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The map label for this gene is galE [H]

Identifier: 37681210

GI number: 37681210

Start: 3105726

End: 3106736

Strand: Direct

Name: galE [H]

Synonym: VV3026

Alternate gene names: 37681210

Gene position: 3105726-3106736 (Clockwise)

Preceding gene: 37681209

Following gene: 37681222

Centisome position: 92.58

GC content: 49.16

Gene sequence:

>1011_bases
ATGAACATACTGGTCACCGGTGGCAGCGGTTATATTGGCAGCCACACCTGTATTCAGATGATCGAAGCAGGAATGACGCC
CATCATTTTGGACAATCTTTATAACAGCAAATTGCTGGTGCTCGATCGCATTGAACAGGTCACTGGCGTGCGCCCCGCTT
TCTATCAAGGTGACATTCGTGACAGCGAGATTCTGCAACACGTCTTTGCTCAGCACGATATCCAGGGCGTCATCCACTTT
GCAGGCCTAAAGGCAGTAGGAGAATCGGTTGAAAAACCTCTGATGTATTATGATAACAATGTGTCAGGCACCCTAAATCT
CGTACGAGAAATGGATAAAGCTGGTGTTAAGAGCCTTATTTTCAGTTCGTCAGCCACCGTCTATGGTGATCCAGCCTCCG
TACCAATCCGTGAAGATTTCCCAACCTCAGCCACCAACCCTTATGGGCGGAGCAAATTGATGGTGGAAGAGTGTCTGACT
GACTTCCACAAAGCCAATCCTGATTGGAGCATCACTCTGCTGCGTTATTTCAATCCCGTTGGCGCTCACGAGTCGGGTTT
GCTCGGTGAGGATCCTCAAGGCATTCCAAATAACTTATTGCCCTTTGTGGCTCAAGTTGCGGTTGGTCGACGCGAAAAGC
TAGGCGTATTTGGTGACGACTATCCAACACCCGATGGCACTGGGGTTCGTGATTACATTCACGTCATTGACCTTGCAGAC
GGTCATTTGGCGGCTTTGAATAAAGTGGGGCAGCAAGCAGGATTGCATATCTTTAACCTTGGTACTGGCCAAGGAAACAG
CGTACTTGAAATGGTCGCTGCTTTTGAAAAAGCGGCTCAGCGTCCGATTCCATACGAAATCAAACCTCGCCGTGCCGGTG
ATATTGCTGAATGCTGGGCCGATCCAGCCTATGCAGAACAAGTATTGGGATGGAAAGCGACACGCTCACTAGAGACCATG
GTGGTAGATACTTGGCGTTGGCAATCCAACAACCCAAATGGCTATGAGTAA

Upstream 100 bases:

>100_bases
AAATTGACTTTGCCCTATCCTGTTCATCGAGAATCTTTTCTAATAAACTCACAAAGTTAATTTGGCTAGATAATTGGAAA
TATAATTTCAGAGGACAACT

Downstream 100 bases:

>100_bases
CCGCCATCACTGACACATTTTACTGTATTGCTAACACAATAAGGGCGAGTGAAAACTCGCCTTTTGCTTTTGGGTACGAT
AGACATAGAGGTCAGATTAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNILVTGGSGYIGSHTCIQMIEAGMTPIILDNLYNSKLLVLDRIEQVTGVRPAFYQGDIRDSEILQHVFAQHDIQGVIHF
AGLKAVGESVEKPLMYYDNNVSGTLNLVREMDKAGVKSLIFSSSATVYGDPASVPIREDFPTSATNPYGRSKLMVEECLT
DFHKANPDWSITLLRYFNPVGAHESGLLGEDPQGIPNNLLPFVAQVAVGRREKLGVFGDDYPTPDGTGVRDYIHVIDLAD
GHLAALNKVGQQAGLHIFNLGTGQGNSVLEMVAAFEKAAQRPIPYEIKPRRAGDIAECWADPAYAEQVLGWKATRSLETM
VVDTWRWQSNNPNGYE

Sequences:

>Translated_336_residues
MNILVTGGSGYIGSHTCIQMIEAGMTPIILDNLYNSKLLVLDRIEQVTGVRPAFYQGDIRDSEILQHVFAQHDIQGVIHF
AGLKAVGESVEKPLMYYDNNVSGTLNLVREMDKAGVKSLIFSSSATVYGDPASVPIREDFPTSATNPYGRSKLMVEECLT
DFHKANPDWSITLLRYFNPVGAHESGLLGEDPQGIPNNLLPFVAQVAVGRREKLGVFGDDYPTPDGTGVRDYIHVIDLAD
GHLAALNKVGQQAGLHIFNLGTGQGNSVLEMVAAFEKAAQRPIPYEIKPRRAGDIAECWADPAYAEQVLGWKATRSLETM
VVDTWRWQSNNPNGYE
>Mature_336_residues
MNILVTGGSGYIGSHTCIQMIEAGMTPIILDNLYNSKLLVLDRIEQVTGVRPAFYQGDIRDSEILQHVFAQHDIQGVIHF
AGLKAVGESVEKPLMYYDNNVSGTLNLVREMDKAGVKSLIFSSSATVYGDPASVPIREDFPTSATNPYGRSKLMVEECLT
DFHKANPDWSITLLRYFNPVGAHESGLLGEDPQGIPNNLLPFVAQVAVGRREKLGVFGDDYPTPDGTGVRDYIHVIDLAD
GHLAALNKVGQQAGLHIFNLGTGQGNSVLEMVAAFEKAAQRPIPYEIKPRRAGDIAECWADPAYAEQVLGWKATRSLETM
VVDTWRWQSNNPNGYE

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=55.1319648093842, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=55.1319648093842, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=55.1319648093842, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI7657641, Length=352, Percent_Identity=26.1363636363636, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI42516563, Length=321, Percent_Identity=22.7414330218069, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=61.6071428571429, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=24.7933884297521, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994969, Length=364, Percent_Identity=24.1758241758242, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=49.5652173913044, Blast_Score=357, Evalue=6e-99,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=49.1379310344828, Blast_Score=356, Evalue=1e-98,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=49.5626822157434, Blast_Score=338, Evalue=6e-94,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=53.2163742690059, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI21356223, Length=337, Percent_Identity=24.9258160237389, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36877; Mature: 36877

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILVTGGSGYIGSHTCIQMIEAGMTPIILDNLYNSKLLVLDRIEQVTGVRPAFYQGDIR
CEEEEECCCCCCCHHHHHHHHHHCCCEEEEHHCCCCEEHHHHHHHHHHCCCCCCCCCCCC
DSEILQHVFAQHDIQGVIHFAGLKAVGESVEKPLMYYDNNVSGTLNLVREMDKAGVKSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHH
FSSSATVYGDPASVPIREDFPTSATNPYGRSKLMVEECLTDFHKANPDWSITLLRYFNPV
HCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHCCCC
GAHESGLLGEDPQGIPNNLLPFVAQVAVGRREKLGVFGDDYPTPDGTGVRDYIHVIDLAD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHEEEEECCC
GHLAALNKVGQQAGLHIFNLGTGQGNSVLEMVAAFEKAAQRPIPYEIKPRRAGDIAECWA
CHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHC
DPAYAEQVLGWKATRSLETMVVDTWRWQSNNPNGYE
CHHHHHHHHHHHHHCCHHEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MNILVTGGSGYIGSHTCIQMIEAGMTPIILDNLYNSKLLVLDRIEQVTGVRPAFYQGDIR
CEEEEECCCCCCCHHHHHHHHHHCCCEEEEHHCCCCEEHHHHHHHHHHCCCCCCCCCCCC
DSEILQHVFAQHDIQGVIHFAGLKAVGESVEKPLMYYDNNVSGTLNLVREMDKAGVKSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHH
FSSSATVYGDPASVPIREDFPTSATNPYGRSKLMVEECLTDFHKANPDWSITLLRYFNPV
HCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHCCCC
GAHESGLLGEDPQGIPNNLLPFVAQVAVGRREKLGVFGDDYPTPDGTGVRDYIHVIDLAD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHEEEEECCC
GHLAALNKVGQQAGLHIFNLGTGQGNSVLEMVAAFEKAAQRPIPYEIKPRRAGDIAECWA
CHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHC
DPAYAEQVLGWKATRSLETMVVDTWRWQSNNPNGYE
CHHHHHHHHHHHHHCCHHEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]