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The map label for this gene is uxuR [H]

Identifier: 38232653

GI number: 38232653

Start: 12176

End: 12904

Strand: Reverse

Name: uxuR [H]

Synonym: DIP0011

Alternate gene names: 38232653

Gene position: 12904-12176 (Counterclockwise)

Preceding gene: 38232654

Following gene: 38232650

Centisome position: 0.52

GC content: 56.79

Gene sequence:

>729_bases
TTGCACATGTCTCAATCCACCCAACGGGCCTATCAAGAAGTCCTAGATTGGCTGGAAAAAGAGCTGCGCAAAGGCTCCAT
TGCTATCGGCGACAAACTCCCCGGCGAACGCGCACTCGCAGAACAATTCGAACTCTCTAGGGCATCCGTACGCGAAGCCA
TCCGCATCCTCACTTCCATGGGACTCGTACGCACCGGCACCGGATCCGGCCCGCACTCCGGAGCGATCGTTATCTCCGAA
CCATCAGCAGGGCTCTCCTGGGCCATTCGCATGCATCTCAGCGCCCGATCACTCCCGCTTAAAGACCTCGTCAACACCTG
CATTCTCATCGAATCCAACGCAGCCGCCGACGCAGCCACTCCTAAGATCAGCCCAGACTCCCCCGAACGCAGCCACGTCC
TCAACGAAGCCCACCGACTTCTCGACAGCATGGACGACCCCACCCTGCCGTTCCACGACTACCACATCAAAGACGTCAAC
TTTCACATTCTGATCACCTCACTAGCAGGCAACCTCGTCACAGAAACCATCATGGAATCCCTGCGCTACTCCGCCATCGC
ATTCGTCATCGAACGACTCGCCATGCGCACCGACTGGGCAGAAGTATCAGAAAAACTACAACGCGAACACCGCAATATCC
TGCGCGCCATCGAAGAACGCAACCCAGATAAAGCCCGCACCCTCGTTCACGACCACATTGCGGATTTCTACGAGCTGACT
TCGCACTAA

Upstream 100 bases:

>100_bases
ACCAACACCATAACGGCACGACTTCCAAGGCACGTGGATTAGGATTACACCTAACACATCCACCCATATCCGCCCACATC
CGCCTTGAACAAGGGAGCCT

Downstream 100 bases:

>100_bases
ACACAAGCACGCTTATCGACGTTTCCCACTGCGGCTCTTCCCCAACCGCGAACTCGAGTTCAAGACTGCGAAAACCCAAG
GACAGCACTCGCGCGGCATA

Product: putative regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MHMSQSTQRAYQEVLDWLEKELRKGSIAIGDKLPGERALAEQFELSRASVREAIRILTSMGLVRTGTGSGPHSGAIVISE
PSAGLSWAIRMHLSARSLPLKDLVNTCILIESNAAADAATPKISPDSPERSHVLNEAHRLLDSMDDPTLPFHDYHIKDVN
FHILITSLAGNLVTETIMESLRYSAIAFVIERLAMRTDWAEVSEKLQREHRNILRAIEERNPDKARTLVHDHIADFYELT
SH

Sequences:

>Translated_242_residues
MHMSQSTQRAYQEVLDWLEKELRKGSIAIGDKLPGERALAEQFELSRASVREAIRILTSMGLVRTGTGSGPHSGAIVISE
PSAGLSWAIRMHLSARSLPLKDLVNTCILIESNAAADAATPKISPDSPERSHVLNEAHRLLDSMDDPTLPFHDYHIKDVN
FHILITSLAGNLVTETIMESLRYSAIAFVIERLAMRTDWAEVSEKLQREHRNILRAIEERNPDKARTLVHDHIADFYELT
SH
>Mature_242_residues
MHMSQSTQRAYQEVLDWLEKELRKGSIAIGDKLPGERALAEQFELSRASVREAIRILTSMGLVRTGTGSGPHSGAIVISE
PSAGLSWAIRMHLSARSLPLKDLVNTCILIESNAAADAATPKISPDSPERSHVLNEAHRLLDSMDDPTLPFHDYHIKDVN
FHILITSLAGNLVTETIMESLRYSAIAFVIERLAMRTDWAEVSEKLQREHRNILRAIEERNPDKARTLVHDHIADFYELT
SH

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082208, Length=239, Percent_Identity=26.3598326359833, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27119; Mature: 27119

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMSQSTQRAYQEVLDWLEKELRKGSIAIGDKLPGERALAEQFELSRASVREAIRILTSM
CCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLVRTGTGSGPHSGAIVISEPSAGLSWAIRMHLSARSLPLKDLVNTCILIESNAAADAAT
CCCCCCCCCCCCCCEEEEECCCCCCEEHHEEECCCCCCCHHHHHHHHEEEECCCCCCCCC
PKISPDSPERSHVLNEAHRLLDSMDDPTLPFHDYHIKDVNFHILITSLAGNLVTETIMES
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEHHHHHHHHHHHHHHHHH
LRYSAIAFVIERLAMRTDWAEVSEKLQREHRNILRAIEERNPDKARTLVHDHIADFYELT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SH
CC
>Mature Secondary Structure
MHMSQSTQRAYQEVLDWLEKELRKGSIAIGDKLPGERALAEQFELSRASVREAIRILTSM
CCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLVRTGTGSGPHSGAIVISEPSAGLSWAIRMHLSARSLPLKDLVNTCILIESNAAADAAT
CCCCCCCCCCCCCCEEEEECCCCCCEEHHEEECCCCCCCHHHHHHHHEEEECCCCCCCCC
PKISPDSPERSHVLNEAHRLLDSMDDPTLPFHDYHIKDVNFHILITSLAGNLVTETIMES
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEEHHHHHHHHHHHHHHHHH
LRYSAIAFVIERLAMRTDWAEVSEKLQREHRNILRAIEERNPDKARTLVHDHIADFYELT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SH
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]