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The map label for this gene is rpiA [H]

Identifier: 37681034

GI number: 37681034

Start: 2907099

End: 2907761

Strand: Direct

Name: rpiA [H]

Synonym: VV2850

Alternate gene names: 37681034

Gene position: 2907099-2907761 (Clockwise)

Preceding gene: 37681033

Following gene: 37681036

Centisome position: 86.66

GC content: 48.27

Gene sequence:

>663_bases
ATGAGCATGACTCAAGATGAAATGAAAAAAGCCGCTGGTTGGGCAGCGCTCAAGTATGTGGAAAAAGGCAGCATTGTTGG
CGTAGGAACGGGCTCAACGGTTAATCACTTCATCGATGCTCTTGGAACCATGAGTGAAGAGATCAAAGGTGCGGTATCCA
GTTCTGTTGCATCAACAGAAAAACTTGAAGCGCTAGGCATTAAAATTTTCGACTGCAATGAAGTCGCCTCTTTAGACATT
TACGTTGATGGCGCGGACGAAATCAACGCCGATCGTGAAATGATCAAAGGCGGTGGCGCGGCGCTCACTCGCGAGAAGAT
CGTTGCAGCGATTGCGGACAAGTTTATCTGTATCGTTGATGGCACAAAGGCTGTCGATGTTCTTGGGACTTTCCCTCTTC
CTGTTGAAGTCATCCCAATGGCTCGCTCATACGTTGCGCGTCAATTGGTTAAACTTGGTGGCGATCCTTGTTACCGCGAA
GGGGTGATTACTGACAACGGTAACGTCATCCTTGATGTTTACGGTATGAAGATCACCAATCCAAAACAGCTGGAAGATCA
GATCAACGCTATTCCAGGCGTAGTGACTGTCGGTCTTTTTGCTCATCGCGGTGCTGACGTGGTCATCACCGGCACTCCAG
AAGGTGCCAAAATTGAGGAATAA

Upstream 100 bases:

>100_bases
TTGCCTAAGATCGTGACCCCAAGCCAAATCTGGCAATGGGAAAACGACGTTTAACTCGTTATAATCGCGCGGCACAAACT
ATCCTTCATCAATTCAGGAG

Downstream 100 bases:

>100_bases
ATAGCTGGTTTTGCGCTATTTTCCGTTATTTGATTACAGACGGCGCCCAAGGGCGCCGTTTTTTATGACTTTCTTGAAGA
AAATTATCTCTTATTCCGTA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSMTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEEIKGAVSSSVASTEKLEALGIKIFDCNEVASLDI
YVDGADEINADREMIKGGGAALTREKIVAAIADKFICIVDGTKAVDVLGTFPLPVEVIPMARSYVARQLVKLGGDPCYRE
GVITDNGNVILDVYGMKITNPKQLEDQINAIPGVVTVGLFAHRGADVVITGTPEGAKIEE

Sequences:

>Translated_220_residues
MSMTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEEIKGAVSSSVASTEKLEALGIKIFDCNEVASLDI
YVDGADEINADREMIKGGGAALTREKIVAAIADKFICIVDGTKAVDVLGTFPLPVEVIPMARSYVARQLVKLGGDPCYRE
GVITDNGNVILDVYGMKITNPKQLEDQINAIPGVVTVGLFAHRGADVVITGTPEGAKIEE
>Mature_219_residues
SMTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEEIKGAVSSSVASTEKLEALGIKIFDCNEVASLDIY
VDGADEINADREMIKGGGAALTREKIVAAIADKFICIVDGTKAVDVLGTFPLPVEVIPMARSYVARQLVKLGGDPCYREG
VITDNGNVILDVYGMKITNPKQLEDQINAIPGVVTVGLFAHRGADVVITGTPEGAKIEE

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=228, Percent_Identity=36.4035087719298, Blast_Score=114, Evalue=7e-26,
Organism=Escherichia coli, GI1789280, Length=215, Percent_Identity=74.8837209302326, Blast_Score=331, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI17551758, Length=210, Percent_Identity=33.8095238095238, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324669, Length=225, Percent_Identity=30.6666666666667, Blast_Score=83, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281364072, Length=207, Percent_Identity=32.8502415458937, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23204; Mature: 23073

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEEIKGAVSSSVASTE
CCCCHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLEALGIKIFDCNEVASLDIYVDGADEINADREMIKGGGAALTREKIVAAIADKFICIVD
HHHHHCEEEEECCCEEEEEEEECCCHHCCCCHHHHCCCCCHHHHHHHHHHHHCCEEEEEC
GTKAVDVLGTFPLPVEVIPMARSYVARQLVKLGGDPCYREGVITDNGNVILDVYGMKITN
CCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHCCEEECCCCEEEEEECEEECC
PKQLEDQINAIPGVVTVGLFAHRGADVVITGTPEGAKIEE
HHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
SMTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEEIKGAVSSSVASTE
CCCHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLEALGIKIFDCNEVASLDIYVDGADEINADREMIKGGGAALTREKIVAAIADKFICIVD
HHHHHCEEEEECCCEEEEEEEECCCHHCCCCHHHHCCCCCHHHHHHHHHHHHCCEEEEEC
GTKAVDVLGTFPLPVEVIPMARSYVARQLVKLGGDPCYREGVITDNGNVILDVYGMKITN
CCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHCCEEECCCCEEEEEECEEECC
PKQLEDQINAIPGVVTVGLFAHRGADVVITGTPEGAKIEE
HHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA