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The map label for this gene is mcp4 [H]

Identifier: 37681324

GI number: 37681324

Start: 3223214

End: 3224863

Strand: Direct

Name: mcp4 [H]

Synonym: VV3140

Alternate gene names: 37681324

Gene position: 3223214-3224863 (Clockwise)

Preceding gene: 37681323

Following gene: 37681326

Centisome position: 96.09

GC content: 52.42

Gene sequence:

>1650_bases
GTGATTGGTATGGTCGGTTCTAGCTTGCGCGTCATTAACATCAAACAGCGACTTTATGTACTCACGTTCGTGATCACATC
ACTATTGCTGCTTCCATTTATCGCTCTGCTCTACGCCTATCAAAGTGATTTGATGGAAGCCAAGCAGGTCAAAACACGCC
ATTTGGTCGAAACGGCCGTGAGTTTGCAGCAGCACTATTATCAGCAAGAACAAGCCGGGCGCTTGTCTCGCGAAGAGGCG
CAAACGCAAGCCAAGGCGGCCATTAGCCAGCTGCGCTATGAAAAAGAAGATTACTTTTGGATTAACGATGATCAGCCCAA
TATGATCATGCACCCGATGAAACCGCAGCTGAACGGCAAGAGTTTAAGCGCAGTGAAAGATCCGACTGGCAAGGCGCTGT
TTGTTGAAATGGTTTCGGTGGCAAAAACATCCGGGGCTGGCTTTGTCCATTACATGTGGCCAAAGCCGGGTTCAGACGTC
GATGTGGAAAAAGTCTCTTATGTGCAAATGTTCCAGCCGTGGGGCTGGATTACCGGCAGTGGCGTTTATATCGATGATGT
CGAAGCGCTGGTGTGGCAGCGTATTCGCGCCTCCCTTCTCCAGTTGAGCCTTACAGGCGCAGTGATGTTGTTACTGGCTG
GCTGGATAGGCAACAGCATTACCCAGCCTTGTAGAGCGACGCAGCGCGCTTTAGAGGATATAGCACAAGGAGATGGCGAC
CTGACCAAGCAACTGCCTGCCGACGGCCAAGATGAGTTAGCGCAAATCGCCCGTGCGTTTAACCAATTCACCAGCAAGAT
CCGCCTCATCGTACAAGGCATTGCCCCTGTCACACGTGATGTCACCGGCTCTGCCTCTGAGCTGACCCAAGTGGCAAGAA
ATGCACTCGAAAAAGCCACCGCCCAGCAGCACTCGGTCGATTCCGTTGCCAGTGCCATGAAGCAACTGCACGACAGCAAT
ATGCAAGTGGCCGATTCGGCTCAAGAGGCAGCCAGTGCAGCGCAGGCTGCTGCAGAGAAAGGCAAAGAAGGCAGTGCCAT
CATTGAAAAAGCCTCTGGCTACATGCATGCCTTGTCACATACCGTGACCCAAACAGAGCTCAATGTGCAAGAGCTAGCCA
AAGAAACCCAAAAAGTAGGCTCAGTGTTGGAAGTTATCCGGGGTGTGGCCGAGCAAACCAATTTACTTGCGCTCAACGCA
GCCATAGAAGCCGCCCGAGCGGGTGAGCAAGGCCGTGGCTTTGCAGTGGTCGCTGACGAAGTACGCACATTGGCTACGCG
CACCAGCAGCAGTACCGATGAAATTCAACACATCATCGCGCAGTTGCAACAACGTGCCAACGATGTCTGTTTATCGATGG
AACAAACACAGCGTCAATCCACCGAAACCCAACAGCAAGCCAGCTTGGCACAGCAAGCCCTAAGTGATATCGATGCACAA
ATTGCTGTGATTCTACAGCTCAACCAGCACATTGCTCGTGCCAGCGGAGAGCAAACATCGGCCACTGAGCTCATTAACCA
CAATCTGCTGCACATTGTCGATCACAGTGAACAGACGGCAGCACAAGCCAATCAAGTCGCTGCGGCGAGCGAGCAGTTGA
TGGCTAGCGGTAACCAATTGCAAGTCAACTTTGCCGCGTTCAAGGTGTAA

Upstream 100 bases:

>100_bases
CTTTCAAATCTCGCCTTTCGTCGCATATACGAAGCTGTTATCAATTTGTTACATTGAAAAAACAATAACAATCAACAAAT
GTTTCCCAACCCTTCAAGGA

Downstream 100 bases:

>100_bases
CGCCAATAGAATGAACAAACTTACGATCGGCTTAGGTCATTAATGGCCTAAGCCGTCTGTTATTCTAAAGCAGCAAGAAT
GGAACAGTGGCTGGCATTGT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MIGMVGSSLRVINIKQRLYVLTFVITSLLLLPFIALLYAYQSDLMEAKQVKTRHLVETAVSLQQHYYQQEQAGRLSREEA
QTQAKAAISQLRYEKEDYFWINDDQPNMIMHPMKPQLNGKSLSAVKDPTGKALFVEMVSVAKTSGAGFVHYMWPKPGSDV
DVEKVSYVQMFQPWGWITGSGVYIDDVEALVWQRIRASLLQLSLTGAVMLLLAGWIGNSITQPCRATQRALEDIAQGDGD
LTKQLPADGQDELAQIARAFNQFTSKIRLIVQGIAPVTRDVTGSASELTQVARNALEKATAQQHSVDSVASAMKQLHDSN
MQVADSAQEAASAAQAAAEKGKEGSAIIEKASGYMHALSHTVTQTELNVQELAKETQKVGSVLEVIRGVAEQTNLLALNA
AIEAARAGEQGRGFAVVADEVRTLATRTSSSTDEIQHIIAQLQQRANDVCLSMEQTQRQSTETQQQASLAQQALSDIDAQ
IAVILQLNQHIARASGEQTSATELINHNLLHIVDHSEQTAAQANQVAAASEQLMASGNQLQVNFAAFKV

Sequences:

>Translated_549_residues
MIGMVGSSLRVINIKQRLYVLTFVITSLLLLPFIALLYAYQSDLMEAKQVKTRHLVETAVSLQQHYYQQEQAGRLSREEA
QTQAKAAISQLRYEKEDYFWINDDQPNMIMHPMKPQLNGKSLSAVKDPTGKALFVEMVSVAKTSGAGFVHYMWPKPGSDV
DVEKVSYVQMFQPWGWITGSGVYIDDVEALVWQRIRASLLQLSLTGAVMLLLAGWIGNSITQPCRATQRALEDIAQGDGD
LTKQLPADGQDELAQIARAFNQFTSKIRLIVQGIAPVTRDVTGSASELTQVARNALEKATAQQHSVDSVASAMKQLHDSN
MQVADSAQEAASAAQAAAEKGKEGSAIIEKASGYMHALSHTVTQTELNVQELAKETQKVGSVLEVIRGVAEQTNLLALNA
AIEAARAGEQGRGFAVVADEVRTLATRTSSSTDEIQHIIAQLQQRANDVCLSMEQTQRQSTETQQQASLAQQALSDIDAQ
IAVILQLNQHIARASGEQTSATELINHNLLHIVDHSEQTAAQANQVAAASEQLMASGNQLQVNFAAFKV
>Mature_549_residues
MIGMVGSSLRVINIKQRLYVLTFVITSLLLLPFIALLYAYQSDLMEAKQVKTRHLVETAVSLQQHYYQQEQAGRLSREEA
QTQAKAAISQLRYEKEDYFWINDDQPNMIMHPMKPQLNGKSLSAVKDPTGKALFVEMVSVAKTSGAGFVHYMWPKPGSDV
DVEKVSYVQMFQPWGWITGSGVYIDDVEALVWQRIRASLLQLSLTGAVMLLLAGWIGNSITQPCRATQRALEDIAQGDGD
LTKQLPADGQDELAQIARAFNQFTSKIRLIVQGIAPVTRDVTGSASELTQVARNALEKATAQQHSVDSVASAMKQLHDSN
MQVADSAQEAASAAQAAAEKGKEGSAIIEKASGYMHALSHTVTQTELNVQELAKETQKVGSVLEVIRGVAEQTNLLALNA
AIEAARAGEQGRGFAVVADEVRTLATRTSSSTDEIQHIIAQLQQRANDVCLSMEQTQRQSTETQQQASLAQQALSDIDAQ
IAVILQLNQHIARASGEQTSATELINHNLLHIVDHSEQTAAQANQVAAASEQLMASGNQLQVNFAAFKV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=233, Percent_Identity=34.7639484978541, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1788194, Length=339, Percent_Identity=30.3834808259587, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788195, Length=208, Percent_Identity=33.6538461538462, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787690, Length=350, Percent_Identity=28.8571428571429, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789453, Length=316, Percent_Identity=29.1139240506329, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59830; Mature: 59830

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGMVGSSLRVINIKQRLYVLTFVITSLLLLPFIALLYAYQSDLMEAKQVKTRHLVETAV
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLQQHYYQQEQAGRLSREEAQTQAKAAISQLRYEKEDYFWINDDQPNMIMHPMKPQLNGK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEECCCCCCCCCC
SLSAVKDPTGKALFVEMVSVAKTSGAGFVHYMWPKPGSDVDVEKVSYVQMFQPWGWITGS
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCC
GVYIDDVEALVWQRIRASLLQLSLTGAVMLLLAGWIGNSITQPCRATQRALEDIAQGDGD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
LTKQLPADGQDELAQIARAFNQFTSKIRLIVQGIAPVTRDVTGSASELTQVARNALEKAT
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AQQHSVDSVASAMKQLHDSNMQVADSAQEAASAAQAAAEKGKEGSAIIEKASGYMHALSH
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TVTQTELNVQELAKETQKVGSVLEVIRGVAEQTNLLALNAAIEAARAGEQGRGFAVVADE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHH
VRTLATRTSSSTDEIQHIIAQLQQRANDVCLSMEQTQRQSTETQQQASLAQQALSDIDAQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAVILQLNQHIARASGEQTSATELINHNLLHIVDHSEQTAAQANQVAAASEQLMASGNQL
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEE
QVNFAAFKV
EEEEEEECC
>Mature Secondary Structure
MIGMVGSSLRVINIKQRLYVLTFVITSLLLLPFIALLYAYQSDLMEAKQVKTRHLVETAV
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLQQHYYQQEQAGRLSREEAQTQAKAAISQLRYEKEDYFWINDDQPNMIMHPMKPQLNGK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEECCCCCCCCCC
SLSAVKDPTGKALFVEMVSVAKTSGAGFVHYMWPKPGSDVDVEKVSYVQMFQPWGWITGS
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCC
GVYIDDVEALVWQRIRASLLQLSLTGAVMLLLAGWIGNSITQPCRATQRALEDIAQGDGD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
LTKQLPADGQDELAQIARAFNQFTSKIRLIVQGIAPVTRDVTGSASELTQVARNALEKAT
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AQQHSVDSVASAMKQLHDSNMQVADSAQEAASAAQAAAEKGKEGSAIIEKASGYMHALSH
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TVTQTELNVQELAKETQKVGSVLEVIRGVAEQTNLLALNAAIEAARAGEQGRGFAVVADE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCEEEEHHH
VRTLATRTSSSTDEIQHIIAQLQQRANDVCLSMEQTQRQSTETQQQASLAQQALSDIDAQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAVILQLNQHIARASGEQTSATELINHNLLHIVDHSEQTAAQANQVAAASEQLMASGNQL
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEE
QVNFAAFKV
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]