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The map label for this gene is cspA [H]

Identifier: 37679688

GI number: 37679688

Start: 1537783

End: 1537995

Strand: Direct

Name: cspA [H]

Synonym: VV1504

Alternate gene names: 37679688

Gene position: 1537783-1537995 (Clockwise)

Preceding gene: 37679686

Following gene: 37679689

Centisome position: 45.84

GC content: 39.91

Gene sequence:

>213_bases
ATGTCTGGTAAAATGACTGGTACAGTAAAATGGTTCAACGAGACTAAAGGTTTTGGTTTTATTTCTCAAGACAACGGCGG
CAAAGATGTATTCGTACACTTCCGTGCTATCGTTTCTGAAGGCTTCAAAACTCTTGCTGAAGGTCAGAAAGTAAGCTTCA
ACGTTGAAGAAGGTCAAAAAGGCCCACAAGCTTCTAACGTTACAGTTATCTAA

Upstream 100 bases:

>100_bases
GATATACCTCGTTAAACCTGCGTAAACTTTCTCTCGATAGACCATTCATGCACTTGTAATAGCCAGAAATGTTTAATGTA
AATTTTTAATAGAGGTCACT

Downstream 100 bases:

>100_bases
GCTTATTTTACTTGTGGTTTGACCACGAGAAGAATATTAAACGGGTGCTCGAAAGAGCACCCGTTTTTCGTTGGTATTTA
GAGAAAGTTTGTCTTAACGA

Product: cold shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 70; Mature: 69

Protein sequence:

>70_residues
MSGKMTGTVKWFNETKGFGFISQDNGGKDVFVHFRAIVSEGFKTLAEGQKVSFNVEEGQKGPQASNVTVI

Sequences:

>Translated_70_residues
MSGKMTGTVKWFNETKGFGFISQDNGGKDVFVHFRAIVSEGFKTLAEGQKVSFNVEEGQKGPQASNVTVI
>Mature_69_residues
SGKMTGTVKWFNETKGFGFISQDNGGKDVFVHFRAIVSEGFKTLAEGQKVSFNVEEGQKGPQASNVTVI

Specific function: Binds To And Stimulates The Transcription Of The CCAAT- Containing, Cold-Shock-Inducible Promoters Of The H-Ns And Gyra Proteins. Binds Also To The Inverted Repeat 5'-ATTGG-3'. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Escherichia coli, GI1789979, Length=70, Percent_Identity=68.5714285714286, Blast_Score=102, Evalue=5e-24,
Organism=Escherichia coli, GI2367114, Length=70, Percent_Identity=64.2857142857143, Blast_Score=97, Evalue=2e-22,
Organism=Escherichia coli, GI1787839, Length=69, Percent_Identity=63.768115942029, Blast_Score=95, Evalue=1e-21,
Organism=Escherichia coli, GI1788126, Length=67, Percent_Identity=67.1641791044776, Blast_Score=94, Evalue=2e-21,
Organism=Escherichia coli, GI1786841, Length=67, Percent_Identity=62.6865671641791, Blast_Score=92, Evalue=7e-21,
Organism=Escherichia coli, GI1787834, Length=70, Percent_Identity=61.4285714285714, Blast_Score=89, Evalue=6e-20,
Organism=Escherichia coli, GI1787107, Length=64, Percent_Identity=50, Blast_Score=73, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7600; Mature: 7468

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKMTGTVKWFNETKGFGFISQDNGGKDVFVHFRAIVSEGFKTLAEGQKVSFNVEEGQK
CCCCCCEEEEECCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEECCCCCC
GPQASNVTVI
CCCCCCEEEC
>Mature Secondary Structure 
SGKMTGTVKWFNETKGFGFISQDNGGKDVFVHFRAIVSEGFKTLAEGQKVSFNVEEGQK
CCCCCEEEEECCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHCCCEEEEECCCCCC
GPQASNVTVI
CCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]