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The map label for this gene is kefA [C]

Identifier: 37679894

GI number: 37679894

Start: 1765131

End: 1766012

Strand: Direct

Name: kefA [C]

Synonym: VV1710

Alternate gene names: 37679894

Gene position: 1765131-1766012 (Clockwise)

Preceding gene: 37679893

Following gene: 37679897

Centisome position: 52.62

GC content: 47.96

Gene sequence:

>882_bases
ATGAATAAGAAACTCTACGCGCTATTCGCCGCGGCTTTGATCTCGGCACCGGCCTTCGCGACGGAAGAAATCGCCAATAT
GGAAAACATTCAGCAATTTGCCAGCTTGATCCGCTGGAGCGGTGTGTTCTTCTCTGTCATCATCATCGCCATTACTTGGC
TACTGTTGAAGTTCATGAATTCAATGGTAGAGAGCATTGGCGGCCAGTTTGCGCAGTATCGAATGCTGTTGCAGAAAACC
CAATCGTTCTTACAGTTCTTCATCTACTTAACCGCTGGCCTTGTGGTGTTTATGATGAGCTTTCGCATCAACGACCATAT
CTTAGCCTTAATTGGTGGTACGTTGGCGGTGTCGGTTGGTTTTGCGTTGAAAGACTTAGCCGCGTCATTTATTGCCGGAT
TGACGGTGATGATTGACCGTCCGTTTCAGGTGGGTGACCGCGTCACGTTTGAAGGCAACTATGGTGACATCATCGCGATT
GGCCTTCGCTCTGTACGAATGAGAACACTGACCGATGACATCATTACCATTCCGAACAACAAGTTTCTCAATGAAGTGAC
GGTCAGTGGAAACTATGGCGCACTCGACATGCAGGTGGTGATCCCCTTCTATGTCGGTATGGATGAAGATATTGTGCTCG
CGCGTGAGTTGATTCAGGAAGCGGCTTCGTCTAGCCGTTACATCCATCTACCAAAACCGGTGGTGGTACTGGTGAAGCAG
ACGATCACGGACAACTATTTGGCCATCCAGTTAACCTGCAAAGCCTACGTGGTGGATACTGCGTATGAAAAACTGTTTGA
ATCCGACATTACATTGCGTGTAATGAAAGAGTTTAAGAAGCATGGCATCAAACCACCGAGAATTGCATTCAGCGGCCAAT
AG

Upstream 100 bases:

>100_bases
GGCTTTATTGCTTGGAATGAGGATAAAGCTCGCGTCTCGGACCATTGGTTCCGCTACATTACCAACGTTCTCGATCGTCA
ACATTTGCTGGTGAAGTAAT

Downstream 100 bases:

>100_bases
ACATTGGACCAATAAGCATCAATAGACCACTCAAACAAAAAAGCTCTGTCGCATCGACAGAGCTTTTCTTTATGCCTATC
CATACCGCTATTGAATCAGT

Product: small-conductance mechanosensitive channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MNKKLYALFAAALISAPAFATEEIANMENIQQFASLIRWSGVFFSVIIIAITWLLLKFMNSMVESIGGQFAQYRMLLQKT
QSFLQFFIYLTAGLVVFMMSFRINDHILALIGGTLAVSVGFALKDLAASFIAGLTVMIDRPFQVGDRVTFEGNYGDIIAI
GLRSVRMRTLTDDIITIPNNKFLNEVTVSGNYGALDMQVVIPFYVGMDEDIVLARELIQEAASSSRYIHLPKPVVVLVKQ
TITDNYLAIQLTCKAYVVDTAYEKLFESDITLRVMKEFKKHGIKPPRIAFSGQ

Sequences:

>Translated_293_residues
MNKKLYALFAAALISAPAFATEEIANMENIQQFASLIRWSGVFFSVIIIAITWLLLKFMNSMVESIGGQFAQYRMLLQKT
QSFLQFFIYLTAGLVVFMMSFRINDHILALIGGTLAVSVGFALKDLAASFIAGLTVMIDRPFQVGDRVTFEGNYGDIIAI
GLRSVRMRTLTDDIITIPNNKFLNEVTVSGNYGALDMQVVIPFYVGMDEDIVLARELIQEAASSSRYIHLPKPVVVLVKQ
TITDNYLAIQLTCKAYVVDTAYEKLFESDITLRVMKEFKKHGIKPPRIAFSGQ
>Mature_293_residues
MNKKLYALFAAALISAPAFATEEIANMENIQQFASLIRWSGVFFSVIIIAITWLLLKFMNSMVESIGGQFAQYRMLLQKT
QSFLQFFIYLTAGLVVFMMSFRINDHILALIGGTLAVSVGFALKDLAASFIAGLTVMIDRPFQVGDRVTFEGNYGDIIAI
GLRSVRMRTLTDDIITIPNNKFLNEVTVSGNYGALDMQVVIPFYVGMDEDIVLARELIQEAASSSRYIHLPKPVVVLVKQ
TITDNYLAIQLTCKAYVVDTAYEKLFESDITLRVMKEFKKHGIKPPRIAFSGQ

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1786670, Length=201, Percent_Identity=23.3830845771144, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367355, Length=204, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 32770; Mature: 32770

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKLYALFAAALISAPAFATEEIANMENIQQFASLIRWSGVFFSVIIIAITWLLLKFMN
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMVESIGGQFAQYRMLLQKTQSFLQFFIYLTAGLVVFMMSFRINDHILALIGGTLAVSVG
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
FALKDLAASFIAGLTVMIDRPFQVGDRVTFEGNYGDIIAIGLRSVRMRTLTDDIITIPNN
HHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCCEEEEHHHHHHHHHHCCCEEECCCC
KFLNEVTVSGNYGALDMQVVIPFYVGMDEDIVLARELIQEAASSSRYIHLPKPVVVLVKQ
CCCCEEEECCCCCEEEHEEEEEHHCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHH
TITDNYLAIQLTCKAYVVDTAYEKLFESDITLRVMKEFKKHGIKPPRIAFSGQ
HHCCCEEEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECCCC
>Mature Secondary Structure
MNKKLYALFAAALISAPAFATEEIANMENIQQFASLIRWSGVFFSVIIIAITWLLLKFMN
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMVESIGGQFAQYRMLLQKTQSFLQFFIYLTAGLVVFMMSFRINDHILALIGGTLAVSVG
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
FALKDLAASFIAGLTVMIDRPFQVGDRVTFEGNYGDIIAIGLRSVRMRTLTDDIITIPNN
HHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCCEEEEHHHHHHHHHHCCCEEECCCC
KFLNEVTVSGNYGALDMQVVIPFYVGMDEDIVLARELIQEAASSSRYIHLPKPVVVLVKQ
CCCCEEEECCCCCEEEHEEEEEHHCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHH
TITDNYLAIQLTCKAYVVDTAYEKLFESDITLRVMKEFKKHGIKPPRIAFSGQ
HHCCCEEEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]