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The map label for this gene is fnr [H]

Identifier: 37679863

GI number: 37679863

Start: 1732908

End: 1733654

Strand: Direct

Name: fnr [H]

Synonym: VV1679

Alternate gene names: 37679863

Gene position: 1732908-1733654 (Clockwise)

Preceding gene: 37679862

Following gene: 37679864

Centisome position: 51.66

GC content: 41.37

Gene sequence:

>747_bases
ATGATTTCTGAAAAACCTGCGACAAAGCGCATCCAATCAGGTGGTTGTGCGATTCATTGTCAAGATTGTAGTATCAGCCA
ACTGTGTATTCCGTTTACATTAAACGAAGCTGAATTGGATCAACTCGATCAAATTATCGAACGTAAAAAGCCGATCCAAA
AAGGTCAAGAGTTATTCAAAGCCGGTGATGATCTAAAATCTCTTTACGCAATTCGTTCTGGTACGATTAAAAGCTACACA
ATTACCGAGCAGGGTGATGAGCAGATTACGGCTTTCCACTTGGCTGGAGATTTAGTTGGTTTTGATGCAATTACAGGTGA
TAGCCACCCTAGTTTTGCTCAGGCATTAGAAACTTCAATGGTTTGTGAGATTCCTTACGAAATTCTTGATGACCTTTCAG
GAAAGATGCCTAAGCTTCGTCAACAAATCATGCGCCTGATGAGTAATGAAATCAAAGGTGACCAAGAAATGATTTTGTTA
CTTTCGAAGAAGAATGCAGAAGAGCGTTTAGCCGCATTTTTGTACAATCTATCTACCCGTTTCTCGCAACGTGGCTTTAG
TCCGCGTGAGTTTCGTTTGACCATGACTCGTGGTGATATTGGTAATTACCTAGGTCTTACTGTCGAAACGATCAGCCGCC
TTCTTGGCCGTTTCCAGAAGTCAGAGATTCTTAGTGTAAAAGGTAAGTACATTACGATTCTTGACCACGATGCACTGATG
GAACTTGCTGGCGTATCAAAAGAGTAA

Upstream 100 bases:

>100_bases
ACTTGATCAACTAACCTGAAGATGACGCACTTTTTTTTACTATCCTTTAGTATTAACCAGTGCTAAAATATTGACGTATA
TCAAATAGTGAAAGGTTGTT

Downstream 100 bases:

>100_bases
ATCTCTACTGCGACGTAGCTCAACCCTGAGCTACGTCATGTTTTTCTTCATTATCTTCCTAATGTCCTAATATTTCTCTC
TTTTCTACGCTAAAGTATTC

Product: fumarate/nitrate reduction transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MISEKPATKRIQSGGCAIHCQDCSISQLCIPFTLNEAELDQLDQIIERKKPIQKGQELFKAGDDLKSLYAIRSGTIKSYT
ITEQGDEQITAFHLAGDLVGFDAITGDSHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILL
LSKKNAEERLAAFLYNLSTRFSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILDHDALM
ELAGVSKE

Sequences:

>Translated_248_residues
MISEKPATKRIQSGGCAIHCQDCSISQLCIPFTLNEAELDQLDQIIERKKPIQKGQELFKAGDDLKSLYAIRSGTIKSYT
ITEQGDEQITAFHLAGDLVGFDAITGDSHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILL
LSKKNAEERLAAFLYNLSTRFSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILDHDALM
ELAGVSKE
>Mature_248_residues
MISEKPATKRIQSGGCAIHCQDCSISQLCIPFTLNEAELDQLDQIIERKKPIQKGQELFKAGDDLKSLYAIRSGTIKSYT
ITEQGDEQITAFHLAGDLVGFDAITGDSHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILL
LSKKNAEERLAAFLYNLSTRFSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILDHDALM
ELAGVSKE

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=248, Percent_Identity=85.8870967741936, Blast_Score=438, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27774; Mature: 27774

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISEKPATKRIQSGGCAIHCQDCSISQLCIPFTLNEAELDQLDQIIERKKPIQKGQELFK
CCCCCCCHHHHHCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHH
AGDDLKSLYAIRSGTIKSYTITEQGDEQITAFHLAGDLVGFDAITGDSHPSFAQALETSM
CCHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEHHHHHCCCCCCCCCCHHHHHHHHHHH
VCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILLLSKKNAEERLAAFLYNLSTR
HHCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
FSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILDHDALM
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECHHHHH
ELAGVSKE
HHHCCCCC
>Mature Secondary Structure
MISEKPATKRIQSGGCAIHCQDCSISQLCIPFTLNEAELDQLDQIIERKKPIQKGQELFK
CCCCCCCHHHHHCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHH
AGDDLKSLYAIRSGTIKSYTITEQGDEQITAFHLAGDLVGFDAITGDSHPSFAQALETSM
CCHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEHHHHHCCCCCCCCCCHHHHHHHHHHH
VCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILLLSKKNAEERLAAFLYNLSTR
HHCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
FSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILDHDALM
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECHHHHH
ELAGVSKE
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA