Click here to switch to the map view.

The map label for this gene is rsmB [H]

Identifier: 37681411

GI number: 37681411

Start: 3317044

End: 3318324

Strand: Direct

Name: rsmB [H]

Synonym: VV3227

Alternate gene names: 37681411

Gene position: 3317044-3318324 (Clockwise)

Preceding gene: 37681410

Following gene: 37681412

Centisome position: 98.88

GC content: 50.51

Gene sequence:

>1281_bases
ATGAATGTTCGCGCTGCGGCTGCCAACGTCTTGTATCAAGTTGTCGACCGAGGCAACTCTCTATCGACCGCCCTTCCTGA
AGCTCAACAATCCATTCGCCCTCGCGACCACGCCTTACTGCAAGAGATCTGCTACGGCGCGTTACGCTACCTGCCTCGTT
TAGAGAGCATTGCCGGTAAATTGATGGATAAGCCTCTCAAAGGTAAACAACGTGTTTTTCATCACCTCATTTTGGTTGGC
TTATACCAGTTAGGTCACATGCGCATTCCGGCGCACGCGGCGGTTGGTGAAACGGTGGAAGGTGCACAAGCGCTGAAAGG
GCCTCGCTTACGTGGCTTGATCAATGCGGTTTTACGCAACTATCAGCGTGAACAACAAGCATTGGATGAGTTTTCTGTCA
GCCACAATGCCGGCAAATACGTTCATCCAAGTTGGCTACTGAAAATCCTGCAAGATGCTTACCCTGAGCAATGGCAGACG
ATTGTTGAAGCCAACAATAACAAAGCGCCGATGTGGCTACGCGTGAATCACGCTCATCATGATCGCGACGAATATCTGCA
ACTGCTCAAAAATGCAAACATTGATAGCACCCTGCACAGTGAAGCGATGGACGCCATAAAATTGGCCGCCCCTTGTGATG
TACACAGCTTGCCAGGGTTTGAGCAAGGTTGGGTTTCTGTGCAAGATGCCGCCGCACAGCTATCGTTTAACTATCTACAA
CCTAAAGATGGCGAACTGATCCTCGATTGCTGCGCGGCACCTGGTGGCAAAACCGCGCACATTTTAGAACGAGTCTCTGC
TCGTGAAGTCGTGGCACTGGACTGCGATGAACAACGCTTGAAAAGAGTGACGGAAAACCTGAAACGCCTCAATCTTCAAG
CAAAAGTGATTTGCGGTGATGCACGCAATCCTGAACAATGGTGGCAAGGCGAGCAATTTGACCGTATTTTGCTCGATGCA
CCTTGCTCTGCAACCGGGGTGATTCGTCGTCACCCAGACATCAAATGGCTGCGAAGAGCAGAAGACATCACTGCGTTAGC
ACAGTTACAAAGCGAAATTTTTGATGCCATGTGGGCACAACTCAAGCCAGGTGGCACCTTGGTTTACGCCACTTGCTCAA
TCACGCCAATGGAAAATGTGGAGCAAGTGAAGGCGTTTCTCGCCAGAACCCCAGCAGCACAACTGGTTGGCTCTGAGCGC
GAAAATCCTGGTCGCCAAATTCTTCCCGGAGAGGAAGATATGGATGGCTTCTACTATGCCGTGCTAGTTAAGCAAGCATA
A

Upstream 100 bases:

>100_bases
GCAGTGTACTGAGTTAACCTGCCAAGCAATCGGGCATTTTTGCCCAGTTTAAGAACTTTACGAGGGCAGAGACGCCCTCT
TTAACTTTAAGGTACTCATC

Downstream 100 bases:

>100_bases
GTAAATGGGCGATTGAAGCCTCTTCAATCGCCTTTTTCGAATCACGAGAACAGAGTATGAAAATCATTATTCTTGGTGCA
GGTCAGGTGGGTGGCACACT

Product: sun protein

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MNVRAAAANVLYQVVDRGNSLSTALPEAQQSIRPRDHALLQEICYGALRYLPRLESIAGKLMDKPLKGKQRVFHHLILVG
LYQLGHMRIPAHAAVGETVEGAQALKGPRLRGLINAVLRNYQREQQALDEFSVSHNAGKYVHPSWLLKILQDAYPEQWQT
IVEANNNKAPMWLRVNHAHHDRDEYLQLLKNANIDSTLHSEAMDAIKLAAPCDVHSLPGFEQGWVSVQDAAAQLSFNYLQ
PKDGELILDCCAAPGGKTAHILERVSAREVVALDCDEQRLKRVTENLKRLNLQAKVICGDARNPEQWWQGEQFDRILLDA
PCSATGVIRRHPDIKWLRRAEDITALAQLQSEIFDAMWAQLKPGGTLVYATCSITPMENVEQVKAFLARTPAAQLVGSER
ENPGRQILPGEEDMDGFYYAVLVKQA

Sequences:

>Translated_426_residues
MNVRAAAANVLYQVVDRGNSLSTALPEAQQSIRPRDHALLQEICYGALRYLPRLESIAGKLMDKPLKGKQRVFHHLILVG
LYQLGHMRIPAHAAVGETVEGAQALKGPRLRGLINAVLRNYQREQQALDEFSVSHNAGKYVHPSWLLKILQDAYPEQWQT
IVEANNNKAPMWLRVNHAHHDRDEYLQLLKNANIDSTLHSEAMDAIKLAAPCDVHSLPGFEQGWVSVQDAAAQLSFNYLQ
PKDGELILDCCAAPGGKTAHILERVSAREVVALDCDEQRLKRVTENLKRLNLQAKVICGDARNPEQWWQGEQFDRILLDA
PCSATGVIRRHPDIKWLRRAEDITALAQLQSEIFDAMWAQLKPGGTLVYATCSITPMENVEQVKAFLARTPAAQLVGSER
ENPGRQILPGEEDMDGFYYAVLVKQA
>Mature_426_residues
MNVRAAAANVLYQVVDRGNSLSTALPEAQQSIRPRDHALLQEICYGALRYLPRLESIAGKLMDKPLKGKQRVFHHLILVG
LYQLGHMRIPAHAAVGETVEGAQALKGPRLRGLINAVLRNYQREQQALDEFSVSHNAGKYVHPSWLLKILQDAYPEQWQT
IVEANNNKAPMWLRVNHAHHDRDEYLQLLKNANIDSTLHSEAMDAIKLAAPCDVHSLPGFEQGWVSVQDAAAQLSFNYLQ
PKDGELILDCCAAPGGKTAHILERVSAREVVALDCDEQRLKRVTENLKRLNLQAKVICGDARNPEQWWQGEQFDRILLDA
PCSATGVIRRHPDIKWLRRAEDITALAQLQSEIFDAMWAQLKPGGTLVYATCSITPMENVEQVKAFLARTPAAQLVGSER
ENPGRQILPGEEDMDGFYYAVLVKQA

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=311, Percent_Identity=33.4405144694534, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI76150623, Length=311, Percent_Identity=33.4405144694534, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI32698918, Length=207, Percent_Identity=35.2657004830918, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI301336155, Length=209, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI39995082, Length=209, Percent_Identity=31.5789473684211, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI40316918, Length=184, Percent_Identity=30.9782608695652, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI11545785, Length=173, Percent_Identity=32.3699421965318, Blast_Score=73, Evalue=7e-13,
Organism=Escherichia coli, GI2367212, Length=426, Percent_Identity=59.8591549295775, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI87081985, Length=227, Percent_Identity=31.7180616740088, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17536757, Length=312, Percent_Identity=28.525641025641, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25143471, Length=296, Percent_Identity=29.0540540540541, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324268, Length=310, Percent_Identity=28.3870967741935, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319447, Length=274, Percent_Identity=28.1021897810219, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI22024126, Length=311, Percent_Identity=29.2604501607717, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI19920494, Length=164, Percent_Identity=32.9268292682927, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355201, Length=211, Percent_Identity=30.8056872037915, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356513, Length=164, Percent_Identity=33.5365853658537, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24668781, Length=164, Percent_Identity=34.7560975609756, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 47688; Mature: 47688

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVRAAAANVLYQVVDRGNSLSTALPEAQQSIRPRDHALLQEICYGALRYLPRLESIAGK
CCCHHHHHHHHHHHHHCCCCCHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LMDKPLKGKQRVFHHLILVGLYQLGHMRIPAHAAVGETVEGAQALKGPRLRGLINAVLRN
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHHH
YQREQQALDEFSVSHNAGKYVHPSWLLKILQDAYPEQWQTIVEANNNKAPMWLRVNHAHH
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEEECCCCC
DRDEYLQLLKNANIDSTLHSEAMDAIKLAAPCDVHSLPGFEQGWVSVQDAAAQLSFNYLQ
CHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PKDGELILDCCAAPGGKTAHILERVSAREVVALDCDEQRLKRVTENLKRLNLQAKVICGD
CCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCEEEEEECC
ARNPEQWWQGEQFDRILLDAPCSATGVIRRHPDIKWLRRAEDITALAQLQSEIFDAMWAQ
CCCHHHHCCCCCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKPGGTLVYATCSITPMENVEQVKAFLARTPAAQLVGSERENPGRQILPGEEDMDGFYYA
CCCCCEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
VLVKQA
EEEECC
>Mature Secondary Structure
MNVRAAAANVLYQVVDRGNSLSTALPEAQQSIRPRDHALLQEICYGALRYLPRLESIAGK
CCCHHHHHHHHHHHHHCCCCCHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LMDKPLKGKQRVFHHLILVGLYQLGHMRIPAHAAVGETVEGAQALKGPRLRGLINAVLRN
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHCCCHHHHHHHHHHHH
YQREQQALDEFSVSHNAGKYVHPSWLLKILQDAYPEQWQTIVEANNNKAPMWLRVNHAHH
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEEECCCCC
DRDEYLQLLKNANIDSTLHSEAMDAIKLAAPCDVHSLPGFEQGWVSVQDAAAQLSFNYLQ
CHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PKDGELILDCCAAPGGKTAHILERVSAREVVALDCDEQRLKRVTENLKRLNLQAKVICGD
CCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCEEEEEECC
ARNPEQWWQGEQFDRILLDAPCSATGVIRRHPDIKWLRRAEDITALAQLQSEIFDAMWAQ
CCCHHHHCCCCCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKPGGTLVYATCSITPMENVEQVKAFLARTPAAQLVGSERENPGRQILPGEEDMDGFYYA
CCCCCEEEEEEEECCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEE
VLVKQA
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA