALESLLTPQRLDDWKLLTTWRILHSRAGVLTPEISRADFEFFGTTLSGATQQRDRWKRALGLAES
FVGEEIGALYVERHFPESSKKDMLSLVSYLIEAYRERISGLSWMTPETRERALDKLDKFNAKIGYPDSWRSYAGLEFSAK
GTDLLDNVRAGSAFAHDYELNKIGRLADRNEWVTTPQTVNAFYNPVVNDITFPAAILRAPFYSPDADAAENFGAIGAVIG
HEIGHGFDDQGSQYDGHGNLQSWWTDEDRAAFSALTDRLVEQFEGLVPSVLADNNPSGAGVNGRFTLGENIGDLGGLGIA
VIAYRRYLADHGLDFDSTPLAAFHAEDADPELEKTQFTGLQRLFLAWARVWRTAIRPELAAQYLAIDPHSPAEFRCNVIA
GNVAEFYQAFDVAEDSPMWIAPEKRVTIW
>Mature_669_residues
MRLPPMLDNLTRMARMNDNQHRFALSDLYRFVNGPWLDSHVIPEDRGVDGIFHGLRDRAEEDVHTIVMDSADSLAGKLYA
SFMDTEGIESAGVAALDKDLTLIDVATVPEFVQALGALDRVGVGGPVGFWVAKDSAGDKSVAYIMQSGITLPDEAYYREE
SHAQTREAYQKHVEKMLGFLAPEQLGTTPIDAATRILALETDIAAAHWDVVQRRDAVKTFNPTEMAELPPQVAALLRAAG
LPEHRVISMMPSYFEALESLLTPQRLDDWKLLTTWRILHSRAGVLTPEISRADFEFFGTTLSGATQQRDRWKRALGLAES
FVGEEIGALYVERHFPESSKKDMLSLVSYLIEAYRERISGLSWMTPETRERALDKLDKFNAKIGYPDSWRSYAGLEFSAK
GTDLLDNVRAGSAFAHDYELNKIGRLADRNEWVTTPQTVNAFYNPVVNDITFPAAILRAPFYSPDADAAENFGAIGAVIG
HEIGHGFDDQGSQYDGHGNLQSWWTDEDRAAFSALTDRLVEQFEGLVPSVLADNNPSGAGVNGRFTLGENIGDLGGLGIA
VIAYRRYLADHGLDFDSTPLAAFHAEDADPELEKTQFTGLQRLFLAWARVWRTAIRPELAAQYLAIDPHSPAEFRCNVIA
GNVAEFYQAFDVAEDSPMWIAPEKRVTIW

Specific function: Unknown

COG id: COG3590

COG function: function code O; Predicted metalloendopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M13 family [H]

Homologues:

Organism=Homo sapiens, GI116256333, Length=697, Percent_Identity=29.1248206599713, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI116256331, Length=697, Percent_Identity=29.1248206599713, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI116256329, Length=697, Percent_Identity=29.1248206599713, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI116256327, Length=697, Percent_Identity=29.1248206599713, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI239049391, Length=700, Percent_Identity=28.8571428571429, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI153945836, Length=684, Percent_Identity=28.2163742690059, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI82617560, Length=682, Percent_Identity=28.2991202346041, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI153945761, Length=682, Percent_Identity=28.2991202346041, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI153945771, Length=682, Percent_Identity=28.4457478005865, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI4503443, Length=690, Percent_Identity=27.6811594202899, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI164519138, Length=690, Percent_Identity=27.8260869565217, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI164519136, Length=690, Percent_Identity=27.6811594202899, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI164519140, Length=690, Percent_Identity=27.8260869565217, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI157426891, Length=691, Percent_Identity=28.5094066570188, Blast_Score=235, Evalue=1e-61,
Organism=Homo sapiens, GI90403592, Length=692, Percent_Identity=26.4450867052023, Blast_Score=210, Evalue=4e-54,
Organism=Homo sapiens, GI4557691, Length=380, Percent_Identity=24.2105263157895, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI86562497, Length=693, Percent_Identity=27.994227994228, Blast_Score=239, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17533333, Length=690, Percent_Identity=26.9565217391304, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI32563993, Length=631, Percent_Identity=27.4167987321712, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17564342, Length=439, Percent_Identity=32.3462414578588, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25148650, Length=381, Percent_Identity=31.496062992126, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17534401, Length=608, Percent_Identity=27.4671052631579, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71987442, Length=434, Percent_Identity=29.0322580645161, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17570047, Length=622, Percent_Identity=23.4726688102894, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71994787, Length=376, Percent_Identity=25.7978723404255, Blast_Score=105, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71998977, Length=337, Percent_Identity=27.299703264095, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71998975, Length=337, Percent_Identity=27.5964391691395, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI193204436, Length=339, Percent_Identity=26.2536873156342, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17533319, Length=355, Percent_Identity=24.2253521126761, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988640, Length=251, Percent_Identity=29.0836653386454, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17532485, Length=396, Percent_Identity=22.979797979798, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737761, Length=691, Percent_Identity=28.3646888567294, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24640050, Length=685, Percent_Identity=28.029197080292, Blast_Score=243, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24640052, Length=685, Percent_Identity=28.029197080292, Blast_Score=243, Evalue=4e-64,
Organism=Drosophila melanogaster, GI45551938, Length=564, Percent_Identity=29.0780141843972, Blast_Score=235, Evalue=9e-62,
Organism=Drosophila melanogaster, GI45550777, Length=564, Percent_Identity=29.0780141843972, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24643425, Length=688, Percent_Identity=24.8546511627907, Blast_Score=223, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24650487, Length=364, Percent_Identity=29.1208791208791, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24650889, Length=564, Percent_Identity=23.4042553191489, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI281362760, Length=568, Percent_Identity=22.1830985915493, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24650765, Length=380, Percent_Identity=26.8421052631579, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI221474862, Length=381, Percent_Identity=22.3097112860892, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355943, Length=522, Percent_Identity=23.1800766283525, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24650885, Length=328, Percent_Identity=25.9146341463415, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24650883, Length=330, Percent_Identity=24.5454545454545, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000718
- InterPro:   IPR018497
- InterPro:   IPR008753 [H]

Pfam domain/function: PF01431 Peptidase_M13; PF05649 Peptidase_M13_N [H]

EC number: NA

Molecular weight: Translated: 74308; Mature: 74308

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPPMLDNLTRMARMNDNQHRFALSDLYRFVNGPWLDSHVIPEDRGVDGIFHGLRDRAE
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
EDVHTIVMDSADSLAGKLYASFMDTEGIESAGVAALDKDLTLIDVATVPEFVQALGALDR
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHH
VGVGGPVGFWVAKDSAGDKSVAYIMQSGITLPDEAYYREESHAQTREAYQKHVEKMLGFL
CCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
APEQLGTTPIDAATRILALETDIAAAHWDVVQRRDAVKTFNPTEMAELPPQVAALLRAAG
CHHHHCCCCHHHHHHEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCC
LPEHRVISMMPSYFEALESLLTPQRLDDWKLLTTWRILHSRAGVLTPEISRADFEFFGTT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCH
LSGATQQRDRWKRALGLAESFVGEEIGALYVERHFPESSKKDMLSLVSYLIEAYRERISG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
LSWMTPETRERALDKLDKFNAKIGYPDSWRSYAGLEFSAKGTDLLDNVRAGSAFAHDYEL
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCEECCCCCHHHHHHCCCCCHHCCCCH
NKIGRLADRNEWVTTPQTVNAFYNPVVNDITFPAAILRAPFYSPDADAAENFGAIGAVIG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHH
HEIGHGFDDQGSQYDGHGNLQSWWTDEDRAAFSALTDRLVEQFEGLVPSVLADNNPSGAG
HHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
VNGRFTLGENIGDLGGLGIAVIAYRRYLADHGLDFDSTPLAAFHAEDADPELEKTQFTGL
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHH
QRLFLAWARVWRTAIRPELAAQYLAIDPHSPAEFRCNVIAGNVAEFYQAFDVAEDSPMWI
HHHHHHHHHHHHHHHCHHHHHHHEEECCCCCCCEEEEEEECCHHHHHHHHHCCCCCCEEE
APEKRVTIW
CCCCCEECC
>Mature Secondary Structure
MRLPPMLDNLTRMARMNDNQHRFALSDLYRFVNGPWLDSHVIPEDRGVDGIFHGLRDRAE
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
EDVHTIVMDSADSLAGKLYASFMDTEGIESAGVAALDKDLTLIDVATVPEFVQALGALDR
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHH
VGVGGPVGFWVAKDSAGDKSVAYIMQSGITLPDEAYYREESHAQTREAYQKHVEKMLGFL
CCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
APEQLGTTPIDAATRILALETDIAAAHWDVVQRRDAVKTFNPTEMAELPPQVAALLRAAG
CHHHHCCCCHHHHHHEEEEECHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHCC
LPEHRVISMMPSYFEALESLLTPQRLDDWKLLTTWRILHSRAGVLTPEISRADFEFFGTT
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCH
LSGATQQRDRWKRALGLAESFVGEEIGALYVERHFPESSKKDMLSLVSYLIEAYRERISG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
LSWMTPETRERALDKLDKFNAKIGYPDSWRSYAGLEFSAKGTDLLDNVRAGSAFAHDYEL
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCEECCCCCHHHHHHCCCCCHHCCCCH
NKIGRLADRNEWVTTPQTVNAFYNPVVNDITFPAAILRAPFYSPDADAAENFGAIGAVIG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHH
HEIGHGFDDQGSQYDGHGNLQSWWTDEDRAAFSALTDRLVEQFEGLVPSVLADNNPSGAG
HHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
VNGRFTLGENIGDLGGLGIAVIAYRRYLADHGLDFDSTPLAAFHAEDADPELEKTQFTGL
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHH
QRLFLAWARVWRTAIRPELAAQYLAIDPHSPAEFRCNVIAGNVAEFYQAFDVAEDSPMWI
HHHHHHHHHHHHHHHCHHHHHHHEEECCCCCCCEEEEEEECCHHHHHHHHHCCCCCCEEE
APEKRVTIW
CCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9726890 [H]