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The map label for this gene is hpcD [H]

Identifier: 37679770

GI number: 37679770

Start: 1628616

End: 1629008

Strand: Direct

Name: hpcD [H]

Synonym: VV1586

Alternate gene names: 37679770

Gene position: 1628616-1629008 (Clockwise)

Preceding gene: 37679769

Following gene: 37679771

Centisome position: 48.55

GC content: 47.84

Gene sequence:

>393_bases
GTGCCACATTTTATTATGGAGTATTCGCCAAACGTTGAAACGGATATCGATATTCCGGCTTTGATGCAGGCGATTCACCG
CGAAGCGATTGACACAGGCGTGTTCCCGAAAGGCGGAATTCGTACCCGTGCAATCAAATGCGATTACTACTTGGTTGCTG
ACGAAGATCCGGAAAACCGCTTTATCCACCTCACAGCAAAGGTTGGTGTGGGGCGAGACATGGAAACCTTGCAAAATGCA
GCCCAGCGAGTATTCGATGTGTATTGCGAGTTCTTGTCTGAAGCGTTTGAGACGCACTACCTCAGCATTGGCTTTGAGAT
GGTCGAACTTCATCCGCAACTGAATTTCAAGAAGAACAATATTCACCAAAAACTGGCGCAGGCTTCTCAGTAG

Upstream 100 bases:

>100_bases
CACGACTTGCACCGCGTGCCAACGCTTGGCAAGTAAGCGAAGAAGAACCGAAGACATAGCTAATCTCGGGCTCTGACACG
GAGCCCGAAAGGAGAACAAA

Downstream 100 bases:

>100_bases
CTTCAGGCAAAAGTGGTTTAGGAAAGAGTAGATGGATCAGCTTAGCTATGTGGTGATGACGATATTGCCAGTGTTTCTGG
TTATTGGTGTTGGCTATGTT

Product: 5-carboxymethyl-2-hydroxymuconate isomerase

Products: NA

Alternate protein names: 5-carboxymethyl-2-hydroxymuconic acid isomerase; CHM isomerase; CHMI [H]

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MPHFIMEYSPNVETDIDIPALMQAIHREAIDTGVFPKGGIRTRAIKCDYYLVADEDPENRFIHLTAKVGVGRDMETLQNA
AQRVFDVYCEFLSEAFETHYLSIGFEMVELHPQLNFKKNNIHQKLAQASQ

Sequences:

>Translated_130_residues
MPHFIMEYSPNVETDIDIPALMQAIHREAIDTGVFPKGGIRTRAIKCDYYLVADEDPENRFIHLTAKVGVGRDMETLQNA
AQRVFDVYCEFLSEAFETHYLSIGFEMVELHPQLNFKKNNIHQKLAQASQ
>Mature_129_residues
PHFIMEYSPNVETDIDIPALMQAIHREAIDTGVFPKGGIRTRAIKCDYYLVADEDPENRFIHLTAKVGVGRDMETLQNAA
QRVFDVYCEFLSEAFETHYLSIGFEMVELHPQLNFKKNNIHQKLAQASQ

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET) [H]

COG id: COG3232

COG function: function code E; 5-carboxymethyl-2-hydroxymuconate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004220
- InterPro:   IPR014347 [H]

Pfam domain/function: PF02962 CHMI [H]

EC number: =5.3.3.10 [H]

Molecular weight: Translated: 14930; Mature: 14799

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHFIMEYSPNVETDIDIPALMQAIHREAIDTGVFPKGGIRTRAIKCDYYLVADEDPENR
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEECCCCCCC
FIHLTAKVGVGRDMETLQNAAQRVFDVYCEFLSEAFETHYLSIGFEMVELHPQLNFKKNN
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHH
IHQKLAQASQ
HHHHHHHCCC
>Mature Secondary Structure 
PHFIMEYSPNVETDIDIPALMQAIHREAIDTGVFPKGGIRTRAIKCDYYLVADEDPENR
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEEEECCCCCCC
FIHLTAKVGVGRDMETLQNAAQRVFDVYCEFLSEAFETHYLSIGFEMVELHPQLNFKKNN
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHH
IHQKLAQASQ
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194841; 2261999; 8547259 [H]